No abstract available.
Child* ; Humans ; Urinary Tract Infections* ; Urinary Tract*

No abstract available.
Child* ; Eosinophils* ; Humans ; Immunoglobulin E* ; Skin Tests* ; Skin*

No abstract available.
Humans ; Twins*

The aim of this study was to analyze long-term survivals in patients with stage IB to IIA cervical cancer treated by neoadjuvant chemotherapy setting. Between February 1989 and January 1998, 94 women with previously untreated stage IB to IIA carcinoma of the uterine cervix who received cisplatin based neoadjuvant chemotherapy were enrolled in this study. All of patients with chemoresponse (complete response, n=15; partial response, n=47) and 16 patients with chemoresistance received radical surgery (RS group). The other 16 patients with chemoresistance received radiotherapy for definite treatment (RT group). In the RS group, the 10 yr survival estimation in patients with bulky tumors (diameter > or =4 cm, n=26) was similar to that with non-bulky tumors (83.3% vs. 89.3%, p=NS). In selected patients with chemoresistance, those treated by radiotherapy (n=16) showed significantly poorer survivals than those treated by radical surgery (n=16) [10 yr survival rates of RT (25%) vs. RS (76.4%), p=0.0111]. Our results support that a possible therapeutic benefit of neoadjuvant chemotherapy plus radical surgery is only in patients with bulky stage IB to IIA cervical cancer. In cases of chemoresistance, radical surgery might be a better definite treatment option.
Uterine Cervical Neoplasms/drug therapy/*radiotherapy/*surgery ; Treatment Outcome ; Survival Analysis ; Retrospective Studies ; Prognosis ; Neoplasm Staging ; Multivariate Analysis ; Middle Aged ; Humans ; Follow-Up Studies ; Fluorouracil/administration & dosage ; Female ; Drug Resistance, Neoplasm ; Combined Modality Therapy ; Cisplatin/administration & dosage ; Chemotherapy, Adjuvant ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Adult

Purpose: The aim of this qualitative study is to explore the health problems and coping experiences of middle-aged and elderly women in the community. Methods: A total of five focus group interviews were conducted with three groups of middle-aged and two groups of elderly women. All interviews were recorded and transcribed. Data were analyzed using the content analysis method. Results: Health problems were categorized as confusion caused by problems that are difficult to handle alone in the middle-aged group and suffering originated by confronting changes in roles and environment in the elderly group. The health problems included stress, suffering, anxiety and social withdrawal as subcategories for the middle-aged women, and the stress, sense of loss, fear, and limited social activities caused by their life events for the elderly women. Meanwhile, the contents of categories about coping were revealed as the beginning of care for the body and mind for healthy life in the middle-aged group and active practice with insight into a healthy lifestyle in the elderly group. While the middle-aged women focused on themselves, attempted changes and started to take care of themselves, the elderly women interacted with the outside world, hardened their mind, made efforts for a dignified death, and managed health by their own methods. Conclusion There were differences in the experiences of middle-aged and elderly women in accepting their health problems and coping. Nursing interventions reflecting these findings can help to manage and promote the health of middle-aged and elderly women based on an integrated perspective.

