1.Moderating effect of self-differentiation in relationship between life events and coping styles in college freshmen
Juan CAO ; Qin AN ; Yanqing DAI
Chinese Mental Health Journal 2015;(11):864-867
Objective:To explore the moderating effect of self-differentiation between life events and coping styles. Methods:Totally 584 college freshmen from Beijing and Jiangsu were selected to fill in the Adolescent Self-Rating Life Events Check-list (ASLEC),Differentiation of Self Inventory(DSI)and Simplified Coping Style Ques-tionnaire (SCSQ). Results:Self-differentiation had a moderating effect between life events and coping styles. The predicting effect of life events on negative coping was 0. 03 in the higher self-differentiation group (P>0. 05 ) while in the lower self-differentiation group,it was 0. 27 (P<0. 00 1 ). Conclusion:It suggests that higher self-differ-entiation could relieve the negative effect of life events to coping styles.
2. Serotonin, its receptors and depression
Journal of International Pharmaceutical Research 2012;39(5):409-413
Depression is an affective disorder with high prevalence. high suicide rate and low treatment rate. its neurobiologi-cal mechanism remains unclear. Most of current first-line antidepressants are based on the "monoamine hypothesis", including monoamine reuptake inhibitors, monoamine oxidase inhibitors and monoamine receptor ligand drugs. Although their therapeutic effect is definite, there are still serious defects. such as low response and delayed onset. It has been widely confirmed that depression is closely related to low serotonin (5-hydroxytryptamine, 5-HT) neurotransmission function (classical monoamine hypothesis), while modern monoamine theory suggests that the adaptability and plasticity regulation of 5-HT and its autoreceptors (such as 5-HT1A) are closely related to the treatment of depression. There are a series of new progress in recent years in the studies of 5-HT transporter proteins and 5-HT receptors, such as the positive role of S allele of the 5-HT transporter chain area in emotion and cognition, and the discoveries of the pharmacological basement of some new 5-HT-related receptor antagonists or agonists. There are also important breakthroughs in sero-tonineigic drug research and development (such as vilazodone, which approved by the US FDA in 2011, is a dual-target drug of 5-HT1A partial agonist and 5-HT reuptake inhibitor). In this review, the recent research progress on the relationship of 5-HT neuromodulation and depression is summarized. © 2006 Editorial office of Foreign Medical Sciences.
3.Blood Lead Levels of Children in Rural Areas of China
Juan QIN ; Mingyu DING ; Jinliang ZHANG
Journal of Environment and Health 2007;0(12):-
Objective To evaluate Chinese rural children's blood lead levels (BLLs) and identify its distribution features and to provide data for policy development to the prevention of rural environmental lead pollution. Methods The papers on rural children's BLLs published from 1994 to Oct, 2008 were collected by using CNKI's (China National Knowledge Infrastructure) Chinese Journal Full-test Database and other ways. The papers which were eligible for the following criteria were reviewed:(1) BLLs measured by atomic absorption spectroscopy (graphite or others) or inductively coupled plasma-mass spectrometry; (2) strict quality control; (3) no local lead pollution sources in the areas where the screened subjects live in; (4) children aged from 0 to 14 years old; (5)sample size more than 40. Results Analysis on the included 32 papers indicated that, the mean BLLs of Chinese rural children between 1994 and 2008 was 74.93 ?g/L ( range:41.14-193.54 ?g/L)and 19.32%( range:2.2%-43%) of the subjects had BLLs higher than 100 ?g/L. The rural children’s BLLs changed from 87.53 ?g/L to 71.16 ?g/L after the use of lead free gasoline in 2000 in China, which were both lower than the general children's BBLs before 2000 and after 2001. The children in Beijing city and Shandong province showed the highest mean BLLs , with 99.16 ?g/L and 92.13 ?g/L respectively; while the children in Jilin province and Hebei province showed the lowest levels, with 41.14 ?g/L and 56.14 ?g/L respectively. The comprehensive analysis of 18 papers indicated that the mean BLLs in rural areas and urban areas were 77.90 ?g/L and 87.24 ?g/L respectively ( u=3.73, P
4.The clinical evaluation of the effect of two different apical surgery timing
Juan LIN ; Chang'ao XUE ; Qin CAI
Journal of Practical Stomatology 2016;32(6):791-795
Objective:To observe the effect of two different apical surgery timing. Methods:68 patients with periapical lesion were divided into 2 groups. 30 patients( control group) were operated by apical surgery at least 1-2 months after root canal therapy( RCT) , while 38 patients(experimental group) were operated immediately after RCT. The patients were followed up 3, 6 and 12 months after apical surgery. Results:The curative effect analysed with the age, sex and tooth position showed no statistical difference between 2 groups(P>0. 05). Conclusion:Immediate and delayed apical surgery apical surger after RCT are similarly effective.
6.Analysis on evaluation tool for literature quality in clinical study.
Qing LIU ; Wei ZHAI ; Ya-qin TAN ; Juan HUANG
Chinese Acupuncture & Moxibustion 2014;34(9):919-922
The tools used for the literature quality evaluation are introduced. The common evaluation tools that are publicly and extensively used for the evaluation of clinical trial literature quality in the world are analyzed, including Jadad scale, Consolidated Standards of Reporting Trials (CONSORT) statement and Grades of Recommendations Assessment, Development and Evaluation (GRADE) system and the others. Additionally, the present development, updates and applications of these tools are involved in analysis.
Biomedical Research
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standards
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Evaluation Studies as Topic
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Humans
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Publications
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standards
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Quality Control
7.Change of activity of serum paraoxonase in patients with acute organophosphorus poisoning.
Juan-wen ZHANG ; Guo-cai LV ; Yu-qin JIN
Chinese Journal of Industrial Hygiene and Occupational Diseases 2007;25(10):610-611
Acute Disease
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Adult
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Aged
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Aryldialkylphosphatase
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blood
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Female
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Humans
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Male
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Middle Aged
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Organophosphate Poisoning
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Young Adult
10.Significance of determination of serum xanthine oxidase and lipid peroxidation indexes in acute organophosphorus poisoning.
Juan-wen ZHANG ; Guo-cai LV ; Yu-qin JIN
Chinese Journal of Industrial Hygiene and Occupational Diseases 2008;26(4):239-240
Acute Disease
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Adult
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Aged
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Female
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Humans
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Lipid Peroxidation
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Male
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Malondialdehyde
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blood
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Middle Aged
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Organophosphate Poisoning
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Oxidative Stress
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Superoxide Dismutase
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blood
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Xanthine Oxidase
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blood
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Young Adult