1.Expression of p-glycoprotein on human bladder transitional cell carcinoma.
Sung Koo JANG ; Joo Hee LEE ; Joon Woong SON ; Choong Hyun LEE ; Jin Il KIM ; Soo Yong CHAE
Journal of the Korean Cancer Association 1993;25(2):268-275
No abstract available.
Carcinoma, Transitional Cell*
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Humans*
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P-Glycoprotein*
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Urinary Bladder*
2.Primary Cutaneous Mucinous Carcinoma on the Abdomen.
In Pyeong SON ; Woo Sun JANG ; Jin Woong LEE ; Beom Joon KIM ; Myeung Nam KIM ; Kye Yong SONG
Korean Journal of Dermatology 2011;49(4):348-352
Primary cutaneous mucinous carcinoma is a rare epithelial neoplasm that arises from the deepest portion of the eccrine duct. It most commonly occurs on the scalp and face with a preference for on the eyelids. The histopathologic characteristics are large mucinous pools with fibrous septae and clusters of tumor cells. We report here on a case of mucinous carcinoma that developed on the abdomen of a 47-year-old woman.
Abdomen
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Adenocarcinoma, Mucinous
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Eyelids
;
Female
;
Humans
;
Middle Aged
;
Mucins
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Neoplasms, Glandular and Epithelial
;
Scalp
3.Primary Cutaneous Mucinous Carcinoma on the Abdomen.
In Pyeong SON ; Woo Sun JANG ; Jin Woong LEE ; Beom Joon KIM ; Myeung Nam KIM ; Kye Yong SONG
Korean Journal of Dermatology 2011;49(4):348-352
Primary cutaneous mucinous carcinoma is a rare epithelial neoplasm that arises from the deepest portion of the eccrine duct. It most commonly occurs on the scalp and face with a preference for on the eyelids. The histopathologic characteristics are large mucinous pools with fibrous septae and clusters of tumor cells. We report here on a case of mucinous carcinoma that developed on the abdomen of a 47-year-old woman.
Abdomen
;
Adenocarcinoma, Mucinous
;
Eyelids
;
Female
;
Humans
;
Middle Aged
;
Mucins
;
Neoplasms, Glandular and Epithelial
;
Scalp
4.The Occurrence of a Branchial Cleft Cyst in the Anterior Mediastinum: A Case Report.
Seong Hoon PARK ; Seong Hoon KIM ; Hyun Woong SHIN ; Hyun Chul JO ; Mi Yung SON ; Joon Hyuk GONG
Journal of the Korean Radiological Society 2008;59(2):107-110
Branchial cleft cysts and branchial anomalies develop from the branchial cleft apparatus that persists after fetal development. The most common anatomical site for the occurrence of branchial cleft cysts is in the cervical area, generally anterior to the sternomastoid muscle in the upper or middle portion of the neck. A mediastinal branchial cleft cyst is extremely rare and few cases have been reported. We report the case of branchial cleft cyst found in the anterior mediastinum with literature review.
Branchial Region
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Branchioma
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Fetal Development
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Mediastinal Cyst
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Mediastinum
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Muscles
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Neck
;
Thorax
;
Tomography, X-Ray Computed
5.Sorafenib (Nexavar(R), BAY 43-9006)-induced Hand-foot Skin Reaction with Facial Erythema.
Dong Ha KIM ; In Pyeong SON ; Jin Woong LEE ; Hye In LEE ; Beom Joon KIM ; Myeung Nam KIM
Annals of Dermatology 2011;23(1):119-122
Sorafenib (Nexavar(R), BAY 43-9006) is a novel, orally administered multi-kinase inhibitor that has recently been approved for the treatment of metastatic renal cell carcinoma. It is also used to delay disease progression in patients with advanced solid organ malignancies and metastatic melanoma. Sorafenib is associated with a relatively high incidence of dermatologic adverse events. The commonly occurring dermatologic adverse events associated with sorafenib include hand-foot skin reaction, facial erythema, splinter subungual hemorrhages, alopecia, pruritus and xerosis. We report here on a case of a 50-year-old man who was diagnosed with metastatic hepatocellular carcinoma. He developed both facial erythema and hand-foot skin reaction after the administration of sorafenib.
Alopecia
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Bays
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Carcinoma, Hepatocellular
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Carcinoma, Renal Cell
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Disease Progression
;
Erythema
;
Hemorrhage
;
Humans
;
Incidence
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Melanoma
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Middle Aged
;
Niacinamide
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Phenylurea Compounds
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Pruritus
;
Skin
6.Non-amputative Surgical Management of Subungal Melanoma in Situ.
Min Gun YOO ; Byoung Joon SO ; Hee Joo KIM ; Gil Soo SON ; Jong Woong PARK ; Il Hwan KIM
Korean Journal of Dermatology 2013;51(4):265-267
Subungual melanoma is a variant of acral lentiginous melanoma and is thought to carry a poor prognosis due to difficulties in early diagnosis. Classical management of subungual melanoma is based on the radical surgery of distal phalanx amputation. Instead, conservative treatment with non-amputative wide excision of the nail unit followed by reconstruction has been insufficiently reported, especially in Korea. A 71-year-old woman presented with dark brownish longitudinal bands on her right thumbnail. Punch biopsies from the nail matrix and nail bed showed proliferation of atypical melanocytes without dermal involvement. We describe a case of subungual melanoma in situ of the right thumb, and a non-amputative surgical management which aims to provide adequate clearance of the lesion with minimal morbidity and satisfactory preservation of function for the patient.