OBJECTIVES: Kienbock's disease, which is characterized by osteonecrosis of the lunate bone, causes progressive chronic pain and dysfunction of the hand and wrist. Even though occurrence of the disease was reported approximately 100 years ago and it is suspected to be work-related to some degree, the etiology has not been clearly discribed and the disease has rarely been considered as an occupation-related disease. As such, we submit this case as the first report of Kienbock's disease in Korea, with clinical findings, x-ray, MRI (magnetic resonance imaging) and strain index results along with a literature review. METHODS: The patient was carefully interviewed and her medical records were properly reviewed by the authors with her consent. The authors also visited her factory work site to inspect and videotape the working environment and to conduct an ergonomic evaluation with a strain index. RESULTS: Excessively repeated contact stress was found to be concentrated on her right hand and the environment was discovered to be hazardous from an ergonomic standpoint. The literature review revealed that heavy loads on the hand might be related to the cause or deterioration associated with Kienbock's disease. ; therefore, it is very likely that her disease is related to her work. CONCLUSIONS: There is much evidence to suggest that heavy workloads involving hand and wrist intensive tasks may cause and worsen Kienbock's disease. However, to date epidemiologic studies clarifying the etiology of the disease have not been sufficiently reported. Therefore, further research focusing on the etiology and prevention of the disease are required. In addition, practical guidelines for hand and wrist intensive tasks are needed to prevent disease development and worsening.
Chronic Pain ; Glycogen Storage Disease Type VI ; Hand ; Humans ; Korea ; Lunate Bone ; Medical Records ; Occupational Diseases ; Osteonecrosis ; Sprains and Strains ; Videotape Recording ; Workplace ; Wrist

Gastrointesinal polyp is a premalignant lesion, it is recommanded to be removed. Endoscopic polypectomy has long been considered as a safe and effective method for removal of polyps. One hundred forty eight endoscopic gastrointestinal polypectomy were done in 111 patients who visited Chungnam National University Hospital from January in l991 to August in l993, and clinical character including histopathology were evaluated. (continue...)
Chungcheongnam-do ; Humans ; Pathology ; Polyps

Arteriovenous malformations occur predominantly in the cecum and ascending colon and is not associated with vascular lesions of the skin, central nerveous system. or lung Arteriovenous malformations involving gastrointastinal tract is often to be found to be cause of the recurrent painless bleeding without specific past history and family history and usually diagnosed by selective mesenteric arteriography or colonoscopy, But because of small size of the lesion and local occurence, diagnosis of the arteriovenous malformation is very difficult. Authors exprienced a case of arteriovenous maltormation in the colon. The patient had a history of repeated gastrointestinal bleeding, and were diagnosed by colonoscopy and were treated with colonoscopic resection.
Angiography ; Arteriovenous Malformations* ; Cecum ; Colon* ; Colon, Ascending ; Colonoscopy ; Diagnosis ; Hemorrhage ; Humans ; Lung ; Skin

No abstract available.
Helicobacter pylori* ; Helicobacter* ; Peptic Ulcer* ; Prevalence* ; Stomach Neoplasms*

Tracheal intubation is accompanied by varying degrees of sympathetic stimulation as reflected by increases in heart rate and blood pressure. Several clinical trials to reduce the effects on blood pressure and heart rate by pharmacologic agents such as alpha and beta blockers, calcium channel blockers, narcotics and lidocaine, have been reported. To evaluate the effect of fentanyl and lidocaine on the hemodynamic changes induced by intubation, we administered thiopental 5 mg/kg only (group 1), fentanyl 3 ug/kg with thiopental 4 mg/kg (group 2) or fentanyl 3 ug/kg-lidocaine 1.5 mg/kg with thiopental 4 mg/kg (group 3) for induction of anesthesia, and measured heart rate, systolic pressure, diastolic pressure, mean pressure and rate- pressure products before induction, after induction and at 1, 3, 5, 7 and 10 minutes after intubation. 1) In group 1, intubation caused a significant increase in heart rate (27%), blood pressure (31%) and RPP (64%) at 1 min after intubation, but each paramenter returned to the normal level within 7 min. 2) In group 2, increases in heart rate, blood pressure and RPP with intubation were attenuated by fentanyl. 3) In group 3, the increase in heart rate induced by intubation was abolished by fentanyl-lidocaine, and the pressor effect was more attenuated compared to group 2. These results suggested that a low dose of fentanyl-lidocaine significantly blunts postintubation hypertension and tachycardia when used as an adjunt to thiopental.
Anesthesia ; Blood Pressure ; Calcium Channel Blockers ; Fentanyl* ; Heart Rate ; Hemodynamics* ; Hypertension ; Intubation* ; Lidocaine* ; Narcotics ; Tachycardia ; Thiopental