Unilateral spatial neglect is an important factor for affecting the brain damage,especially in patients with functional recovery after stroke.Seeking for the effective rehabilitation measles of unilateral spatial neglect has an important significance for improving the quality of life in patients.Currently,prism adaptation is the most widely used and well-studied treatment for unilateral spatial neglect,however,there is less domestic research in this field.This article reviews the advances in research on the therapeutic mechanism of prism adaptation for unilateral spatial neglect,the application in unilateral spatial neglect after stroke as well as its efficacy.