1.Diagnostic Values of Abdominal Ultrasonograpy in Patients with Fever and Abdominal Symptoms.
Mi Kyung LEE ; Chang Sung IM ; Sun Mi AHN ; Chang Hi KIM ; Dong Jin LEE ; Joong Hyuck KWAN ; Yong Hoon PARK
Yeungnam University Journal of Medicine 1995;12(2):191-202
PURPOSE: Acute febrile illness in children frequently accompanies with abdominal symptoms such as vomiting, diarrhea, and abdominal pain, even if its etiology is not occured from the gastrointestinal tract. If the etiology of fever was unknown and the fever was accompanied with abdominal symptoms, we should be concerned about whether the etiology of fever was originated from the gastrointestinal tract or interpretated from the abnormality in the gastrointestinal tract. This study was performed to evaluate the diagnostic value of abdominal ultrasonography in patients with fever and abdominal symptoms. METHODS: We reviewed retrospectively the medical records of abdominal ultrasonographic (US) findings of 60 cases of acute febrile illness with abdominal symptoms at department of Pediatrics, Ulsan Dongang General RESULTS: (100%), splenomegaly in 4 cases (66.7%), ileocecitis in 1 case (16.7%), enlarged mesenteric lymph nodes and splenomegaly in 4 cases (66.7%), enlarged mesenteric lymph nodes, splenomegaly and ileocecitis in 1 cases (16.7%). 6) The enlarged mesenteric lymph nodes and the abnormalities around the appendix were seen in 7 cases (11.7%), which were confirmed as appendicitis all. 7) The thickening of wall in urinary bladder was seen in 2 cases (3.3%) of acute cystitis and acute hemorrhagic cystitis. 8) The subtle thickening of wall in colon was seen in 1 cases (1.7%) of shigellosis. CONCLUSIONS: The enlarged mesenteric lymph nodes, splenomegaly and ileocolitis on the abdominal ultrasonography in patients with fever and abdominal symptoms aree suggestive findings of typhoid fever. The enlarged mesenteric lymph nodes and the abnormalities around the appendix on abdominal ultrasonography make the rapid diagnosis of acute appendicitis and its complications, when physical examination is difficult in small children and diagnosis of their illnesses is obscure in patients with fever and abdominal pain.
Abdominal Pain
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Appendicitis
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Appendix
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Child
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Colon
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Crohn Disease
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Cystitis
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Diagnosis
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Diarrhea
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Dysentery, Bacillary
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Fever*
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Gastrointestinal Tract
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Humans
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Lymph Nodes
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Medical Records
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Pediatrics
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Physical Examination
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Retrospective Studies
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Splenomegaly
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Typhoid Fever
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Ulsan
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Ultrasonography
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Urinary Bladder
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Vomiting
2.Cardiac Involvement in Patients with Duchenne Muscular Dystrophy.
Sung Woo KWON ; Se Joong RIM ; Sung Woong KANG ; Jihyuk RHEE ; Jae Youn MOON ; Jong Kwan PARK ; Sung Ju LEE ; Chan Ik PARK ; Hai Jin KIM ; Young Won YOON ; Bum Kee HONG ; Hyuck Moon KWON ; Hyun Seung KIM
Journal of the Korean Society of Echocardiography 2005;13(4):152-158
BACKGROUND: Cardiac involvement in Duchenne muscular dystrophy (DMD) is common, but usually latent without symptoms or signs in the initial period of disease. This study investigated the incidence and predictor of cardiac involvement in DMD patients. METHOD: From January 2000 to June 2005, we enrolled 45 patients with DMD (aged 20.2+/-3.0 years) who admitted to the Yongdong Severance Hospital. Electrocardiography and transthoracic echocardiography was done to evaluate the cardiac function. RESULT: Electrocardiographic abnormalities were present in 80.1% of patients. Sinus tachycardia was most common (50%). LVEF was decreased (46.7+/-13.8%), and 56% of the patients had diastolic dysfunction. Patients with pulmonary involvement were older (20.7+/-3.8 vs 17.6+/-2.8 years, p=0.028), and patients with reduced LVEF (<50%) had longer duration of disease (11.4+/-4.4 vs 14.3+/-2.4 years, p=0.04). However, on multivariate analysis, age, duration of disease, pulmonary involvement, dyspnea symptom, electrocardiographic abnormality was not an independent predictor for LV systolic dysfunction in adolescent and adult patients with DMD. CONCLUSION: Cardiac involvement in adolescent and adult patients with DMD was frequently observed independent of age, duration of disease, pulmonary involvement, and dyspnea symptom. Therefore, more active cardiac investigation is required in patients with DMD, even without clinical suspicion.
Adolescent
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Adult
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Dyspnea
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Echocardiography
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Electrocardiography
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Humans
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Incidence
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Lung Diseases
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Multivariate Analysis
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Muscular Dystrophy, Duchenne*
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Tachycardia, Sinus
3.Lipoprotein-Associated Phospholipase A2 Is Related to Plaque Stability and Is a Potential Biomarker for Acute Coronary Syndrome.
Hyemoon CHUNG ; Hyuck Moon KWON ; Jong Youn KIM ; Young Won YOON ; Jihyuk RHEE ; Eui Young CHOI ; Pil Ki MIN ; Bum Kee HONG ; Se Joong RIM ; Ji Hyun YOON ; Sung Joo LEE ; Jong Kwan PARK ; Myung Hyun KIM ; Minhee JO ; Jeong Hee YANG ; Byoung Kwon LEE
Yonsei Medical Journal 2014;55(6):1507-1515
PURPOSE: Plasma lipoprotein-associated phospholipase A2 (Lp-PLA2) binds to low-density lipoprotein. The levels of Lp-PLA2 reflect the plaque burden, and are upregulated in acute coronary syndrome (ACS). We investigated the diagnostic value of Lp-PLA2 levels and found that it might be a potential biomarker for ACS. MATERIALS AND METHODS: We classified 226 study participants into three groups: patients without significant stenosis (control group), patients with significant stenosis with stable angina (SA group), and patients with ACS (ACS group). RESULTS: Lp-PLA2 and high-sensitivity C-reactive protein (hs-CRP) levels were significantly greater in the ACS group than in the SA group (p=0.044 and p=0.029, respectively). Multivariate logistic regression analysis revealed that Lp-PLA2 levels are significantly associated with ACS (odds ratio=1.047, p=0.013). The addition of Lp-PLA2 to the ACS model significantly increased the global chi2 value over traditional risk factors (28.14 to 35.602, p=0.006). The area under the receiver operating characteristic curve for Lp-PLA2 was 0.624 (p=0.004). The addition of Lp-PLA2 level to serum hs-CRP concentration yielded an integrated discrimination improvement of 0.0368 (p=0.0093, standard error: 0.0142) and improved the ability to diagnose ACS. CONCLUSION: Lp-PLA2 levels are related to plaque stability and might be a diagnostic biomarker for ACS.
1-Alkyl-2-acetylglycerophosphocholine Esterase/*blood
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Acute Coronary Syndrome/*blood/physiopathology
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Aged
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Aged, 80 and over
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Angina Pectoris
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Biological Markers/blood
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C-Reactive Protein/*metabolism
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Coronary Angiography
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Female
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Humans
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Lipoproteins, LDL/*blood
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Logistic Models
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Male
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Middle Aged
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Multivariate Analysis
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Plaque, Atherosclerotic/blood
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ROC Curve
;
Risk Factors