1.Difficult evaluation of thyroid cancer due to cervical paraffin injection.
Yong Sang LEE ; Eun Ju SON ; Bup Woo KIM ; Hang Seok CHANG ; Cheong Soo PARK
Journal of the Korean Surgical Society 2011;81(Suppl 1):S17-S20
Paraffinoma is a well known complication of previous paraffin injection into the subcutaneous layer that presents as various conditions including firm mass formation, edema, induration, ulceration, and skin necrosis. Paraffinoma can mimic neoplasm on physical examination and imaging studies and may complicate ultrasonographic diagnoses due to typical posterior shadowing and high echogenicity. When paraffinomas involve around the thyroid gland, the diagnosis of thyroid tumors is very difficult. We present a case of thyroid cancer, the evaluation of which was complicated by the presence of cervical paraffinoma.
Edema
;
Hydrazines
;
Necrosis
;
Paraffin
;
Physical Examination
;
Shadowing (Histology)
;
Skin
;
Thyroid Gland
;
Thyroid Neoplasms
;
Ulcer
2.A clinical study on the thyroid nodule in childhood.
Yong Ju KIM ; Ki Young CHEONG ; Jong Jin SEO ; Young Hun CHUNG
Journal of the Korean Pediatric Society 1991;34(8):1116-1122
No abstract available.
Thyroid Gland*
;
Thyroid Nodule*
3.Seroepidemiologic survey of residents and urban rats against the etiologic agents of hemorrhagic fever with renal syndrome in Singapore.
Ho Wang LEE ; Sang Youl LYU ; Lack Ju BAEK ; Yong Kyu CHU ; Wong Tae WAI ; Chan Yew CHEONG
Journal of the Korean Society of Virology 1991;21(1):77-85
No abstract available.
Animals
;
Hemorrhagic Fever with Renal Syndrome*
;
Rats*
;
Singapore*
4.Two cases of Gaucher disease in brother and sister.
Yong Ju KIM ; Ki Young CHEONG ; Jong Jin SEO ; Keon Su RHEE ; Young Hun CHUNG ; Seon Hoe KOO
Journal of the Korean Pediatric Society 1991;34(8):1151-1156
No abstract available.
Anemia
;
Gaucher Disease*
;
Humans
;
Siblings*
;
Thrombocytopenia
5.Heart Disease Screening for Primary School Children.
Chang Yee HONG ; In Sil LEE ; Hee Ju KIM ; Jung Hwan CHOI ; Hae Il CHEONG ; Jung Yun CHOI ; Yong Soo YUN
Journal of the Korean Pediatric Society 1985;28(3):258-262
No abstract available.
Child*
;
Heart Diseases*
;
Heart*
;
Humans
;
Mass Screening*
6.Detection of Down Syndrome & Edward Syndrome in uncultured amniocytes using FISH ( Fluorescence In Situ Hybridization.
Shin Yong MOON ; Jin CHOI ; Do Yeong HWANG ; Young Min CHOI ; Eun Ju CHANG ; Kyung Soon CHEONG ; Ki Chul KIM ; Eung Gi MIN ; Jin Yong LEE
Korean Journal of Obstetrics and Gynecology 1998;41(11):2859-2863
FISH is suggested as a possible method to detect the numerical and structural abnormalities of chromosomes in interphase nucleus. We performed this study to discuss the clinical usefulness of FISH in uncultured amniocytes and to set up the cut-off value for further study. We collected amniotic fluid samples from patients whose chromosome studies were recommended due to screen positive for Down and Edword syndrome in triple marker test using maternal serum. The centromeric probe for chromosome 18 and the locus-specific probe for chromosome 21 were used and the results were compared to their karyotypes. We could find 2 cases of trisony 21 and 2 cases of trisony 18 and the other cases represented normal karyotypes. The accuracies were 91% for disomy 18, 89% for trisomy 18, 92% for disomy 21 and 88% for trisomy 21. Therefore FISH technique is a possible method to detect the chromosomal abnormalities in uncultured amniocytes and the use of locus-specific probe for chromosome 21 would be more useful for detecting the aneuploidy of chromosome 21 than 13/21 centromeric probe.
