No abstract available.
Memory*

This study was conducted to investigate physiological characteristics of Trichoderma spp. isolated from Pleurotus spp. Damage tests of Pleurotus spp. and mycotoxins tests of Trichoderma spp. were also done. The optimal growth temperature of Trichoderma spp. was 27~30degrees C. Although, T. longibrachiatum was able to grow at 37degrees C and grew 30~40 times faster than Pleurotus. The colony colour on PDA medium of T. cf. virens was yellowish green, T. longibrachiatum was yellow, and T. harzianum was turning to bright green. In damage tests of Pleurotus by Trichoderma, T. cf. virens caused the most severe damage to Pleurotus. T. longibrachiatum and T. harzianum caused less damage on Pleurotus but were able to cause greater damage to P. eryngii. One of the mushroom cultivars, P. ostreatus 8 was the most resistant to all Trichoderma spp.. Chitinolytic mycotoxin released by Trichoderma spp. caused 52.7% damage to Pleurotus. Mycotoxins released by T. longibrachiatum caused the greatest damaged (78.6%) on P. eryngii.
Agaricales ; Fungi* ; Mycotoxins ; Ostreidae* ; Pleurotus* ; Trichoderma

PURPOSE: Perinatal asphyxia occurring in newborn is one of the major causes of acute mortality and chronic neurological disability in survivors. We have studied the relationship between early electroencephalography(EEG) findings and clinical course and neurologic outcome in severe asphyxiated neonates. METHODS: Between the period of July 1999 and June 2002, 25 neonates who were diagnosed with severe perinatal asphyxia(1-minute Apgar score of < or =3 and initial pH is less than 7.2) at NICU in Dongsan Medical Center were enrolled. An EEG was recorded and analyzed within three days of life and divided into two groups - group 1(normal or focal change on EEG) and group 2(generalized abnormal EEG). Between the two groups, clinical courses and neurologic outcomes were compared. RESULTS: Fifteen infants(60%) were group 1 and ten infants(40%) were group 2(polyspikes, burst- suppression, generalized low voltage). Associated maternal disease, days of hospitalization, need for ventilator support, delay of oral feeding and convulsion duration are significantly higher and longer in group 2. Also, poor neurologic outcome(expire, developmental delay) was significantly higher in group 2(60%) than group 1(13.3%). CONCLUSION: Thus, the early neonatal EEG in asphyxiated newborn can be a predictable diagnostic tool in assessment of neurologic outcome.
Apgar Score ; Asphyxia ; Electroencephalography ; Hospitalization ; Humans ; Hydrogen-Ion Concentration ; Infant, Newborn* ; Mortality ; Seizures ; Survivors ; Ventilators, Mechanical

Prostatic carcinoma continues to be a major cause of morbidity and mortality in men. Unfortunately, most patients with prostatic carcinoma present to the clinician with established disseminated disease. Earlier detection of prostatic carcinoma is essential of the number of potentially curable patients is to be increased. It is the purpose of this study evaluated a screening program for the early detection of carcinoma of the prostate by transrectal fine needle aspiration cytology. A total of 52 transrectal fine needle aspiration cytology of the prostate compared with histological diagnosis by operation in 41 patients with abnormal prostate by digital rectal examination. Of the 51 prostatic aspirations that could be given a definite cytologic diagnosis, there was histological correlation in 43. The sensitivity was 84.0 percent, specificity 81.5 percent. The false negative rate was 15.4 percent, false positive rate 12.5 percent. There was no apparent complication by transrectal aspiration of the prostate. Our results suggest that transrectal fine needle aspiration of the prostate is an easily performed, diagnostically reliable procedure without complication.
Aspirations (Psychology) ; Biopsy, Fine-Needle* ; Diagnosis ; Digital Rectal Examination ; Humans ; Male ; Mass Screening ; Mortality ; Prostate* ; Sensitivity and Specificity

BACKGROUND: Controversy exists as to whether or not inhalation anesthetics and intravenous anesthetics impair arterial oxygenation (PaO2) during one lung ventilation (OLV). Accordingly, we examined the effect of enflurane and propofol on PaO2 and pulmonary vascular resistance (PVR) during OLV. METHODS: Forty patients, who had prolonged periods of OLV anesthesia with minimal trauma to the nonventilated lung were studied in a cross over design. Patients were randomized to four groups; Group 1 received 1 MAC of enflurane and oxygen from induction until the first 20 min after complete lung collapse, then were switched to propofol 100 g/kg/min (P100). In group 2, the order of the anesthetics was reversed. Group 3, Group 4 received the same order of the anesthetics as Group 1, Group 2, respectively but received propofol 200 g/kg/min (P200). RESULTS: During OLV, the PaO2 values were lower than those with two lung ventilation (TLV), there were no significant differences among each groups and between propofol and enflurane in PaO2, but in the selected patients (n=10, PaO2<120 mmHg during OLV), PaO2 in propofol group was higher than that of enflurane group (p<0.05). Conversion from TLV to OLV caused a significant increase in PVR, but there were no difference in PVR between propofol and enflurane group. CONCLUSIONS: These results suggest that the usual clinical dose of propofol affords no advantage over 1 MAC of enflurane anesthesia except low PaO2 patients during OLV. Propofol might be of value in risk patients of hypoxemia during thoracic surgery when OLV is planned.
Anesthesia ; Anesthetics ; Anesthetics, Inhalation ; Anesthetics, Intravenous ; Anoxia ; Cross-Over Studies ; Enflurane* ; Humans ; Lung ; One-Lung Ventilation* ; Oxygen* ; Propofol* ; Pulmonary Atelectasis ; Thoracic Surgery ; Vascular Resistance ; Ventilation

