Recently, it has been done many phytochemical and pharmacological studies about raw tissues in TSP (Three seed prescription). The purpose of this study was to determine the effect of TSP on lipid peroxidation versus physiological antioxidants including SOD, GSH-Px and CAT in vitro in rat model with blood heat disease associated with “Three hot’. Compare to the control group MDA was significantly increased blood heat model. All three antioxidant ferments are clearly increased by “Three hot’. Also, it was noticed strong correlation between red cell aggregation index and MDA level. These results suggested, that “Three hot’I disturbed oxidant and antioxidant balance in blood heat models, which leads to red cell aggregation. On the basis of these results we conclude TSP could recover lipid peroxidation process by increasing antioxidant ferments

Introduction: This plants distributed about 2500 species in worldwide and 69 species of those grow in Mongolia. In case of medicinal application of this plant is commonly used traditional medicine in European and Asian. For example, the different preparations of Astragalus mongholicus root, the most commonly used Astragalus species in Chinese medicine. Other Astragalus species which are being investigated for their anti-cancer properties are the Turkish species, and include Astragalus brachypterus, Astragalus cephalotes, Astragalus microcephalus and Astragalus trojanus. Astragalus mongholicus.Bunge. Traditional Uses: The taste is sweet and the potency is hot. It is used for the following: treating light swelling, water swelling and phlegm, and improving physical energy and strength. It is also used to soothe a purulent inflammation, for wound-healing, to treat lung fever, oliguria and hemorrhoids. It is an ingredient of the following traditional prescription: Jurur-6 Chemical constituents: Root contains flavonoids: formononetin, 3-hydroxy-formononetin, 2,3- dihydroxy- 7,4-dimethoxyflavone, 7,3-dihydroxy-4-methoxyflavone 7-O- glucoside, 7,3-dihydroxy-4- dimethoxyflavone, saponins: astragaloside I-X, isoastragaloside I-IV, polysaccharides, Above- ground parts contain astragaloside quercetin, isorhamnetin, rhamnocetin, isorhamnetin 3-b-Dglucopyranoside, propingoside, coumarin, tannins, and saponins. Qualitative and quantitative assays: Flavonoids in the plant are identified by cyanidin reaction and reaction with lead tetraacetate. Total flavonoid content is determined by spectrophotometry at 430 nm and calculated as quercetin. Qualitative and quantitative standards: Loss on drying, 8.0%. Organic matter, not more than 0.5% and mineral matter, not more than 1.0%. Total flavonoid content, not less than 3.0%.

Introduction: Mongolian Traditional Medicine development has been rapid in recent years, so we need to pay attention on one part of treatment which is plant parts. It is a drug safety issue to standardize the traditional medicine. It is necessary to investigate biological active substances in plant, animal and mineral origin drug sources for the further evidence based usage of traditional recipe. Purpose: The determination of biological active substances in traditional “Suman mod-4” recipe. Methodology: To determine “Suman mod-4” (consist of Caesalpinia sappan L., Kaempferia galangal L., Daemonorops dracon Bl, Sal-Ammoniac) traditional medicine’s active constituents, by Chinese and Mongolian National Pharmacopeia (2012) were used thin layer chromatography (TLC) and high performance liquid chromatography (HPLC). Result: We developed optimal methodology for the identifying of biological active substances in “Suman mod-4” compound widely used in Mongolian traditional medical practice. And were determined biological active substance measurements in four samples of traditional recipe “Suman mod-4’ from different drug factories in Inner Mongolia. Conclusion: We determined amount of biological active substances in traditional “Suman mod-4” recipe: Bracial Caesalpinia sappan L tissue consist of 2.9847- 3.6716 mg/g, and B Caesalpinia sappan L tissue consist of 2.9214-3.4951 mg/g active ingredients respectively.

A diabetes is commensurate with the clinical symptoms to thirst disease of Mongolian traditional medicine when Jur ur-4 medicine is used. Jur ur – 4 is composed of Gardenia jasminoides Ellis., Vitis vinifera L., Coriandrum sativum L., and Gentiana acuta Michx. The aim of this study is to analyze components of Jur ur – 4 decoction by traditional methods. In addition, each components of taste, power and wisdom have compared to medicine indication. All of components have cool power and dispel bile heat. It has cool power and cure heat. The main components are Vitis vinifera L., and Coriandrum sativum L., cure thirst, Gardenia jasminoides Ellis., is being detoxification and Gentiana acuta Michx., is adjuvant that is used in bile heat for Jur ur-4 medicine.

According to the pharmacologic study, Agrimonia pilosa Ledeb contains chemical components namely agrimonin, agrimol C,F,G, agrimonolide, agrimophol, apigenin-7-O- glucoside, thalictiin , coumarin, tannin, sterin and quercetin. Agrimonia pilosa has been reported to possess cytotoxic, anti-oxidant, anti-tumor, antiviral, anti-microbial, anti-inflammatory, anthelmintic, anticoagulant and antiallergic activities. Agrimonia pilosa is mainly used for treatments of bloody discharge, urinary tract infections and sexually transmitted diseases, haemorrhoid, parasitic infections and skin disorders. In the future, we suggest that we have to conduct detailed pharmacological study on chemical components and effects of Agrimonia pilosa ldb (in vitro) based on the modern medical science as well as we have got an opportunity to produce new drug that can lead to new innovation.

