No abstract available.
Humans ; Osteosarcoma*

Epithelioid hemangioendothelioma(EH) is a low-grade tumor of vascular endothelial cell origin, which most commonly occur in the lower extremities of middle-aged patients with an equal gender distribution. It may occur on internal organs such as the liver or lung or bones. A 54-year-old woman who had a history of metastatic adenocarcinoma of unknown origin on the right inguinal lymph node, was presented to us because of a 1.0 x 1.0cm-sized and 2 x 2cm-sized two subcutaneous nodule on her right shin. On H & E stain, there were nests of round nucleated, polygonal, vacuolated cells, some of which contained fragmented erythrocytes. Factor VIII related antigen, CD31 was positive. A diagnosis of epithelioid hemangioendothelioma was established based on histologic, immunohistochemical studies. Wide excision was performed. There was no recurrence nor the development of new lesions so far.
Adenocarcinoma ; Diagnosis ; Endothelial Cells ; Erythrocytes ; Female ; Hemangioendothelioma, Epithelioid* ; Humans ; Liver ; Lower Extremity ; Lung ; Lymph Nodes ; Middle Aged ; Recurrence ; von Willebrand Factor

No abstract available.
Adenocarcinoma*

No abstract available.
Cleft Lip* ; Diagnosis* ; Ultrasonography*

This report details a case of 8-year-old girl showing failure of odontogenesis after chemo-radiation therapy for rhabdomysarcoma at the age of 4. The observed results were as follows ; 1. Past history revealed that she had received for a total radiation dose od 4430cGy, 29 fractions in 6 weeks and chemotherapy with vincristine, actinomycin D and cytoxan, followed as maintenance phase for 2 years. 2. The patient was symptom-free and appointed for the treatment of multiple dental caries. 3. Oral examination showed hypoplastic enamel on whole erupted permanent teeth and showed retarded eruption. 4. Conventional radiograms showed failure of root development including abrupt cessation of root formation and root agenesis, and microdobtia, missing teeth, irregular enamel, dislocation of the impacted teeth. Additional finding showed good healing bone pattern on the left mandibular ramus and angle area. 5. Cehalometric analysis revealed failure of bite raising due to incomplete eruption of all the first molars and made it possible to suspect entrapped mandibular growth and then Class II tendency growth. 6. There was correlation between the time of chemo-radiation therapy and the damage of the teeth.
Child ; Cyclophosphamide ; Dactinomycin ; Dental Caries ; Dental Enamel ; Dental Enamel Hypoplasia ; Diagnosis, Oral ; Dislocations ; Drug Therapy ; Female ; Humans ; Molar ; Odontogenesis* ; Rhabdomyosarcoma* ; Tooth ; Tooth, Impacted ; Vincristine

The purpose of this study was to aid in the prediction of tumor cell tolerance to radiotherapy and/or chemotherapy. For this study, cell surviving curves were obtained for human squamous cell carcinoma KB cell line after radiation exposure and/or administration of antitumor drugs. 2, 4, 6, 8 10Gy were irradiated at a dose rate of 210Gy/min using 60Co Irradiator ALDORADO 8. After irradiation, KB cell lines(3*104cells/ml) were exposed to 2 /ml of bleomycin ir cisplatin for 1 hour. The viable cells were determined by MTT assay for each radiation dose and/or each drug at the 4th day. And they were compared to control values. The obtained results were as follows ; 1. The slope of the surviving curve after irradiation of 2, 4, 6, 8, 10Gy on KB cell line was relatively steep. 2. There was no significant difference between ths cytotoxicity of bleomycin compared to control group. But, there was significant difference between the cytotoxicity of cisplatin compared to control group. And the cytotoxicity of cisplatin was greater than that of bleomycin on KB cell line. 3. There were dignificant differences of surviving fractions after irradiation of 2Gy and 10Gy with 2 /ml of bleomycin compared with the groups of irradiation only on KB cell line. 4. There were significant differences of surviving fractions after irradiation of 2, 4, 6, 8, 10Gy with 2 /ml of cisplantin compared with the groups of irradiation only on KB cell line. 5, There was significant difference of surviving fraction between groups after irradiation of 10Gy with 2 /ml of bleomycin and cisplatin.
Antineoplastic Agents ; Bleomycin ; Carcinoma, Squamous Cell ; Cisplatin ; Drug Therapy ; Humans ; KB Cells* ; Radiation Tolerance* ; Radiotherapy

