2.Electromicroscopic Characterization about Vibrio alginolyticus Phage Isolated from Marine Products.
Jin Woo JU ; Seong A JU ; Moon Soo HEO ; So Gyem YOON ; Joo An OK ; Byoung Gon MOON
Journal of the Korean Society for Microbiology 1997;32(1):91-101
The study of bacteriophage began by F.W. Twort in 1915 and the lytic cycle recognized by d'Herellel in 1917. It repeated about the marine bacteriophage containing Vibrio phage by Smith, Spencer and Ju. Authors isolated 2 virulent phages for the pathogenic V. alginolyticus from marine products. These 2 phages were examined their ultrastructure & host-infection by elecron microscopy and in vivo test using skin of rats. V. alginolyticus phages(VAPs) fomed plaques about 0.5 - 0.9mm in diameter and bands 50 - 60% in sucrose density gradient. VAP had 50 - 120nm tail and 40 - 90nm head in diameter. In vivo test, using rat skin, as well as in vitro test VAP had the activity to V. alginolyticus isolated.
Animals
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Bacteriophages*
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Coriolaceae
;
Head
;
Microscopy
;
Rats
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Skin
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Sucrose
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Tail
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Vibrio alginolyticus*
;
Vibrio*
3.New compression dressing on the management of the otohematoma.
Young Ha KWON ; Ju Byoung SEONG ; Hyoung Keun CHA ; Back Am CHANG ; Soo Man PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(5):1062-1064
No abstract available.
Bandages*
5.Effects of Smoking on Tear Film and Ocular Surface.
Kyung Chul YOON ; Byoung Yong SONG ; Man Seong SEO
Korean Journal of Ophthalmology 2005;19(1):18-22
This study was performed to evaluate the changes of tear film and ocular surface caused by smoking. Symptom scoring, tear film break-up time (BUT), basal tear secretion test, corneal sensitivity test, keratoepitheliopathy scoring, and conjunctival impression cytology were performed in 29 smokers (58 eyes) and 26 non-smokers (52 eyes). Tear film BUT, basal tear secretion, corneal sensitivity, and squamous metaplasia were 7.71 +/- 2.66 sec, 6.29 +/- 2.85 mm, 53.69 +/- 5.69 mm, and 2.45 +/- 1.26 in smokers and 9.62 +/- 3.14 sec, 10.04 +/- 3.87 mm, 56.46 +/- 4.79 mm, and 1.12 +/- 0.83 in non-smokers, respectively (p< 0.05). Symptom score, keratoepitheliopathy score, and goblet cell density were not significantly different between the two groups. Tear film BUT was shorter, basal tear secretion and corneal sensitivity were lower, and squamous metaplasia was higher in heavy smokers than in light smokers. In conclusion, smoking deteriorates the tear film and ocular surface with decreased quantity and quality of tear film, decreased corneal sensitivity, and squamous metaplasia, and this deterioration is related to the amount of smoking.
Adult
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Aged
;
Cell Count
;
Conjunctiva/*metabolism/pathology
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Cornea/*metabolism/pathology
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Epithelial Cells/pathology
;
Goblet Cells/metabolism/pathology
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Humans
;
Lacrimal Apparatus/*metabolism/physiopathology
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Male
;
Metaplasia
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Middle Aged
;
Smoking/*metabolism/physiopathology
;
Tears/chemistry/*secretion
6.Acute Cerebral Artery Occlusion by Direct Tumor Embolus
Dong Kun LEE ; Min A LEE ; Byoung Wook HWANG ; Chang Ju LEE ; Sung-Chul LIM ; Sang Woo HA ; Seong Hwan AHN
Journal of the Korean Neurological Association 2021;39(1):30-33
In acute stroke, emboli are mostly composed of thrombi from artery, cardiac chamber, valve and vein. Non-thrombotic emboli are sometimes difficult to identify the origin. According to the increased number of cancer patients, now 10% of stroke patients have a cancer. However, the potential mechanisms of stroke in patients with cancer are various. We presented a case of serious acute arterial occlusion with a tumor embolus, which was revealed by histopathologic analysis of retrieved emboli during mechanical thrombectomy.
7.Asthma Prevention by Lactobacillus Rhamnosus in a Mouse Model is Associated With CD4+CD25+Foxp3+ T Cells.
