1.Recent Advance in Antiepileptic.
Joong Koo KANG ; Myoung Jong LEE
Journal of the Korean Medical Association 1998;41(6):672-681
No abstract available.
2.Symptomatic Hyponatremia Induced by Oxcarbazepine: 2 Cases .
Sang Ahm LEE ; Soon Keum LEE ; Joong Koo KANG
Journal of Korean Epilepsy Society 2001;5(1):79-81
Although oxcarbazepine (OXC)-induced hyponatremia is usually asymptomatic, it can lead to serious complications. We reports two cases of symptomatic hyponatremia induced by OXC. First case was 39-year-old female with partial epilepsy who developed the exceeding tiredness, headache, and seizures under OXC with a serum sodium level of 121 mEq/L. After the discontinuation of OXC, serum sodium was normalized and the clinical symptoms disappeared. Second case was 48-year-old female with partial epilepsy who complained of the fluctuating tiredness and fatigability, and then eventually developed seizures after OXC was increased in dosage. At that time, serum sodium was 121 mEq/L. She remained asymptomatic with normal level of serum sodium even if OXC was maintained with topiramate. Our cases may suggest that symptomatic hyponatremia is not rare unlike the results from previous studies. Therefore, clinician should be alert to mild symptoms such as headache, lethargy, and tiredness in patients treated with OXC.
Adult
;
Epilepsies, Partial
;
Female
;
Headache
;
Humans
;
Hyponatremia*
;
Lethargy
;
Middle Aged
;
Seizures
;
Sodium
3.MR Imaging of the Pigmented Villonodular Synovitis of the Knee.
Sang Hoon LEE ; Joong Mo AHN ; Heung Sik KANG ; Chu Wan KIM ; Han Koo LEE
Journal of the Korean Radiological Society 1994;31(1):165-170
PURPOSE: To describe the magnetic resonance (MR) findings of pigmented villonodular synovitis(PVNS) of the knee, and to evaluate the clinical value of MR in the diagnosis of PVNS. MATERIALS AND METHODS:MR imagings of seven patients with PVNS were studied. The type of lesion, presence of bony erosion, the signal intensity, and the relationship between contrast enhancement and signal intensity on T2-weighted images were analyzed, retrospectively. RESULTS: The lesion was mainly villous in three patients and nodular in four, and bony erosion was seen in one patient. On T2-weighted image, the signal intensity of the villous form was mixed iso- and hypointense in two, hypointense in one, and that of the nodular form was heterogeneous with hypo-, iso-, and hyperintensities. The hypointense portion on T2-weighted image showed poor contrast enhancement, which may suggest hemosiderin deposition or advanced fibrosis. The iso- or hyperintense portion on T2-weighted image showed strong enhancement, which suggest active cellular proliferation. CONCLUSION:MR imaging could be a very useful modality in the diagnosis as well as prediction of histological findings of the PVNS.
Cell Proliferation
;
Diagnosis
;
Fibrosis
;
Hemosiderin
;
Humans
;
Knee*
;
Magnetic Resonance Imaging*
;
Retrospective Studies
;
Synovitis, Pigmented Villonodular*
4.Pathologic Analysis of 39 Cases of Epilepsy Surgery.
Young Mee CHO ; Joong Koo KANG ; Youn Mee HWANG ; Jung Kyo LEE ; Ghee Young CHOE
Korean Journal of Pathology 1996;30(5):388-395
Pharmacologic therapy is still the primary management for epilpsy; however, surgical treatment is a reasonable therapeutic option for patients suffering from medically intractable seizures, especially temporal lobe epilepsy having a documented unilateral epileptogenic area. Thirty nine patients with pharmaco-resistant complex partial seizures underwent anterior temporal lobectomy and hippocampectomy in 38 cases and frontal cortisectomy in one case. On pathological examination, hippocampal sclerosis was a predominent pathologic finding and was identified in 18 cases. Other non-neoplastic lesions consisted of 5 cases of vascular lesions(2 cavernous angiomas, 2 arteriovenous malformations and 1 angiomatosis), 3 cases of fibrous nodule, 2 cases of cicatrical changes of cerebral cortex, and 1 case of parasitic infection. Neoplasms including two cases of oligodendroglioma and one case of anaplastic astrocytoma were also noted. In seven cases, there was no detectable lesion on gross and microscopic examination. On post-operative follow-up, seizures were completely terminated in most cases(31 cases, 79%). The rest of the patients also displayed marked alleviation of symptoms. The seizures tended to recur more aften among the patients with neoplasm or no pathologically detectable lesion. In order to detect any minute pathological lesion, thorough gross and microcsopic examinations are considered to be essential.
