No abstract available.
Adrenal Hyperplasia, Congenital* ; Salts*

The development of the microvascular surgery revolutionalized the reconstructive surgery of the lower ext tremity. Especially, the defects of the heel and sole, the weight bearing area, were quite difficult and complicate to reconstruct by conventional methods. Many papers reported successful resurfacing the heel pad by free cutaneous or myocutaneous flaps. However, only few reports were conceming the late results of the reconstructed free flaps. The authors studied the histological and histochemical changes of the free flaps under the weight bearing stress in 10 cases. 1. The authors reconstructed 10 cases of the heel pad defects by dorsalis pedis free Aaps (5 cases) and latissimus dorsi myocutaneous flaps(5 cases). 2. Before transfer, the homy layer was very thin(about 0.16–0.2 mm) and had an arrangement of basket-weave pattem in both flaps. Until one year after transfer, this layer was wom out (0.02–0.08mm) However, after one year, this layer became thick (0.05–0.7 mm) and the arrangement was compact in both free flaps. 3. The granular and prickle cell layers were also increased in thickness after one year. 4. In the suprabasilar area, friction blisters were observed before one year, especially in latissimus dorsi myocutaneous flap. However, they slowly disappeared after one year and then the epidermis was stabilized. 5. In the dermis, the contents of the amyloid and acid mucopolysaccharides were increased up to the level of those of the normal heel pad in both flaps. 6. As a conclusion, the transferred free flaps were in distress before one year. But after one year, they began to adapt well histologically and histochemically to the weight bearing stress.
Amyloid ; Blister ; Dermis ; Epidermis ; Follow-Up Studies ; Free Tissue Flaps ; Friction ; Glycosaminoglycans ; Heel ; Myocutaneous Flap ; Superficial Back Muscles ; Weight-Bearing

Forty one cases of Hodgkin's disease and non-Hodgkin's lymphomas were immunohisto-chemi-cally studied for the presence of CD30 antigen on the paraffin embedded formaldehyde fixed tissue by using Ber H2(CD30) monoclonal antibody (Dakopatts, diluted l : 20) and avidin biotin peroxidase complex technique seventy five %(6/8) of Hodgkin's lymphoma and 27% (9/33) of non-Hodgkin's lymphomas were CD30 positive. Five of l7 diffuse large cell and immunoblastic lymphoma and one large cell anaplastic lymphoma showed large numbers of CD30 positive cells. Occasional CD30 positive cells were found in one of 2 angiommunoblastic lymphadenopathy-like T cell lymphoma, one of 4 small lymphocytic lymphoma and one unclassified lymphoma. Immunophenotypically l6% of B cell lymphoma and 42% of T cell lymphoma showed CD30 positivity. six cases of Hodgkin's disease except lymphocyte predominance showed positive tumor cells. Our results show that CD30 is more widespread in histologic subtypes of lymphomas and is not specific for the diagnosis of Hodgkin's disease.

Heavy metals, which are persistent in the environment and toxic, can accumulate in the body and cause organ damage, which may further negatively affect perinatal women and their fetuses. Therefore, this systematic review was conducted to evaluate the effectiveness of dietary interventions to reduce heavy metal exposure in antepartum and postpartum women. Methods: We searched five databases (PubMed, Embase, Scopus, Web of Science, and Cochrane Library) for randomized controlled trials that provided dietary interventions for antepartum and postpartum women. Quality assessments were conducted independently by two reviewers using the Cochrane Risk-of-Bias tool, a quality assessment tool for randomized controlled trials. Results: A total of seven studies were included. The studies were conducted in six countries, with interventions categorized into “nutritional supplements,” “food supply,” and “educational” strategies. Interventions involving nutritional supplements, such as calcium and probiotics, primarily reduced heavy metal levels in the blood and minimized toxicity. Food-based interventions, including specific fruit consumption, decreased heavy metal concentrations in breast milk. Educational interventions effectively promoted behavioral changes, such as adopting diets low in mercury. The studies demonstrated a low overall risk of bias, supporting the reliability of the findings. These strategies underscore the effectiveness of dietary approaches in mitigating heavy metal exposure and improving maternal and child health. Conclusion: The main findings underscore the importance of dietary interventions in reducing heavy metal exposure. This emphasizes the critical role of nursing in guiding dietary strategies to minimize exposure risks, ultimately supporting maternal and fetal health during pregnancy.

