20-40% of cases of acute transverse myelitis are attributed to viral infections, although the specific viral etiology is only rarely identified. We have studied one patient with transverse myelitis in association with acute hepatitis B virus infection. Hepatitis virus should be considered as rare cause of transverse myelitis.
Hepatitis B virus* ; Hepatitis B* ; Hepatitis Viruses ; Hepatitis* ; Humans ; Myelitis, Transverse*

The authors presented a family whose 4 siblings had been suffered from oculopharyngeal muscular dystrophy of autoscmal recessive trend, with symptoms of progressive ptosis, external ophthalmoplegia, dysarthria, dysphagia and facial muscle atrophy, and we performed HLA study on these 9 family members which showed no interrelationship between oculopharyngeal muscular dystrophy and HLA Haplotypes.
Atrophy ; Deglutition Disorders ; Dysarthria ; Facial Muscles ; Haplotypes ; Histocompatibility Testing* ; Humans ; Muscular Dystrophy, Oculopharyngeal* ; Ophthalmoplegia ; Siblings

A 19-year-old man with periodic alternating nystagmus (PAN) is presented. He reported that he had had oscillopsia and head oscillations for as long as he could remember. Acquired diseases associated with PAN were ruled out with various laboratory aids. This case is believed to be the first reported case of PAN in Korea.
Head ; Humans ; Korea ; Nystagmus, Pathologic* ; Young Adult

In the 2 patients with hemichorea brain CT scan reveals hypodensity on the contralateral caudate nucleus and the region near contralateral caudate nucleus. The pathoanatomy of similar cases in literature are reviewed with the reference to the location of responsible lesions.
Brain ; Caudate Nucleus ; Chorea* ; Humans ; Tomography, X-Ray Computed

Septo-optic dysplasia is an uncommon developmental disorder consisting of septum pellucidum angenesis, optic nerve hypoplasia, congenital nystagmus, seizure and multiple endocrine dysfunction. Clinically mild forms of septo-optic dysplasia and syndrome of absent septum pellucidum are now easily detected by computed tomography. We report two cases of septo-optic dysplasia with consistent radiographic findings with the anomaly.
Nystagmus, Congenital ; Optic Nerve ; Seizures ; Septo-Optic Dysplasia* ; Septum Pellucidum

A case of diabetic proximal motor neuropathy presented with left brachial paralysis is reported. In a 52-year-old male patient, the initial manifestation was the weakness of the predominantly proximal part of left upper limb, which progressed to the lower limb of the same side. There complications gave the opportunity to recognize and treat diabetes mellitus more promptly. The weakness recovered after one month with diabetic control but recurred mainly in the same lower limb and eventually achieved good functional result three months after.
Diabetes Mellitus ; Humans ; Lower Extremity ; Male ; Middle Aged ; Paralysis* ; Upper Extremity

Paroxymal nocturnal hemoglobinuria is a kind of intravascular hemolytic anemia due to acquired corpscular defects, and is not rare in this country. The corpscular defect is originated from hematopoietic stem cells, and white blood cells and platelets are also involved. Consequently, the major complications which might affect mortality and morbidity include thrombotic phenomena, especially hepatic and cerebral venous thrombosis. This is a case report of cerebral venous thrombosis with hemiparesis, seizure and change of consciousness in paroxysmal nocturnal hemoglobinuria accompanied by intravascular hemolysis. The diagnosis is confirmed by CT brain scan and cerebral angiography and the patient is effectively treated with antiplatelets, anticonvulsants and steroids.
Anemia, Hemolytic ; Anticonvulsants ; Brain ; Cerebral Angiography ; Consciousness ; Diagnosis ; Hematopoietic Stem Cells ; Hemoglobinuria ; Hemoglobinuria, Paroxysmal* ; Hemolysis ; Humans ; Leukocytes ; Mortality ; Paresis ; Seizures ; Steroids ; Venous Thrombosis*

Diseases of the peripheral nervous system are one of the most difficult subjects in neurology partly in that specific etiologies are often not found. Among peripheral neuropathies of unknown causes, an association of monoclonal gammopathies has been observed. Monoclonal gammopathies are disorders characterized by proliferation of a single clone of plasma cell that produces monoclonal proteins. Here we report two cases of chronic sensorimotor polyneuropathy with monoclonal gummopathy of undetermined significance, who showed no evidences of multiple myeloma, macroglobulinemia, systemic amyloidosis, or other neoplasms. One case is also associated with hyperthyroidism and cryoglobulinemia.
Amyloidosis ; Clone Cells ; Cryoglobulinemia ; Hyperthyroidism ; Monoclonal Gammopathy of Undetermined Significance* ; Multiple Myeloma ; Neurology ; Paraproteinemias* ; Peripheral Nervous System ; Peripheral Nervous System Diseases ; Plasma Cells ; Polyneuropathies* ; Waldenstrom Macroglobulinemia

Hypertrophy of the calves has been described in spinal muscular atrophy (SMA) syndrome. Pearn and Hudgson described a new spinal muscular atrophy syndrome characterized adolescent onset, gross hypertrophy of the calves, and a slowly progressive clinical course. We saw a 16-year-old female who had weakness of the thighs with atrophy and hypertrophy of calfmuscles. The patient was studied with EMG and muscle biopsy and thought to be as SMA with hypertrophied calf-muscles.
Adolescent ; Atrophy ; Biopsy ; Female ; Humans ; Hypertrophy* ; Muscular Atrophy, Spinal* ; Thigh

Chymopapain was discovered by Jensen in 1941, and in 1963 Smith demonstrated the chondrolytic properties of chymopapain. Since then, many patients have been injected with this agent. Although there are evidences of neurotoxicity to chymopapain in animals, adverse effects in humans have rarely been reported. We present a case delayed onset of paraplegia after chymopapain chemonucleolysis and review the neurotoxicities to chymopapain.
Animals ; Chymopapain ; Humans ; Intervertebral Disc Chemolysis* ; Paraplegia*