Amputation
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Biopsy
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Early Diagnosis
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Female
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Humans
;
Korea
;
Melanocytes
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Melanoma
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Nails
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Prognosis
;
Thumb
7.Internet of Things-Based Behavioral Intervention for Older Adults with Major Depressive Disorder: Preliminary Study
Hyo Jin HAN ; Chang Hyung HONG ; Jae Hoon KIM ; Hyun Woong ROH ; Sang Joon SON
Journal of Korean Geriatric Psychiatry 2019;23(1):14-19
OBJECTIVE: To assess the effectiveness of Internet of Things (IoT)-based behavioral intervention for reducing depressive symptom of older adults with major depressive disorder. METHODS: A 12-week randomized cross-over controlled study was conducted at community mental health center. We recruited 39 participants with major depressive disorder aged 60 years or older. As a multidomain intervention, four evidence-based therapeutic factors (physical activity, healthy diet, social activity, and emotional regulation) were approached. To maintain motivation of participants, we applied contingency management using IoT device based on operant conditioning theory. RESULTS: The primary outcome was change of depressive symptom measured by Montgomery-Asberg Depression Rating Scale (MADRS). Mixed-effect model compared the effectiveness of intervention and usual care management (intervention by time and period interaction, p=0.017). And during the study period consisting of a total of visit 8, significant group difference was shown in post hoc test at visit 4 (MADRS score of intervention group : MADRS score of control group=7.7±3.4 : 21.1±11.5, p=0.008). CONCLUSION: Community-implementable IoT-based behavioral intervention resulted in greater reduction of depressive symptom of elderly with major depressive disorder.
Adult
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Aged
;
Conditioning, Operant
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Depression
;
Depressive Disorder, Major
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Diet
;
Humans
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Internet
;
Mental Health
;
Motivation
9.The Etiological Role of Legionella Pneumophila in Patients with Community-Acquired Pneumonia in Korea.
Hong Seok SONG ; Ji Hyeon SUH ; Jong Ho AHN ; Byeong In YOON ; Seung Joon LEE ; Myung Goo LEE ; Man Jo JUN ; Min Jong KANG ; Jae Myung LEE ; Dong Gyu KIM ; Jee Woong SON ; Myung Jae PARK ; In Gyu HYUN ; Ki Suck JUNG
Tuberculosis and Respiratory Diseases 2001;50(4):409-414
BACKGROUND: Legionella pneumophila has been recognized as an important cause of community-acquired pneumonia(CAP) requiring hospitalization. However, epidemiological data on the occurrence of legionella-related pneumonia is unavailable in Korea. The purpose of this study was to evaluated the etiological imprtance of legionella pneumophila serogroup 1 in patients hospitalized with CAP. METHOD: The CAP patient over 16 year-old were recruited from July 1999 to June 2000 at the Chunchon Sacred Heart Hospital. Fifty four patients (male 29, female 25, average age 63.8±15.3) were included in this study. A diagnosis of a legionella pneumophila infection was based on a urinary antigen test using the Binax Company enzyme immunoassay. The severity of pneumonia was assessed using the Fine's PORT scoring system. RESULT: The average Fine's PORT score was 99.7(±44.9). According to the risk classification proposed by the Infectious Disease Society of America, the number of patients in each class(from class I to class V) were 6(11.1%), 13(24.1%), 9(16.7%), 14(25.8%), and 12(22.2%), respectively. Thirty two patients(59.3%) were initially admitted to the intensive care unit. The mortality rate was 16.7%(9 in 54). In all patients, urinary antigens to Legionella pneumophila serogroup 1 were not detected. CONCLUSION: Legionella pneumophila may play little role in causing adult CAP in Korea. Therefore, the routine use of macrolide in the empirical treatment of the CAP patients based upon the ATS guidelines(1993) in Korea should be reevaluated.
Adult
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Americas
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Classification
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Communicable Diseases
;
Diagnosis
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Female
;
Gangwon-do
;
Heart
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Hospitalization
;
Humans
;
Immunoenzyme Techniques
;
Intensive Care Units
;
Korea*
;
Legionella pneumophila*
;
Legionella*
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Legionnaires' Disease
;
Mortality
;
Pneumonia*
10.The Relationship between Temporal Discounting and Well-Being in the Elderly.
Seok Joo HONG ; Ki Jung CHANG ; Hyun Woong ROH ; Jai Sung NOH ; Young Ki CHUNG ; Ki Young LIM ; Chang Hyung HONG ; Sang Joon SON
Journal of Korean Geriatric Psychiatry 2016;20(1):33-37
OBJECTIVE: This study aims to examine association of temporal discounting with well-being of Korean community-dwelling elderly. METHODS: The subjects of this research were 4,373 community-dwelling older persons without dementia. Each subject was administered the questionnaires regarding the socio-demographic characteristics, temporal discounting which was measured using standard questions in which participants were asked to choose between an immediate, smaller payment and a delayed, larger one. Outcome variable is Korean version of the World Health Organization Five Well-Being Index (WHO-5). Statistical analyses including the Pearson's correlation test and logistic regression were performed in this study. RESULTS: At baseline, temporal discounting was negatively associated with WHO-5 in the Pearson's correlation test (r=-0.04, p=0.006). In a adjusted model for confounding variables, temporal discounting was negatively associated with WHO-5 [odd ratio (95% confidence interval)=0.57 (0.35–0.92), p=0.021]. CONCLUSION: Elderly individual with a higher temporal discounting (which indicates impulsivity) may have a lower quality of life.
Aged*
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Confounding Factors (Epidemiology)
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Dementia
;
Humans
;
Logistic Models
;
Quality of Life
;
World Health Organization