1.A Study of Blood Pressure Measurement in Newborn Infants.
Yoon Deok KIM ; Joong Whan CHOI ; Chong Ku YUN
Journal of the Korean Pediatric Society 1986;29(8):7-17
No abstract available.
Blood Pressure*
;
Humans
;
Infant, Newborn*
2.A Case of Successful Ablation of Right-Sided Accessory Pathway during Atrial Fibrillation.
Kee Joon CHOI ; Jae Joong KIM ; Cheol Whan LEE ; You Ho KIM
Korean Circulation Journal 1996;26(4):906-912
The occurrence of atrial fibillation during an electrophysiologic study or catheter ablation in patients with accessory pathways is a common problem and sometimes complicates the localization and ablation procedure of accessory pathways. In patients with sustained atrial fibrillation, it is often time-consuming to terminate atrial fibrillation by drugs or electrical cardioversion. We performed successful radiofrequency catheter ablation in a patient with right-sided accessory pathway during atrial fibrillation requiring repeated electrical cardioversion. The target site was determined by activation mapping and morphology of unipolar electrogram at a site of early ventricular activation.
Atrial Fibrillation*
;
Catheter Ablation
;
Electric Countershock
;
Humans
3.Implantable Cardioverter-Defibrillator(ICD) Therapy in a Patient with the Long QT Syndrome.
Kee Joon CHOI ; Cheol Whan LEE ; Jae Joong KIM ; You Ho KIM
Korean Circulation Journal 1996;26(6):1198-1203
The long QT syndrome is believed to result from abnormalities of cardiac sympathetic innervation and of myocardial repolarization. The therapeutic modalities for patients with ventricular arrhythmias due to the long QT syndrome include beta blocker, cardiac sympathetic denervation, pacemaker and ICD implantation. Recently, we underwent transvenous ICD implantation in a patient with this syndrome who had recurrent syncopal episodes due to rapid polymorphic ventricular tachycardia and strong family history of sudden death.
Arrhythmias, Cardiac
;
Death, Sudden
;
Humans
;
Long QT Syndrome*
;
Sympathectomy
;
Syncope
;
Tachycardia, Ventricular
4.Implantable Cardioverter-Defibrillator(ICD) Therapy in a Patient with the Long QT Syndrome.
Kee Joon CHOI ; Cheol Whan LEE ; Jae Joong KIM ; You Ho KIM
Korean Circulation Journal 1996;26(6):1198-1203
The long QT syndrome is believed to result from abnormalities of cardiac sympathetic innervation and of myocardial repolarization. The therapeutic modalities for patients with ventricular arrhythmias due to the long QT syndrome include beta blocker, cardiac sympathetic denervation, pacemaker and ICD implantation. Recently, we underwent transvenous ICD implantation in a patient with this syndrome who had recurrent syncopal episodes due to rapid polymorphic ventricular tachycardia and strong family history of sudden death.
Arrhythmias, Cardiac
;
Death, Sudden
;
Humans
;
Long QT Syndrome*
;
Sympathectomy
;
Syncope
;
Tachycardia, Ventricular
5.Two Cases of Folliculosebaseous Cystic Hamatroma.
Nam Ho LEE ; In Uck LEE ; In Whan NAM ; Eung Ho CHOI ; Won Soo LEE ; Joong Gie KIM ; Sung Ku AHN
Korean Journal of Dermatology 1999;37(1):101-104
Folliculosebaceous cystic hamartoma is a rare, benign condition. The histological criteria of folliculosebaceous cystic hamartoma have been well established by Kimura et al. We report two cases of folliculosebaceous cystic hamartoma which showed typical histological findings. As far as we know, it has not yet been reported in Korean dermatological literature. The first case is a 23-year-old man who had a pedunculated nodule on the scalp. The second one is a 46-year-old man who had a bean sized pedunculated nodule on the left cheek.