Amniotic Fluid
;
Aneuploidy
;
Chromosome Aberrations
;
Chromosomes, Human, Pair 18
;
Chromosomes, Human, Pair 21
;
Down Syndrome*
;
Female
;
Fluorescence*
;
Humans
;
In Situ Hybridization*
;
In Situ Hybridization, Fluorescence
;
Interphase
;
Karyotype
;
Trisomy
7.Focal Segmental Glomerulosclerosis in a Child with Prader-Willi Syndrome: A Case of Obesity-associated Focal Segmental Glomerulosclerosis.
Hee Yeon CHO ; Dae Lim CHUNG ; Ju Hyung KANG ; Il Soo HA ; Hae Il CHEONG ; Yong CHOI
Journal of the Korean Society of Pediatric Nephrology 2004;8(2):244-249
Obesity-associated focal segmental glomerulosclerosis(OB-FSGS) has been known to progress into advanced renal insufficiency, and its clinicopathological features include obesity, FSGS lesions with glomerulomegaly and, nephrotic-range proteinuria without edema. A 14- year old girl with Prader-Willi syndrome showed nephrotic-range proteinuria without hypoalbuminemia or edema. The renal biopsy revealed focal segmental glomerulosclerosis together with glomerular hypertrophy and an increased mesangial matrix. We report here a case of OB-FSGS as one of the renal problems of Prader-Willi syndrome, and we came to the conclusion that Prader-Willi syndrome is one of the possible disease entities that can lead to renal insufficiency through obesity.
Biopsy
;
Child*
;
Edema
;
Female
;
Glomerulosclerosis, Focal Segmental*
;
Humans
;
Hypertrophy
;
Hypoalbuminemia
;
Obesity
;
Prader-Willi Syndrome*
;
Proteinuria
;
Renal Insufficiency
8.Characteristics and Recurrence Risk Factors of Urinary Tract Infection in Early Infancy.
Hee Gyung KANG ; Nam Hee KIM ; Ju Hyung KANG ; Il Soo HA ; Hae Il CHEONG ; Yong CHOI
Journal of the Korean Society of Pediatric Nephrology 2004;8(2):223-228
PURPOSE AND METHODS: Urinary tract infection(UTI) is one of the most important diseases of childhood, especially for young infants. To characterize the patients diagnosed with febrile UTI in their first 6 months of life and to explore the risk factors of recurrent UTI, a retrospective study was performed. RESULTS: Among the 90 patients studied, 77 were boys(86%). First episodes of UTI were diagnosed at the age of 2.5+/-1.4 months. These patients underwent ultrasonographic evaluation of urinary tract(n=90) and voiding cystourethrography(n=81) where 53 and 35 studies showed abnormal findings respectively, and a total of 45 cases of urinary tract anomaly including vesicoureteral reflux(VUR, n=35) were diagnosed. Normal findings on ultrasonography indicated decreased risk of VUR in boys of 1-3 months of age(n=30). 53 patients were followed up more than 6 months and 45 episodes of subsequent UTI developed in 29 patients during the first 6-month period. Patients with relapse were older than patients without relapse at the diagnosis of first UTI, but other clinical parameters including abnormal findings on the imaging studies and prophylactic antibiotics prescription were not different between the two groups. CONCLUSION: UTI in early infancy occurred mainly in male infants and half of the patients had structural anomalies. USG was of clinical value in detecting anomalies requiring surgical intervention, and to rule out high grade VUR in 1-3 months old boys. Results of the imaging study or prophylactic antibiotics could not modify the risk of recurrent UTI.
Anti-Bacterial Agents
;
Diagnosis
;
Humans
;
Infant
;
Male
;
Prescriptions
;
Recurrence*
;
Retrospective Studies
;
Risk Factors*
;
Ultrasonography
;
Urinary Tract Infections*
;
Urinary Tract*
9.A Clinicopathological Study of Rapidly Progressive Glomerulonephritis in Children.
