1.Impact of low-protein diet supplemented with ketoacids and anemia treatment with r-HuEPO in the conservative treatment of chronic renal failure
Journal Ho Chi Minh Medical 2005;9(1):17-21
The study was carrried out on 30 patients with chronic renal failure due to different causes with creatinin clearance of 14± 5.5ml/min. Results: in 17 cases, serum creatinine of 6.4mg% before treatment decreased to 4.2mg% after treatment (P<0.005). Average serum protein of 6.5mg% before treatment increased to 7.02mg% after treatment (P<0.005). Average serum creatinine level didn’t change after treatment (5.4mg% versus 5.3mg%) in 8 cases, along with average serum protein level of 7.1g% before treatment decreased to 6.8g% after treatment in 8 cases. In this group, there was one death due to falling down from the staircase but consequence of treatment. In two groups, average Hb and Hct of 7.8g% and 25% before treatment increased to 11.1g% and 32.1% after treatment
Kidney Failure, Chronic
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Therapeutics
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Anemia
2.Study of using mitomycine in the prevention of adhesion formation affter endoscopic sinus surgery
Journal Ho Chi Minh Medical 2005;9(1):22-25
A prospective study was carried out on 32 patients in order to assess effect of mitomycine C in the prevention of adhesion formation after endoscopic sinus surgery on high-risk patients. The risk factors of post-operative adhesion included narrow nasal passages (9%), recurrent sinusitis with obstructive scar (22%). 88% mucous membrane was normal 6 months after surgery, 6% was mild adhesion after surgery. Results: administration of mitomycine C 0,04mg on the surface of sinus mucous membrane within 4 minutes, it showed high effectiveness of post-operative anti-adhesion in high-risk patients. There wasn’t any complication
Sinusitis
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Endoscopy
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Surgery
3.Perineal canal in children with normal anus: epidemiology, clinical and treatment
Journal Ho Chi Minh Medical 2005;9(1):25-30
A prospective study was carried out on 120 perineal canal patients with normal anus who were treated at Pediatric Hospital, Ho Chi Minh City from September 1999 to August 2003. Patients were divided into group I: active inflammation, group II: vulvar excoriation, group III: no inflammation. Group I and II were treated medically until no more inflammation. The fistula was closed by the Tsuchida’s technique. Results: there were 2 patients healed spontaneously after internal treatment and 118 patients were closed fistula, among them there were 90 cases without colostomy and 28 with colostomy. There were 72 patients in group I, 12 in group II, and 34 in group III. Recurrence occurred in three cases without colostomy and one case with colostomy. One among these 3 without colostomy and the only one with colostomy were treated again with good result by the same procedure
Anal Canal
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Child
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Diagnosis
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Therapeutics
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Epidemiology
4.Clinical significance of tests in diagnosis of HCV
Journal Ho Chi Minh Medical 2005;9(1):30-34
Study on 169 patients (87males, 82 females) aged from 21 to 71 years old in order to determine, quantify as well as type hepatitis C virus. Immunoassay was used to detect anti HCV and serotype of HCV from patients’ sera; molecular biology assay was used to detect HCV-RNA (using RT-PCR target the 5’UT region of viral genome), and to quantify the HCV in the patients’ blood (using bDNA). Results: the rate positive HCV-RNA were 70% among 319 cases with anti HCV (+). In 169 cases that have been done serotype tests, the most common serotypes were type 6 (44.38%), followed by type 1 (37.28%). Type 1 is referred as the most difficult to response to the specific treatment. The results of quantitative assay showed that type 1 and type 6 infected patients had high quantity of viremia. From this study, the roles of the molecular biology assays were defined as the very necessary in diagnosis as well as treatment of patients with HCV infection
Hepacivirus
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Diagnosis
5.Investigation of lactic acid bacteria’s abilities of transfering the anti-antibiotic gene by conjugation
Journal Ho Chi Minh Medical 2005;9(1):35-38
Isolate, purify, and identify bacteria from probiotic supplement. Results: 5 strains of lactic bacteria were determined, including: Steptococus feacalis; Streptococcus lactic; Bifidobacterium bifidum; Lactobaccillus acidophilus; Lactobacillus casei. Study the sensitivity of these bacteria with antibiotics, results showed that these bacteria were resistant to many antibiotics, especially oral antibiotics. Conjugative trial between Streptoccocus feacalis, Streptococus lactic, Bifidobacterium bifidum, lactobacillus acidophilus casei and E.coli K12, and conjugative trial of lactic bacteria together showed negative results. Therefore, probiotic product contained many lactic bacteria can be used concomitant with some oral antibiotics to prevent or treat digestive disorders
