Neutropenic enterocolitis is observed in approximately 10~46% of patients with acute leukemia, as well as in patients with other diseases, like acquired immunodeficiency syndrom (AIDS), that lead to profound neutropenia. Patients who become neutropenic after combined chemotherapy are at special risk of developing neutropenic enterocolitis. With the recently increasing numbers of patients with solid tumors treated with high-dose chemotherapy, the frequency of this disease is expected to increase. However, this disease has been rarely reported in patients with colon cancer treated with leucovorin and 5-fluorouracil for adjuvant chemotherapy. We report a case of neutropenic enterocolitis after a treatment of 5-fluorouracil and leucovorin for sigmoid colon cancer.
Chemotherapy, Adjuvant ; Colon* ; Colonic Neoplasms* ; Drug Therapy* ; Enterocolitis, Neutropenic* ; Fluorouracil ; Humans ; Leucovorin ; Leukemia ; Neutropenia ; Sigmoid Neoplasms

The incidence of an appendiceal diverticulum in instance of appendectomies has been reported to range from 0.004 to 2.1 percent. It is known that diverticulum of the appendix leads to diverticulitis, appendicitis, or perforation. Recently in the literature, appendiceal diverticulum without inflammation has been reported as a possible cause of chronic abdominal pain. We report the case of a 40-year-old man with appendiceal diverticula associated with chronic abdominal pain.
Abdominal Pain* ; Adult ; Appendectomy ; Appendicitis ; Appendix* ; Diverticulitis ; Diverticulum* ; Humans ; Incidence ; Inflammation

Enterobius vermicularis is one of the common parasites in the world. The infestation rate of Enterobius vermicularis is higher in children than in adults. Moreover, the egg-positive rate of Enterobius vermicularis is higher in the mentally retarded population. We report the case of a ten-year-old, mentally retarded boy, who was diagnosed as having acute appendicitis associated with Enterobius vermicularis.
Adult ; Appendicitis* ; Child ; Enterobius* ; Humans ; Male ; Mentally Disabled Persons ; Parasites

he conclusion should be corrected as The addition of aminoglycoside to dual antibiotic therapy, second cephalosporinmetronidazole showed no advantage in prevention of postoperative wound complications. Journal of The Korean Society of Coloproctology apologizes to the readers for this error.

Colorectal cancer is a disease developed by the accumulation of genomic alteration. Two genomic instability pathways, chromosomal instability pathway and microsatellite instability pathway, are known as the main pathways of the development of colorectal cancer. These are almost always mutually exclusive and tumors developed through each pathways show distinct clinicopathologic features. For the reason, molecular markers which represent each genomic instability pathways have been a candidate for translational research to find out prognostic or predictive factors. Loss of heterozygosity and aneuploidy are the hallmark of chromosomal instability and regarded as poor prognostic markers, whereas tumors with high frequency of microsatellite instability show better prognosis than microsatellite stable tumor. As a predictive factor of response from chemotherapy, loss of heterozygosity seems to be associated with a survival benefit from 5-FU adjuvant therapy. MSI-H has been reported as a predictive factor for poor response to 5-FU adjuvant chemotherapy. However, these molecular markers are not accepted to use in the clinic yet, since some of this kind of studies reported contradictory results. Further study will be needed to make more concrete evidences for these markers and to identify new molecular markers for routine use in the clinic.
Aneuploidy ; Chemotherapy, Adjuvant ; Chromosomal Instability ; Colorectal Neoplasms ; Fluorouracil ; Genomic Instability ; Loss of Heterozygosity ; Microsatellite Instability ; Microsatellite Repeats ; Prognosis ; Translational Medical Research

