1.Evaluation the effect of pantoprazole, amoxicillin and clarithromycin (PAC500) in the treatment of gastric and duodenal ulcer patients with H.pylori infection
Journal Ho Chi Minh Medical 2004;8(4):204-209
Therapeutics; Helicobacter pylori; Duodenal Ulcer; Stomach Ulcer; Pharmaceutical Preparations; 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Clarithromycin
Study on the effect of PAC500 regimen in the treatment of peptic ulcer disease with H. pylori (+) in 33 patients. The results showed that, this regimen is good with the mean value of pain relief is 6.5 days in addition to the high percentage of ulcer healing (96.9%: protocol and 93.9%: intention of treatment) and the high percentage of H.pylori eradication (87.5%: protocol and 84.8%: intention of treatment). Beside, there is an improvement of the acute gastritis lesion on gastric mucosa after the eradication. But the high percentage of side-effects (81.8%) must be considered, bitter sensation of the mouth is the most common and can be tolerated. Reported only 1 case had to withdraw this trial because of vomitting side-effect
Therapeutics
;
Helicobacter pylori
;
Duodenal Ulcer
;
Stomach Ulcer
;
Pharmaceutical Preparations
;
2-Pyridinylmethylsulfinylbenzimidazoles
;
Amoxicillin
;
Clarithromycin
2.Study on acute oral toxicity of the seed of momordica cochinchinensis
Journal Ho Chi Minh Medical 2004;8(4):209-211
The trial of acute oral toxicity of the seed of Momordica cochinchinensis in mice showed that LD50 of the seed powder is 92.27g/kg. The result of the study should be considered in the attempt to use the seed of Momordica cochinchinensis as a drug administered orally. While waiting for confirmation, it is necessary to inform in public that taking this seed orally should be avoided
toxicity
;
Mouth
;
seeds
3.P53 and MDM2 overexpression in oral cancer in Vietnamese
Journal Ho Chi Minh Medical 2004;8(4):212-215
The previous study detected 15/18 cases of oral squamous cell carcinoma expressing p53 positive immunostaining: 7/8 cases with p53 mutation and 8/10 cases without p53 mutation. In this study, immunohistochemical staining showed mdm2 overexpresion in 7/18 cases, combined p53/mdm2 overexpression in 6/18 cases, mdm2 overexpression in 5/8 p53-positive without mutation cases. These results indicated that p53 overexpression can be associated with p53 gene mutation, as well as mdm2 overexpression in the oral carcinogenensis
Mouth Neoplasms
;
diagnosis
;
Genes, p53
;
Proto-Oncogene Proteins c-mdm2
4.Immunohistochemical analysis of estrogen and progesteron receptors in breast cancer
Journal Ho Chi Minh Medical 2004;8(4):216-221
Estrogen and progesteron receptor status of 600 cases of breast carcinoma treated in Hochiminh City Cancer Center were studied by immunohistochemical staining technique. 66.8% of cases were positive for estrogen and/or progesteron. The expression of estrogen and progesteron correlated with groups of age, menopausal status and histological grades. The rate of ER(+) PR(+) was the highest in the group of premenopausal, age between 36-49 and low histological grade patients
Immunohistochemistry
;
Breast Neoplasms
;
Estrogens
;
Progesterone
5.Clinical and CT scan features of fourth ventricle tumors
Journal Ho Chi Minh Medical 2004;8(4):222-227
Study on 73 fourth ventricle tumors that were operated at Cho Ray hospital, from May 2000 to October 2003. The results: tumors were seen in both children and adults, in male more than female at the ages ranging from 2 years old to 64 years old. The most common age group were 1-10 years (52%), then 11-20 years old (21.9%). In fourth ventricle tumors, the median duration of symptoms prior to radiological diagnosis was 6 weeks. The patients experienced symptoms such as headache, vomitting, vertigo. The common syndromes were: raised intracranial pressure syndrome, cerebellar syndrome, pyramidal syndrome and epilepsy. Brain CT scan, absence of cysts and calcifications, homogeneous hyperdensity favor the diagnosis of medulloblastoma. Ependymomas were typically nonhomogeneous hyperdensity, calcified. Astrocytomas showed nonhomogenous hyperdensity and minimal calcification. Most of cases had ventricular dilatation
