Objective To investigate clinical significance of soluble CD30/CD30L and CD40/CD40L system imbalance in ovarian serous tumors.Methods 40 patients of serous cystadenoma and 30 patients of serous cystadenocarcinoma were selected,and 40 age-and weight-matched healthy women were also recruited as the control group.Peripheral venous blood (3 ml) of the healthy control and patients with ovarian serous tumors before surgery and 7 days after surgery were collected.After separation of serum,ELISA was used to detect levels of sCD30,sCD30L,sCD40 and sCD40L.Results Compared to the control group,levels of sCD30,sCD30L,sCD40 and sCD40L in both serous cystadenoma and serous cystadenocarcinoma groups were significantly in creased (P＜0.05).And in those serous cystadenocarcinoma group,levels of such soluble proteins were much higher than in serous cystadenoma group (P＜0.05).7 days after surgery,levels of such soluble proteins were significantly decreased in both serous cystadenoma and serous cystadenocarcinoma groups (P＜0.05).Conclusion Detection of serum sCD30/sCD30L and sCD40/sCD40L is possible to have a certain guiding significance to early diagnosis of ovarian tumors and the prognosis of patients.

Objective To explore the influence of the hospital-community integrated nursing on PICC management of tumor patients undergoing chemotherapy. Methods A total of 126 patients were randomly divided into control group and experimental group on average from June 2013 to June 2014, and the patients of control group used routine care while the patients of experimental group adopted hospital-community integrated nursing. We compared the incidence of PICC complications and health status, in which health status assessed by SF-36. Results After implementation of hospital-community integrated nursing, the incidence of durative staxis, infection and phlebitis in the experimental group were lower than those of the control group, and the total complication incidences (11. 11%) were lower than 53. 97% of the control group (P<0. 05). Each scores of health status items in the experimental group was better than that of the control group as well (P <0. 05). Conclusions The hospital-community integrated nursing can increase the nursing quality of community hospital and the quality of life of patients, and play a positive role on integrating medical resources and protect the benefits of patients.