1.Clinical observation on Ren Zhu Jian Wei Granules for treatment of 88 cases of precancerous lesion of stomach
Chanting LI ; Aiyun WANG ; Zhaawei SHAN
Journal of Traditional Chinese Medicine 1992;0(12):-
To observe clinical therapeutic effect of Ren Zhu Jian Wei Granules on precancerous lesion of stomach. Methods: 130 cases of precancerous lesion of stomach were randomly divided into tow groups, the treatment group (88 cases) treated with Ren Zhu Jian Wei capsules and the control group (42 cases) treated with Wei Fu Chun Tablets, and clinical data were analyzed. Results: The comprehensive therapeutic effect was 92. 0% in the treatment group and 73. 8% in the control group; and the clinical therapeutic effect was 94. 3% in the treatment group and 78. 6% in the control group with a significant difference (P
2.Effect of Fu Zheng Hua Yu Recipe on hepatic sinusoid capillarization in the rat of dimethyl nitrosamine-induced hepatic fibrosis
Xiong LU ; Ping LIU ; Chenghai LIU
Journal of Traditional Chinese Medicine 1993;0(02):-
Objective: To investigate the effect of Fu Zheng Hua Yu-319 Recipe on hepatic sinusoid capillarization in the rat of hepatic fibrogenesis. Methods: Hepatic fibrosis model rats were induced by intraperitoneal injection of dimethyl nitrosamine (DMN). thrice a week for 4 weeks, and they were divided into the treatment group which were treated with Fu Zheng Hua Yu-319 Recipe for 4 weeks, and the model control group. Serum and hepatic tissue were taken for examination of pathohistology, microstructure by electron microscopy, immunohistochemistry, and hydroxyproline content in the liver tissue and hepatic function. Results: In the normal group, peripheral cytoplasma of endothelial cells in the hepatic sinusoid is very thin with a lot of small fenestra, and no basement membrane under endothelium was found. In the model group, crookedness and stricture of the hepatic sinusoid were found , and the fenestra in cytoplasma of the endothelial cell reduced or disappeared with obvious basement membrane, and hemorrhage necrosis in the liver tissue could be found, with a great proliferation of connective tissue in the portal area, and fibrous septum extended towards into the lobuli, the content of hydroxyproline (HYP) in the liver tissue increased significantly. The VI factor-related antigen, a-actin of smooth muscle, LM and type IV collagen positive staining on the hepatic sinusoid wall increased significantly with a wider range as compared with the normal rat. In the treatment group, the extents of crookedness and stricture of hepatic sinusoid and reduction and disappearence of endothelial fenestra were lower, with thiner or discontinuous basement membrane, and a part of hepatic sinusoid construction approached to normal, and degeneration and necrosis of hepatic cells were mild and fibrous septum in the liver tissue decreased significantly, and HYP content decreased significantly (P
3.Clinical observation on 102 cases of chronic pelvic inflammation treated with Qi Jie Granules
Qin ZHANG ; Jialin HE ; Shaoshan HE
Journal of Traditional Chinese Medicine 1993;0(02):-
Objective: To investigate the therapeutic effect of Qi Jie Granules on chronic pelvic inflammation. Methods: 102 cases of chronic pelvic inflammation were treated by Qi Jie Granules, and 70 cases were treated with Fu Ke Qian Jin Tablets as control. Their therapeutic effects, subgroups of T-lymphocytes and hemorhelogical indexes were investigated. Results: The total clinical effective rate was 96. 08% in the treatment group and 84. 29% in the control group, with a significant difference between the two groups (P
4.Clinical study on Jian Shen Li Shui No. 1 for treatment of 60 cases of cerebral edema at acute stage due to acute cerebral hemorrhage
Tai LIU ; Zhaoru CAN ; Hui LU
Journal of Traditional Chinese Medicine 1993;0(02):-
Objective: To investigate the therapeutic effect and safety of Jian Shen Li Shui No. 1 for treatment of acute cerebral hemorrhage. Methods: The patients enrolled were randomly devided into 3 groups. The group A were treated with Jian Shen Li Shui No. 1, the group B with Xing Nao Xiao Zhong Capsules and the group C with 20% mannitol. Symptoms and signs, changes of urine volume, quality of life, routine examination of blood, urine and feces, function of liver and kidney, electrocardiogram, blood lipid, sugar, electrolytes, reological changes were observed. Results: The total effective rate in the group A was superior to that in the group B(P0. 05) ; while the cured and markedly effective rate in the group A was better than that in the group C (P
5.Characteristics of arrhythmia symdrome in the south erea and clinical study on TCM prevention and treatment
Yuhua JIA ; Xuegang SUN ; Xiaoshan ZHAO
Journal of Traditional Chinese Medicine 1993;0(03):-
