PURPOSE: An acute scrotum is a pathologic condition of the scrotum or intrascrotal contents that require emergency medical or surgical treatment. Because proper treatment and the outcomes are very important in reproduction, the records of patients who had acute scrotal diseases were reviewed for early and proper diagnosis and treatment. MATERIALS AND METHODS: The medical records of 313 patients with acute scrotal pain and swelling were retrospectively reviewed. The final diagnoses were made from the symptoms, a physical examination, the laboratory tests, a color Doppler ultrasound (US), and the surgical findings in cases that underwent surgery. Age, the presence of a urinary tract infection, an underlying disease, seasonal distributions, laterality and the accuracy of color Doppler US in acute epididymitis and testicular torsion were all analyzed. The missed cases of testicular torsion were also reviewed carefully. RESULTS: The most common disease of an acute scrotum was acute epididymitis in both adults and children. Urinary tract infections were not common in children with acute epididymitis. Testicular torsion occurred commonly in the left side, while acute epididymitis developed in same distributions. The mean age of an acute scrotum were 24.1 years; a testicular torsion was 16.0 years and an acute epididymitis was 25.4 years. The color Doppler US demonstrated a 82.5% sensitivity, a 100% specificity, a 100% positive predictive value and a 97.5% negative predictive value for testicular torsion. CONCLUSIONS: Acute epididymitis is also common in children. Although color Doppler US is useful in a differential diagnosis of an acute scrotum, a careful physical examination and follow up of the patient status are important to reduce the incidence of a misdiagnosis.
Adult ; Child ; Diagnosis ; Diagnosis, Differential* ; Diagnostic Errors ; Emergencies ; Epididymitis* ; Humans ; Incidence ; Male ; Medical Records ; Physical Examination ; Reproduction ; Retrospective Studies ; Scrotum* ; Seasons ; Sensitivity and Specificity ; Spermatic Cord Torsion* ; Ultrasonography ; Ultrasonography, Doppler, Color ; Urinary Tract Infections

Splenic abscess is an uncommon but frequently fatal condition. Signs and symptoms are variable and do not always include left upper quadrant pain or tenderness. Unexplained thrombocytosis in a septic patient with persistent left pleural effusion is suggestive of splenic abscess. We report a case of splenic abscess with complicated multiple fistulas by Klebsiella pneumoniae which was successfully managed by antibiotic therapy, and percutaneous catheter drainage.
Abscess* ; Catheters ; Drainage ; Fistula* ; Humans ; Klebsiella pneumoniae* ; Klebsiella* ; Pleural Effusion ; Thrombocytosis

Paraduodenal hernias are a rare congenital malformation, but they are the most common internal hernias. They develop secondary to a failure in midgut rotation, which may lead to small bowel obstruction or other clinical manifestations. The authors recently experienced a case of a left paraduodenal hernia presenting with unusual symptoms of left flank pain and vomiting.
Adult ; Hernia/*complications/*diagnosis/pathology/surgery ; Humans ; Intestinal Obstruction/*etiology/surgery ; Male

OBJECTIVE: This study is designed to investigate the association of tumorigenesis with DNA repair gene, N-methylpurine-DNA-glycosylase(MPG) in astrocytic tumors. METHODS: MPG mRNA expression and localization in the 30 astrocytic tumors and 7 tumor-adjacent brain tissues was examined by reverse transcriptase-polymerase chain reaction(RT-PCR) and RNA in situ hybridization. Expression and intracellular localization of MPG protein was determined by immunohistochemistry. Statistical analysis was performed by ANOVA with a p value<0.05 considered statistically significant. RESULTS: MPG mRNA expression in RT-PCR was significantly higher in grade IV tumor tissues than in brain tissues adjacent to tumor or in grade II-III astrocytic tumor tissues(p<0.05). MPG mRNA in in situ hybridization was detected both in brain tissues adjacent to tumor and in astrocytic tumor tissues, regardless of the tumor grades. However, MPG protein localization in immunohistochemical study was detected only in the nucleus of all tumor tissues. In brain tissues adjacent to tumor, immunohistochemical study for MPG was not stained both in the nucleus and in cytoplasm. CONCLUSION: These results suggest MPG's role in human astrocytic tumors and raise the possibility that the increased mRNA level and intracellular localization could be associated with astrocytic tumorigenesis. Further studies about control of MPG gene expression in astrocytic tumors are warranted.
Brain ; Carcinogenesis ; Cytoplasm ; DNA Repair* ; DNA* ; Gene Expression ; Humans ; Immunohistochemistry ; In Situ Hybridization ; RNA ; RNA, Messenger

