PURPOSE: Spontaneous heterotopic pregnancy (HP) is a rare .condition, however, the rising incidence after in-vitro fertilization and embryo transfer (IVF-ET) may present serious problems as the diagnosis of this potentially fatal condition is often missed. The purposes of this study were to investigate the frequency of HP after IVF-ET, to analyze the clinical presentation and the outcome of coincidental intrauterine pregnancy, and to evaluate the value of routine transvaginal ultrasonography in early diagnosis and treatment of HP. MATERIALS AND METHODS: There were 11 cases of HP among 484 pregnancies after IVF-ET (The incidence was 2. 3%) in recent 2 years. We evaluated the clinical findings and the findings of transvaginal sonography in those 11 patients. RESULTS: The combined extrauterine pregnancies were tubal (n=9), cornual (n=l), and both the tubal and cornual (n=l). Vaginal bleeding was absent in 4 cases and one of them was asymptomatic. HP may be suspected if there was an elevated serum hCG in the absence of intrauterine multiple gestations. In all cases, the condition was diagnosed by transvaginal sonography performed prior to surgical intervention. The coincidental intr'auterine pregnancies were ended in successful full-term delivery in 7 cases, while one pregnancy was ongoing at that time. CONCLUSION: The incidence of HP was evidently higher in IVF-ET than in spontaneous pregnancies. Transvaginal sonography was useful in accurate diagnosis in clinically suspected cases and even in asymptomatic cases. Routine transvaginal sonography played an important role in early diagnosis and prompt management of HP.
Diagnosis ; Early Diagnosis ; Embryo Transfer ; Embryonic Structures* ; Fertilization ; Fertilization in Vitro* ; Humans ; Incidence ; Pregnancy ; Pregnancy, Heterotopic* ; Ultrasonography* ; Uterine Hemorrhage

Bleaching creams containing hydroquinone are modestly effective in treating some cutane ous pigmentary disorders. Hydroquinone creams frequently cause mild irritant reactions and postinflammatory hyperpigmentation, but rarely allergic reactions. A case of allergic contact dermatitis due to hydroquinone in a 21-year-old woman was confirmed by the patch test.
Dermatitis, Allergic Contact* ; Female ; Humans ; Hyperpigmentation ; Hypersensitivity ; Patch Tests ; Young Adult

Multiple trichoepithelioma is an uncommon skin disease with autosomal dominant transmission. A 21-year-old female ahd asymptomatic, flesh-colored, firm papules and nodules on the face, chest and back. Histopathologic examination showed multiple horn cysts and tumor islands composed of basaloid cells.
Animals ; Female ; Horns ; Humans ; Islands ; Skin Diseases ; Thorax ; Young Adult

Localized primary cuteneous nodular amyloidosis is the rarest form of the cutaneous amyloidosis, which appears as single or multiple nodules on the extremities, trunk, genitalia or face. A 44-Year-old woman had asymptomatic, translucent brown to pink papules and nodules on the toes for 5 years. Histopathologic exarnination showed deposition to pale, eosinophilic, amorphous material throughout the dermis, Under the electron microscope, the material consisted of straight, nonbranching, nonanastoimosing filaments. We thus made the diagnosis of nodular amyoidosis.
Adult ; Amyloidosis* ; Dermis ; Diagnosis ; Eosinophils ; Extremities ; Female ; Genitalia ; Humans ; Toes

PURPOSE: This study performed to identify the association between various nutritional indices including biochemical, anthropometric variables and mortality in Korean elderly. METHODS: Among a total of 151,000 subjects over 40 years of living in Jung-up district, 1051 was selected using a random cluster sample method. Between Dec 1996 and Feb 1997, they underwent the blood tests and anthropometric measurements. Three years later, on Dec 2000, we investigated the mortality of the 340 subjects that had been over 65 years at the enroll time. RESULTS: Of the 1051 subjects(M:F=410:641), 340 were over 65 years at the enroll time, 34(10%) had died by 3 years follow up. After adjustment of age and sex, decreased Hb, Hct, serum protein, albumin, increased serum creatinine were significantly associated with an increased risk of mortality(p<0.05) among the variables. Especially serum albumin remained strong predictors of mortality after cont rolling for other significant variables(RR=0.15, 95% CI=0.03-0.63, p=0.01). CONCLUSION: We confirmed the strong independent association with serum albumin and mortality in the rural community dwelling ambulatory elderly Koreans.
Aged* ; Creatinine ; Follow-Up Studies ; Hematologic Tests ; Humans ; Jeollabuk-do ; Mortality ; Nutrition Assessment ; Rural Population ; Serum Albumin

No abstract available.
Female ; Pregnancy ; Pregnancy, Ectopic*

We report a patient with a cutis laxa-like, generalized PXE without systemic involvement. A 28-year-old woman had loose, pendulous skin of the neck, axillae, thighs, trunk and body folds which resulted in a prematurely aged appearance. She had no family history of related diseases. Histological examination showed considerable accumulations of swollen and irregularly clumped fibers in the middle and lower dermis and von Kossa s stain revealed calcium deposits along the altered elastic fibers.
Adult ; Axilla ; Calcium ; Dermis ; Elastic Tissue ; Female ; Humans ; Neck ; Pseudoxanthoma Elasticum* ; Skin ; Thigh

We report a patient with a cutis laxa-like, generalized PXE without systemic involvement. A 28-year-old woman had loose, pendulous skin of the neck, axillae, thighs, trunk and body folds which resulted in a prematurely aged appearance. She had no family history of related diseases. Histological examination showed considerable accumulations of swollen and irregularly clumped fibers in the middle and lower dermis and von Kossa s stain revealed calcium deposits along the altered elastic fibers.
Adult ; Axilla ; Calcium ; Dermis ; Elastic Tissue ; Female ; Humans ; Neck ; Pseudoxanthoma Elasticum* ; Skin ; Thigh

No abstract available.
Anesthesia, Spinal* ; Cesarean Section* ; Female ; Humans ; Infant, Newborn* ; Pregnancy

OBJECTIVE: The purpose of this study was to assess the role of HPV 16 and 18 in adenocarcinoma in situ(ACIS) of the uterine cervix. METHODS: Seventeen cases of primary cervical adenocarcinoma in situ were analyzed for HPV DNA by polymerase chain reaction. HPV 16 and 18 DNA extracted from formalin-fixed, paraffin-embedded histologic tissue sections by polymerase chain reaction. RESULTS: 35.3% and 23.5% of ACIS were positive for HPV 16 and HPV 18 DNA, respectively. From the normal tissue, 11.8% were positive for HPV 16. Human papillomavirus positive patients were younger than negative patients but statistically insignificant(mean age 42.1 vs 51.7 years). CONCLUSIONS: These results show that HPV type 16 and 18 were closely related to etiology of the ACIS of the uterine cervix.
Adenocarcinoma* ; Cervix Uteri* ; DNA ; Female ; Human papillomavirus 16 ; Human papillomavirus 18 ; Humans* ; Papilloma* ; Polymerase Chain Reaction