In recent years, the incidence of obesity has been rapidly increasing, greatly elevating the incidence of hypertension, heart disease, non-alcoholic fatty liver disease, and other diseases. Reducing the incidence of obesity has become the focus of global concern. There is an urgent need to find effective and safe treatment method. More and more evidence support the efficacy of auricular acupoint therapy for obesity. It has the advantages of safety, effectiveness, convenience, and cheap. This article intends to discuss the research status of auricular acupoint therapy for obesity based on theoretical development, mechanism exploration, and technical innovation in order to promote the clinical application of auricular acupoint therapy for obesity. At present, with the help of multiple disciplines, inheriting and enriching the theoretical connotation of auricular point therapy for obesity, confirming its clinical effectiveness and safety, clarifying its effect mechanism in the treatment of obesity, and improving the traditional auricular acupoint therapy are feasible directions to promote auricular point therapy in the treatment of obesity, and it can make auricular point therapy have a broader application prospect.

With the integration and application of various disciplines, traditional Chinese medicine′s auricular acupoint therapy has gained new opportunities for development. The effective activation of auricular acupoints is crucial as the initial step in auricular acupoint therapy. To address this issue, advanced techniques for physical stimulation, blending principles from traditional Chinese and Western medicine, have been developed. This paper explores the profound impact of magnetism on the structure and function of organisms from multiple dimensions, focusing on magnetobiology. It provides a comprehensive review of the clinical efficacy, research paradigm, challenges, and future prospects of auricular magnetic therapy. The article emphasizes the magnetic characteristics of organisms, particularly the nervous system′s high sensitivity to magnetic fields. It highlights the potential of modern magnetic stimulation techniques in treating brain diseases through auricular therapy. Additionally, the paper explores the research paradigm of auricular magnetic stimulation in conjunction with physical molecular dynamics simulation, materials engineering, mathematical modeling, and interdisciplinary biomedical technology. This endeavor is expected to provide valuable insights for optimizing the parameters of auricular magnetic stimulation and understanding its underlying principles. The multidisciplinary, cross-system, and multi-scale biophysical research paradigm introduces a new conceptual framework and investigative approach for auricular acupoint therapy, significantly enhancing the safety and efficacy of auricular magnetic stimulation therapy.

This article employs a multidisciplinary approach encompassing traditional Chinese medicine, history, philology, and exegetics to comprehensively examine the historical evolution of auricular acupoint therapy and otomedicine. Originating in China, systematized in Europe, and currently advancing through modern research and development led by China, this study traces the historical context of otological practices. It outlines the foundational principles of otomedicine as depicted in the Huangdi Neijing, elucidates the accumulation of ancient otomedical knowledge within this framework, reviews the systematic establishment and theoretical underpinnings of auricular acupoints, and delineates the process of formulating auricular acupoint standards. Through case studies such as " ear-brain interconnection" and " ear treatment of encephalopathy", it illustrates the interdisciplinary nature of ear medicine research and development. The article aims to illuminate the historical transition from ear therapy to ear medicine within the contemporary context and the emergence of auricular point-guided ear medicine. By drawing on historical insights and looking toward the future, it provides a foundation for the ongoing development of the ear medical specialty, offering insights for integrating non-drug therapies into China′s healthcare system and global health initiatives.

The rapid advancement of informatization has opened up new possibilities for the development of auricular acupoint information devices. This paper starts with a discussion between diagnosis and treatment of auricular acupoint and auricular acupoint information devices. It also summarizes the current research and development status of auricular acupoint information devices that assist with precise acupoint localization, diagnosis, and treatment. Furthermore, it explores the impact of these devices on transforming the models of diagnosis and treatment, as well as facilitating telemedicine in auricular acupoint. The analysis highlights existing challenges faced by auricular acupoint information devices globally, such as limited clinical application and promotion, the urgent need for improved level of informatization, and insufficient cross-disciplinary integration. The paper also proposes corresponding measures that emphasize the importance of research, development, and transformation, enhancing the level of informatization, and fostering multidisciplinary exchanges and cooperation. The aim of this study is to provide valuable insights for the development of auricular acupoint information devices.