Cheek
;
Hamartoma
;
Humans
;
Middle Aged
;
Scalp
;
Young Adult
6.The Significance of Micrometastasis in Axillary Lymph Node Negative Breast Cancer.
Jang Yong KIM ; Joo Whan JEONG ; Sei Joong KIM ; Sun Keun CHOI ; Ze Hong WOO ; Seok Hwan SHIN
Journal of Korean Breast Cancer Society 2000;3(1):16-24
PURPOSE: Lymph node metastasis is one of the most important prognostic factors in breast cancer. Survival of patients with axillary node positive breast cancer is worse than that of patients with axillary lymph node negative breast cancer. Recently, some authors suggest that axillary dissection may be avoidable if sentinel nodes of the breast cancer do not harbour metastasis. However, 15-20 % of patients with lymph node negative breast cancer recurs within 10 years. Micrometastasis, which was missed or not detected in routine histologic examination, is thought to be one of the reasons for recurrence of axillary node negative breast cancer patients. METHODS: We investigated the frequency of micrometastasis and any clinical significance of micrometastasis in the breast cancer by immunohistochemical staining with anti-cytokeratin antibody from July, 1996 to November, 1990. 70 patients who underwent curative resection for axillary node negative breast cancer were studied retrospectively. We used paraffin blocks of lymph nodes which did not show metastasis by conventional pathological examination. After preparation of tissue blocks with a serial sectioning technique, specimens were stained by an immunohistochemical method using anti-cytokeratin antibody. Hematoxylin-eosin stainings were also repeated. We define metastasis less than 2mm as a micrometastasis. RESULTS: The results showed that micrometastasis were found in 8 of 70 cases(11.4%). There was a significant relationship between the micrometastasis and tumor size. With median follow-up of 20 months, we found 3 recurrences in 70 patients. : 2 recurrences(3.2%) in the 62 axillary node negative breast cancer patients and 1 recurrences(12.5%) in 8 micrometastasis patients. CONCLUSIONSThe results showed that micrometastasis of lymph node in breast cancer might increase the rick for development of breast cancer recurrence. But, there was no significant relationship between the micrometastasis and recurrence of breast cancer because of small numbers of recurrences and relatively short follow-up period. Long tern follow-up will be needed for further evaluation.
Animals
;
Breast Neoplasms*
;
Breast*
;
Charadriiformes
;
Follow-Up Studies
;
Humans
;
Lymph Nodes*
;
Neoplasm Metastasis
;
Neoplasm Micrometastasis*
;
Paraffin
;
Recurrence
;
Retrospective Studies
7.Ten years of experience in the prevention of mother-to-child human immunodeficiency virus transmission in a university teaching hospital.
Jung Weon PARK ; Tae Whan YANG ; Yun Kyung KIM ; Byung Min CHOI ; Hai Joong KIM ; Dae Won PARK
Korean Journal of Pediatrics 2014;57(3):117-124
PURPOSE: Administration of antiretroviral drugs to mothers and infants significantly decreases mother-to-child human immunodeficiency virus (HIV) transmission; cesarean sections and discouraging breastfeeding further decreases this risk. The present study confirmed the HIV status of babies born to mothers infected with HIV and describes the characteristics of babies and mothers who received preventive treatment. METHODS: This study retrospectively analyzed medical records of nine infants and their mothers positive for HIV who gave birth at Korea University Ansan Hospital, between June 1, 2003, and May 31, 2013. Maternal parameters, including HIV diagnosis date, CD4+ count, and HIV ribonucleic acid (RNA) copy number, were analyzed. Infant growth and development, HIV RNA copy number, and HIV antigen/antibody test results were analyzed. RESULTS: Eight HIV-positive mothers delivered nine babies; all the infants received antiretroviral therapy. Three (37.5%) and five mothers (62.5%) were administered single- and multidrug therapy, respectively. Intravenous zidovudine was administered to four infants (50%) at birth. Breastfeeding was discouraged for all the infants. All the infants were negative for HIV, although two were lost to follow-up. Third trimester maternal viral copy numbers were less than 1,000 copies/mL with a median CD4+ count of 325/microL (92-729/microL). Among the nine infants, two were preterm (22.2%) and three had low birth weights (33.3%). CONCLUSION: This study concludes that prophylactic antiretroviral therapy, scheduled cesarean section, and prohibition of breastfeeding considerably decrease mother-to-child HIV transmission. Because the number of infants infected via mother-to-child transmission may be increasing, studies in additional regions using more variables are necessary.