Heavy metals, which are persistent in the environment and toxic, can accumulate in the body and cause organ damage, which may further negatively affect perinatal women and their fetuses. Therefore, this systematic review was conducted to evaluate the effectiveness of dietary interventions to reduce heavy metal exposure in antepartum and postpartum women. Methods: We searched five databases (PubMed, Embase, Scopus, Web of Science, and Cochrane Library) for randomized controlled trials that provided dietary interventions for antepartum and postpartum women. Quality assessments were conducted independently by two reviewers using the Cochrane Risk-of-Bias tool, a quality assessment tool for randomized controlled trials. Results: A total of seven studies were included. The studies were conducted in six countries, with interventions categorized into “nutritional supplements,” “food supply,” and “educational” strategies. Interventions involving nutritional supplements, such as calcium and probiotics, primarily reduced heavy metal levels in the blood and minimized toxicity. Food-based interventions, including specific fruit consumption, decreased heavy metal concentrations in breast milk. Educational interventions effectively promoted behavioral changes, such as adopting diets low in mercury. The studies demonstrated a low overall risk of bias, supporting the reliability of the findings. These strategies underscore the effectiveness of dietary approaches in mitigating heavy metal exposure and improving maternal and child health. Conclusion: The main findings underscore the importance of dietary interventions in reducing heavy metal exposure. This emphasizes the critical role of nursing in guiding dietary strategies to minimize exposure risks, ultimately supporting maternal and fetal health during pregnancy.

Heavy metals, which are persistent in the environment and toxic, can accumulate in the body and cause organ damage, which may further negatively affect perinatal women and their fetuses. Therefore, this systematic review was conducted to evaluate the effectiveness of dietary interventions to reduce heavy metal exposure in antepartum and postpartum women. Methods: We searched five databases (PubMed, Embase, Scopus, Web of Science, and Cochrane Library) for randomized controlled trials that provided dietary interventions for antepartum and postpartum women. Quality assessments were conducted independently by two reviewers using the Cochrane Risk-of-Bias tool, a quality assessment tool for randomized controlled trials. Results: A total of seven studies were included. The studies were conducted in six countries, with interventions categorized into “nutritional supplements,” “food supply,” and “educational” strategies. Interventions involving nutritional supplements, such as calcium and probiotics, primarily reduced heavy metal levels in the blood and minimized toxicity. Food-based interventions, including specific fruit consumption, decreased heavy metal concentrations in breast milk. Educational interventions effectively promoted behavioral changes, such as adopting diets low in mercury. The studies demonstrated a low overall risk of bias, supporting the reliability of the findings. These strategies underscore the effectiveness of dietary approaches in mitigating heavy metal exposure and improving maternal and child health. Conclusion: The main findings underscore the importance of dietary interventions in reducing heavy metal exposure. This emphasizes the critical role of nursing in guiding dietary strategies to minimize exposure risks, ultimately supporting maternal and fetal health during pregnancy.