Objective: The caracteristics of rapid arrhythmia in the south region of our country are simultaneous appearance of phlegm. heat, blood stasis and deficiency, and slow arrhythmia are intermingled deficiency. blood stasis and phlegm. Thus, they were treated respectively by clearing away heat, eliminating Yang and removing blood stasis, and warming Yang to remove blood stasis respectively. Results: The total effective rate was 96. 55% in 261 cases of rapid arrhythmia treated by modified Ding Xin Decoction, and 78. 46% in the control group with a significant difference between the two groups (P
6.Clinical observation on 31 cases of low pulse pressure syndrome treated with acupuncture at Neiguan (PC 6)
Peirun LI ; Hui WANG ; Jing GAO
Journal of Traditional Chinese Medicine 1993;0(04):-
To explore the effect of acupuncture at Neiguan (PC 6) on the cardiovascular functions in the patient with low pulse pressure syndrome. Methods: 49 cases were randomly divided into acupuncture group and medicine group. Acupuncture group was treated by acupuncture at bilateral Neiguan (PC 6) for 3 consecutive days, and the medicine group was given intravenous drip of Shenmai Injectio for 6 consecutive days. 20ml each day. Blood pressure, pulse pressure. SV, CO. LVWL, MAP, TPR. CCP, PAWP, BV, MHR and CMBV were examined before and after treatment. 23 healthy subjects were observed as controls. Results: The pulse pressure of patients before treatment was significantly lower than that of controls (P
7.Clinical Observation on High Colonic Lavement for Delaying Renal Failure in 98 Cases
Journal of Traditional Chinese Medicine 1992;0(11):-
Objective: To observe effect of combination of TCM-WM with high colonic lavement for delaying renal failure. Methods: 98 cases of renal failure at compensatory phase were randomly divided into a treatment group treated with high colonic lavement, twice each week. 2 hours each time, and a control group treated with oral administration of coated aldehyde oxystarch,10g each time, thrice each day, 3 months constituting one course. Results: After lavenment. symptoms were improved, deceaseing velosity of the clearance rate of endogenous creatinine in blood and urine slowed lowered, renal survival rate of kidney increased, and the interval of dialasis and other replacement therapy obviously postponed in the treatment group as compared with that before treatment and the control group. Conclusion: The high colonic lavement has obvious therapeutiv effect in delaying renal failure velosity with a smaller stimulation to the stomach and smal intestine. It is an effective way for conservation treatment of renal failure.
8.Effects of Luohuo Capsules on Dynamic Blood Pressure and Life Quality in the Patient of Hypertention
Xiangdong YU ; Wenquan ZHOU ; Ling CUI
Journal of Traditional Chinese Medicine 1992;0(12):-
0. 05). The treatment group in the improvement of most clinical symptoms were superior to the control group (P
9.Therapeutic Effects of Naolisu Instant Granules for Treatment of 60 Cases of Cerebral Apoplexy at Acute Stage
Journal of Traditional Chinese Medicine 1993;0(01):-
Objective: To observe clinical therapeutic effect of Naolisu Instant Granules for the patient of cerebral apoplexy at acute stage. Methods'. 90 cases were randomly divided into treatment group of 60 cases and control group of 30 cases. The treatment group was treated by oral administration of Naolisu Instant Granules and the control group was given Venoruton tablets, with oxygen inhalation, decreasing intracranial pressure, controlling blood pressure, preventing and treating infection, keeping water-electrolyte balance in the two groups. The changes of cumulative scores of TCM syndromes, cumulative scores of nerve function defect, and clinical therapeutic effects were compared between groups. Results: There were significant differences be- fore and after treatment in the changes of the cumulative score of TCM syndromes and the nervous function defect in the treatment group (P
10.Effects of Ganzhikang Capsule on Ultrastructure Changes in Non-Alcoholic Fatty Liver Rats
Journal of Traditional Chinese Medicine 1993;0(03):-
Objective: To observe effects of Ganzhikang Capsule on ultrastructures in non-alcoholic fatty liver model rats so as to provide morphological basis for clinical treatment. Methods: Fatty liver model rats were induced by high fat diet, and the effects of Ganzhikang Capsule on microstructures in liver tissue were investigated with Dong Bao Gan Tai used as control medicine. Results: In the model group, serious fatty degeneration of hepatocytes with inflammatory infiltration, degeneration and necrosis, and deforming, swelling of mitochondrion, dilatation of endoplasmic reticulum were found. After treatment of Ganzhikang Capsule, microstructures of hepatocytes restored obviously, fatty degeneration relieved significantly, and Ganzhikang Capsule was superior to Dong Bao Gan Tai in restoration of fatty degeneration (P