1.Use of high dose pralidoxime contribute to reduce mortality rate of organophosphate poisoning
Journal of Vietnamese Medicine 2005;311(6):51-57
The research of 108 patients taken organophosphate to kill oneself who were treated by the new regimen in which, pralidoxime (PAM) were indicated according to poisoning level and adjusted by two factors: the change of plasma ChE and the adjustment of essential atropine dose. The results were compared with control groups including 54 patients treated by old regimen. Age, sex and ChE activity characteristics in 2 groups when hospitalized were the same. Compared with control group, the patients of study group received higher doses of PAM. The doses are very different between the patients depending on poisoning level. Therefore, predictive indicators in patient group were better than controlled group, especially the mortality rate (1.85% vs. 13%). The regimen achieved good results
Phosphoric Acid Esters
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Mortality
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Phosphoric Acid Esters
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Poisoning
2.Assessment on farmers’ knowledge, attitude and practice of safety vegetable production in Vu Phuc commune, Thai Binh city
Journal of Vietnamese Medicine 2005;309(4):1-5
Research on farmers’ knowledge, attitude and practice of safety vegetable production process showed that: the incident of farmers had knowledge of safety vegetable production was 50.98%, in which 37.19% was aware of IPM, 57.10% was aware of safety vegetable criterion. 83.74% of the farmer used dried and powdered night soil, 100% used nitrogen fertilizer and 2.95% applied fertilizer-water for vegetables. The incident of farmers using covered fertilizer was rather high (97.06%). However, the time for covering the fertilizer from 3 to 6 months was 95.17% in Van Xuan, and 63.14% in Vu Phuc. 85.0% of the farmers used dried and powdered night soil for leaf-eating vegetables, 61.17% used this kind of fertilizer for tuber-eating vegetables. The amount of nitrogen fertilizer was at normal level < 100 kg/ha/crop. Many poisonous chemicals were forbidden such as Moniter, Wofatox are still being used by Vu Phuc farmers. The time isolating the chemical was 10 days in Van Xuan (100%), in Vu Phuc (58.86%)
Vegetables
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Safety
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Knowledge
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Attitude
3.Initial studied about role of anti ANA and dsDNA on the patients of scleroderma
Journal of Vietnamese Medicine 2005;309(4):6-9
42 patients were diagnosed as scleroderma and treated at Bach Mai Hospital in three years (1991-1993). 90.47% was female, the age ranged from 18 to 63 years. The control group consisted of 20 healthy normal persons. Results: the rate of anti dsDNA positive with serum 1/10 was 30.95%; the rate of anti ANA positive with serum 1/40 was 71.42% in the patients with scleroderma. In the control group, there is no person who had anti dsDNA positive with serum 1/10. The rate of anti ANA positive with serum 1/40 is 10%. Positive anti dsDNA rate is not high (30.95%). There is no case of scleroderma which had negative anti ANA but positive anti dsDNA in the patients group. The appearance of anti dsDNA and anti ANA with digestive and cardiovascular disorder had a high rate. Anti ANA is more valuable in following the nephroinjuries in the scleroderma than dsDNA
Scleroderma, Systemic
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Diagnosis
;
Therapeutics
4.Evaluation of the effect of nicardipin (loxen) in treatment of severe hypertension
Journal of Vietnamese Medicine 2005;309(4):10-18
Prospective study was carried out on 31 patients with severe hypertension treated in Vietnam Heart Institute. Those subjects were treated with intravenously LOXEN in the first 10 hours, measured blood pressure by the Holter. Results: nicardipin (LOXEN) is calci channel blocker with a good antihypertensive effect in treatment of severe hypertension. At initial dose 7.5 - 8.0 mg/hour, after the sixth minute, the drug had effect of antihypertention (p<0.05), at the 18th minute, blood pressure reduced by15%. At the normal dose 2-3 mg/hour by the time of 1, 4 and 10 hour, blood pressure gradually decreased and reached 16%, 22% and 24%, respectively compared to initial blood pressure. Nicardipin is easy to use and well tolerate, there was no patients with allergy or died of the medicament
Hypertension
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Therapeutics
5.Catastrophes and complication during surgically remove of renal calculi intrasinus by Resnick.M.I
Journal of Vietnamese Medicine 2005;309(4):19-22