Heavy metals, which are persistent in the environment and toxic, can accumulate in the body and cause organ damage, which may further negatively affect perinatal women and their fetuses. Therefore, this systematic review was conducted to evaluate the effectiveness of dietary interventions to reduce heavy metal exposure in antepartum and postpartum women. Methods: We searched five databases (PubMed, Embase, Scopus, Web of Science, and Cochrane Library) for randomized controlled trials that provided dietary interventions for antepartum and postpartum women. Quality assessments were conducted independently by two reviewers using the Cochrane Risk-of-Bias tool, a quality assessment tool for randomized controlled trials. Results: A total of seven studies were included. The studies were conducted in six countries, with interventions categorized into “nutritional supplements,” “food supply,” and “educational” strategies. Interventions involving nutritional supplements, such as calcium and probiotics, primarily reduced heavy metal levels in the blood and minimized toxicity. Food-based interventions, including specific fruit consumption, decreased heavy metal concentrations in breast milk. Educational interventions effectively promoted behavioral changes, such as adopting diets low in mercury. The studies demonstrated a low overall risk of bias, supporting the reliability of the findings. These strategies underscore the effectiveness of dietary approaches in mitigating heavy metal exposure and improving maternal and child health. Conclusion: The main findings underscore the importance of dietary interventions in reducing heavy metal exposure. This emphasizes the critical role of nursing in guiding dietary strategies to minimize exposure risks, ultimately supporting maternal and fetal health during pregnancy.

Heavy metals, which are persistent in the environment and toxic, can accumulate in the body and cause organ damage, which may further negatively affect perinatal women and their fetuses. Therefore, this systematic review was conducted to evaluate the effectiveness of dietary interventions to reduce heavy metal exposure in antepartum and postpartum women. Methods: We searched five databases (PubMed, Embase, Scopus, Web of Science, and Cochrane Library) for randomized controlled trials that provided dietary interventions for antepartum and postpartum women. Quality assessments were conducted independently by two reviewers using the Cochrane Risk-of-Bias tool, a quality assessment tool for randomized controlled trials. Results: A total of seven studies were included. The studies were conducted in six countries, with interventions categorized into “nutritional supplements,” “food supply,” and “educational” strategies. Interventions involving nutritional supplements, such as calcium and probiotics, primarily reduced heavy metal levels in the blood and minimized toxicity. Food-based interventions, including specific fruit consumption, decreased heavy metal concentrations in breast milk. Educational interventions effectively promoted behavioral changes, such as adopting diets low in mercury. The studies demonstrated a low overall risk of bias, supporting the reliability of the findings. These strategies underscore the effectiveness of dietary approaches in mitigating heavy metal exposure and improving maternal and child health. Conclusion: The main findings underscore the importance of dietary interventions in reducing heavy metal exposure. This emphasizes the critical role of nursing in guiding dietary strategies to minimize exposure risks, ultimately supporting maternal and fetal health during pregnancy.

Primary small cell carcinoma of the salivary gland is a rare neoplasm that accounts for approximately 1.8% of all primary major salivary gland malignancies. Because of its rarity, it is difficult to diagnose small cell carcinoma of the parotid gland by fine needle aspiration cytology(FNAC). We experienced a case of primary small cell carcinoma of the parotid gland in a 72-year-old woman who presented with two palpable masses of the left infraauricular and ocular regions of two to three month's duration, respectively. Aspirate smears from the left infraauricular area were highly cellular on necrotic and lymphocytic background and showed individually dispersed cells or three-dimensional clusters of small cells. The tumor cells were round to oval with a very high nucleocytoplasmic ratio. Nuclei were about two times the size of lymphocytes and had uniformly dispersed but hyperchromatic to pyknotic chromatin. Nucleoli were occasionally visible but were generally inconspicuous. Numerous mitotic figures were detected. The clusters of these small tumor cells exhibited angular nuclear molding, irregular nuclear outlines, and occasionally rosette like arrangement. The tumor was confirmed by histology and immunohistochemistry.
Aged ; Animals ; Benzodiazepines* ; Biopsy, Fine-Needle ; Carcinoma, Small Cell ; Chromatin ; Female ; Fungi ; Humans ; Immobilization* ; Immunohistochemistry ; Lymphocytes ; Parotid Gland ; Rats* ; Receptors, GABA-A* ; Salivary Glands ; Thyroid Gland

No abstract available.
Penicillamine*