Breast Feeding
;
CD4 Lymphocyte Count
;
Cesarean Section
;
Diagnosis
;
Female
;
Growth and Development
;
Gyeonggi-do
;
HIV Infections
;
HIV*
;
Hospitals, Teaching*
;
Humans
;
Infant
;
Infant, Low Birth Weight
;
Infant, Newborn
;
Infectious Disease Transmission, Vertical
;
Korea
;
Lost to Follow-Up
;
Medical Records
;
Mothers
;
Parturition
;
Postnatal Care
;
Pregnancy
;
Pregnancy Trimester, Third
;
Retrospective Studies
;
RNA
;
Zidovudine
8.Long-term Clinical Outcome and Echocardiographic Restenosis after Successful Percutaneous Transmitral Commissurotomy.
Young Hak KIM ; Duk Hyun KANG ; Jae Kwan SONG ; Kee Joon CHOI ; Cheol Whan LEE ; Myeong Ki HONG ; Jae Joong KIM ; Seong Wook PARK ; Seung Jung PARK
Korean Circulation Journal 1998;28(2):194-204
BACKGROUND: The purpose of this study was to assess the clinical outcome and echocardiographic incidence of restenosis after successful percutaneous transmitral commissurotomy (PTMC) and to identify predictors of restenosis. METHODS: Between 1989 and 1992, Inoue PTM (n=73) and double balloon technique (n=85) were used in 158 consecutive patients (male 52, age; 41+/-11 year) with mitral stenosis. Clinical and echocardiographic examinations were performed annually in 137 patients who exhibited good initial result with PTMC (mitral valve area 1.5cm (2) and mitral regurgitation[MR] 2+). Restenosis was defined as a mitral valve area< (MVA) 1.5cm (2) or more than 50% loss of the initial gain in MVA. Commissural mitral regurgitation (CMR) was defined as MR originating from medical or lateral commissure on color flow imaging and regarded as an index of complete commissural splitting. RESULTS: Immediately after PTMC, MVA increased from 0.9+/-0.2cm (2) to 1.8+/-0.3cm (2) and functional class improved up to NYHA class 1 or 2 in all patients. Annual echocardiographic follow-ups were completed in 129 (94%) patients and mean follow-up duration was 54+/-21 months. Adverse events occurred in 16 (13%) patients (1 death, 3 mitral valve replacement, 3 re-PTMCs, 9 deterioration of the NYHA class), and restenosis occurred in 41 (32%) patients. Event-free and restenosis-free survival rates at 7 years were 776 % and 586 %, respectively. According to multivariate Cox analysis, restenosis (p=0.0017, relative risk[r.r]=2.82) was the only predictor of adverse events ; smaller increase ( 1.0cm (2)) of MVA (p=0.0001, r.r=4.8) and the absence of CMR (p=0.0000, r.r=4.8) were independent predictors of restenosis. CONCLUSION: Long-term clinical outcomes and restenosis rates after PTMC are favorable and immediate results after PTMC can predict late restenosis better than baseline clinical and echocardiographic characteristics.
Echocardiography*
;
Follow-Up Studies
;
Humans
;
Incidence
;
Mitral Valve
;
Mitral Valve Insufficiency
;
Mitral Valve Stenosis
;
Survival Rate
9.Treatment of Diffuse In-stent Restenosis with Rotational Atherectomy Followed by Radiation Therapy with a 188Re-MAG3-Filled Balloon.
