The myelodysplastic syndrome(MDS)is a group of clonal haematopoietic stem cell diseases characterized by ineffective haematopoiesis,dysplasia and aberrational expression of cell surface markers.Therefore,immunophenotyping of blast cells,granulocytes and monocytes is helpful to distinguish between MDS and non-MDS.The immunophenotyping is a complicated process.So the uniform diagnostic standard is the key to the comparabe and reliable results.

Objective To investigate the value of Multi-slice Spiral CT Angiography (MSCTA)in diagnosis of superior mesenteric artery (SMA)diseases.Methods The image features of SMA diseases in 40 patients were reviewed retrospectively using volume rendering (VR),multiplanar reconstruction (MPR),curved planar reconstruction (CPR),maximum intensity projection and other post-processing reconstruction technique.Results 16 patients have SMA ischemia including 8 cases of SMA acute occlusion;1 case of acute occlusion with small intestinal ischemic necrosis who has had surgery to remove the necrotic intestine.8 cases of SMA chronic occlusion;10 cases of spontaneous isolated dissection of SMA;7 cases of true aneurysm of SMA;1 case of SMA pseudoaneurysm associating with infective endocarditic;3 cases of SMA ulcer,including 1 case of inferior mesenteric artery (IMA)severe stenosis;2 cases of severe stenosis of celiac trunk;1 case of occlusion of IMA. In total of 40 cases,13 were with collateral circulation associating with SMA diseases,of which 4 were SMA chronic occlusion,3 were SMA acute occlusion,1 was spontaneous isolated dissection of SMA,1 was SMA pseudoaneurysm,1 was IMA stenosis,1 was IMA occlusion and 2 were celiac trunk severe stenosis,which was included collateral circulation of the anterior and posterior arterial arcades in 3 cases,collateral circulation of the dorsal pancreatic artery in 2 cases,Riolan’s arcade in 10 cases.Conclusion MSCT could clearly display SMA diseases and the establishment of collateral circulation,and evaluate intestinal ischemia.

Objective: To explore the impacts of demographic structure, environmental quality on household health care expenditures. Methods: Based on 2000-2010 inter-provincial panel data, the method of dynamic panel SYS GMM is used. Results:(1) The rise of elederly dependency ratio promotes residents’ health care expenditures; (2) the decline in juvenile dependency ratio is also the acceleration factor of health care expenditures; (3) the seriousness of environmental quality pollution expands the health care demand. Conclusion: To improve the health status residents, it is needed to implement the medical insurance system for the eldly, construct the health care insurance system for the children, besides, environment protection should be people oriented.

Objective The quantitation measurement of microalbuminuria was adopted to verify the feasibility of urinary microalbumin and ratio of mieroalbumin to creatinine (M/C) detection with dry hemieal method. Methods Totally 80 urine samples from the patients with clinically diagnosed dia-betes were tested by the immune quantitation method (immunoturhidimetric assay) and dry heroical method (HT2000 urine analyzer and test paper, Guilin Hnatong Company) simultaneously. Sarcosine oxidase method was applied to measuring creatinine level. Ten cases of outliers were removed. With the quantitation result of M/C as the reference standard, immune quatilyzation of the M/C as refer-ence, we compared and analyzed the results of the immune quantilization of urine microalbumin, those of the dry chemistry method and of the dry chemistry system detecting M/C. Results There was sig-nificant differences in test results of urinary microalbumin with the dry chemistry method and the im-mune quantitation method (P<0.01) The sensitivity, accuracy and Youden index of the microalbu-minuria testing had been observed to decrease in order in immune the dry chemistry method, the im-mune quantitation method and M/C quantitation detection method. Conclusion The sensitivity of semi-quantitation dry chemical method is satisfactory in detecting microalbumin, which may be used as a means of microalbumin screening. M/C detection with the dry chemical method isn't suitable for screening microalbumin in instant urine samples.

Some hormones and glucocorticoid in chronic strss feedback are demonstrated to have significant effects on cancer progression.Recently,as a typical neuropeptide,gastrin releasing peptide (GRP) could mediate chronic stress to promote carcinogenesis through four conceivable mechanisms,such as regulating circadian rhythms,suppressing immunity system,acting as a mitogenic effect and mediating cancer-related psychiatric disorders,et al.

