Melanoacanthoma is an extremely rare pigmented benign mixed epithelial tumor of both melanocytes and keratinocytes. A 52-year-old female presented an asymptomatic, slightly elevated, 1. 2 cm x 0. 8 cm, dark black-colored plaque on her right buttock of 2 years' duration. Histopathologic finding of the plaque shows hyperkeratosis, focal parakeratosis, follicular plugging, acanthosih, papillomatosis and pseudo-horn cyst in the epidermis. The tumor is composed of basaloid and squarnous cells with many foci of clusters and whorls of melanin pigment-laden cells. Electron microscopic finding reveals many scattered melanocytes in the entire epidermis. Melanin granules are found mostly in the melanocytes but can also be found in a few keratinocytes.
Buttocks ; Epidermis ; Female ; Humans ; Keratinocytes ; Melanins ; Melanocytes ; Middle Aged ; Papilloma ; Parakeratosis

No abstract available.
Humans

No abstract available.
Humans

It is well known that involvement of the cranial nerves is a relatively common manifestation of tuberculous meningitis because tuberculous exudate is most likely to be located at the base of brain and in the basal cisterns. We reviewed 73 adult patients under the diagnosis of tuberculous meningitis at Hanyang University Hospital during last three and a half years from March, 1986. Patients were classified into two groups according to the presence or absence of cranial nerve palsies. Cranial nerve palsies were noted in 22 patients (30.1%) at the time of admission or in the early period of antituberculous therapy. The oculomotor and abdcens nerves were most commonly involved, followed by the optic nerve. In 10 cases with oculomotor nerve palsy, 7 cases were noted to have involvement of both pupils and extraocular movements, 2 had involvement of one pupil only and one remaining case involved extraocular movements only (spared pupil). Cranial nerve palsies developed 7 to 89 days (median, 21.5) after initial symptoms, and in 10 cases their palsies disappeared within 15 to 65 days (median, 40.9). The incidence of SIADH and basal meningeal involvement were much higher in the cranial nerve palsy group. Increase of total protein and decrease of sugar in initial CSF examination were significant (p<0.05) in the cranial nerve palsy group.
Adult* ; Brain ; Cranial Nerve Diseases* ; Cranial Nerves* ; Diagnosis ; Exudates and Transudates ; Humans ; Inappropriate ADH Syndrome ; Incidence ; Oculomotor Nerve Diseases ; Optic Nerve ; Paralysis ; Pupil ; Tuberculosis, Meningeal*

Isolated hydroceohalus is an uncommon entity wihch results from obstruction of the level of the foramen of Monnro. We have recently expierience three cases of isolated loculations of the lateral ventricle cause by intraventricular hemorrhage and ventriculitis. All patients were treated sucessfully using one or multiple shunts.
Hemorrhage ; Humans ; Lateral Ventricles*

Isolated hydroceohalus is an uncommon entity wihch results from obstruction of the level of the foramen of Monnro. We have recently expierience three cases of isolated loculations of the lateral ventricle cause by intraventricular hemorrhage and ventriculitis. All patients were treated sucessfully using one or multiple shunts.
Hemorrhage ; Humans ; Lateral Ventricles*

No abstract available.
Heart* ; Tomography, Emission-Computed, Single-Photon*

Cholangiocarcinoma has been associated with various fibrocystic diseases of liver and biliary tract, but cholangiocarcinoma in polycystic liver disease (PLD) was extremely rare. It was reported that the prognosis of cholangiocarcinoma associated PLD was very poor and distant metastases were common. We report a rare case of intrahepatic cholangiocarcinoma associated with PLD in 58- year- old female who presented vague abdominal pain. She had also polycystic kidneys with normal renal function. MRI showed well demonstrated tumor with central scar and a adjacent large cyst in the left lobe of the liver. She underwent extended left lobectomy. On microscopic examination, the tumor was moderately differentiated cholangiocarcinoma having abundant fibrous stroma and necrosis and the adjacent cyst showed focal in situ carcinomatous changes in the lining epithelium.
Abdominal Pain ; Biliary Tract ; Cholangiocarcinoma* ; Cicatrix ; Epithelium ; Female ; Humans ; Liver Diseases* ; Liver* ; Magnetic Resonance Imaging ; Necrosis ; Neoplasm Metastasis ; Polycystic Kidney Diseases ; Prognosis ; Cholangiocarcinoma

Using the 3-D TOF technique of MR angiography, the main intracranial and extracranial vessels of 46 normal controls and 37 patients with ischemic stroke were evaluated. In controls 1 the visibility of internal carotid artery and vertebrobasilar artery was ninety-one percent, and that of the first division of the middle cerebral artery was ninety-four percent. In patient groups, compared with the contrast angiographic findings, the sensitivity of MR angiography in detecting vascular occlusive lesions was 100.0% in anterior circulations, and 80.0% in posterior circulations. But several false positive cases were detected. Which were mainly associated with tortous tuming points of the vessels, and MIP artifacts. In spite of the high sensitivity of MR angiography in detecting vascular abnormalities, the degree of occlusive vascular lesions were more accentuated in MR angiography probably due to MIP artifact. The overestimated rate of vascular stenosis was about 24.6 percent compared with the contrast angiography.
Angiography* ; Arteries ; Artifacts ; Carotid Artery, Internal ; Constriction, Pathologic ; Humans ; Middle Cerebral Artery ; Stroke*

"Mirror-writing" is stript that runs in the direction opposite to normal with the individual letters also reversal. Several theories, including motor, visual dominance, spatial disorientation and supplementary motor hypotheses, have been proposed to explain "mirror-writng". With reviewing some of literatures, we present two cases of "mirror-writing" in association with bilateral basal ganglia hemorrhage and right frontal hematoma, respectively.
Basal Ganglia Hemorrhage ; Cerebral Hemorrhage* ; Hematoma ; Humans