Objective To make a method to determine trace iron (FeⅢ)in human hair. Methods Based on the coloured reaction between XO and Fe(Ⅲ)in the medium of HAc-NaAc(pH=3.2)with the presence of OP, FeⅢ was determined by spetrophotometry. Results It was found that when pH=3.2 and in the presence of OP, iron(Ⅲ) reacted with XO to form a stationary complex. The maximum absorption wave of Fe(Ⅲ)-XO was 570 nm, as OP was added, it moved to 590 nm, and the sensitivity was increased obviously when the molar absorptivity of the complex reached 3.67?105 L/(mol?cm) from 3.04?104 L/(mol?cm), the linear range for the content of Fe(Ⅲ)was 0.0～0.8 ?g/ml(0.0～20.0 ?g/25 ml), the regression equation of calibration graph was A=0.00236+0.542c(?g/25 ml)with a correlation coefficient of 0.997 6, detection limit was 6.09?10-6 g/L, RSD=0.97% and rate of recovery was 96%-99%. Conclusion The method can be used for the determination of trace iron(Ⅲ)in human hair samples.

Objective:To investigate the relationship between microalbuminuria(MAU)and obesity in Chongqing natives.Methods: Four hundred and seventy eight subjects over 30 years old were selected at random from health examination population.They were divided into 3 groups according to the Body Mass Index(BMI)diagnostic standard of〈The Guide of control and prevention of overweight and obesity in Chinese aduhs〉,control group(Con group),over weight group(Ow group)and obesity group(Oh group).MAU were tested in all groups and invested with every item in Ob group.Results:The prevalences of over weight and obesity in the present study were 40.0% and 7.3% respectively.The MAU in Ob group was more than that in Con group (P

OObjective] To explore the version and academic achievements of“Yan Hou Lun”. [Method] Finding of the bibliography of books about the version, one by one to check. And analyse the content of the book, summarize the academic achievement.[Result] There are three versions. This book has written tonsillitis, and other common diseases of throat. Diagnosis of disease, according to the lesion site and colour and lustre. It promotes the use of external power.[Conclusion]It can be divided into two versions of the system. It is a throat book appearing earlier, has a certain clinical practicability.

Objective To explore the clinical curative effect of central venous catheter drainage in treating pleural effusion.Methods 100 cases with pleural effusion were treated by the central venous catheter drainage.The curative effect,complications and adverse reactions were observed.Results Ater treatment for 12 ～ 28d,catheter drainage of 100 patients were all successful at the first time.The clinical effect:completely relieve 40 cases(40.0％),clinical partial remission 47 cases(47.0％),inefficient 13 cases (13.0％),and the total effective rate was 87.0％.There were some complications:pneumothorax 1 case,hemorrhage 2 cases,infection 1 case,pleural reaction 3 cases,pain 3 cases,subcutaneous emphysema 2 cases and take off the tube 1 case,the incidence rate of complications was 13.0％.Conclusion Central venous catheter drainage in t.reating pleural effusion has significant curative effect,which is worthy of clinical application.

Adenoviridae ; genetics ; Animals ; Dental Research ; Genetic Therapy ; Genetic Vectors ; History, 20th Century ; Humans ; National Institute of Dental and Craniofacial Research (U.S.) ; history ; organization & administration ; Salivary Gland Diseases ; therapy ; Salivary Glands ; cytology ; growth & development ; injuries ; physiology ; United States

Automated body fluid cytology analysis has been accepted by clinical laboratories gradually.The improvement of efficacy and analytical precision can overcome some defects of traditional manual method,such as time-consuming and poor repeatability.To make use of the advantages of automated fluid cell analysis technology,the automated method and microscopic method must be combined by setting review rules.Meanwhile,more attentions must be paied to sample collection and specimen preservation at pre-analytical stage,verification of instrument performance at analytical stage and necessary clinical communication at post-analytical stage.Only if a complete system of quality management,standardization of procedures,result validation and interpretation is implemented in the routine work,the clinical significance of body fluid cytological analysis can be recognized in clinical practice.