Objective To explore the effects of self-management strategies on self-efficacy and selfmanagement behavior in female college students with primary dysmenorrhea.Methods Implementing the plan that the interventional group (n=195) received self-management strategies,while the control group (n =196) did not received any intervention.Followed up six months,the self-efficacy and self-management behaviors and Visual Analogue Scale/Score (VAS) of dysmenorrhea pain were compared between two groups before and after the intervention.Results At the 6th month of observation period,the scores of self-efficacy in the intervention group (2.61 ±0.48) were significantly improved compared with the baseline (2.37 ± 0.36) and the control group(2.43±0.46) (both P＜0.05).Besides taking medicine to alleviate dysmenorrhea,other items in the self-management behaviors were significantly higher than baseline and control group (both P＜ 0.05).The mean of dysmenorrhea pain VAS of 6th menstrual period in the intervention group was lower than baseline and the control group (P＜0.05).Conclusion The self-management strategies can effectively improve the self-efficacy and self-management behaviors among female college students,and alleviate the degree of dysmenorrhea pain.

Aim To study mechanisms of Stigma Maydis Polysaccharide(SMPS) on weight loss in experimental animals. Methods Observe changes of gastric discharge, intestinal peristalsis, biliary secretion, weight of gallbladder, body weight, appetite and cholecystokinin(CCK)level in plasm of rats and mice after being administrated with SMPS. Results SMPS increased the gastric residual rate of methyl orange and the intestinal propulsive rate,advanced first time black dejecta,increased the quantity of dejecta,decreased the weight of gallbladder in mice. SMPS also inhibited appetite,decreased body weight,prolonged gastric emptying,accelerated the propulsion speed of intestinal contents,promoted the biliary secretion,increased CCK level in plasm. Conclusion Mechanisms of weight loss are probably related to the increasing of CCK level in plasm and prolonging of gastric emptying,appetite inhibition, accelerating of intestinal peristalsis,the quantity increasing of dejecta.

OBJECTIVE:To observe the influence of Valsartan on the serum ET,CGRP levels,urinary protein and Q - Td of patients with CRF complicating hypertension.METHODS: CRF research group including 24 patients with CRF complicating hypertension receiving Valsartan 80mg/ d for 4 weeks; CRF control groups including 20 CRF patients with normal blood pressure; health group including 9 health people.The serum ET and CGRP levels, urinary protein, and Q - Td were measured.RESULTS: (l)The serum ET level of CRF patients was higher than that of health people;The serum ET level of CRF research group(before treatment) was higher than that of CRF control group and decreased after treatment of Valsartan.(2) The serum CGRP level of CRF patients was higher than that of health people .The serum of CGRP level of CRF research group (before treatment) was higher than that of CRF control group and continued to increase after treatment of Valsartan. (3) The content of urinary protein of CRF patients was significantly higher than that of health people.The content of urinary protien of CRF research group before treatment was higher than that of CRF control group and decreased after treatment of Valsartan. (4) The Q - Td of CRF research group was longer than that of health group and CRF control group.But the Q - Td of CRF research group did not change after treatment of Valsartan.CONCLUSION: Valsartan could effectively control blood pressure and decrease content of urinary protein, and delay the deterioration of renal function, but could not reverse the cardiovascular remoulding.

Objective To investigate the relationship between plasma visfatin levels and type 2 diabetes mellitus patients with carotid atherosclerosis.Methods 60 subjects were divided into 3 groups,T2DM no carotid atherosclerosis group (20 cases),T2DM with carotid atherosclerosis group (20 cases)and normal control group (20cases).Carotid IMT,plasma visfatin,waist circumference (WC),fasting plasma glucose (FPG),HbA1C,blood lipids,fasting serum insulin (FINS) were assayed or measured in all subjects.Results Plasma visfatin levels in T2DM with carotid atherosclerosis were significantly higher than those in normal control group and T2DM group [ (50.85 ± 20.14) ng/ml vs (18.50 ± 4.60) ng/ml,(50.85 ±20.14) ng/ml vs (35.52 ± 10.18) ng/ml,F = 105.983,P ＜0.01].Correlation analysis showed that plasma levels of visfatin were positively correlated with carotid IMT(r =0.476,P ＜0.01),TG (r =0.328,P ＜0.01),WC (r =0.206,P ＜0.05) and it was negatively correlated with HDL-C(r=-0.298,P ＜0.01).Conclusion Plasma visfatin was correlated with the development of macrovascular complications in T2DM patients,and it might be involved in the atherosclerotic pathological and physiological basis.

Objective:To investigate the thoughts and the methods of clinical pharmacists in the individual continuous renal re-placement therapy ( CRRT) anticoagulation treatment for severe patients. Methods:Clinical pharmacists participated in the CRRT anti-coagulation treatment for one patient with severe thrombocytopenia after aortic dissection surgery. Clinical pharmacists analyzed the cau-ses of thrombocytopenia and the coagulation function of the patient to exclude heparin-induced thrombocytopenia, and developed the treatment of supplementing platelets and regional citrate anticoagulation as the way of CRRT. Results:Three days after the treatment, the patient was changed to the general ward with normal renal function. Conclusion:Clinical pharmacists should participate in clinical treatment comprehensively and perform individual treatment for patients in order to ensure the effect and safety of medication.