Gastrointestinal hemangioma is a relatively uncommon benign vascular tumor that can occur anywhere in the gastrointestinal tract. It is the second most common vascular lesion of the colon and a clinically important entity because of the possibility of massive hemorrhage when complicated. In gross appearance, hemangioma presents variously as a pedunculated, subpedunculated, or flat elevated lesion similar to a submucosal tumor. A typical case of hemangioma is relatively easy to diagnose because the lesion presents as translucent blue-purple vessels under the mucosa. However, it can be difficult to diagnose in some cases, especially if it does not have its usual characteristic color or is covered with normal mucosa. We incidentally found a colonic hemangioma that had the unusual appearance of a pedunculated polypoid lesion with normal mucosa. It was misdiagnosed as a pedunculated polyp with a long, thick neck and treated by using an endoscopic mucosal resection.
Caves ; Colon ; Gastrointestinal Tract ; Hemangioma ; Hemangioma, Cavernous ; Hemorrhage ; Mucous Membrane ; Neck ; Polyps

Although rectal procidentia is not an uncommon disease, presentation of more proximal segments of the large bowel through the anus is extremely rare. A case with sigmoido-recto-anal prolapse secondary to a large adenoma of the sigmoid colon is reported herein. A 28-yr-old man with an anal prolapsing mass was admitted to our hospital. Preoperative CT scan showed a sigmoid-recto-anal prolapse. An emergency operation was decided upon because the prolapsed segment was irreducible and because its viability was questionable. After a manual reduction of the mass, an anterior resection was performed under general anesthesia. The pathologic diagnosis of the resected specimen was a large villo-tubular adenoma.
Adenoma ; Adenomatous Polyps ; Adult ; Anal Canal ; Anesthesia, General ; Colon, Sigmoid ; Emergencies ; Humans ; Intussusception ; Prolapse

The most common presentation of abdominal tuberculosis is an ileocecal disease, but isolated appendicular involvement is rarely seen. It is difficult to make diagnosis of intestinal tuberculosis because it may mimic many other intestinal diseases. The symptoms are nonspecific such as fever, fatigue and weight loss. A 35-yr-old woman with no remarkable past medical history was admitted due to intermittent abdominal pain of 3 mo duration. The patient underwent laparoscopy-assisted partial ileocecectomy including diseased appendix. Tuberculous appendicitis was finally diagnosed with all considerations of possible pathological results. We report a case of acute appendicitis due to tuberculous involvement with a review of the literature.
Abdominal Pain ; Appendicitis ; Appendix ; Fatigue ; Female ; Fever ; Humans ; Hydrazines ; Intestinal Diseases ; Tuberculosis ; Weight Loss

Stoma operations are one of the most frequently performed operation by the colorectal surgeons. And the consequences of the stoma operation of the patients are well known. However, most colorectal surgeons who performed stoma operation were not aware of the problems that are part of the rehabilitation of the ostomates. In order to elucidate the current status of the stoma studies in Korea, literature reviews were performed by using the Korean medical literature database. Most of the Korean literatures written by the colorectal surgeons are related with the postoperative complications of stoma surgeries. Very few papers are concerned with rehabilitation issues including postoperative adaptation of ostomates, quality of life, and stoma nursing care. Recently, more and more papers concerning the stoma rehabilitation issues were published and the interests in the patient's adjustment to a change in body function are growing. Stoma rehabilitation program should be the part of the nations' welfare program which would be successful with the active participation of the colorectal surgeons, enterostomal therapists and ostomates. We, colorectal surgeons, and the Korean Society of Coloproctology should do the major role in stoma-related researches and cooperate with the enterostomal therapists and ostomates organizations in order to establish and develop the stoma rehabilitation program in Korea.
Humans ; Korea* ; Nursing Care ; Postoperative Complications ; Quality of Life ; Rehabilitation

Malignant intestinal lymphoma complicating ulcerative colitis has been reported. Although the association of colorectal cancer with ulcerative colitis is well described, the association of intestinal lymphoma, ulcerative colitis and prior immunosuppression remains unclear. However, it is important to be aware of the possible risk of lymphoma and carcinoma when patients shows unexpected signs of deterioration or when the clinical course of ulcerative colitis is atypical. Substantial biopsies with colonoscopy are required to make an unequivocal diagnosis in such patients. We report the case of non-Hodgkin's lymphoma in ulcerative colitis with review of the literature.
Biopsy ; Colitis, Ulcerative* ; Colonoscopy ; Colorectal Neoplasms ; Diagnosis ; Humans ; Immunosuppression ; Lymphoma ; Lymphoma, Non-Hodgkin* ; Ulcer*