OBJECTIVE: To study the bioequivalence of domestic oxcarbazepine dispersible tablets. METHODS: 20 healthy male volunteers were randomly given oxcarbazepine dispersible tablets (test tablet) and oxcarbazepine tablets (reference tablet) via p.o. The plasma concentration of active metabolite (MHD) of oxcarbazepine were determined by HPLC. 3p97 software was used to calculate pharmacokinetic parameters and the bioequivalence of oxcarbazepine were evaluated. RESULTS: After treatment main pharmacokinetic parameters of test tablet vs. reference tablet were as follows: Cmax(4.231?0.841) ?g?mL-1 vs. (4.350?0.861) ?g?mL-1; tmax(4.13?0.43) h vs. (4.28?0.44) h; t1/2(14.17?2.66) h vs. (14.44?2.09) h; AUC0～60 (113.00?22.25) mg?h?L-1 vs. (118.11?14.20) mg?h?L-1; AUC0～∞(126.35?20.94) mg?h?L-1 vs. (130.54?16.17) mg?h?L-1. The relative bioavailability of test tablet to reference tablet was (95.67?12.80)%. CONCLUSION: Two kinds of tablets were bioequivalent.

Aim To study mechanisms of Stigma Maydis Polysaccharide(SMPS) on weight loss in experimental animals. Methods Observe changes of gastric discharge, intestinal peristalsis, biliary secretion, weight of gallbladder, body weight, appetite and cholecystokinin(CCK)level in plasm of rats and mice after being administrated with SMPS. Results SMPS increased the gastric residual rate of methyl orange and the intestinal propulsive rate,advanced first time black dejecta,increased the quantity of dejecta,decreased the weight of gallbladder in mice. SMPS also inhibited appetite,decreased body weight,prolonged gastric emptying,accelerated the propulsion speed of intestinal contents,promoted the biliary secretion,increased CCK level in plasm. Conclusion Mechanisms of weight loss are probably related to the increasing of CCK level in plasm and prolonging of gastric emptying,appetite inhibition, accelerating of intestinal peristalsis,the quantity increasing of dejecta.

Following a brief introduction of relaxin family members, receptors and related signalling pathways,we review effects of relaxin on cardiovascular system,particularly,its anti-fibrotic action.The heart and vessels are target organs of relaxin.Recent studies have documented that the relaxin genes are upregulated in the diseased heart of humans and experimental animals.In several animal disease models,relaxin can reverse cardiac fibrosis.Relaxin may also indirectly promote myocardial regeneration and repair by suppressing fibrotic healing.Further research needs to focus on elucidating the exact mechanisms utilized by relaxin to induce these cardiac actions and translation of experimental findings to novel therapy of cardiovascular disease.

Objective To explore the current therapeutic strategy for community acquired pneumonia(CAP) in the tertiary hospitals in Beijing district,and provide the evidence-based medicine for recommending application of Chinese community acquired pneumonia(CAP) guideline in our country widely.Methods The data of 225 hospitalized CAP patients from July 1st,2002 to June 30,2004 was documented retrospectively. The patient's situation was scored by either Chinese CAP guideline or Fine's risk classification.The data was analyzed with SPSS 10.0 to identify the correlation between the results evaluated by the two guidelines,and the differences of the combining use of antibiotics and antibiotic selection between group 1 and group 2 classified by Chinese CAP guideline.Results There was a significantly statistical correlation between the two guidelines(P=0.0000).There was a significantly statistical difference both in alternative administration of single or combining antibiotics(P=0.0290) and alternative application of penicillin or the third generation of cephalosporins(P=0.0001,P=0.005,respectively) between hospitalized criteria mismatched and matched groups classified by Chinese CAP guideline.The ratio of using fluroquinolone in above two groups was significantly high compared with other reagents,and there was no significant difference between them(P=0.182).Conclusion There is significant correlation between Chinese CAP guideline and Fine's risk classification.Chinese CAP guideline can be used to distinguish CAP from different risk levels.It is necessary to enforce and standardize the CAP diagnosis and treatment guideline widely.