Hee Yeon CHO ; Dae Lim CHUNG ; Ju Hyung KANG ; Il Soo HA ; Hae Il CHEONG ; Yong CHOI
Journal of the Korean Society of Pediatric Nephrology 2004;8(2):176-185
PURPOSE: Rapidly progressive glomerulonephritis (RPGN) is a clinicopathologic entity characterized by extensive crescent formation and rapid deterioration of renal function within few months. For better understanding of its clinical course and designing better treatment strategies, a clinicopathological study of childhood RPGN was performed. METHODS: The clinical manifestations and pathological findings were reviewed retro spectively in 12 children who were diagnosed as having RPGN by clinical manifestations and renal biopsy during a period from 1991 to 2003. Several clinicopathological parameters were analyzed as prognostic factors. RESULTS: Among a total of 12 patients, 4 were male and 8 were female. The median onset age was 11.5 years(range 5.5-14.6 years), and the median period of follow-up was 25 months(range 7 months-6.6 years). According to the pathological classification, 10 patients (83%) were type II RPGN(immune-complex mediated glomerulonephritis), 2 patients were type III RPGN(pauci-immune glomerulonephritis), and none was type I RPGN(anti-glome rular basement membrane nephritis). All patients were treated with oral steroid in various combinations with methylprednisolone pulse therapy(10 patients, 83%), cyclophosphamide(8 patients, 67%), or plasmapheresis(4 patients, 33%). Clinical outcomes of 12 patients were complete remission in 1(8%), end-stage renal disease in 2(17%), chronic renal insufficiency with persistent proteinuria in 2(17%), and normal renal function with persistent proteinuria in 7(58%) at the last follow-up. Poor prognosis is associated with increased serum creatinine level, severe anemia and younger age at the time of diagnosis. CONCLUSION: Immune-complex mediated glomerulonephritis is the major cause RPGN in children and most cases showed improvement of renal function with aggressive management. For better understanding of this rare disease, a prospective multicenter study should be done.
Age of Onset
;
Anemia
;
Basement Membrane
;
Biopsy
;
Child*
;
Classification
;
Creatinine
;
Diagnosis
;
Female
;
Follow-Up Studies
;
Glomerulonephritis*
;
Humans
;
Kidney Failure, Chronic
;
Male
;
Methylprednisolone
;
Prognosis
;
Proteinuria
;
Rare Diseases
;
Renal Insufficiency, Chronic
10.Chronic Arterial Occlusion by Hypercoagulable State 2 cases report (Antiphospholipid syndrome and Polycythemia vera).
Jeong Hwan CHANG ; Seong Hwan KIM ; Jong Hoon JEONG ; Cheong Yong KIM ; Young Don MIN
Journal of the Korean Society for Vascular Surgery 2001;17(1):120-125
Hypercoagulable states (HS) are well recognized as a cause of arterial and venous thromboembolism. These coditions are usually associated with abnormalities in natural anticoagulants, the fibrolytic system, or platelet aggregation. Primary arterial thrombosis is unusual in the young population. Hypercoagulable states are usually acquired, but they may be congenital. The congenital states occur in response to deficiency of protein C, protein S, AT-III. And the acquired states occur in response to disease, in response to tissue injury, or in response to therapy. But in this country, we have no any data of prevalence ratio of HS, which developed symptome of arterial occlusion, cases of bypass and theapeutic modality. We experienced two cases of acquired HS that is antiphospholipid syndrome and polycythemia. Based on our experience with this patients and a review of the literature on the previously reported. And we suggest that there will be made for the purpose of studying non-atherosclerotic lower extremity occlusion registry which developed in our country through the small study group.
Anticoagulants
;
Antiphospholipid Syndrome
;
Humans
;
Lower Extremity
;
Platelet Aggregation
;
Polycythemia*
;
Prevalence
;
Protein C
;
Protein S
;
Thrombosis
;
Venous Thromboembolism