Seong Wook PARK ; June Hong KIM ; Siwan CHOI ; Myeong Ki HONG ; Dae Hyuk MOON ; Seung Jun OH ; Cheol Whan LEE ; Jae Joong KIM ; Seung Jung PARK
Korean Circulation Journal 2001;31(5):466-475
BACKGROUND: Rotational atherectomy has been shown to be safe and efficient for the treatment of ISR, but the recurrence rate is still high. Intracoronary-irradiation after rotational atherectomy may be a reasonable approach to prevent recurrent ISR. SUBJECTS & METHODS: Fifty consecutive patients with diffuse ISR (length > 10 mm) in native coronary arteries underwent rotational atherectomy and adjunctive balloon angioplasty followed by beta irradiation using a 188Re-MAG3-filled balloon catheter. The radiation dose was 15 Gy at 1.0 mm deep into vessel wall. RESULTS: Mean length of the lesion and irradiated segment was 25.6 +/- 12.7 mm and 37.6 +/- 11.2 mm, respectively. The radiation was delivered successfully to all patients, with a mean irradiation time of 201.8 61.7 seconds. No adverse event including myocardial infarction, death, or stent thrombosis occurred during the follow-up period (mean 10.3 +/- 3.7 months) and non-target vessel revascularization was needed in one patient. Six-month binary angiographic restenosis rate was 10.4 % and loss index was 0.17 +/- 0.31. CONCLUSIONS: beta irradiation using 188Re-MAG3-filled balloon following rotational atherectomy is safe and feasible for patients with diffuse ISR, and it may improve the clinical and angiographic outcomes. Further prospective randomized trials are warranted to evaluate the synergistic effect of debulking and irradiation in patients with diffuse ISR.
Angioplasty, Balloon
;
Atherectomy, Coronary*
;
Catheters
;
Coronary Vessels
;
Follow-Up Studies
;
Humans
;
Myocardial Infarction
;
Recurrence
;
Stents
;
Thrombosis
10.Analysis of Lymph Nodes Number according to Various Modifications of Neck Dissection.
Joong Wha KOH ; Hae Dong YANG ; Jung Whan SONG ; Ho Seok CHOI
Korean Journal of Otolaryngology - Head and Neck Surgery 2000;43(8):862-865
BACKGROUND AND OBJECTIVES: The type of neck dissection performed for head and neck cancers depends on the experience of the surgeon and the status of the neck metastasis. The purpose of this study was to quantify the extent of lymphadenectomy achieved according to the various modifications of neck dissection based on microscopic pathologic analysis and to analyze the difference in the number of lymph nodes between the types of neck dissection. MATERIALS AND METHODS: Charts and pathologic finding of patients who underwent neck dissection from June 1994 to October 1999 were reviewed. Patients who received selective neck dissection or preoperative radiotherapy to the neck were excluded. The samples were 65 necks and were divided into four groups based on Medina's classification: radical neck dissection (group 1), Type I modified radical neck dissection (group 2), Type II modified radical neck dissection (group 3), and Type III modified neck dissection (group 4). The number of lymph nodes was counted by a pathologic microscopic examination for each region of specimens. The intergroup difference was analyzed by a one-way between-group analysis of variance (ANOVA). RESULTS: The mean number of dissected lymph nodes per specimen was 43.6 in group 1, 38.8 in both groups of 2 and 3, and 30.3 in group 4. Group 4 was significantly different from group 1 (p<0.05). Especially, the number of dissected lymph nodes from level II, III, IV of group 4 was significantly different from those of group 1 (p<0.05). There was no significant difference between other groups. CONCLUSIONS: The number of dissected lymph nodes decreases as the number of preserved non-lymphatic tissue structures increases. Level II, III, IV are less completely operated regions in functional neck dissection.
Classification
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Head
;
Humans
;
Lymph Node Excision
;
Lymph Nodes*
;
Neck Dissection*
;
Neck*
;
Neoplasm Metastasis
;
Radiotherapy