1.An investigation on the situation of hyperlipidemia of women aged fourty years of Hanoi Medical University
Journal of Medical Research 2001;16(3):7-12
The hyperlipidemia was usually found out in the community. It can result in some diseases as ischaemic heart disease, cerebralvascular disease, acute myocardial infarction. Some parameters of lipid were studied in women (total cholesterol, high density lipoprotein - cholesterol - HDLC, low density lipoprotein - cholesterol - HDLC, triglyceride and total lipid levels as compared to reference limit. 17 of 97 women had hyperlipidemia (7.39 +/- 3.1 mmol/l), 5 of them elevated total cholesterol (>6.3 mmol/l), 9 of them elevated triglyceride (>2.3 mmol/l) and 3 of them elevated l cholesterol.
Hyperlipidemia
;
Myocardial Infarction
2.Methemoglobin and treatment of hypermethemolobinemia
Journal of Medical Research 2002;18(2):61-65
The hyper-methemoglobinemia causes the oxygen transfer disorder. The clinical symptoms depends on the level of methemoylobinemia. Hypermethemoglobinemia can be congenital or acquired hypermethemoglobinemia. The congenital hypermethemoglobinemia caused by partial or total methemoglobine reeducates deficiency in patients with rare genetic heterozygous enzyme deficiency due to the abnormal hemoglobin. The acquired hypermethemoglobinemia occurred after exposure to colour compound, food and drinking water with nitrate or drugs. The determination of causative agent of hypermethemoglobin help treating more effectively
Methemoglobin
;
Hemoglobins, Abnormal
;
Therapeutics
;
Methemoglobinemia
3.Diagnostic of tuberculous meningitis of children by polymerase chain reaction (PCR)
Journal of Medical Research 1998;8(4):28-32
The PCR technique was used to identify ADN of M. Tuberculosis on cerebrospinal fluid samples in 44 tuberculous meningitis of children. The control group consists of other 21 meningitis (non Tuberculosis). The result showed that the PCR technique in finding M. Tuberculosis with the sensitivity is 68.2%, the negative predict value is 60%, the specificity and the positive predict value are all 100% respectively. The PCR result depended on patients who had been treated with tuberculosis drugs and had combined tuberculous injuries in the past. The PCR technique gives better results than other traditional M. Tuberculosis finding methods and even better than the ELISA technique
Polymerase Chain Reaction
;
Tuberculosis, Meningeal
4.The hormonal threshold area of menstruation
Journal of Medical Research 2000;12(2):44-49
Through studies on the hormonal threshold area of menstruation had shown that the hormonal threshold area of menstruation is not a right line but an area consisted of two limits, superior and inferior ones. Menstrual bleeding occurred only when the curve of hormonal effect on development of the endometrium is situated in this area of two limits. Above or under that threshold area the curve of hormonal effect on development does not cause endometrial hemorrhage. The author also showed that the superior limit has a mean value 57.65±43.36 pmol/L and the inferior one is at 29.27±19.43 pmol/L of estradiol. Basing on the above statement the author suggested that the menstruation may be defined as occurred when the curve of hormonal effect on endometrial development situates in a threshold area of menstrual bleeding and not when the sexual steroids go down under a certain threshold as earlier
Hormones
;
Menstruation
5.Nutritional therapy in chronic renal failure
Journal of Medical Research 1998;7(3):47-49
The selective low protein dietary in treatment of chronic renal failure aims at objectives in cluding reduction of symptom of hyperuremia and protection of function of rest normal kidney. However, the limitation of daily protein need will lead to lack of essential aminoacide. Use of ketoacid corresponding with aminoacid reduces the nitrogen supply, prevents the bad progress of chronic renal failure and limits the excessive filtration of glomerular, hyperphosphatemia and secondary increased para- thyroid function.
Kidney Failure, Chronic
;
diet therapy
6.The fourth bronchial pouch fistula and analysis of 20 cases
Journal of Medical Research 2000;13(3):3-8
The fourth bronchial pouch fistulae is the lesion of the fourth bronchial-pharyngeal duct in development of the embryo. 20 cases of this disease were diagnosed, operated and followed-up in the institute of ENT, from 1995 to 1997. 11 females and 9 males were affected; It manifested itself by recurrent episodes neck abscess, especially on the left side (95%). 13 fistulous tracts were found on operation with 86% of retrocartilaginous course.