The study goal was to determine efficiency of Antacid calcium-6 preparation to gastro-esophageal reflux disease by clinical study.The material and methods were randomized controlled trial.The study was 2 phased. In the first phase, participants are given Antacid Calcium-6 p.o, and then monitored gastric acidity by pH monitoring for 24 hours. We evaluated how to effect to reflux condition in before and after treatment by DeMeester index, G.A. Agafanova, A.P.Kholopov scores.The results are gastric minimum pH was 4.12±0.4, pH mean of 24 hours was 7.69±0.39, DeMeester index was decreased (p=0.001-0.005). These results are show Antacid calcium-6 decreases gastro-esophageal reflux. After taken preparation gastric pH become 4.62±1.54 was proven this preparation’s effect of to neutralize to gastric acidity. In the second phase, we compared between Antacid calcium-6 and Orgil mineral water by randomized comparative trial’s design and participants are filled GerQ form and performed gastro-esophageal flexible endoscopy in before and after treatment. Antacid calcium group people had changes of esophageal mucosa (88.2%), decreased ulcerative changes (52.9%) and improved gastritis (70%).In the Orgil mineral water group these changes were 63.3%, 33.3%, 29.6%. These results shown antacid calcium-6 is better than orgil mineral water to use treatment of GERD. In conclustion, antacid calcium-6 biological preparation has effect to neutralize enough in gastric acidity, and supports healing process in GERD.

Introduction: Nowadays, to correctly identify and use pharmaceutical raw materials, furthermore, to understand whether certain medicinal substances difference and to know possibility of replacement of foreign pharmaceutical materials with local pharmaceutical materials is becoming a facing problem. For those reasons, we took a textbook named “Beautiful eyes- Uzesgelent nuden chimeg” as a research material, knows as a masterpiece, composed by Jambaldorj, Mongolian famous scholar, originally held in Tibetan language. This textbook has names of pharmaceutical raw materials in Tibetan, Chinese, Mongolian and Sanskrit languages, contained methods to identify overall 879 raw materials and its growing locations, provided by 576 illustration figures. In our research, we used historical anthropology, historical comparative and hermeneutic methods. Result:In the “Beautiful eyes –Uzesgelent nuden chimeg”, wooden pharmaceutical raw materials were classified into 1.Root 2.Scion 3.Wood 4.Branch 5. Shoot 6. Bark 7. Pitch 8. Leaf9. Flower10.Seed and 98 species of raw materials used in medicine were explained in it. In order to make it effective, appearance of each raw material is illustrated by 2-5 figures, showing which parts are used for medicine. From 98 species of wooden raw materials, Jambaldorj had written 98 in Tibetan, 41 in Mongolian, 46 in Chinese, 42 in Manchu and only 14 in Sanskrit language. On the other hand, strength, growing locations and parts that used in medicine of 40 species of pharmaceutical raw materials were all described. By analyzing 27 objects that Jambaldorj had criticized as a mistake, we determined 20 of them were his right, 2 of them were inaccurate and 5 of them were required further investigations. Conclusion: Naiman toinJambaldorj’s work was valuable for identifying and using raw materials in past, but still valuable resource for research and correction. Thus, it is a clear evidence to identify Mongolian scholar’s contribution to traditional medicine.

Purpose:To identify theeffect of Antacid calcium-preparation on gastroeosophageal reflux disease by using pH meterfor 24 hour monitoring analysis. Study methodology:A randomly controlled test was used for the study. Study objects were administered Antacid calcium-6 preparation and their gastric acidity level was identified by pH monitoring analysis for 24 hours. Theimpact of preparation in regards with before and after treatment and their relationship were analysed by t-test. Results:The 24-hour pH meter analysis of Antacid calcium-6 preparation indicated that before administration of preparation the gastroeosophageal pH=5,75±0,14, which has increased after the administration to pH=9,7±0,02 and the average duration was 7,8±0,09 days. In other words, the alkalinizing effect was statistically significant (p<0.001). Also, According to the criteria developed by the DeMeester, the daily prevalence of reflux, the prevalence of reflux that continued for more than five minutes and the DeMeester index indicated that the preparation was significantly efficient (p=0.041). The neutrialising effect of the preparation was established by using the criteria method developed by G.A. Agafonova and A.P. Kholopov (1984), and after administering the preparation, the gastric level was pH=4,6±1,5 indicating that the preparation had a neutralising effect. The average duration for neutralization was 19,3±0,9 hours. Conclusion: Аntacid calcium-6 preparation was effective in neutralising the gastric acidity and it was appropriate for treatment of GERD, chronic gastritis.

Aim: To determine understanding about coffee consumption of teachers and develop proper food intake Methodology: Specially designed questionnaire with 9 items was filled by teachers who were chosen unexpectedly. Observation and interview was conducted too. Results: 85% of teachers said that they drink coffee with sugar and milk and it shows what they do not know about it increases adverse effects and deforms main quality of coffee. Consumption of teachers who works at universities and institutions is more that others when comparing with others. Most of teachers who works at universities said that coffee consumption is wrong activity. Consumption of teachers who works at universities and institutions is more that others when comparing with others. Mean age of coffee users is younger for teachers who work at secondary school. Secondary school teachers could not evaluate well actual dose of coffee when comparing with university teachers. Most of teachers do not know what additional sugar and milk increases adverse effects and deforms main quality of coffee. Possibility of coffee affection is more between secondary school teachers.