1.Outcomes of oral tongue cancer: does age matter?
Connie S P YIP ; Tze Choong CHARN ; Joseph T S WEE ; Terence W K TAN ; Christopher GOH ; Hiang Khoon TAN ; Kam Weng FONG
Annals of the Academy of Medicine, Singapore 2010;39(12):897-897
INTRODUCTIONThis is a retrospective study aimed to analyse the outcomes of oral tongue cancer with emphasis on young people.
MATERIALS AND METHODSPatients treated radically between 1998 and 2006 were included and categorised according to treatment modalities (Group A: Surgery, Group B: Surgery and adjuvant therapy, Group C: Definitive radiotherapy) and age groups (≤ 40 and > 40 years). Overall survival (OS), disease-free survival (DFS), locoregional relapse-free survival (LRS) and metastasis-free survival (MFS) were estimated using Kaplan-Meier method.
RESULTSThere were 123 patients with 32%, 53% and 15% in Group A, B and C, respectively. Of these, 17 patients (14%) were ≤40 years with 6 (15%), 8 (12%) and 3 (16%) young oral tongues in Group A, B and C, respectively. Five-year OS and DFS were 69%/72%, 41%/47% and 16%/9.5% for Group A, B and C, respectively. Young patients had similar survival as the older population with 5-year OS of 83%, 75% and 33% in Group A, B and C, as compared to the older patients (66%, 36% and 13%, respectively).
CONCLUSIONYoung oral tongue patients did not have worse outcomes.
Adult ; Age Factors ; Aged ; Aged, 80 and over ; Carcinoma, Squamous Cell ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Tongue Neoplasms ; therapy ; Treatment Outcome ; Young Adult