Bronchial Fistula
;
Pouchitis
7.The role of transbronchial fine needle aspiration in the diagnosis of submucosal bronchogenic carcinoma
Journal of Medical Research 2002;18(2):7-12
Transbronchial needle aspiration in the diagnosis of submucosal bronchogenic carcinoma. Although exophytic endobronchial lesions can readily be diagnosed by forceps biopsy through the rigid bronchoscope. The lesion of submucosal or peribronchial by forceps biopsy difficult to diagnose by biopsy. The utility of transbronchial fine needle aspiration through rigid bronchoscope was made in 98 patients presenting with endoscopic abnormalities suggestive of submucosal bronchigenic carcinoma of respiratory department of Bachmai hospital from 3/1991 to 7/1996. Forceps biopsy was positive in 48 patients (58.77%). Transbronchial needle aspiration was positive in 88 patients (88.79%) and detected 6 cases additional carcinomas (who were treated by anti-tuberculosis of the lung). We concluded that TBNA significantly increases the yield, more effective than forceps biopsy alone in the detection of the infiltration of submucosal bronchogenic carcinoma.
suction
;
neoplasms
8.Immunohistochemical study of primary extranodal malignant non-Hodgkin's lymphoma
Journal of Medical Research 2000;13(3):20-23
Between 1996 and 1998, 31 cases of primary extranodal malignant non-Hodgkin's lymphoma were studied immunohistochemically. Immunohistochemical study showed that the majority of the cases were of B-cell type: 19 cases (73.07%) and only 3 cases (11.53%) were of the T-cell type. According to the Working Formulation system, the most common histologic type was diffuse, large cell type (61.29%). The histologic grade was moderate grade: 23 cases (74.19%), high grades: 5 cases (16.13%).
Immunohistochemistry
;
Lymphoma, Non-Hodgkin
9.Mobilization with granulocyte \ufffd?colony stimulating factor (G-CSF) and collection peripheral blood CD34 cells from healthy volunteer for allograft
Tung Quang Nguyen ; Tri Anh Nguyen ; Phan Trung Do
Journal of Medical Research 2007;47(1):13-19
Background: Peripheral blood stem cells are today the mains source of cells for transplantation. The number of CD34 in peripheral blood of adult healthy volunteers is very low, so we have to mobilize. Objectives: To apply a protocol to collect CD4 cells in peripheral blood of normal donors mobilized by using G-CSF. Subjects and method: G-CSF (Leukokin) at a dose 10 mcg/kg/day was injected subcutaneously in 5 consecutive days for mobilization CD34 from 5 healthy donors. Count the number of CD34 everyday and collect CD34 cells in 5th \ufffd?6th day by automated blood cell separator (COBE-Spectra), observed clinical and hematilogy, biochemistry symtoms spontaneously. Results: The number of CD34 harvested is 215,5 \ufffd?570,2 x 106 CD34/donor. Almost other of parameters of hematology and biochemistry of donors were normal after one week from the last separation. Conclusion: Mobilization with G-CSF and aphaeresis of periphral blood stem cell from normal donors is feasibility and safety. The number of CD34 can be to allograft for an adult patient.
Hematopoietic Stem Cells
;
Granulocyte Colony-Stimulating Factor
;
10.The preliminary report of occult HBV infection in Vietnamese
Truong Xuan Bui ; Bang Van Nguyen ; Phuong Minh Tran ; Trach Khanh Nguyen ; Quy Tran ; Yoshihiko Yano ; Yasushi Seo ; Yoshitake Hayashi
Journal of Medical Research 2007;47(1):28-32
Background: Vietnam is located in the endemic region of hepatitis B virus (HBV) infection, but no data of occult HBV infection was reported at present. Objectives: To investigate the prevalence of occult HBV infection in different ethnics of people and generations. Subjects and method: 80 voluteers with HbsAg negative from five different ethnics: Kinh, Tay, Mong, Giay and Dao in a Chino \ufffd?Vietnamses border province (Lao Cai) were enrolled in the study. After HBV-DNA was extracted, nested PCR of S gene and of Core-promoter/Pre-core region were used to detect HBV-DNA. Specifying nucleotide sequence was confirmed by direct sequencing. Results:The prevalence of occult HBV infection in population study was very high 73/80 (91,3%) by nested PCR of Core-promoter/Pre-core, significantly more sensitive than nested PCR of S gene (26,3%) (p<0,0001). The prevalence of occult HBV infection was notdifferent between ethnics of people or between children, adults. Conclusion: Occult HBV infection in Vietnamese is very common; however, nationwide further studies should be carried out to confirm this preliminary results and evaluate the impact of occult HBV infection in Vietnam.
Hepatitis B virus
;
Hepatitis B Surface Antigens
;