PURPOSE: Sling procedures have become the gold standard for treating all types of stress urinary incontinence (SUI) in women because of their simplicity of procedure and good outcomes. We compared the outcomes of anterior vaginal wall sling with cadaveric fascia lata sling. MATERIALS AND METHODS: Between October 1996 and April 2000, 43 women with SUI who were treated with anterior vaginal wall sling and 23 women with SUI who were treated with cadaveric fascia lata sling were analyzed. Mean follow-ups were 43.0 months (29-56) for anterior vaginal wall sling and 21.5 months (16-30) for cadaveric fascia lata sling. All patients were evaluated preoperatively with a detailed history, pelvic examination, urinalysis, voiding diary, and urodynamic study including Valsalva leak point pressure. Parameters of comparison included presence of stress incontinence, length of hospital stay, duration of catheterization, operation time, and complication and success rates. RESULTS: The success rates, including satisfaction rates, were 83.7% in the anterior vaginal wall sling group and 82.6% in the cadaveric fascia lata sling group. The complication rates were 23.3% in the anterior vaginal wall sling group and 26.1% in the cadaveric fascia lata sling group. CONCLUSIONS: Both procedures were equally effective in the management of female SUI with high cure rates and acceptably low complication rates. However, further long-term follow-up study of these procedures is required to determine the persistence of the good results in women with SUI.
Cadaver* ; Catheterization ; Catheters ; Fascia Lata* ; Fascia* ; Female* ; Follow-Up Studies ; Gynecological Examination ; Humans ; Length of Stay ; Urinalysis ; Urinary Incontinence* ; Urodynamics

PURPOSE: Although the pudendal nerve terminal motor latency (PNTML) is normally used, there is no definite test that accurately reflects the function of the pudendal nerve. This study was undertaken to determine the relative accuracy of the various methods in measuring the function of the pudendal nerve. METHODS: Thirty one female patients (age 51.3+/-15.7) with a defecation disorder (constipation 20, fecal incontinence 11) were evaluated prospectively using a neurophysiologic test and balloon reflex manometry. Five parameters such as the right and left PNTML, anal mucosal electrosensitivity, latency and the amplitude of the rectoanal contractile reflex (RACR) were analyzed statistically for their correlation. RESULTS: There was no significant inter-test correlation among the parameters. However, the intra-test correlations between the parameters such as the right and left PNTML (r=0.9629, P<0.001)/latency and the RACR amplitude (r= -0.3770, P=0.0366) were found to be significant. CONCLUSION: The accuracy of these tests in evaluating the pudendal neuropathy could not be determined. However, because it can be assumed that a measurement of the RACR in addition to RNTML is technically accurate, it there will need to be more study for it to be used as an alternative to a PNTML measurement.
Defecation ; Fecal Incontinence ; Female ; Humans ; Manometry ; Prospective Studies ; Pudendal Nerve* ; Pudendal Neuralgia ; Reflex

The incidence of colorectal cancer in Korea has increased dramatically over the past few decades. According to the National Cancer Registry, the age-standardized incidence rates increased from 27.1 to 44.5 per 100,000 for men and from 17.2 to 24.3 per 100,000 for women between 1999 and 2007. The overall incidence of colorectal cancer increased by 7.0% annually in men and 5.3% in women from 1999 to 2007, while the incidence rates of the most common cancers, such as stomach and liver cancers, decreased during the same period. Epidemiologic studies have suggested that higher intakes of red and processed meat, a lack of physical activity, obesity, and alcohol drinking are risk factors for colorectal cancer. During the past few decades, significant socio-economic changes have taken place in Korea with respect to the economy, industrial structure, dietary habits, physical activity, and prevalence of obesity. Changes in dietary habits and lifestyle-related factors are believed to be the reasons for the increase in the incidence of colorectal cancer in Korea.
Alcohol Drinking ; Colonic Neoplasms ; Colorectal Neoplasms ; Epidemiologic Studies ; Female ; Food Habits ; Humans ; Hypogonadism ; Incidence ; Korea ; Life Style ; Liver Neoplasms ; Male ; Meat ; Mitochondrial Diseases ; Motor Activity ; Obesity ; Ophthalmoplegia ; Prevalence ; Risk Factors ; Stomach

Many types of upper lip reconstruction have been introduced to treat defects after a tumor excision or trauma. The authors treated two cases of upper lip defects. A 35-year-old woman presented with a squamous cell carcinoma of the left upper lip that had invaded the corner of the mouth. After resecting the tumor, the defect was 3.7x3.5 cm in size. A 52-year-old woman presented with a dog bite of the right upper lip. The defect measured 4.0x2.2 cm in size. The two cases were reconstructed by combined rotation and advancement of a cheek flap. This technique produced a good functional outcome that allowed for oral competence and created an opening of adequate size. A combination of rotation and an advancement flap can be used to treat upper lip defects in a single-stage procedure. This approach produces a good functional and cosmetic outcome.
Adult ; Animals ; Bites and Stings ; Carcinoma, Squamous Cell ; Cheek ; Cosmetics ; Dogs ; Female ; Humans ; Lip ; Mental Competency ; Middle Aged ; Mouth ; Surgical Flaps