A 49-year-old male patient was admitted with chief complaint of hemoptysis. Preoperative chest PA and CT scan revealed air-filled large cavitary lesion at the right upper lobe with typical meniscus sign. Serum anti-fungus antibody for Aspergillus was positive and he was diagnosed as aspergilloma. We planned RULobectomy but it was impossible due to severe pleural adhesion in apex and mediastinal pleura. Therefore, we performed a cavernostomy and serratus anterior muscle flap transposition in one stage. The patient recovered without complication and was followed up for 8 months without recurrence of hemoptysis.
Aspergillus ; Hemoptysis ; Humans ; Male ; Middle Aged ; Pleura ; Recurrence ; Thorax ; Tomography, X-Ray Computed

Krukenberg tumor of the ovary, originally described by Krukenberg as "Fibrosarcoma ovarii mucocellulare carcinomatodes", characterized as an infiltrative mucinous carcinoma of predominant signet-ring cell type, almost metastasize from gastrointestinal tract, is not common tumor. In recent years, we have experienced 2 cases of Krukenberg tumors on both ovaries metastasis from the stomach, and report these cases with brief review of the literatures.
Adenocarcinoma, Mucinous ; Female ; Gastrointestinal Tract ; Krukenberg Tumor* ; Neoplasm Metastasis ; Ovary ; Stomach ; Stomach Neoplasms

Nevus lipomatosus cutaneous superficialis is a very rare disorder characterized by nevoid fatty growth in the dermis. It usually arises in the pelvic girdle, so is unfamiliar to most otolaryngologists. A case of a 72-year-old male with nevus lipomatosus cutaneous superficialis in the nasal cavity is presented with a brief review of the disease.
Aged ; Dermis ; Humans ; Male ; Nasal Cavity ; Nevus*

This study is designed to detect the emperipolesis in megakaryocyte in fetal liver, which is an important organ of hemopoiesis, during rat development, and to compare the activity of erythropoiesis in fetal liver with that of emperipolesis in megakaryocyte. In order to find that which causes are more related to emperipolesis, we applied periodic acid Schiff reagent, which is special staining method for megakaryocyte and used electron microscope. The size and maturity of magakaryocyte gradually developed with age. The number of megakaryocyte increased in similar proportion to the activity of erythropoiesis. Emperipolesis occurred in more mature megakaryocyte (most stage III). The majority of cells enclosed within megakaryocyte, were the precursor of erythrocytes. Emperipolesis was observed for the first time at 14 day of gestation. The highest frequency of emperipolesis showed 20% of whole megakaryocyte at 16 day of gestation, when the activity of erythropoiesis was most vigorous. The frequency of emperipolesis began to decrease after then, but megakaryocyte was most numerous at 17 day of gestation during fetal and neonatal period. At 19 day of gestation, stage IV megakaryocytes, just before the stage producing platelet, began to appear. Megakaryocyte was not observed after postnatal 10 day. In conclusion, it was found that the emperipolesis in megakaryocyte occurred in the rat fetal liver and was extreme the emperipolesis most observed at the time of most vigorous erythropoiesis during the development of rat fetal liver. It is suggested that the frequency of emperipolesis within megakaryocyte is more closely related with the activity of erythropoiesis in fetal liver than the that of megakaryocytopoiesis, before bone marrow acts as an important organ of hematopoiesis. It is also suggested that the emperipolesis contributes to the production of platelet during gestation period and the maturation of erythrocyte.
Animals ; Blood Platelets ; Bone Marrow ; Emperipolesis* ; Erythrocytes ; Erythropoiesis ; Hematopoiesis ; Liver ; Megakaryocytes* ; Periodic Acid ; Pregnancy ; Rats ; Thrombopoiesis

Neurofibroma of the larynx is a rare disease. Endolaryngeal neurofibromas may take place as an isolated lesion or a part of multiple neurofibromatosis (von Recklinghausen's disease). A case of endolaryngeal neurofibroma was the first reported by Suchanek in 1925. Following the first report, there have been sporadic reports of endolaryngeal neurofibroma When the lesion is in the larynx, the major site is the aryepiglottic fold or the arytenoid, because the branch of the superior laryngeal nerve is involved. Rarely, a vocal cord is also concerned. Surgical excision is the treatment of choice. We report a case of isolated neurofibroma arising from the right true vocal cord.
Laryngeal Nerves ; Larynx ; Neurofibroma* ; Neurofibromatoses ; Rare Diseases ; Vocal Cords*

Acute visual loss may occur in association with sinusitis either as a complication of orbital cellulitis or, less frequently, as a part of the orbital apex syndrome. Originally, an orbital apex syndrome is associated with an affection of the vessels and nerves passing through the superior orbital fissure and the optic foramen. A classical feature of orbital apex syndrome is presented with visual loss and ophthalmoplegia, but with minimal or no signs of orbital inflammation such as proptosis, chemosis, or lid edema. We present a case of male patient with alternating bilateral visual loss with ophthalmoplegia secondary to paranasal sinusitis.
Edema ; Exophthalmos ; Humans ; Inflammation ; Male ; Ophthalmoplegia ; Orbit* ; Orbital Cellulitis ; Orbital Diseases ; Sinusitis*