Glycyrrhizae Radix et Rhizoma is the most commonly used herb in ZHANG Zhongjing′s Treatise on Cold Pathogenic Diseases and Synopsis of Golden Chamber. It serves as a crucial entry point for understanding ZHANG Zhongjing′s prescription system. The role of Glycyrrhizae Radix et Rhizoma in ZHANG Zhongjing′s prescription system differs from its current recognized efficacy. By analyzing the typhoid prescriptions and referring to ancient materia medica texts from various dynasties, this study categorizes the formulas containing Glycyrrhizae Radix et Rhizoma and identifies four fundamental efficacies associated with it: fluid retention, preservation of gastric qi, support of yang qi, and protection of the triple energizer. These basic efficacy principles align with the core treatment principles implied in ZHANG Zhongjing′s prescription system, suggesting that Glycyrrhizae Radix et Rhizoma is one of the key herbs in constructing ZHANG Zhongjing′s prescription system. To elucidate the logical expansion of prescriptions, formulas containing Glycyrrhizae Radix et Rhizoma are deconstructed and classified into first-order, second-order, tertiary-order, quaternary-order, and other formulas based on the affinity of the paired herbs. Similarly, the corresponding herbs are classified accordingly. Using Cinnamomi Ramulus, Zingiberis Rhizoma, Paeonia lactiflora Pall., and Ephedrae Herba as examples, the study analyzes the principles behind formulas containing Glycyrrhizae Radix et Rhizoma. ZHANG Zhongjing′s prescription system strategically added or subtracted other herbs to fully utilize or extend the four fundamental effects of Glycyrrhizae Radix et Rhizoma, resulting in the majority of existing formulas through continuous expansion. This provides new insights and approaches for further in-depth study of ZHANG Zhongjing′s prescription system.

In the theoretical system of traditional Chinese medicine (TCM), the theory of " homogeny" is rich in content and has been extensively discussed by medical scholars throughout history. Various relationships, such as " homogeny of liver and kidney", " homogeny of blood and water", and " homology of ying and wei", have been explored. One relationship that is particularly relevant to the theoretical system of TCM is the connection between dryness and dampness, which is associated with the pathogenesis of many modern diseases. Understanding the relationship between dryness and dampness is crucial in clinical practice. This article examines relevant literature, including classic works like the Huangdi Neijing to explore the theoretical basis for the concept of " homogeny of dryness and dampness". The core connotation of this theory includes the ideas that dryness can generate dampness and dampness can transform into dryness. In clinical practice, it is important for doctors to apply this theory flexibly, addressing dampness when dryness is present and vice versa. For diseases characterized by dampness or dryness pathogens, doctors should consider the coexistence, homology, and mutual transformation of dampness and dryness when conducting syndrome differentiation and treatment. The theory of " homogeny of dryness and dampness" not only enhances the understanding of the etiology and pathogenesis of TCM, but also provides valuable theoretical guidance for modern clinical practice. Further research on this theory will continue to highlight its value in modern clinical applications.

In the context of the complex and ever-changing spectrum of diseases, the traditional Chinese medicine compatibility of prescription and drugs is no longer able to fully meet the needs of clinical diagnosis and treatment. Therefore, this article is based on the diagnosis and treatment model of the combination of disease, syndrome, and symptom, combined with the development achievements of Western medicine, and explores the principles of formulating traditional prescriptions based on the combination of chief, deputy, assistant, and envoy. This article proposes a formulation principle of composing prescriptions with the diagnosis of syndrome as the chief, the diagnosis of disease as the deputy, the treatment of symptoms as the assistant, and the harmonization of medicine as the envoy. This forms a treatment plan with the core link of syndrome differentiation and treatment, disease differentiation and treatment, symptomatic treatment, detoxification, and efficacy enhancement. The purpose of this article is to address the current clinical challenges such as an increasing disease spectrum and the complexity of syndrome patterns and symptom clusters. It aims to provide new insights into traditional Chinese medicine clinical treatment plans and herbal formulation strategies, with the ultimate goal of improving the clinical effectiveness of traditional Chinese medicine.

