Fetal echocardiography is used by means of decleration of fetal cardiac anaztomy, to estabilish the diagnosis of congenital heart disease in utero. We attemped fetal echocardiography to ninty three pregnant women after intra uterine period 24 weeks, and estimated cardiac circumference, cardiac axis, pulmonary atery root diameter, arortic root diameter, diameter of inferior vena cava, diameter of superior ve studied how these estimates associate with following gestational na cava, and fractional shortening of ventricles. We ages. Cardiac axis was on the average 37.28 degree and cardiac apex was located in anterior left side of chest area. Aortic root diameter was 0.227 GA-0.043mm (GA=gestational age) at systolic phase, 0.203 GA+0.421mm at diastolic phase. Pulmonaly root diameter was 0.271 GA-0.029mm at systolic phase, 0.251 GA-0.067mm at diastolic phase. Thoracic aorta diameter was 0.195 GA+0.109mm at systolic phase, 0.198 GA+0.794mm at diastolic phase. Fractional shortening was 0.24 (1 Standard Deviation=0.11) in right ventricle, 0.23(1 SD=0.154) at left ventricle, and so ratio of right and left ventricle was 1.04(1 SD=0.51). Once normal fetal cardiac anatomy is understood, structural defects and/or alternation of function can be evaluated antenatally.
Aorta, Thoracic ; Axis, Cervical Vertebra ; Diagnosis ; Echocardiography* ; Female ; Heart Defects, Congenital ; Heart Ventricles ; Humans ; Pregnant Women ; Thorax ; Vena Cava, Inferior

A case of contact dermatitis due to herb onintment is described in a 24 year-old female patient. After topical application of herb ointment, she developed erythematous papules and plaques on the face and neck. Patch test revealed positive reactions to ammoniated mercury, thimerosal, and the herb ointment. Energy-dispersive X-ray microanalysis of the herb ointment showed a striking peak for mercury.
Dermatitis, Contact* ; Electron Probe Microanalysis ; Female ; Humans ; Neck ; Patch Tests ; Strikes, Employee ; Thimerosal ; Young Adult

No abstract available.
Bell Palsy* ; Gadolinium* ; Herpes Zoster Oticus* ; Herpes Zoster* ; Magnetic Resonance Imaging*

The authors reviewed the cases of 12 children with unilateral motor weakness after minor head injury who were treated between 1990 and 1996. Eight were boys and four were girls, and all were less than seven years old (range, 8 month to 6years) ; unilateral weakness developed immediately after an apparently minor head injury. Computed tomography and MR scanning disclosed an ischemic lesion at one side of the basal ganglia. Most children recovered. The mechanism by which this ischemic lesion develops at the basal ganglia is not known. In children, however the angle between the middle cerebral artery and lateral perforating vessels is more acute than in the adult, and we believe that after minor head injury, stretching and distorting the angle of these perforating branches may lead to'unknown vessel change', with a consequent decrease in local blood flow. The end result is an ischemic lesion in the basal ganglia.
Adult ; Basal Ganglia ; Child* ; Craniocerebral Trauma ; Female ; Humans ; Ischemia* ; Middle Cerebral Artery

No abstract available.
Cesarean Section* ; Female ; Fetal Blood* ; Humans ; Infant, Newborn* ; Pregnancy

OBJECTIVES: Cord blood stem cells have been widely used as donor cells for bone marrow transplantation recently. These cells can give rise to a variety of hematopoietic lineages to repopulate the blood. Recent observations reveal that some bone marrow cells and bone marrow stromal cells(MSCs) can grow to become either neurons or glial cells. It is, however, unclear whether or not there exists stems cells which can differentiate into neurons in the blood during the early stages of postnatal life. METHODS: Human cord blood stem cells were prepared from human placenta after full term delivery. To induce neuronal differentiation of stem cells, beta-mercaptoethanol was treated. To confirm the neuro-glial characteristics of differentiated stem cells, immunocytochemical stain for NeuN, neurofilament, glial fibrillary acidic protein(GFAP), microtubule associated protein2(MAP2) was performed. RT-PCR was performed for detecting nestin mRNA and MAP2 mRNA. RESULTS: We showed in this experiment that neuro-glial markers(NeuN, neurofilament, MAP2, GFAP) were expressed and axon-like cytoplasmic processes are elaborated in the cultured human cord blood stem cells prepared from new born placenta after full term delivery. Nestin mRNA was also detected in fresh cord blood monocytes. Conclusions: These results suggest that human cord blood derived stem cells may be potential sources of neurons in early postnatal life.
Bone Marrow ; Bone Marrow Cells ; Bone Marrow Transplantation ; Cytoplasm ; Fetal Blood* ; Humans* ; Microtubules ; Monocytes ; Nestin ; Neural Stem Cells ; Neuroglia ; Neurons ; Placenta ; RNA, Messenger ; Stem Cells ; Tissue Donors ; Umbilical Cord*

