Tarsal tunnel syndrom is characterized by pain, paresthesias in the foot in either the entire distribution of the tibial nerve or the distribution of one or two of its major branches and caused by compression of the posterior tibial nerve as it passes posterior and inferior to the medial malleolus. This syndrome is not recognized as readily as its counterpart in the upper extremity, the carpal tunnel syndrome. Anatomically unlike the transv erse carpal ligament the laciniate ligament(flexor retinaculum) has several deep fibrous septa which blend with the periosteum covering the medial side of the calcaneus. The neurovascular bundle in the tarsal tunnel is often attached to some of these septa, rendering itself more liable to minor degrees of traction on movements of the foot. A case of tarsal tunnel syndrome, the patient 24 years old policeman, treated succesfully with surgical release of laciniate ligament is reported.
Calcaneus ; Carpal Tunnel Syndrome ; Foot ; Humans ; Ligaments ; Paresthesia ; Periosteum ; Tarsal Tunnel Syndrome ; Tibial Nerve ; Traction ; Upper Extremity

PURPOSE: Human nucleus pulposus cells from intervertebral disc specimens were cultured to study the effects of TNF-alphaand IL-8 on the FAK expression by these cells. The effect of co-stimulation with dexamethasone on the FAK expression by nucleus pulposus cells was also studied. MATERIALS AND METHODS: The FAK expression in cultured human nucleus pulposus cells relation to TNF-alpha, IL-8 and dexamethasone was assessed by performing western blot. RESULTS: The activated FAK expression was up-regulated by treatments of TNF-alpha and IL-8. Dexamethasone attenuated the cytokine-induced FAK expression. The effects of inflammatory cytokines on the FAK expression were found to be concentration dependent with greater correlation shown by IL-8 than by TNF-alpha. CONCLUSION: The FAK expression of human nucleus pulposus cells was up-regulated by TNF-alpha and IL-8 stimulation and it was attenuated by the co-administration of dexamethasone.
Blotting, Western ; Cytokines ; Dexamethasone* ; Focal Adhesion Protein-Tyrosine Kinases ; Humans* ; Interleukin-8 ; Intervertebral Disc ; Tumor Necrosis Factor-alpha*

MR images of seven patients with histologically documented synovial sarcoma were reviewed to find the suggestive or pathognomonic findings of the disease. MR appearance of the tumor was inhomogeneous, multiseptated mass with various degree of internal septation and infiltrative tumor margin. The signal intensity of the mass was slightly hyperintense relative to muscle on T1-weighted image and hyperintense relative to subcutaneous fatty tissue on T2-weighted image.
Adipose Tissue ; Humans ; Magnetic Resonance Imaging* ; Sarcoma, Synovial*

No abstract available.

No abstract available.
Humans ; Pericardial Effusion* ; Rheumatic Fever*

Neuroblastoma occurs most frequently in children. It, however, may occur in adults. The peripheral neuroblastoma in adult is a primitive neuroectodermal tumor arising from peripheral tumor arising from peripheral nerve. It is exceedingly rare and estimated less than 1% of all malig-peripheral nerve tumors. We report a case of adult peripheral neuroblastoma arising in left lower extremity, who was treated with local excision and radiation.
Adult ; Child ; Humans ; Lower Extremity ; Neuroblastoma ; Neuroectodermal Tumors, Primitive ; Peripheral Nerves

Vibrio vulnificus causes very severe infections. The organism is isolated, for the most part, from the blood, and skin lesions. Isolation from other sources, including the urine, is very rate. Four cases of V. vulnificus septicemia were bacteriologically diagnosed in 1984 and 1985 at Severance Hospital. All of the patients were men, 42 years and older, with preexisting liver disease. All of them showed hypotension and secondary skin lesions, and all expired. The organism was isolated from the blood in all patients, from the peritoneal fluid in one, and from skin lesions in two. From one patient, isolation from a urine speAmen was also accomplished. All of the isolates were typical in their characteristics such as in their forming green colonies on Thiosulfate citrate bile sucrose (TCBS) agar, delayed acid production from lactose, and growth in broth with 6% NaCl.
Adult ; Human ; Middle Age ; Septicemia/diagnosis* ; Vibrio/isolation & purification ; Vibrio Infections/diagnosis*

Multidrug-resistant tuberculosis, resistant to at least isoniazid and rifampicin, continues to present a serious challenge to human health. However, there are no reports addressing multidrug-resistant tuberculous spondylitis in Korea. We report a case of multidrug-resistant tuberculous spondylitis at L2-L3 in a 30-year-old woman.
Adult ; Drug Resistance, Multiple ; Humans ; Isoniazid ; Korea ; Rifampin ; Spondylitis ; Tuberculosis ; Tuberculosis, Multidrug-Resistant

PURPOSE: To evaluate the accompanying abnormal findings of Schmorl's nodes(SN), a normal variants of thelumbar spine. MATERIALS AND METHODS: Seventy-five patients with one or more SN, as seen on lumbar spine MRI werestudied. Using a 1.5T MR unit, the number and location of SN, their site of the end plate, adjacent disc changesand lesion associated and not associated with SN, and accompanying associated bony spinal stenosis wereretrospectively investigated. RESULTS: Among the 75 patients, 230 SN were noted in 375 vertebral bodies; theywere relatively frequently located on the second(65, 28.2%) and third(65, 28.2%) lumbar vertebrae. The most commonend-plate site of SN was the posterior one-third portion(160;69.6%). In 450 discs of these 75 patients, 172lesions were noted;those associated with SN(76/167, 45.5%) was more common than those not thus associated (96/283,33.9%)(p <0.05), and those associated with SN were relative frequently located on intervertebral disc L2-3 orL3-4(p <0.05). Thirty-seven SN (16.1%) were associated with bony spinal stenosis. CONCLUSION: Because it isfrequently associated with disc lesions and bony spinal stenosis, SN of the lumbar spine may be a pathologiccondition rather than a normal variant.
Humans ; Intervertebral Disc ; Lumbar Vertebrae ; Magnetic Resonance Imaging ; Spinal Stenosis ; Spine*

The aim of this study was to investigate behavioral and psychological symptoms of dementia (BPSD) measured by caregiver-administered neuropsychiatric inventory (CGA-NPI) as a function of dementia severity in early onset (EOAD) versus late onset Alzheimer's disease (LOAD). A total of 113 patients with AD consisting of 49 patients with EOAD and 64 patients with LOAD were enrolled consecutively. General cognitive function and severity of dementia were assessed by the Korean version of mini-mental status examination and clinical dementia rating (CDR), respectively. In the mild stage (CDR 0.5-1), LOAD patients had a significantly higher total CGA-NPI score than EOAD patients. Subgroup analysis demonstrated that disinhibition and night-time behavior were more common and severe in the LOAD group than the EOAD group. However, in the moderate to severe stage (CDR 2-3), EOAD patients had a significantly higher total CGA-NPI score with higher subscores in hallucination, agitation/aggression, irritability/lability, aberrant motor behavior, and appetite/eating change. This study suggested that the heterogeneity of BPSD in AD might be accounted for by dementia severity as well as age at symptoms onset.
Alzheimer Disease* ; Dementia* ; Hallucinations ; Humans ; Population Characteristics