No abstract available.
Intestinal Atresia*

No abstract available.
Intestinal Atresia*

Modified Mohs surgery is a procedure which eliminated chemical fixation step from Mohs chemosurgery. This technique is faster, less painful and more tissue conserving, allows for immediste repairs, yields higher quality histologic preparations and facilitates an interdisciplinary apporoach; it is the treatment of choice for recurrent or difficult skin cancers. A 58-year-old femele patient presented with a 2x 3cm sized dark brownish, ulcerated nodule on the left upper eyelid. Histopathologic findings revealed several small solid nest composed of basalioma cells in the dermis. We treated with modified Mohs surgery and obtained good result.
Carcinoma, Basal Cell* ; Dermis ; Eyelids ; Humans ; Middle Aged ; Mohs Surgery* ; Skin Neoplasms ; Ulcer

No abstract available.
Rupture* ; Subclavian Artery*

We report a case of trichorrhexis nodosa in a 27-year-old male. Scanning electron microscopic findings reveals those of typical trichorrhexis nodosa nodal swelling of affected hair showed longitudinal fissures and fractures in the cortex. A paintbrush effect was noted at the site of fracture. Simple avoidance of trauma gave some regrowth of hairs.
Adult ; Hair ; Humans ; Male

The purpose of this study was to determine the proliferative activity of the osteoblasts and fibroblasts in the midpalatal area and to investigate the adjacent periodontal tissues of individual tooth following rapid expansion of the palate. Ten young adult dogs, aged approximately ten months, were used in the experiment. The experimental design was consisted of 1 week expansion group(Group E1, 3 dogs), 2 week expansion group(Group E2, 3 dogs), 2 week expansion and 2 week retention group(Group E3, dogs), and control group(Group C, 1 dog). For each group, expansion screw was activated one time per day(1/4 turn;90degrees) following Hyrax-screw application. The experimental animals in each group were sacrificed at 1, 2 and 4 weeks following palatal expansion. Maxillary tissue blocks wee obtained and prepared for the histomorphologic and immunohistochemical studies. Light microscope, polarizing microscope, and soft X-ray apparatus were used in this study, and following results were obtained. 1. In polarizing microscopic study, the expansion group(E1 & E2) showed blue color representing bone resorption and new bone formation in midpalatal suture area. E3 groups showed less color compared to the E1 and E2 group. But yellow color increased by calcification in the E3 groups. 2. Immunohistochemical study revealed that positive responses of the osteoblasts to PCNA and undifferentiated fibroblasts to EGF in E1 group were somewhat increased. Positive response to PCNA and EFG were increased in fibroblasts and the osteoblasts forming new bone in E2 group. In E3 group, the positive response cell concentrated the periphery of edge of palatal process in both PCNA and EGF. 3. Throughout the expansion period(E1 & E2), light microscopic study showed the edges of the extensive resorption new palatal processes, indication bone remodeling within the suture. E3 group exhibited less remodeling of midpalatal suture area. E2 group and E3 group showed cementum formation and resorption at the apex of 3rd premolar and 1st molar. E3 group exhibited extensive hyalinized zone on the cervical portion of buccal side of 1st molar. 4. Soft X-ray analysis of E1 group showed hypomineralized defect and microfractures in various parts of the suture areas when compared with control animals. There was no significant difference in the degree of mineralization in the midpalatal suture region between the C and E3 groups. Tooth axis showed tipping of 3rd premolar and 1st molar in the E2 group and E3 group. Based upon these experimental results, it is concluded that the undifferentiated mesenchymal cells always presented in midpalateal suture area following RPE. Differentiated osteoblasts and fibroblasts possess proliferating cellular activity until the 2 week retention period. The posterior teeth area tend to tip buccally as RPE force applied. Retention group exhibited irreversible response with severe hyalinized on the buccal surface of the first molar.
Animals ; Axis, Cervical Vertebra ; Bicuspid ; Bone Remodeling ; Bone Resorption ; Dental Cementum ; Dogs* ; Epidermal Growth Factor ; Fibroblasts ; Humans ; Hyalin ; Molar ; Osteoblasts ; Osteogenesis ; Palate ; Proliferating Cell Nuclear Antigen ; Research Design ; Sutures* ; Tooth* ; Young Adult*

