Objective To explore the application effects of transitional care base on mobile APP for perianal abscess patients with postoperative rehabilitation. Methods A total of 97 perianal abscess patients, who were treated in the Department of Integrated Chinese and Western Medicine of West China Hospital of Sichuan University from February 2015 to February 2016, were divided into observation group (n=49) and control group (n=48) by the random number table. Patients in the control group were followed up by phone call, while patients in the observation group were given transitional care based on mobile APP with apricot trees-chart file. Wexner incontinence score, clinical recovery time and postoperative abscess recurrence rate, wound false-healing rate and the incidence of anal fistula were compared between the two groups after discharge. Results One month after discharge, the anus Wexner score of patients in observation group was (7.51±1.60) and the wound healing time was (20.71±2.48) d, which were all lower than that of the control group, and the differences were statistically significant (t=7.355,15.291; P< 0.01). The recurrence rate of abscess in the observation group was 2.0%, the rate of wound pseudo-healing was 8.2%, the incidence of anal fistula was 16.3%, and the control group was 14.6%, 27.1% and 37.5%, the two groups had statistically significant differences (χ2= 5.603, 6.005, 5.541; P< 0.05). Conclusions Transitional care base on mobile APP can effectively reduce complications and improve anal function recovery in patients with perianal abscess patients.