1.Comparison of transarterial n-BCA and Onyx embolization of brain arteriovenous malformations: A single-center 18-year retrospective analysis
Faraz BEHZADI ; Daniel M HEIFERMAN ; Amy WOZNIAK ; Benjamin AFRICK ; Matthew BALLARD ; Joshua CHAZARO ; Brandon ZSIGRAY ; Matthew REYNOLDS ; Douglas E ANDERSON ; Joseph C SERRONE
Journal of Cerebrovascular and Endovascular Neurosurgery 2022;24(2):144-153
Objective:
Brain arteriovenous malformations (AVM) are commonly treated with endovascular embolization. Due to the rapid evolution of endovascular technology and lack of consistent practice guidelines regarding AVM embolization, further study of AVM embolization outcomes is warranted.
Methods:
We conducted a retrospective review of AVMs embolized at a single center from 2002-2019. Patient demographics, AVM characteristics, intention of embolization, and angiographic and clinical outcome after embolization were recorded. We compared the embolization results of those treated with n-butyl cyanoacrylate (n-BCA) and Onyx.
Results:
Over an 18-year period at our institution, 30 (33%) of 92 AVMs were treated with embolization. n-BCA was used in 12 cases and Onyx in 18 cases. Eighty-seven pedicles were embolized over 47 embolization sessions. Fifty percent of AVMs treated with n-BCA underwent more than one embolization session compared to 22% when Onyx was used. The median total percent volume reduction in the n-BCA AVMs was 52% compared to 51% in Onyx AVMs. There were 2 periprocedural complications in the n-BCA cohort and none in the Onyx cohort.
Conclusions
In this small retrospective series, Onyx and n-BCA achieved similar occlusion results, although n-BCA required more sessions and pedicles embolized to do so.
2.Variability of extracorporeal cardiopulmonary resuscitation utilization for refractory adult out-of-hospital cardiac arrest: an international survey study.
Patrick J COPPLER ; Benjamin S ABELLA ; Clifton W CALLAWAY ; Minjung Kathy CHAE ; Seung Pill CHOI ; Jonathan ELMER ; Won Young KIM ; Young Min KIM ; Michael KURZ ; Joo Suk OH ; Joshua C REYNOLDS ; Jon C RITTENBERGER ; Kelly N SAWYER ; Chun Song YOUN ; Byung Kook LEE ; David F GAIESKI
Clinical and Experimental Emergency Medicine 2018;5(2):100-106
OBJECTIVE: A growing interest in extracorporeal cardiopulmonary resuscitation (ECPR) as a rescue strategy for refractory adult out-of-hospital cardiac arrest (OHCA) currently exists. This study aims to determine current standards of care and practice variation for ECPR patients in the USA and Korea. METHODS: In December 2015, we surveyed centers from the Korean Hypothermia Network (KORHN) Investigators and the US National Post-Arrest Research Consortium (NPARC) on current targeted temperature management and ECPR practices. This project analyzes the subsection of questions addressing ECPR practices. We summarized survey results using descriptive statistics. RESULTS: Overall, 9 KORHN and 4 NPARC centers reported having ECPR programs and had complete survey data available. Two KORHN centers utilized extracorporeal membrane oxygenation only for postarrest circulatory support in patients with refractory shock and were excluded from further analysis. Centers with available ECPR generally saw a high volume of OHCA patients (10/11 centers care for >75 OHCA a year). Location of, and providers trained for cannulation varied across centers. All centers in both countries (KORHN 7/7, NPARC 4/4) treated comatose ECPR patients with targeted temperature management. All NPARC centers and four of seven KORHN centers reported having a standardized hospital protocol for ECPR. Upper age cutoff for eligibility ranged from 60 to 75 years. No absolute contraindications were unanimous among centers. CONCLUSION: A wide variability in practice patterns exist between centers performing ECPR for refractory OHCA in the US and Korea. Standardized protocols and shared research databases might inform best practices, improve outcomes, and provide a foundation for prospective studies.
Adult*
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Cardiopulmonary Resuscitation*
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Catheterization
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Coma
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Extracorporeal Membrane Oxygenation
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Heart Arrest
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Humans
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Hypothermia
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Korea
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Out-of-Hospital Cardiac Arrest*
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Practice Guidelines as Topic
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Prospective Studies
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Research Personnel
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Shock
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Standard of Care