The Dandy-Walker syndrome is a developmental disorder of the brain characterized by cystic dilatation of the fourth ventricle and agenesis or hypoplasia of the cerebellar vermis. We experinced a case of Dandy-Walker syndrome with complex cardiac anomaly in female newborn who presented with apnea at birth. Physical examination showed coloboma on left eye, low estting malformed ear, and high arched palate. Autopsy revealed cystic dilatation of the fourth ventricle with secondary loss of cerebellar vermis. The floor of the fourth ventricle is exposed through this defect. Heart showed aortic atresia and univentricular heart. The case is reported with the review of the literatures.
Apnea ; Autopsy ; Brain ; Coloboma ; Dandy-Walker Syndrome* ; Dilatation ; Ear ; Female ; Fourth Ventricle ; Heart ; Humans ; Infant, Newborn ; Palate ; Parturition ; Physical Examination

No abstract available.
Sperm Motility* ; Spermatozoa*

Since the advent of extracorporeal shock wave lithotripsy(ESWL) provided an opportunity for a non-invasive method of treating urinary stones, it has been widely accepted that the ESWL is highly effective modality as the first line treatment method for the most urinary stones. However, there are still some controversies in establishing therapeutic strategy for the cases of large volume renal stones and lower ureteral stones. To evaluate the effectiveness of ESWL for these stones, comparative study about ESWL was performed with percutaneous nephrolithotomy(PNL) for the large volume renal stones and with ureteroscopic stone removal(URS) for the lower ureteral stones. For renal stone larger than 2.5 cm in long axis and lower ureteral stone, a total of 538 patients (542 organs) underwent treatment with ESWU using EDAP LT-01 machine) as outpatientbasis, PNL and URS under general anesthesia with admission from February in 1988to July in 1995. The patients were 318 in male and 220 in female. The average age of patient was 44.4 years, with the range of 10 to 81 years. The selection of treatment modality were decided largely by patients with their preference among the given options and with their economic status. They were analysed with respect to stone free rate, auxiliary procedure, complication, treatment duration and cost. The results were as follows ; 1. For renal stone larger than 2.5 cm in long axis, ESWL was undergone in 77 cases. The stone free rate was 63.6%(47.4% for the staghorn stones, 69.0% for the large renal stones excluding staghorn calculi). Mean time lost from work was 15.9+/-9.7 days(19.4+/-10.8 days for the staghorn stones, 14.8+/-9.1 days for the large renal stones excluding staghorn calculi). Mean treatment expense was 1,065,320 won. Complications that need additional treatment were occurred in 20.8%(21.2% for the staghorn stones, 20.7% for the large renal stones excluding staghorn calculi). PNL was performed in 42 cases. The stone free rate was 78.6%(55.6% for the staghorn stones, 84.8% for the large renal stones excluding staghorn calculi). Mean time lost from work was 19.8+/-3.7 days(20.4+/-4.7 days for the staghorn stones, 17.1+/-3.2 days for the large renal stones excluding staghorn calculi). Mean treatment expense was 911,390 won. Complications that need additional treatment were occurred in 28.6%(33.3% for the staghorn stones, 27.3% for the large renal stones excluding staghorn calculi) (Table 1). 2. For lower ureteral stone, ESWL was undergone in 214 cases. The stone free rate was 97.2%. Mean time lost from work was 3.2+/-2.1 days. Mean treatment expense was 645,680 won. Complications that need additional treatment were occurred in 4.7%. URS was performed in 209 cases. The stone free rate was 96.7%. Mean time lost from work was 10.8+/-3.2 days. Mean treatment expense was 701,850 won. Complications that need additional treatment were occurred in 7.2% (Table 2). For large volume renal stones excluding staghorn calculi, ESWL monotherapy resulted 15.8% less stone free rate than PNL monotherapy. For lower ureteral stone, ESWL was as effective as URS with respect to stone free rate and treatment expense. Moreover, time lost from work of ESWL cases was shorter than that of URS cases. Conclusively, it could be suggested that ESWL monotherapy is effective and preferentially applicable method for the lower ureteral stones and large volume renal stones excluding staghorn calculi. Whereas, it is not effective for the staghorn calculi.
Anesthesia, General ; Axis, Cervical Vertebra ; Calculi ; Female ; Humans ; Lithotripsy* ; Male ; Shock* ; Ureter* ; Ureteroscopy ; Urinary Calculi

No abstract available.
Uterus*