1.Do medical lecturers need to be specially trained in teaching?
Journal of University of Malaya Medical Centre 2008;11(1):12-17
Over the years, the emphasis on research practices in healthcare has received more recognition than the
emphasis on teaching practices. Also, in contrast to the strong focus on aligning care-giving practices
with evidence of effectiveness; aligning educational practices with evidences of effectiveness has
continued to be neglected. This creates a chasm that hinders the delivery of effective health practices.
Many challenges in the current healthcare delivery system warrant a call for a revamp of health
professionals’ education, and for a greater focus in effective teaching, assessment and supervision.
This paper highlights the current challenges in health professional education (as revealed by the Institute
of Medicine, IOM, 2003). It focusses on fi ve key issues for promoting teaching excellence, and supports
the move for new lecturers to be educationally trained so that ‘teaching for learning’ becomes current,
effective and enjoyable. More importantly, the vision for health professional education that “all health
professionals are educated to deliver patient-centred-care as members of an interdisciplinary team,
emphasising evidence-based practice, quality improvement approaches, and informatics” can be
attained. This vision has important implication for medical lecturers as it means they have to be better
educated to teach in order to be prepared to meet the demands of a reformed healthcare system.
Education, Medical
2.Chronic myeloid leukaemia presenting as priapism- how should we treat these?
Htun TH ; Dublin N ; Parameswaran M ; Razack AH ; Chua CB
Journal of University of Malaya Medical Centre 2008;11(1):27-29
Priapism is a urological emergency. The treatment for ischaemic priapism is usually
cavernosal aspiration with or without cavernosal irrigation. Some patients may need surgical intervention
-the various shunt procedures. We report a 21-year-old man with priapism secondary to chronic
myeloid leukemia who needed a combined medical and surgical management. He underwent a spongiocavernosal
shunt as well as cytoreductive chemotherapy to achieve complete detumescence. Therefore,
cytoreductive chemotherapy is an adjunct in diffi cult to treat priapism associated with chronic myeloid
leukemia
Leukemia, Myeloid
3.Sudden visual loss in acute leukaemia
Tengku Kamalden TA ; Nurliza K ; Haris AR
Journal of University of Malaya Medical Centre 2008;11(1):30-32
The presenting signs of acute leukaemia occur as a result of bone marrow failure and organ infi ltration. Increased bleeding tendencies are seen on the skin, gums and mucosal lining.
Bleeding in the posterior segment of the eye, namely the retina and vitreous, may occur, but do not
usually cause any visual disturbances. This case demonstrates visual loss as a result of premacular
subhyaloid haemorrhage in acute leukaemia.
Leukemia, Myeloid, Acute
4.Anterolateral thigh free flap in reconstruction of oral cavity malignancy: UMMC experience
Journal of University of Malaya Medical Centre 2008;11(1):33-36
Oral cavity malignancy reconstructive surgery has advanced from pedicle fl aps to
microvascular free tissue transfer. Previously, reconstruction of these defects were done using radial
forearm free fl ap in this centre. We report our experience using anterolateral thigh free fl ap in a 49
year old lady with squamous cell carcinoma of the tongue. Excision of tumour left a defect which was
later reconstructed using microvascular free tissue transfer using the right anterolateral thigh free fl ap.
The fl ap was well taken up at the recepient site and no evidence of fl ap failure noted post operatively
and on completion of radiotherapy. She was able to maintain comprehensible speech and swallowing
ability.
5.Prevalence of sleep disturbance among nurses in a Malaysian government hospital and its association with work characteristics
Nazatul SM ; Saimy I ; Moy FM ; Nabila AS
Journal of University of Malaya Medical Centre 2008;11(2):66-71
The objective of this study was to determine the prevalence of sleep disturbance with work
characteristics among nurses in the Melaka Hospital, Malacca, Malaysia. This was a cross sectional
study conducted in Melaka Hospital. Universal sampling was conducted and a Malay version
of the Pittsburgh Sleep Quality Index (PSQI) questionnaire was used in data collection. Sociodemographic
characteristics such as age, marital status, number of children and work characteristics
such as type of work schedule and duration were also enquired. Factors associated with poor sleep
quality were compared between those nurses with good sleep quality by using logistic regression.
There were 607 nurses who completed the questionnaire with a response rate of 73.1%. There
was a moderate prevalence (57.8%) of poor sleep quality (PSQI > 5) in all study subjects. The
prevalence of sleep disturbance was more widespread among nurses who worked shifts (62.0%)
compared to non-shift working nurses (41.5%) p<0.001. A logistic regression analysis showed that
age, marital status and unit group were the major associating factors of poor sleep quality. Sleep
disturbance decreased with increasing age (OR = 0.42, 95% CI 0.25, 0.73) while married nurses
(OR = 2.3, 95% CI 1.42, 3.82) and those in the category of intensive group (OR = 2.1, 95% CI 1.1, 4.1)
were more prone to have sleep disturbances. In conclusion, this study revealed moderate
prevalence of sleep disturbance among nurses working in Melaka Hospital but it was not associated
with the work shifts. Age, marital status and work environment especially in the intensive
group unit seemed to be factors associated with reduced global sleep quality among nurses in
this study.
