1.Simultaneous Elevation of Epidermal Growth Factor Receptor and Transforming Growth Factor - alpha in the Serum of Colorectal Cancer Patients.
Kang Sup SHIM ; Kwang Ho KIM ; Ju Young SEOH ; Eung Bum PARK
Journal of the Korean Cancer Association 1998;30(3):536-543
No abstract available.
Colorectal Neoplasms*
;
Epidermal Growth Factor*
;
Humans
;
Receptor, Epidermal Growth Factor*
2.A Case of Portal and Splenic Vein Thrombosis Developed by Complication of Histoacryl Injection Therapy in Gastric Varix.
Sung Won CHO ; Chan Sup SHIM ; Moon Sung LEE ; Jun Sung LEE ; Myung Lyel LEE ; Jae Hark JU
Korean Journal of Gastrointestinal Endoscopy 1994;14(4):437-441
Liquid tissue adheisve, Histoacryl (n-butyl-2-cyanoacrylate) has been used for the treatment of gastric variceal bleeding. The techniques are as follows: 0.5cc Histoacryl mixed with Lipiodol per each injection are used. 3 to 4 injections are usually required for large variceal convolutes under the fluoroscopic visualization after the injection of Histoacryl. Complications of sclerotherapy with Histoacryl are bleeding, perforation, stenosis and embolism depending on the concentration and amount used, as well as the intensity of the treatment. Here we describe a case report developing portal and splenic vein thrombosis as a side effect after Histoacryl injection therapy for the treatment of gastric varix bleeding, A 59-year-old male patient with liver cirrhosis was admitted due to acute gastric varix bleeding. The control of gastrie variceal bleeding was achieved by several injections of 0.7c mixture of 0.5cc histoacryl and 0,8cc Lipiodol. However, simple X-ray and ultrasonography revealed the elements of Histoacryl-lipiodol mixture in the portal and splenic vein.
Constriction, Pathologic
;
Embolism
;
Enbucrilate*
;
Esophageal and Gastric Varices*
;
Ethiodized Oil
;
Hemorrhage
;
Humans
;
Liver Cirrhosis
;
Male
;
Middle Aged
;
Sclerotherapy
;
Splenic Vein*
;
Thrombosis*
;
Ultrasonography
3.Clinical obsevation of pleural effusion.
Choon Sup KIM ; Kee Joong JU ; Chang Hwan LEE ; Sung Min PARK ; Young Woong SHIM ; Kap Young SONG
Tuberculosis and Respiratory Diseases 1993;40(5):584-594
No abstract available.
Pleural Effusion*
4.Tonsillar Squamous Cell Carcinoma Associated with Dermatomyositis: The First 2 Cases in Korea.
Sung Wan KIM ; Ju Sup SHIM ; Young Gyu EUN ; Kee Hwan KWON
Yonsei Medical Journal 2010;51(4):605-608
Dermatomyositis (DM) is an autoimmune disorder with idiopathic myopathy and characteristic skin manifestations that one often accompanied by an internal malignancy. The association between dermatomyositis and malignancy has been reported several times, although tonsillar carcinoma is extremely rare not only in far eastern populations but also in caucasian populations. We report two cases of Korean patients with dermatomyositis associated with tonsillar carcinoma.
5.A Case of Esophageal Perforation during Endoscopic Variceal Ligation.
Chan Sup SHIM ; Joon Seong LEE ; Moon Sung LEE ; Hong Soo KIM ; Chan Wook PARK ; Kwang Hwe LEE ; Hyung Joo PARK ; Sun Ju KIM
Korean Journal of Gastrointestinal Endoscopy 1995;15(2):223-233
Endoscopic variceal ligation(EVL) was developed to provide a safer alternative than injection sclerotherapy for treatment of bleeding esophageal varices. EVL adds a new indication that will significantly increase the use of overtubes. overtube itself may have a role in predisposing to esophageal perforation but only one report has been published regarding an esophageal perforation related to the placement of an overtube. Recently, we experienced a case of esophageal perforation caused by overtube placement during endoscopic variceal ligation. So we report this case with review of relevant literatures.
