1.Clinical and imaging features of delayed intracerbral hematomas after head injury
Journal Ho Chi Minh Medical 2004;8(1):48-52
A prospectively study were conducted in 77 cases of delayed intracranial hematomas after head injury (male 59 cases, female 18 cases, aged from 17-60) in the Neurosurgery Department of Cho Ray Hospital from October 2001 to August 2002. The mainly reason of admission was traffic accident. Methods of surgery were wide decompressive craniotomy and removal of hematoma without bone flap. The results: good outcomes: 62 cases, moderate outcomes: 9 cases, death: 6 cases, reoperation: 3 cases. The development of intracerebral hematomas after head injury is very complex. It can occur immediately after injury or delay although initial CT scan is normal or shows slight contusion. Therefore, the doctors must examine closely head injuries to find out delayed intracerebral hematomas for prompt operation to lessen later sequellas and mortality
diagnosis
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Hematoma
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Craniocerebral Trauma
2.Naltrexone and cognitive behavior therapy - an effective solution for relapse prevention
Journal Ho Chi Minh Medical 2004;8(1):52-57
An uncontrolled clinical trial was conducted to investigate the effect of Naltrexone and Cognitive Behavioral Therapy (CBT) on relapse prevention in Green Center, Hochiminh city from October 2002 to August 2003. The sample included 106 addicts (94.3% males) who just passed the acute detoxification process. Patients came to the Green Center 3 times per week (every other day), took 100 mg Naltrexone (150mg on weekend) at the Center, and then got a CBT session in one hour. The Naltrexone-CBT program was prolonged in 6 months. The results: 65/106 (61.3%) patients have terminated the treatment course, in which, only 4 patients (6.2%) followed the whole program (6 months); 7 patients (10.8%) have followed 3 - 6 months. The average of treatment duration was 56.7 51.8 days. There were 29.2% addicts have relapsed, in which the relapse rate of addicts, who have followed the whole program in 6 months was 0%; of addicts who had the treatment duration from 3 – 6 months was 5.3%; and of addicts with the treatment duration less than 2 months was 89.4%. The main recognized reasons for the great drop-out rate were the familial interference which a tendency of shortening the treatment course just after 3 months abstinence of their offspring (27.7%), the high cost of the treatment in comparison to the average income of most people (18.5%), the treatment center is too far from addicts home (16.9%)
Naltrexone
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Cognitive Therapy
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prevention & control
3.Detection of meningeal bacteris in cerebrospinal fluid by multiplex PCR
Journal Ho Chi Minh Medical 2004;8(1):58-61
Semi-nested multiplex PCR was used for rapid detection of Haemophilus influenzae, Niesseria meningitidis bacterials and streptococci in cerebrospinal fluid of suspect purulent meningitis patients. The method based on bacterial 16SrRNA gene amplification to be in all bacteria. With high specificity and sensitivity, the method had a detection limit of 10o CFU/ml on S.pneumoniae culture. Tested on 49 cerebrospinal fluid samples, the method detected 14/15 infected samples, in which 3 cases were infected with bacteria other than those investigated
Polymerase Chain Reaction
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diagnosis
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Bacteria
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cerebrospinal fluid
4.Treatment of avascular necrosis of femoral head with vascular pedicle iliac crest grafting
Journal Ho Chi Minh Medical 2004;8(1):84-88
20 patiens avascular necrosis of femoral hip had been treated with vascular pedicle iliac crest grafting same side from 11/2002 - 1/2004. Follow up, longest is 52 weeks, the earliest is 12 weeks. Average age was 38,5. Presumed risk factors were excessive use of alcohol (14/20), the use of corticosteroid prolong (3/20), no specific (3/20). 18 good result patients, 2 not good result patients (both in Ficat IV before operation). None infection, inguinal hernia and limit range of motion of hip. One patient had weak quadriceps (the complete recover after 6 weeks). 10 loss sensation lateral thigh (back normal after average 2 weeks). 2 loss sensation in thigh (back normal after average 2 weeks)
Osteonecrosis
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Therapeutics
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transplantation
5.Treatment of avascular necrosis of the femoral head in adult using free vascularized fibular graft
Journal Ho Chi Minh Medical 2004;8(2):88-93