To date, there are four critical challenges currently present in traditional Chinese medicine psychiatry: inconsistency in guiding theory, limitations in disease nomenclature, inapplicability of the syndrome differentiation and treatment model of internal medicine somatic symptoms to psychiatry, and need for improved clinical treatment efficacy. This study follows the guiding principle of syndrome differentiation and treatment that focuses on "identifying core prescriptions based on core symptoms and pathogenesis", by using psychiatric symptoms from Western psychiatry as the core symptoms for differentiation and treatment, and by applying the refined five spiritual zang viscera theory to qualitatively and locationally assess psychiatric symptoms, this approach establishes the core pathogenesis and corresponding treatment methods for common psychiatric disorders. Specifically, the core pathogenesis of schizophrenia is identified as "kidney deficiency with liver hyperactivity", treated by tonifying kidney and tranquilizing liver; for depression, the core pathogenesis is "yang qi stagnation", treated by ascending yang and relieving stagnation; for bipolar affective disorder, the core pathogenesis is "excess metal with latent fire", treated by nourishing yin and regulating yang; for anxiety disorder, the core pathogenesis is "kidney deficiency with hyperactivity of the will", treated by tonifying kidney and calming anxiety; for tic disorder, the core pathogenesis is "kidney deficiency with liver wind", treated by tonifying kidney and suppressing hyperactive liver for calming endogenous wind; for attention deficit hyperactivity disorder, the core pathogenesis is "kidney will deficiency with heart spirit imbalance", treated by nourishing kidney and enhancing will for storing the spirit; and for autism, the core pathogenesis is "kidney deficiency with weak spirit", treated by nourishing kidney and strengthening heart for benefiting spirit. Based on clinical evidence and the identified core pathogenesis, core herbal prescriptions for treating common psychiatric disorders are established, thereby constructing a syndrome differentiation and treatment system for psychiatric symptoms based on the five spiritual zang viscera theory.

Post-stroke depression is a common complication after a stroke. Based on the theory of ＂deficiency of heart qi leading to sadness＂recorded in Huangdi Neijing, our team proposes that deficiency of heart qi is the basic pathogenesis of post-stroke depression, with sadness being its main manifestation. Therefore, we advocate treating post-stroke depression from the perspective of the heart, and clinically, it can be divided into four stages: heart-liver stage, heart-lung stage, heart-spleen stage, and heart-kidney stage. Treating post-stroke depression with the principle of regulating qi and nourishing the heart, patients in the heart-liver and heart-lung stages are mainly middle-aged and young adults, with a pathological nature of qi stagnation and mild deficiency of heart qi, and therefore, the method of promoting the flow of meridians and regulating qi should be adopted. In contrast, patients in the heart-spleen and heart-kidney stages are mainly middle-aged and elderly, with a pathological nature of qi deficiency and severe deficiency of heart qi, and therefore, nourishment and tonification should be prioritized. In response to the above four stages, our team has achieved good clinical efficacy by administering Xiaoyao Powder, Baihe Dihuang Decoction, Ganmai Dazao Decoction and Jingui Shenqi Pill respectively. This study discusses the approach to treating post-stroke depression from the perspective of a "deficiency of heart qi leading to sadness" by examining three aspects: the theoretical basis of Chinese and Western medicine to treat post-stroke depression from the heart, the basic pathogenesis and staging of post-stroke depression, and the treatment principle of regulating qi and nourishing the heart. The study also briefly analyzes the clinical experience of the medications used for this condition to provide a reference for the treatment of post-stroke depression.

To clarify the reasons for the phenomenon of producing different viewpoints in the theory of Huangdi Neijing and how to understand and apply these different viewpoints correctly. This study explores the founding basis of the characteristics of "viewpoint integration" in the theory system of Huangdi Neijing and explains the theoretical significance and clinical value of "viewpoint integration" from the perspective of the core concept of Huangdi Neijing. In conclusion, when grasping the characteristics of "viewpoint integration" in Huangdi Neijing, thinking about, recognizing, analyzing, and solving problems is the main line and the core. Understanding different points of view should be extensive and in-depth. Do not use one viewpoint to understand all viewpoints, do not use one viewpoint to explain another viewpoint, and do not mechanically mix two viewpoints. At the same time, it is necessary to clarify the construction process of different viewpoints and to learn to grasp these viewpoints from different angles. Studying the characteristics of "viewpoint integration" in Huangdi Neijing can not only better understand the theoretical content of Huangdi Neijing, but can also help open up ideas for the diagnosis and treatment of diseases, develop and innovate the theory of traditional Chinese medicine, and improve clinical efficacy.