Seong Ok JANG ; Ha Jung KIM ; Young Joon KIM ; Mi Jin KANG ; Ji Won KWON ; Ju Hee SEO ; Hyung Young KIM ; Byoung Ju KIM ; Jinho YU ; Soo Jong HONG
Allergy, Asthma & Immunology Research 2012;4(3):150-156
PURPOSE: Probiotic bacteria can induce immune regulation or immune tolerance in allergic diseases. The underlying mechanisms have been recently investigated, but are still unclear. The aim of this study was to evaluate the protective effects of the probiotic Lactobacillus rhamnosus (Lcr35) in a mouse model of asthma and to identify its mechanism of action. METHODS: Lcr35 was administered daily by the oral route at a dosage of 1x10(9) CFU/mouse in BALB/c mice for 7 days before the first sensitization. Clinical parameters and regulatory T (Treg) cells were examined. The role of CD4+CD25+Foxp3+ Treg cells was analyzed using a Treg cell-depleting anti-CD25 monoclonal antibody (mAb). RESULTS: Airway hyperresponsiveness, total IgE production, pulmonary eosinophilic inflammation, and splenic lymphocyte proliferation were suppressed after Lcr35 treatment. Th1 (IFN-gamma) and Th2 (IL-4, IL-5, and IL-13) cytokines in the serum were suppressed, and the percentage of CD4+CD25+Foxp3+ Treg cells in the spleen was significantly increased in the Lcr35 treatment group. Anti-CD25 mAb administration abolished the protective effects of Lcr35, indicating that CD4+ CD25+Foxp3+ Treg cells are essential in mediating the activity of Lcr35. CONCLUSIONS: Oral administration of Lcr35 attenuated the features of allergic asthma in a mouse model and induced immune regulation by a CD4+CD25+Foxp3+ Treg cell-mediated mechanism.
Administration, Oral
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Animals
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Asthma
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Bacteria
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Cytokines
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Eosinophils
;
Immune Tolerance
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Immunoglobulin E
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Inflammation
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Interleukin-5
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Lactobacillus
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Lactobacillus rhamnosus
;
Lymphocytes
;
Mice
;
Negotiating
;
Probiotics
;
Spleen
;
T-Lymphocytes
;
T-Lymphocytes, Regulatory
8.The Etiology of Acute Stroke with Experience of Repeated Upper Extremity Deep Vein Thrombosis
Chang Ju LEE ; Dong Kun LEE ; Min A LEE ; Byoung Wook HWANG ; Ju Hye KIM ; Hyeo Seo MOON ; Sung-Chul LIM ; Seong Hwan AHN
Journal of the Korean Neurological Association 2023;41(1):52-55
In stroke patients, upper extremity deep vein thrombosis (UEDVT) is uncommon compared with lower extremity. Unlike the blood stasis in lower extremity, UEDVT has been developed by secondary cause. We reported a case of stroke patient with repeated UEDVT, presenting superficial venous congestion, who was finally diagnosed with pulmonary adenocarcinoma. The cause of stroke was non-bacterial thromboembolism formed at the mitral valve. Our case shows that unexpected UEDVT should be closely evaluated for higher coagulable status such as a malignancy.
9.A Case of Desmoid Tumor Presenting as Intra-abdominal Abscess.
Yeon Hwa YU ; Byoung Kwan SON ; Dae Won JUN ; Seong Hwan KIM ; Yun Ju JO ; Young Sook PARK ; Boo Whan HONG ; Jong Eun JOO
The Korean Journal of Gastroenterology 2009;53(5):315-319
Desmoid tumor is a rare benign tumor derived from fibrous sheath or musculoaponeurotic structure. The tumor is benign histologically but considered as malignant clinically because it has high propensity on infiltrative growth with local invasion and tendency to recurrence after local excision. Especially, when this tumor happens to be in the intra-abdomen, the prognosis is worse because it can cause intestinal obstruction, ureter obstruction and, fistula formation. It also can invade major vessels in abdomen. This tumor occurs more frequently in patients with familial adenomatous polyposis (FAP), in post-partume women, and at old surgical incision site. However, in this case, the patient had neither previous surgery nor a FAP history. We report a rare case of the young male patient who presented with an acute abdomen and underwent laparotomy and was found to have an intra-abdominal desmoid tumor with abscess formation.
Abdominal Abscess/diagnosis
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Adult
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Diagnosis, Differential
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Fibromatosis, Abdominal/*diagnosis/pathology/surgery
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Humans
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Male
;
Peritoneal Neoplasms/*diagnosis/pathology/surgery
;
Tomography, X-Ray Computed
10.Intrapericardial Implantation of an Implantable Cardioverter-Defibrillator in a Child.
Yong Won SEONG ; Woong Han KIM ; Jae Suk YOO ; Hye seon KIM ; Byoung Ju MIN ; Young Ok LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 2011;44(1):61-63
Implantable cardioverter defibrillator (ICD) can be a crucial therapeutic modality for pediatric patients with congenital heart disease, Brugada syndrome, long QT syndrome and cardiomyopathy. Because transvenous implantation of ICD is mostly unfeasible for pediatric patients due to anatomical and technical limitations, epicardial patch type or subcutaneous type ICD have been used. Implantation of these alternative ICDs, however, was reported to be frequently associated with significant complications. We report a case of successful intrapericardial implantation of a single coil-type ICD through the transverse sinus in a 27 month-old child weighing lesser than 10 kg, and it was inferred from this experience that this alternative technique may decrease complications and morbidities after ICD implantation in children.
Arrhythmias, Cardiac
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Brugada Syndrome
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Cardiomyopathies
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Child
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Defibrillators
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Defibrillators, Implantable
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Heart Diseases
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Humans
;
Long QT Syndrome