From 11/1998 to 3/2002 have used 12 free vascularized fibular grafts for 12 fermoral heads of 10 patients including 2 stage II, 7 stage III and 3 stage IV. The youngest is 28, the oldest is 59. Longest follow-up duration is 5 years, the shortest being 21 months, average is 42 months. The 4 very good function, 1 good, 5 moderate. 7 femoral heads remain the same stage, 5 heads change to the after Marcus. No body asks for total hip replacement. Free vascularized fibular grafts can improve the function, delay the progress of necrosis and elongate the time of use of the femoral head
Osteonecrosis
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Therapeutics
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transplantation
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Adult
6.The use of carbon composite plate for the femoral shalt fracture fixation
Journal Ho Chi Minh Medical 2004;8(2):93-99
Since January 2001, in Cho ray hospital, 80 patients with 81 femoral fractures were osteosynthesized with carbon composite plate produced in Viet Nam. 67 men, 13 woman, average age was 29,5. 77 cases of bone healing win 95,01%. Early function restoration and complete is 66 cases (81,5%). The biological complication have 3 cases of infection (3,7%). The mechanical complication have 2 cases of re-fracture (2,46%) and 1 case of edge break
Fracture Fixation
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Carbon
7.The correlation coefficient of NK population's percentage in healthy adults donors gained by standard method and estimate methods
Journal Ho Chi Minh Medical 2004;8(2):99-103
The samples obtained from the 25 healthy adults donors, from19 to 50 years old of age, 18 men and 7 woman. Different antibodies match different methods. Standard method: CD3 (FITC) / CD16, CD56 (PE) / CD45 (PerCP) / CD19 (APC) mixture of antibodies. Estimate method: 3 colors use CD4 (FITC) / CD3 (PE) / CD8 (PerCP) mixture of antibodies and 4 colors use CD3 (FITC) / CD8 (PE) / CD45 (PerCD) / CD4 (APC) mixture of antibodies. Results: standard method - estimate method 3 colors: r = 0,85; % NK (adjust) = 1,99 x % NK (estimated) + 2,31; standard method - estimate method 4 colors: r = 0,85; % NK (adjust) = 1,63 x % NK (estimated) + 4,53
Tissue Donors
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methods
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Reference Standards
8.Investigation of point mutations in pbp1a gene of streptococcus pneumoniae resistant strains by PCR-SSCP-sequencing
Journal Ho Chi Minh Medical 2004;8(2):103-107
Study used the methods of PCR-SSCP-sequencing to detect and identify point mutations in pbp1a gene, one of the genes involved in penicillin resistance of streptococcus pneuminiae. SSCP analysis result of PCR products from 19 clinical resistant and 1 susceptible strains allowed their classification into defferent groups depending on their electrophoretic pattern. This classification fits results obtained by sequencing. With improvement in the resolution capacity of SSCP, these methods could be used efficiently to investigate penicillin resistance in streptococcus pneuminiae
Streptococcus pneumoniae
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Mutation
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Genes
9.Stressful factors associated with recurrent abdominal pain among junior high school children in district 1, HoChiMinh city
Journal Ho Chi Minh Medical 2004;8(2):108-112
Cross-sectional study conducted among 1026 schoolchildren selected from all 9 junior high schools in district 1, Hochiminh City. Recurrent abdominal pain (RAP) rate was 4,2%. Female schoolchildren were more likely to develop RAP than male. Stressful factors associated with RAP were frequently scolded by parents (49,9%), 29,6% frequent sibling quarreling, 29,5% move to new school in the year, 3,7% birth of a sibling in the year. 12,6% schoolchildren were serious diseases. 31,3% schoolchildren were hospitalized
Life Change Events
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Abdominal Pain
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child
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Schools
10.Ovarian cancer: pathological characteristics
Journal Ho Chi Minh Medical 2004;8(2):113-117
Research at Tu du hospital from 1998 to 2004 on 212 ovarian tumors with 48 ovarian cancers, from 16 to 82 years of age. Anapathology result: epithelial tumors (72,91%) are the most common with serious and mucinous cystadenocarcinomas; germ cell tumors (18,75%) had the second rank composed mainly of mixed germ cell tumors, endodermal sinus tumors and immature teratomas. 3 cases of genital stromatic tumor include all granuloma
One case of krukenberg tumors. During the period 1998 to 2000, 50% of ovarian cancers are detected at an early stage I and II. This proportion has increased to 58% in the period from 2002 to 2004
Ovarian Neoplasms
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diagnosis
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epidemiology