Objective To study the effect of body mass index(BMI)on the outcomes of women on their childbirth.Methods 800 women on their childbirth were divided into three groups(thin group,normal group and overweight group)according to their pre-pregnancy BMI.We evaluated the relationship of pregnancy BMI and childbirth outcomes.Meanwhile,in order to analyze the relationship between childbirth outcomes and the increase of BMI during pregnancy,these women were divided into another three groups(group A,BMI increased by ＜5; group B,BMI increased by 5 ～7; group C,BMI increased by ＞7).The relationship between BMI increase during pregnancy and outcomes of pregnancy was investigated.Results The rates of macroeosmia and cesarean section in overweight group were statistically higher than that in thin group and normal group.The difference in these rates was not statistically significant between normal group and thin group.In women with big BMI increase during pregnancy,the incidences of macrocosmia and cesarean section were statistically significantly higher than that of the other two groups(P ＜ 0.05).No difference was found for the rates of postpartum hemorrhages,labor durations of vaginal delivery between the three groups.Conclusion Prepregnancy overweight and high BMI increase have significant influence on the rates of macrocosmia and cesarean section in primipara.

Objective To observe the effect of Yingliu mixture combined with methimazole on autoantibodies and traditional Chinese medical syndromes of patients with Graves’ disease ( GD) . Methods A randomized, paralleled and controlled trial was carried out in 92 GD patients. The patients were evenly randomized into treatment group and control group, and were separately treated with Yingliu mixture combined with methimazole, and methimazole. The treatment for both groups lasted 12 weeks, and forty patients in each group completed the whole treatment. The changes of thyroid function, thyroid autoantibodies, and traditional Chinese medical syndrome scores were observed before and after treatment, and the clinical efficacy was also evaluated. Results (1) After treatment for 12 weeks, serum levels of thyroid peroxidase antibody (TPOAb), thyroglobulin antibody ( TGAb) and thyrotrophin receptor antibody ( TRAb) were decreased, and thyroid stimulating hormone ( TSH) was increased obviously in both groups after treatment ( P<0.01 compared with those before treatment) . The treatment group has better effect on improving TGAb and TRAb than the control group ( P<0.05). ( 2) Compared with those before treatment, the total scores of clinical symptoms and signs were decreased in the two groups at different time points of treatment course ( P<0.001) , and the decrease value in the treatment group was larger than that in the control group ( P<0.05) . ( 3) The total effective rate of the treatment group was 92.50%, higher than 82.50% of the control group ( P<0.05) . Conclusion Yingliu mixture combined with methimazole is effective on improving thyroid function, decreasing autoantibodies levels and relieving clinical symptoms and signs, and has better effect than methimazole alone for the treatment of GD.