No abstract available.
Actinomycosis*

No abstract available.
Actinomycosis*

Multilocular cystic renal cell carcinoma appears to be a distinct and rare subtype of renal cell carcinoma with characteristic gross and microscopic features. Multilocular cystic renal cell carcinoma should be separated from multilocular cyst, multilocular cystic nephroma, and renal cell carcinoma with cystic degeneration. We present a case of multilocular cystic renal cell carcinoma. A 61-year-old man presented with right flank pain for 4 years. The computerized tomography revealed multilocular cystic mass in the upper pole of right kidney. The cystic mass measured 4.5x4 cm. The cyst was multilocular and locules not communicated with each other. The solid area was not present. Microscopically, the locules were lined by flat or cuboidal neoplastic clear cells. The clear cells were focally aggregated in the septa. The nephron was not present in the septa.
Male ; Humans ; Cysts

PURPOSE: Although the conventional clinical, histopathological, and moleculobiological factors of bladder tumor provide a certain degree of stratification of tumor biological potential, it is difficult to make an accurate and reliable prediction of tumor recurrence with known prognostic factors due to tumor heterogeneity. So we attempted to devise a scoring system reflecting various prognostic factors to predict tumor recurrence more accurately in superficial bladder carcinoma. MATERIALS AND METHODS: We reviewed retrospectively the clinical records and pathological specimens of 46 patients with superficial bladder cancer, who underwent transurethral resection of bladder tumor and intravesical Bacillus Calmette-Guerin (BCG) instillation between September, 1991 and December, 1996. The mean follow-up was 29 months. We examined the prognostic parameters such as tumor stage, grade, tumor with or without CIS, size, number, p53 expression and investigated the relation between the prognostic factors and the tumor recurrence. We assigned 1 and 2 for Ta and T1; 1 and 2 for tumor size(<3cm and > or =3cm); 1 and 2 for tumor number( < or =2 and > or =3); 1, 2 and 3 for grades( I, II and III); 2 if CIS is found and 1 if not; 2 if p53 is expressed more than 20%(strong positive) and 1 if p53 is not expressed or less than 20%(weakly positive). We summed the points assigned to all categories for each patient, and investigated tumor recurrence according to total points by the scoring system. We corrected the scoring system by deleting the insignificant prognostic factors in this study which was named the corrected scoring system. We recounted the points based on it. RESULTS: Tumor recurred in 15 out of 46 patients(32.6%). Recurrence rate in patients with p53(strong positive) and with p53(weakly positive) was 47.3 and 18.5%, respectively (p<0.05). The recurrence rate of stage Ta and T1 was 40.0 and 30.6%(p>0.05) and that of grades I, II and III was 0, 20.8 and 55.6%(p<0.05), respectively. The recurrence rate of patients with and without CIS was 52.9 and 26.9%(p<0.05), respectively. The recurrence rate for patients with size of tumors > or =3cm and<3cm was 50 and 26.5%, respectively (p>0.05). Patients with number of tumors < or =2(22.6%) have a lower recurrence rate than those with tumors> or =3(53.3%)(p<0.05). p53 expression, high grade, tumor with CIS and number(> or =3) were considered as prognostic factors that affected the recurrence. For patients with summed points 4 to 9 based on the corrected scoring system, the recurrence rate was zero%(0/16) in patients with lower score(4 or 5), 31.8%(8/21) in those with intermediate score(6 or 7), and 77.8%(7/9) in those with higher score(8 or 9)(lower and intermediate score vs higher score: p<0.005). CONCLUSIONS: The results suggested that this scoring system reflecting various prognostic factors can be a reliable method predicting the tumor recurrence. This scoring system awaits its application to more cases of bladder tumor and its refinement, if necessary.
Bacillus ; Follow-Up Studies ; Humans ; Population Characteristics ; Recurrence* ; Retrospective Studies ; Urinary Bladder Neoplasms ; Urinary Bladder*

We report a case of renal oncocytoma in 46-year old woman and review the literature. She had been asymptomatic except a visible protruding mass on the left abdomen and she underwent successful transperitoneal nephrectomy. The kidney weighed 4,800 gm, presented a well capsulated round mass and homogenous tan-brown colored cut surface. Renal oncocytoma, a rare neoplasm thought to arise from proximal tubular epithelial cells, exhibits a benign clinical course. They tend to misdiagnosed as renal cell carcinoma preoperatively. Histopathological studies confirm the oncocytic feature of the tumor cells, it shows finely granular eosinophilic cytoplasm(oncocyte) light microscopically, and the cytoplasm is filled with innumerable mitochondria with a paucity of other organelles ultrastructurally.
Abdomen ; Adenoma, Oxyphilic* ; Carcinoma, Renal Cell ; Cytoplasm ; Eosinophils ; Epithelial Cells ; Female ; Humans ; Kidney ; Middle Aged ; Mitochondria ; Nephrectomy ; Organelles