Cerebral Ventricle Neoplasms
;
diagnosis
;
Tomography Scanners, X-Ray Computed
6.The etiology and treatment of adult intussusception
Journal Ho Chi Minh Medical 2004;8(4):227-231
From January 1999 to December 2003, 60 adult patients with intussusception were treated at Cho Ray Hospital, Hochiminh City. The results showed that: among them, evident etiology was recognized in 86.7% cases, including 63.5% intestinal tumors. Of cases of small intestine tumors, there were 12 benign cases (85.7%), and percentage of colonic tumors were malignant 76.9%. The treatment depends on etiology and site of intussusception. 3 surgical procedures were disinvagination, intestinal resection and right/left hemicolectomy. Surgical successful rate was 93.3%. There was no death
Intussusception
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Adult
;
Therapeutics
;
etiology
7.Study on indications for thoracotomy in treatment to chest trauma
Journal Ho Chi Minh Medical 2004;8(4):231-239
Study on 98 chest trauma patients (78% male, 22% female, aged 9-74) were open-operated at Cho Ray hospital and Gia Dinh People hospital, from June 2001 to June 2003. The results showed that: 44% patients had hypovolemic shock-syndrome accompanying with others injuries. There were 2 indications for thoracotomy: emergency thoracotomy and urgent. The most of chest traumas can be preserve treated. The indications for thoracotomy were in special cases. The valuable signs for thoracotomy: hypovolemic shock syndrome, respiratory decompensation and acute pericadial compression. The anterio-lateral thoracotomy was usually used
Thorax
;
Wounds and Injuries
;
thoracotomy
;
Therapeutics
8.Application of digital subtraction angiography in diagnosis and treatment of severe recurent epistaxis
Journal Ho Chi Minh Medical 2004;8(4):239-344
40 severe recurent epistaxis patients were monitored by digital subtraction angiography at Cho Ray hospital, from October 2001 to October 2003. The results: traumatic carotico-cavernous fistulas 3 cases; related carotid arteries 3 cases: carotid artery ligation; Internal maxillary aneurysms 13 cases: embolization; Related ethmoid artery 2 cases: ethmoid artery ligation. The bleeding sites have not been found clearly on DSA 19 cases: 5 cases in of them have no longer bleeding after DSA and pulled pack out. The DSA is a very important therapeutic application and sometime it was used as definitive treatment
Epistaxis
;
diagnosis
;
Therapeutics
;
Angiography
9.Bilateral urinary stones treated by minimally invasive surgery: 2 cases report
Journal Ho Chi Minh Medical 2004;8(4):245-247
Presention of 2 cases of bilateral urinary lithiasis treated totally by minimally invasive surgey: percutaneous nephrolithotomy, ureteroscopy and retroperitoneal laparoscopic surgery. If well equipped, almost all cases of urolithiasis could be treated by minimally invasive surgery
Urinary Calculi
;
Therapeutics
;
surgery
10.Solitary nodule of the lung: diagnosis and treatment
Journal Ho Chi Minh Medical 2004;8(1):1-6
Solitary nodule is a term, which express a circle or oval shape with maximum diameter < 3cm, in centre or peripheral area of the lung. Solitary nodule was diagnosed by lung tomography, thoracic CT scan and percutaneous biopsy puncture. The treatment: If patients can not be treated by operation: need to monitor and take percutaneous biopsy puncture. If patients can be treated by operation, their disease is reliable benign, need to monitor and take thoracoscopy, take operation with contraindication of endoscopy. If their disease is acute with mediastinal tumors: mediastinal endoscopy but lack of instrument, thoracoscopy should be recommended. Thoracoscopy or open-thoracic surgery denpend on individuals and pathoanatomy’s results
Coin Lesion, Pulmonary
;
diagnosis
;
Therapeutics
;
therapy