No abstract available.
Marchiafava-Bignami Disease* ; Thalamus

No abstract available.
Hyperaldosteronism* ; Paralysis*

Polymyositis(PM) is one of idiopathic inflammatory myopathy, characterized by proximal muscle weakness, myalgia and muscle enzyme elevation. Currently the main pathogenesis is well documented, the cell-mediated immunity. We experienced a case of polymyositis associated with hepatitis, developed after hepatitis B virus(HBV) infection. This virus-induced autoimmunity seems to result from the cross-reactivity between muscle protein and B-viral antigen, so called antigenic mimicry. This relation of PM and HBV is more significant in Korea because of the epidemicity of HBV infection.
Autoimmunity ; Hepatitis B virus ; Hepatitis B* ; Hepatitis* ; Immunity, Cellular ; Korea ; Molecular Mimicry ; Muscle Proteins ; Muscle Weakness ; Myalgia ; Myositis ; Polymyositis*

Both the inherited and acquired forms of vitamin E deficiency are implicated in chronic progressive neurological deficit. The clinical features include ataxia and prominent proprioceptive loss with depressed or absent tendon reflexes. We report a 63-year-old man with vitamin E deficiency syndrome caused by chronic fat malabsorption following exten-sive intestinal resection. Although replacement therapy prevented further deterioration, symptomatic improvement was not observed for two years. Early diagnosis and appropriate treatment is crucial.
Ataxia ; Early Diagnosis ; Humans ; Middle Aged ; Reflex, Stretch ; Vitamin E Deficiency* ; Vitamin E* ; Vitamins*

Methyl bromide is a commonly used fumigant to disinfect soil, grains, and warehouses. The accumulation of danger-ous concentrations can produce various neurotoxic effects in humans. A 45-year-old man, who had worked in the fumi-gation business, presented with polyneuropathy, optic neuropathy, and cerebellar sign, and serially sampled blood, urine and cerebrospinal fluid showed significant elevation of methyl bromide concentration. Regular education to workers and strict adherence to the safety precautions are needed to avoid the risk of toxicity associated with methyl bromide fumigation.
Edible Grain ; Cerebellar Ataxia* ; Cerebrospinal Fluid ; Commerce ; Education ; Fumigation ; Humans ; Middle Aged ; Optic Nerve Diseases* ; Poisoning* ; Polyneuropathies* ; Soil

We report a rare case of meningioangiomatosis in a 22 year-old man who has refractory partial seizures. Seven of 11 seizures had ictal onset zone at the perilesional medial and orbitofrontal areas of frontal lobe and 4 seizures arose from the mesial temporal area. After having lesion resection and an anterior temporal lobectomy with amygdalohippocam-pectomy, the patient no longer suffered from seizures. The epileptogenic foci were found not only in the intra-/peri-lesional area but also in remote area.
Anterior Temporal Lobectomy ; Epilepsy* ; Frontal Lobe ; Humans ; Seizures ; Young Adult

Trauma has infrequently been mentioned as a cause of movement disorders. The trauma to the central nervous system can cause tremors and dystonia is well established. Recently, some clinicians raised the possibility that injury to the peripheral nervous system can also produce these and other movement disorders. We describe two patients in whom involuntary movement developed transiently after trauma of the peripheral nervous system. We reviewed the reported examples in which trauma was associated with dyskinesias and discussed the possible etiologic role of trauma.
Central Nervous System ; Dyskinesias* ; Dystonia ; Humans ; Movement Disorders ; Peripheral Nerves ; Peripheral Nervous System ; Tremor

Ophthalmoplegia may accompany herpes zoster ophthalmicus(HZO). A 60-year-old woman with rheumatoid arthritis suffered from HZO in the right side consecutively developed a mydriasis and abduction deficit in the right eye. CSF examination revealed pleocytosis and increased protein, while magnetic resonance imaging of the brain was normal. She was treated with intravenous acyclovir for 7 days. Ophthalmoplegia was completely resolved over the following 8 weeks, but mydriasis persisted.
Acyclovir ; Arthritis, Rheumatoid ; Brain ; Female ; Herpes Zoster Ophthalmicus* ; Herpes Zoster* ; Humans ; Leukocytosis ; Magnetic Resonance Imaging ; Middle Aged ; Mydriasis ; Ophthalmoplegia*

Mal de debarquement syndrome refers to the prolonged sensation of rocking and swaying that is experienced on the return to land following a sea voyage or an air travel. We report a man who developed mal de debarquement syndrome after a 4-day-boat-trip. Apogeotropic nystagmus during head turning in supine position was the only finding. Mal de debarquement syndrome should be considered in the differential diagnosis of direction-changing positional nystagmus, especially when patients do not complain of vertigo with nystagmus.
Diagnosis, Differential ; Head ; Humans ; Nystagmus, Physiologic* ; Sensation ; Supine Position ; Vertigo

Epilepsy with an onset of initial episode in adult life is not a rare event. It is generaly considered that the onset of seizure after early adulthood may turn out to be an ominous sign and should be investigated thoroughlyly to rule out an organic brain lesion. The present study of 206 patients with epilepsy of late onset (over 20 years of age), who admitted to or were consulted Department of Neurology, Seoul National University Hospital from January 1982 to December 1985, was undertaken to seek treatable causes and re-evaluate the relationship between clinical evaluation, electroencephalography and computerized tomography of the brain. Patients'ages ranged from 20 to 74.132 were men and 74, women (64% and 36%, respectively). Major causes were infectious or inflammatory origin (45.2%) and cerebrovascular disorders (21.8%). Causes remained unknown in 14.2%. Comparison of the CT findings with EEG showed a close relationship between the local EEG slowing and the focal CT abnormality. Therapeutic responses to antiepileptic drugs were not favorable in patients with encephalitis or meningoencephalitis.
Adult ; Anticonvulsants ; Brain ; Cerebrovascular Disorders ; Electroencephalography ; Encephalitis ; Epilepsy* ; Female ; Humans ; Male ; Meningoencephalitis ; Neurology ; Seizures ; Seoul