Esophageal and Gastric Varices
;
Esophageal Perforation*
;
Hemorrhage
;
Ligation*
;
Sclerotherapy
6.The Short Stature in Children with Hypertrophy of Adenoid and Tonsil or Allergic Rhinitis.
Ju Sup SHIM ; Sung Wan KIM ; Hee Seok CHOI ; Myung Gu KIM ; Joong Saeng CHO
Korean Journal of Otolaryngology - Head and Neck Surgery 2006;49(4):390-394
BACKGROUND AND OBJECTIVES: There is little data to indicate that hypertrophy of adenoid and tonsil may cause short stature. However, there is no data relating short stature to allergic rhinitis in the Korean population. The aim of this study was to investigate the effect of hypertrophy of adenoid and tonsil and allergic rhinitis on children with short stature. SUBJECTS AND METHOD: One hundred and ninety-one children were included in the disease group, which consisted of three groups, allergic rhinitis only (n=83), hypertrophy of adenoid and tonsil only (n=67), and combintorial of allergic rhinitis and hypertrophy of adenoid and tonsil (n=41). There were 174 pediatric patients in the control group. Growth hormone levels, thyroid function and both wrist X-rays were checked on the children with short stature in order to exclude other chief medical problems causing short stature. For the purpose of evaluating the relationship between short stature and clinical factors, allergy parameters, eosinophil partition rate and total IgE levels were checked in the allergic rhinitis group, and the size of the adenoid and tonsil were checked in the adenoid and tonsil hypertrophy group. The relationship between the incidence of short stature and above clinical factors was evaluated. RESULTS: The incidence of short stature was significantly higher in each disease group than in the control. However, there was no statistically significant differences between each disease group. The above clinical factors were not associated with short stature. CONCLUSION: Hypertrophy in adenoid and tonsil and allergic rhinitis might be an independent cause of short stature.
Adenoids*
;
Body Height
;
Child*
;
Eosinophils
;
Growth Hormone
;
Humans
;
Hypersensitivity
;
Hypertrophy*
;
Immunoglobulin E
;
Incidence
;
Palatine Tonsil*
;
Rhinitis*
;
Thyroid Gland
;
Wrist
7.A Case of Malignant Fibrous Histiocytoma on Nasal Dorsum.
Ju Sup SHIM ; Sung Wan KIM ; Chang Il CHA ; Joong Saeng CHO
Korean Journal of Otolaryngology - Head and Neck Surgery 2005;48(11):1398-1401
Soft tissue sarcoma of the head and neck is a rare and heterogenous group of malignant tumors. Especially, adult soft tissue sarcomas occur rarely in nasal cavity and paranasal sinus. They are, when poorly differentiated, termed as pleomorphic sarcoma, spindle cell sarcoma, or malignant fibrous histiocytoma (MFH) like tumor. The main stay of the treatment of adult soft tissue sarcomas is surgical resection with negative margin. Tumor grade, tumor size and extension of local infiltration are recognized prognostic factors, but classification of histologic type appears to have less prognostic significance. In case of uncontrolled locoregional disease, it often results in death due to intracranial extension. We report a case of a 68-year-old female with locoregional high grade pleomorphic sarcoma in the nasal cavity. This tumor was managed by wide local excision of tumor with negative margin.
Adult
;
Aged
;
Classification
;
Female
;
Head
;
Histiocytoma, Malignant Fibrous*
;
Humans
;
Nasal Cavity
;
Neck
;
Sarcoma
8.Sudden rapid growth of an aggressive angiomyxoma after taking pomegranate seeds oil.
Mi Kyoung KIM ; Eun Kyoung SHIN ; In Suk SHIM ; Sun Ok LEE ; Woong JU ; Seung Cheol KIM ; Sun Hee SUNG ; Woon Sup HAN
Korean Journal of Gynecologic Oncology 2007;18(1):58-61
Aggressive angiomyxoma (AA) is a rare soft tissue tumor of undetermined etiology that occurs mainly in the female vulva and perineum. It has been demonstrated to increase in size under the estrogenic stimulation and shown to respond to treatment with a GnRH agonist. A 47-year-old woman was presented with a large vulvar mass. The mass had grown slowly before she took pomegranate seeds oil on a regular basis for a year, which is known to contain natural estrogen for a year. The almond-sized mass enlarged into a fetal head-sized one in a year. Our case is implying that external administration of estrogenic substance may be a contributory factor to the sudden accelerated growth of AA. Although the past medical history in this case relies on an unverified observation by the patient alone, the unique clinical course and impressive gross appearance of AA may help clinicians with diagnosis in practice.