Chondromalacia patella is a symptom complex characterized by aching pain behind the knee cap, retropatella tenderness that is aggravated by the stair climbing. Malalignment is an important factor causing chondromalacia patella. And to recognize it, is important in the diagnosis and treatment. We studied 3 parameters in the chondromalacic knee and nonchondromalacic knee and the following results was obtained. l. In nonchondromalacic knee, the sulcus angle is 141° 7′ and the congruence angle is −5° 1′ 2. In chonduomalacic knee the sulcus sagle is 139° 2′ and the congruence angle is +5° 3′ 3. In the group with abnormal congruence angle, there was much degenerative changes in the patellofemaral joint. So, it can be inferred that chondromalacia is a precursor of the osteoarthritis and the patient with abnormal congruence angle should be treated actively at the early stage if the conservative treatment had failed.
Cartilage Diseases ; Diagnosis ; Humans ; Joints ; Knee ; Osteoarthritis ; Patella ; Sesamoid Bones

PURPOSE: This study was designed to evaluate the safety and efficacy of early cessation of antibiotic treatment regardless of absolute neutrophil count in children with febrile neutropenia and no identifiable infectious source. METHODS: A prospective randomized clinical trial was performed in 93 episodes of fever in 37 neutropenic children with cancer, who were admitted to the Department of Pediatrics, Pusan National University Hospital from January 1996 to June 1997. RESULTS: Thirty-seven patients represented 93 febrile neutropenic episodes after chemotheraphy. Among them, 63 febrile episodes had no focus of fever, and there were 10 episodes of bacteremia. Of 63 febrile episodes who weren't identified focus of fever, only 47 febrile episodes had early cessation of antibiotics. During 47 febrile episodes, only 4 episodes (8.5%) had recurrent fever after early cessation of empirical antibiotic therapy. Between patients with recurrent fever and without recurrent fever, there were no significant difference in absolute neutrophil count (ANC) and CRP at admission, high body temperature before admission and duration of antibiotics. Recurrent rate of fever was high in patients who declined in absolute neutrophil count (ANC) and less than 25% increase in absolute phagocyte count (APC) at the stop of antibiotics. CONCLUSION: We suggest that early cessation of antibiotics regardless of absolute neutrophil count (ANC) is safe in the case of febrile neutropenia without an identifiable source of infection.
Anti-Bacterial Agents* ; Bacteremia ; Body Temperature ; Busan ; Child ; Febrile Neutropenia* ; Fever ; Humans ; Neutrophils ; Pediatrics ; Phagocytes ; Prospective Studies

Vitamin D deficiency and asthma are common public health problems worldwide. Recently, newer physiologic functions for vitamin D have been identified. Several studies suggest vitamin D plays a vital and complex role in immune system function and regulation. Asthma is one of the most common chronic diseases worldwide and has been increasing in prevalence over the last decades. Common risk factors for both asthma and vitamin D deficiency, such as an urbanized, westernized lifestyle and obesity have led to a hypothesized link between asthma and vitamin D. The purpose of this review is to present the evidence for a role of vitamin D in asthma.
Aluminum Hydroxide ; Asthma ; Carbonates ; Chronic Disease ; Hypersensitivity ; Immune System ; Life Style ; Obesity ; Prevalence ; Public Health ; Risk Factors ; Vitamin D ; Vitamin D Deficiency ; Vitamins

Scleroderma is a connective tissue disease characterized by excessive accumulation of collagen in skin and visceral organs due to increased collagen production by scleroderma fibroblasts. The basic etiology of this collagen accumulation is not known. We examined the expression of various extracellular matrix genes in cultured fibrolasts using Northern blot and slot-blot hybridization. The scleroderma fibroblasts exhibited characteristic mRNA size of extracellular matrix genes and prominanty increased type I and III procollagen mRNAs levels compared to control fibroblasts cultures from univolved skin. The ratios of type I /IE procollagen in scleroderma cell lines were not so much different to the controls. These results indicate that increases of collagen biosynthesis in scleroderma can be a accounted for, at least in part, by an increased content of transcriptable type I and type JE procollagen mRNAs, both.
Blotting, Northern ; Cell Line ; Collagen ; Connective Tissue Diseases ; Extracellular Matrix ; Fibroblasts* ; Procollagen ; RNA, Messenger ; Skin