Anti-Bacterial Agents
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Bacteria
6.Non-Hodgkin lymphomas recurrence in central nervous system
Journal Ho Chi Minh Medical 2005;9(1):38-43
A retrospective study was carried out on 32 patients with non Hodgkin lymphomas (NHL) in order to evaluate incidence rate, outcome and risk factors of central nervous system (CNS) recurrence. The results showed that: 1 patient had general manifestation and local CNS symptoms, 3 patients had CNS recurrence later on. The cumulative risk of CNS recurrence in 4 years was 19%. The CNS recurrence risk was 39% in high grade NHL, occurring usually in the first 14months, 22% in moderate grade NHL, occurring usually in the first 6 years and 7% in low grade NHL with higher degree of malignancy. In multi value analysis, NHL with high and moderate grades were independent risk factors for CNS recurrence. There are no clear evidences about role of CNS prophylaxis in patients with moderate and high grade of NHL. The survival time is 1-2 months
Lymphoma, Non-Hodgkin
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Central Nervous System
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Nervous System
7.Brain abscess surgical treatment
Journal Ho Chi Minh Medical 2005;9(1):43-48
A retrospective study was carried out on 120 patients with brain abscess treated at Cho Ray Hospital from Oct 2000 to Feb 2003. 91% patients were hospitalized on emergency. The patients were diagnosed easily and quickly brain abscess by CT. 80 patients (70.8%) underwent emergency surgeries and the commonest applied technique (73.3%) was punction and pus drainage. Antibiotic were indicated suitably for patients, corticoids were prescribed for 31.6% patients with severe brain edema, antiepileptic drugs were given for patients with convulsions. Twelve patients (10%) died because of too late hospitalizations with general complications and/or brain hernia. Patients with brain abscess were commonly arrived late; the majority of them were admitted on emergency. Although having CT for accurate diagnosis and surgery and new antibiotic generations, the mortality rate is still high
Brain Abscess
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Therapeutics
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Surgery
8.Establishment PCR-based protocol for the detection of human papilloma virus in vaginal swab specimens
Journal Ho Chi Minh Medical 2005;9(1):49-53
The authors reported a PCR-based protocol for the detection of Human papilloma virus in vaginal swab speci
Papilloma
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Papilloma/virology
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Diagnosis
9.Transrectal ultrasonography and prostate biopsy
Journal Ho Chi Minh Medical 2005;9(2):65-67
Transrectal ultrasonography (TRUS) in prostate cancer could show the images of multiform prostate adenomas. Specific sign is a hypoechoic area in periphery of gland. Overall, sensitivity (32%) and specificity (51%) of TRUS in diagnosis prostate cancer weren’t high. The false negative was from 30% to 40%. Two major roles of TRUS were to determine suspected lesions and to increase accuracy of prostate biopsy. TRUS techniques in diagnosis prostate cancer were: conventional TRUS, TRUS with Doppler, TRUS with contrast Doppler, and TRUS with 3D ultrasound. Under TRUS-guiding, biopsy can be performed through perineum or rectum
Prostate
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Biopsy
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Ultrasonography
10.Gastrointestinal stromal tumors
Journal Ho Chi Minh Medical 2005;9(2):68-73
Gastrointestinal Stromal Tumor (GIST) is uncommon disease with only about 3,000 to 6,000 cases diagnosed annually. Tumors can occur in any sites in gastrointestinal tract, especially in stomach (60-70%) and small intestine (20-30%) and in large intestine and oesophagus, sometime in omentum, mesenterium, behind peritonaeum, etc. The disease is common in male from 40 to 80 years old. GIST is detected randomly during examinations such as endoscopy, X-ray or CT scan of stomach, large intestine. Tumors have two kinds of cell: lozenge cell (70%) and epithelial cell (30%). GIST is divided into 4 stages. Each stage has suitable treatments as chemical therapy, radio therapy, and targeted therapy. For metastatic GIST, tumors can be removed by surgery. The 5 years survival rate is 34% in removal tumors and is 10% in remained tumors
Gastrointestinal Stromal Tumors
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Diagnosis