Diagnosis
;
Estrogens
;
Female
;
Gonadotropin-Releasing Hormone
;
Humans
;
Middle Aged
;
Myxoma*
;
Perineum
;
Punicaceae*
;
Vulva
;
Prunus dulcis
9.Three cases of extensive liver metastasis in neuroendocrine tumors.
Eui Ju PARK ; Seong Ran JEON ; Dae Yong KIM ; Jae Young JANG ; Jung Hoon KIM ; So Young JIN ; Chan Sup SHIM
Korean Journal of Medicine 2009;76(Suppl 1):S15-S21
Malignant neuroendocrine tumors have the histological features of malignant tumors, and localized invasion and distant metastasis can occur. After clinical presentation, patients with neuroendocrine tumors usually show rapid deterioration. The first case involved a patient who underwent treatment for poorly differentiated adenocarcinoma of the lung. A percutaneous liver biopsy was performed to look for diffuse infiltration of the tumor in the liver. As a result, the patient was diagnosed with large-cell neuroendocrine carcinoma of the lung with diffuse liver metastasis. The other two patients presented with liver masses. Liver biopsies revealed metastatic neuroendocrine tumors of the liver. In patients presenting with diffuse hepatic infiltration of a tumor, a neuroendocrine tumor should be considered in the diagnosis, and immunohistochemical staining and further studies should be performed to locate the origin of the tumor. We report three cases of neuroendocrine tumors with diffuse liver metastasis.
Adenocarcinoma
;
Biopsy
;
Carcinoma, Neuroendocrine
;
Humans
;
Liver
;
Lung
;
Neoplasm Metastasis
;
Neuroendocrine Tumors
10.A Randomized Prospective Trial Comparing a New Polyethylene Glycol Based Lavage Solution with the Standard Polyethylene Glycol Solution in the Preparation of Patients Undergoing Colonoscopy (Clinical trial of new PEG solution in bowel preparation).
Young Tae KIM ; Young Seok KIM ; Yong Ju PARK ; Su Jin HONG ; Jin Oh KIM ; Joo Young CHO ; Moon Sung LEE ; Chan Sup SHIM
Korean Journal of Gastrointestinal Endoscopy 2000;20(3):171-176
BACKGROUND/AIMS: Adequate preparation of the bowel is essential for accurate colonoscopic examination. Standard polyethylene glycol solution had been used as a bowel cleansing premedication. But many patients dislike the taste and saltiness of the polyethylene glycol solution. Comparison has made between colonic preparation with a new polyethylene glycol based solution that reduced the salt content and added flavoring in attempt to improve the palatability and to encourage patient compliance with the standard polyethylene glycol solution. METHODS: One hundred patients were randomized to receive either the new polyethylene glycol solution or the standard polyethylene glycol solution for their bowel cleansing preparation. Two gastroenterologists performing the colonoscopies were made unaware of the type of the preparation. The cleansing score and amount of residual fluids in each colonic segment was then evaluated. RESULTS: There was no significant difference in the colonic cleansing score and amount of residual fluids between two groups. Patients' compliance was higher for the new polyethylene glycol solution group than for the standard polyethylene glycol group. There was no difference in side effects of bowel cleansing solutions. CONCLUSION: The new polyethylene glycol solution as a bowel cleansing method has a higher patient compliance rate and is as effective as the standard polyethylene glycol solution.
Colon
;
Colonoscopy*
;
Compliance
;
Humans
;
Patient Compliance
;
Polyethylene Glycols*
;
Polyethylene*
;
Premedication
;
Prospective Studies*
;
Therapeutic Irrigation*