Malaria epidemiological stratification in ThuaThien-Hue province during the years 2003-2004 showed: There were 23 communes with 152 villages in malarial severious endemic areas; 17 communes and towns with115 villages and wards in moderate;9 communes and towns with 90 villages and wards in light; 6 communes and towns with 54 villages and wards in low malarial endemic; 95 communes and towns with 905 villages and wards in free malarial endemic areas. The stratification and interventions would help to develop a more appropriate and sustainable elements for malaria control
malaria ; epidemiology ; Intervention Studies

Malarial statistic data of at HungYen provincial Center of Preventive Medicine shown an incidence of 0,118% of population in the year 2001 and 0,08% in 2002, parasitic rate of 0,68% in 2001 and 0,49% in 2002. All clinical cases and parasitically confirmed cases were infected from the endemic areas , of South Vietnam. Malarial parasite was determined only on laboratories at the level of province and district. At basic level health stations, malarial patients and persons who arrived from endemic regions were not carefully managed
Malaria ; diagnosis ; Therapeutics ;

Surveillance carried out in the years 2002-2003 on malaria control microscope technician team at district hospitals and at microscope using sites of communal and intercommunal health stations in QuangBinh had reported that in the year 2003, 74 sites for microscope use were established in various malarial endemic regions. The rate of microscope using sites in communal stations and intercommunal polyclinics was the most. Errors rate which occurred generally at communal and intercommunal level was higher than at district level. For technicians, 62% had got good skills,28,9% rather good, 7,2% moderate and 1,5% bad in detecting the parasite, among them some had not good skill of maintaining microscope
Malaria ; Microscopy ; Therapeutics ;

In 1998-2002 year period, those studies were developed in LaoCai, LaiChau, QuangTri, Daklak, GiaLai and KonTum. Malarial patients with P. falciparum without complication were administered orally by a total dose of Chloroquine 25mg/kg in 3 day treating course or an unique dose of sulfadoxin-pyrimethamin.The use of medicines was observed and the parasitic density was monitored within 28 days after the treatment. Results showed the failure rate at almost studied locations
Malaria ; Therapeutics ; Pharmaceutical Preparations ; Malaria, Falciparum ; Drug Resistance ; Chloroquine ; Pyrimethamine

65 patients with uncomplicated Pl.falciparum malaria were monitored during 28 days after 5 -day -course use of artemisinine (year 1998) and 69 patients after 7 day course (year 2001). The mean fever cut time lengthened for 1,5 days in 1998 and 1,8 days in 2001.The mean parasite cut time had lengthened for 1,8 days in1998 and 2,3 days in 2001. The rate of reappearance of parasite accounted for 36,9% within 28 days follow up with 5 -day -course procedure and 7,3 % with 7 days procedure. The rate of repeated infestion was remarkable: 10/21 patients (year1998) and 3/5 (year 2001) had got recurrence. No change of EC50 was reported between the years 1998 and 2001, but an increase by 2 and 4 folds of EC90 and EC99 was reported.EC50,90 and 99% of chloroquine, mefloquine and quinine in the year 2001 decreased by 2 folds vs 1998
malaria ; malaria, falciparum ; Artemisinins ;

Acute toxicity of injectable doses of 40mg/kg, 80mg/kg, 120mg/kg, 160mg/kg of BB101 (trifluoromethyl hydroartemisinine) corresponding to 1/10,1/5, 1/4, 1/3 of LD50 by injection on monkey was studied. With the doses of 40mg/kg and 80mg/kg, on monkey, normal living activity was still manifested except anorexia, weight loss, hair fall...Bad conditions had been aggravating with the increasing doses. At the dose of 120mg/kg, monkey died 2 days after interruption of toxic substance and at the dose of 160mg/kg, monkey died on the day N5.As regards biochemistry indices, BB101 in 5 consecutive days with the daily dose of 40mg/kg and 80mg/kg enhanced SGOT, SGPT, proteine and creatinine (in permitted intervals);with 120mg/kg and 160mg/kg enhanced SGOT and SGPT by 3-5 folds higher, other indices were in permissible intervals. As regards hematological indices; white blood count, red blood count and haemoglobine reduced
toxicity ; Haplorhini ; animals ; Animal Experimentation

139 subjects of 2 ethnic groups of Kinh (Hanoi) and Muong (HoaBinh) were submitted to study from October to December 2003 in order to assess the sensitivity and the specificity of the rapid test of determination of G6PD. All subjects underwent both two methods (rapid test and quantifying method) in concomittance.Results showed the sensity of 91,2% and the specificity of 97,2% in both male and female genders. For detecting G6PD defiency in male, the rapid test gave higher sensitivity and specificity than in female 97,1 and 100% respectively in male and 85,3% and 94,1% in female subjects
Glucosephosphate Dehydrogenase ; deficiency ; diagnosis ;

This study was performed at Hanoi University of Natural Sciences and National Institute of Malaria and Parasitology from April 2001 to May 2002. Biological trials on laboratory strains of An. dirus were carried out according to WHO/VCB/81.806; WHO/CDS/CPC/MAL/98.12 and WHO/VCB/89.981. Analyses were conducted by the method of fluid-fluid extraction with the solvent system of n-hexan. Fendona 10SC,Icon 2,5CS,K-othrin ISC, Imperator 50EC .soaked mosquito bednet had manifested insecticide effect. Their effect of killing An.dirus was maintained for 5 -6 months. The procedure of analysis of pyrethroide compounds in use for soaking mosquito bednet was established and the half live of 125-188 day long period for each compound was determined
Pyrethrins ; metabolism ; world health organization ;

From Sept.2001 to Oct.2002, in diverse studied and control villages of 2 communes Iakor and Iatiem of ChuSe district, GiaLai province, an investigation was performed. In Iakor, 50mg/m2 solfac EW050 soaked mosquito bednets, and in Iatiem, 50mg/m2 solfac WP10 maintaining sprayed mosquito bednets were supplied for use. On the wooden or bamboo wall surface, insecticide effect was maintained for 6 months, on brick wall for 1month and on soaked net for 11 months. In the permanent resident sites of mosquitoes, no An. minimus and An.dirus, main vectors, were detected after the trial, but some other such as An.aconitus and An. jeyporiensis were still detected
Malaria ; Culicidae ; Insecticides

In May,Nov. and Dec. 2003, in some sites along HoChiMinh Road through QuangNam province including PhuocDuc commune of PhuocSon district;ThanhMy town of NamGiang district; Bhale commune of DongGiang district and through KonTum province, including DakMan commune, DakPek commune of DakGlei district, DakDuc commune of NgocHoi district...,an inquiry was carried out to determine the faune of arthropodes. 3297 samples of arthropode were collected.3 species of plea, 4 species of tick, 5 species of chigg and 46 species of Culicinae and 14 species of anophelinae mosquitoes were determined. They were distributed in 8 families, 2 classes -spider and insect. In almost sites, there are various arthropode species as pathological factors
parasitology ; Arthropods ; epidemiology