73 cases of renal calculi intrasinus were surgically operated by Resnick.M.I (1981) in Urology Department of Hospital N¬¬0 103. Mean renal thick of parenchyma 1.020.28 cm, urinary infection preoperatively 51.16%. 18 cases have catastrophes (24.66%), intraoperative and postoperative complications included 9 cases have catastrophes intraoperatively (12.33%): bleeding (1 case), tearing of the renal venous (2 cases), neck of the calix tear (1 case), tearing of peritoneum (1 case). And 9 cases had postoperative complications (12.33%): hemorrhage secondary (3 cases), urinary fistula (2 cases), urinary infection (4 cases)
Kidney Calculi
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Surgery
6.Investigating one case of deletion of 27 exons espanding at rod domain of dystrophin gene in a Duchenne Muscular Dystrophy
Journal of Vietnamese Medicine 2005;309(4):23-28
A majority deletion of 27 exons expanding from 8-34 at rod domain of dystrophic gene was identified in a Duchene Muscular Dystrophy (DMD) patients. Polymerase chain reaction (PCR) was used to analyze the deletion. The deletion caused an out of frame mutation leading to nonsense mutation which early stops code in exon 35 of dystrophic gene. The DMD gene was analyzed at both genomic DNA and mRNA levels. Identification of deletion at mRNA level is very useful for rapid diagnosis of DMD patients and avoid missing some mutations that we can’t identify at DNA level
Muscular Dystrophy, Duchenne
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Dystrophin
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Genes
7.Investigation of eye complications in diabetics in Ha Noi communities
Journal of Vietnamese Medicine 2005;309(4):29-33
Investigation of 72 patients with diabetics who were ≥ 16 years old, in 20 communes of Gia Lam, Soc Son and Dong Da districts, Ha Noi, from June to September 2001. Results: the common eye complications included retinopathy, cataract, uveites, and conjunctivitis. In diabetic’s subjects, three common ophthalmic diseases such as amblyopia, retinopathy and cataract in males were more distinct than in females. But ophthalmitis (uveites, conjunctivitis) in females were more than in males. The old age and the long duration of diabetics were the risk factor related to increase of retinopathies and amblyopia
Diabetes Mellitus
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Diabetes Complications
8.Reporting one case of abnormally high urine hCG level in the pregnancy
Journal of Vietnamese Medicine 2005;309(4):34-36
Reporting one case of abnormal high urine hCG level in the pregnancy. The abnormal high level was still in allowed limits, even higher than normal level. The maximum hCG level was observed at 11 weeks and 5 days of gestational age following the first days of the last menstrual periods. The symptoms such as nausea, vomiting would be severe with very low hCG, last until hCG achieved maximum. This patient was successfully managed with aminazin
Chorionic Gonadotropin
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Pregnancy
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Urine
9.Characteristics of cellular – immunity in scleroderma
Journal of Vietnamese Medicine 2005;309(4):37-39
Scleroderma is the autoimmune diseases. It has clinical characteristics of other autoimmune diseases such as: systemic lupus erythmatosus, juvenile rheumatoid arthritis…Appearance of antinuclear factors, rheumatofactors and increased blood gamma globulin showed that the immunity in this disease is abnormal. Study on 20 patients with scleroderma who were treated at the Allergy Department in two years (1984-1985) showed that: the ratio of leukocyte in the patients was not lower than that in control groups; the percentage of T lymph in peripheral blood was lower; B lymph in peripheral blood increased lightly; T gamma in peripheral blood was lower; the percentage of lymphocyte transformation with Con A and lymphocyte transformation with PHA were lower; lymphocyte transformation with PWM increased
Scleroderma, Systemic
;
Diagnosis
10.Evaluation of left ventricular function in 64 patients with hypertension by Doppler ultrasound
Journal of Vietnamese Medicine 2005;309(4):40-46
Study was performed in 64 patients with hypertension who were treated at Viet Tiep Hospital, Hai Phong city from 2001 to 2002. The control group consisted of 36 normal healthy persons. Results: in patients with hypertension, the LA, Dd, IVSd, LWPd, LVMl increased more highly than in the control group. However, the evaluated parameters of the left ventricular function such as EF%, FS%, T%, lVS, T% LWP, the distance of E-lVS and curve EF of the heart valve decreased more than the normal persons. Only 15.62% of patients with hypertension had the left ventricular function decreased (EF<55%). While 90.62% of those patients had left ventricular function disorders. Reduced elastic ability of left ventricular occurred in majority of patients with hypertension (93.75%). The type of “unnormal” disorder of diastolic function occurred in 2 patients (3.12%)
Hypertension
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Ventricular Function, Left
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Ultrasonics