5.Correlation between Preexcision ECoG Patterns and MRI Findings and Clinical Significance of Postexcision ECoG after Temporal Lobectomy.
Joong Koo KANG ; Youn Mee HWANG
Journal of the Korean Neurological Association 1996;14(2):425-432
Role of intraoperative ECoG is uncertain and still controversial. We investigated the correlation of preexcision ECoG (pre-ECoG) patterns with MRI findings and the correlation of the presence or absence of residual spikes in postexcision ECoG (post-ECoG) with surgical outcome. We retrospectively studied 29 temporal lobectomized patients (follow-up period: > 16 mons). The ECoG was performed using two subdural strips on the mesiobasal and lateral temporal lobe. Topography and frequency of epileptiform discharges (ED) in pre-ECoG were analyzed and correlated with hippocampal atrophy only or hippocampal and lateral temporal atrophy in MRI. Among the 15 patients with hippocampal atrophy only, pre-ECoG showed mesial temporal dominant ED in 8 ( 53.3 %), diffuse ED in 3 ( 20.0 %) and lateral temporal dominant ED in 4 ( 26.7 %). In 14 patients with hippocampal and lateral temporal atrophy, mesial temporal dominant ED showed in 2 ( 14.3%), diffuse ED in 8 ( 57.1 %), and lateral temporal dominant ED in 4 ( 28.6%). Compared to patients with hippocampal atrophy only, there was statistically significant widespread epilepiiform discharges on the mesial and lateral temporal area in patients with hippocampal and lateral temporal atrophy( p<0.05 ). All of 6 patients without residual spikes and 19 out of 23 patients with residual spikes in post-ECoG were seizure free or aura only after surgery. But presence or absence of residual spikes post-ECoG is not statistically correlated with surgical outcome (p>0.3).
Atrophy
;
Epilepsy
;
Humans
;
Magnetic Resonance Imaging*
;
Retrospective Studies
;
Seizures
;
Temporal Lobe
6.Determining Brain Death.
Journal of the Korean Medical Association 2006;49(6):493-501
Brain death is a clinical diagnosis. The three cardinal findings in brain death are coma or unresponsiveness, absence of brainstem reflexes, and apnea. The clinical examination of the brainstem includes testing of brainstem reflexes, determination of the patient's ability to breath spontaneously, and evaluation of the motor response to pain. Spontaneous and reflex movements originating from the spinal cord neurons may occur in brain-dead patients. An awareness of spinal reflexes may prevent delays in and misinterpretations of the brain-death diagnosis. In some countries including Korea, our country, confirmatory tests are required by law when determining brain death. However, a confirmatory test is not usually mandatory except for patients in whom specific components of clinical testing cannot be evaluated reliably.
Apnea
;
Brain Death*
;
Brain Stem
;
Brain*
;
Coma
;
Diagnosis
;
Humans
;
Jurisprudence
;
Korea
;
Neurons
;
Reflex
;
Spinal Cord
7.Clinical experience and follow-up study with prognostic factors for colorectal carcinoma.
Joong Ki MIN ; Koo Jeong KANG ; Yong Ki PARK ; Chang Rock CHOI ; Chung Hee GHI
Journal of the Korean Society of Coloproctology 1993;9(2):151-161
No abstract available.
Colorectal Neoplasms*
;
Follow-Up Studies*
8.Clinical experience and follow-up study with prognostic factors for colorectal carcinoma.
Joong Ki MIN ; Koo Jeong KANG ; Yong Ki PARK ; Chang Rock CHOI ; Chung Hee GHI
Journal of the Korean Society of Coloproctology 1993;9(2):151-161
No abstract available.
Colorectal Neoplasms*
;
Follow-Up Studies*
9.Tendon reconstruction of the hand in Patients with Old Flexor Tendon Injuries
Han Koo LEE ; Moon Sang CHUNG ; In Ho CHOI ; Soo Yong LEE ; Hee Joong KANG
The Journal of the Korean Orthopaedic Association 1984;19(2):277-288
No abstract available in English.
Hand
;
Humans
;
Tendon Injuries
;
Tendons
10.Comparative analysis of rubber band ligation and hemorrhoidectomy for prolapsing hemorrhoids.
Koo Jeong KANG ; Kwang Min PARK ; Tae Ki LIM ; Sung Dae PARK ; Ok Suk BAE ; Joong Shin KANG
Journal of the Korean Surgical Society 1991;40(6):782-789
No abstract available.
Hemorrhoidectomy*
;
Hemorrhoids*
;
Ligation*
;
Rubber*