6.Intrahepatic subcapsular hematoma complicating laparoscopic cholecystectomy
Journal of University of Malaya Medical Centre 2008;11(2):83-85
A 65-year-old lady with cholelithiasis underwent an elective laparoscopic cholecystectomy
(LC) and was discharged on post-operative day 2. She was re-admitted after five days with
right hypochondriac pain and fever. Investigations revealed a drop in hemoglobin. Computed
tomography showed a large intrahepatic subcapsular collection without intra-abdominal
collection. She was treated with intravenous antibiotics. Percutaneous aspiration of intrahepatic
subcapsular collection under ultrasound guidance revealed old blood. Hence diagnosis of
intrahepatic subcapsular hematoma (ISH) was made. She improved and was discharged after a two
weeks’ hospital stay. Follow-up ultrasonography examination two months later revealed complete
resolution of the hematoma. We report this case due to its rarity and review the previously
documented cases of this complication.
7.Intrapulmonary bronchogenic cyst: single case report
How SH ; Tee HP ; AR Amran ; ARM Fauzi
Journal of University of Malaya Medical Centre 2008;11(2):86-88
Intrapulmonary bronchogenic cyst is a rare congenital lesion originating from abnormal budding
of the embryonic foregut. It is less common than mediastinal bronchogenic cyst. We describe
a case of intrapulmonary bronchogenic cyst and discuss the treatment of this condition.
8.Congenital bilateral aplasia of vas deferens (CBAVD): a reminder to clinicians
Koh PS ; Shanggar K ; Razack AH ; Lee G.
Journal of University of Malaya Medical Centre 2008;11(2):89-90
Male factor infertility which accounts for 30-50% of infertility is a major problem faced by married
couples. Congenital absence of the vas deferens, though uncommon, remains the most common
abnormality seen in extratesticular ductal and ejaculatory system, accounting for 1-2% of male
infertility. It may be unilateral or bilateral. Association with renal abnormality has also been
reported with congenital absence of vas deferens (1). The patients are asymptomatic and the
congenital abnormality is usually detected when investigation for infertility is carried out. We
present a case of an unusual presentation of congenital bilateral absence of vas deferens (CBAVD).
9.Systematic review and meta-analysis: a glossary
Journal of University of Malaya Medical Centre 2007;10(1):3-10
Systematic review is a comprehensive review of research findings in which all of the
primary studies are systematically identified, appraised and summarised using an explicit and
reproducible methodology. Meta-analysis is the statistical component of a systematic review in which
combinable studies are drawn together via a statistical process. Systematic reviews and meta-analyses
are routinely being used in the evidence-based approach to medicine. These short notes intend to
highlight important terms in systematic-review and meta-analysis. It is a beginner’s guide for health
care professional of any discipline involved in research or practice who seeks to gain more
comprehensive understanding of important terms used in systematic review and meta-analysis.
10.Quantitative evaluation of chimerism status following haematopoetic stem cell transplantation using a microchip electrophoresis system
Daud SS ; Ibrahim K ; Ariffin H
Journal of University of Malaya Medical Centre 2007;10(1):11-16
We aimed to establish a method for quantitative analysis of mixed haematopoietic
chimerism based on microchip electrophoresis of selected molecular markers following PCR
amplification for accurate monitoring of graft status post-transplantation. A 12-year-old girl with
relapsed acute lymphoblastic leukaemia who underwent allogeneic bone marrow transplantation had
qualitative chimerism analysis using short tandem repeat markers at three time points following the
procedure. Her archived DNA samples were then used to test the ability to correlate her clinical course
with changes in the quantity of donor chimerism at the different time points. Quantitative chimerism
analysis was performed on the Agilent 2100 bioanalyser and donor-recipient ratios were calculated
from generated electropherograms. Complete donor chimerism (98%) was demonstrated three weeks
post- transplantation. Decreasing amount of donor chimerism to 24% was shown after three months
and this concurred with clinical relapse. Following a second transplant, full donor chimerism was reestablished
where donor chimerism rose to 100%. High resolution microchip electrophoresis could be
useful in predicting the occurrence of increasing recipient chimerism which may herald impending
relapse in patients while the disease burden is still low. This investigational approach may provide
useful information for clinicians to select appropriate intervention strategies to ensure successful
transplantation.