1.Effect of Clonidine on the Blood Pressure, Heart Rate and Plasma Catecholamine Concentration during General Anesthesia.
Chong Dal CHUNG ; Kyung Joon LIM ; Kwang Soo SONG
Korean Journal of Anesthesiology 1997;33(2):336-341
BACKGROUND: Induction of general anesthesia with tracheal intubation and skin incision are potent stimuli that can induce increased sympathetic activity, heart rate and blood pressure. We compared the hemodynamic response and catecholamine concentration during general anesthesia with intravenous clonidine pretreatment, a centrally acting -2 adrenoceptor agonist, and without pretreatment. METHODS: Forty ASA I or II patients aged from 20 to 60 years undergoing elective surgery were randomly allocated to two groups. In group I, 5 ml of 0.9% normal saline as control administered intravenously 10 minutes before induction of anesthesia, and anesthesia was induced with thiopental sodium, succinylcholine and maintained with N2O (2.5L/min)-O2 (2.5L/min)-enflurane (1.3~1.8 vol%). In group II, 4 g/kg clonidine diluted in 5ml of normal saline administered intravenously 10 minutes before induction of anesthesia, and anesthesia was induced with thiopental sodium, succinylcholine and maintained with N2O-O2-enflurane (0.5~1.0vol%) and 2 g/kg/hr clonidine was continuously infused. We measured blood pressure, heart rate and plasma catecholamine at preinduction, 1 minute after intubation (T1), 1 (T2) and 30 minutes after skin incision (T3) and compared with group I. RESULTS: There was statistical significance in systolic and diastolic pressure at T1 between two groups. There was statistical significance in heart rate, epinephrine and norepinephrine at T1, T2 and T3 between two groups. CONCLUSION: The elevation of blood pressure, heart rate and plasma catecholamine accompanying tracheal intubation and skin incision may be prevented by administration of intravenous clonidine.
Adult
;
Anesthesia
;
Anesthesia, General*
;
Blood Pressure*
;
Brain
;
Clonidine*
;
Epinephrine
;
Heart Rate*
;
Heart*
;
Hemodynamics
;
Hemorrhage
;
Hope
;
Humans
;
Incidence
;
Intubation*
;
Larynx
;
Male
;
Norepinephrine
;
Plasma*
;
Skin
;
Spondylitis, Ankylosing
;
Succinylcholine
;
Thiopental
2.Acute myocardial infarction caused by high voltage electrical injury.
Boo Soo LEE ; Sung Oh HWANG ; Kyoung Soo LIM ; Tae Joon PAEK ; Yoon Kyu JUNG
Journal of the Korean Society of Emergency Medicine 1993;4(1):122-126
No abstract available.
Myocardial Infarction*
3.Clinical study of group B streptococcal infection in infants less than two months of age.
Hee Jeong AHN ; Ji Yeon LIM ; Sung Hee OH ; In Joon SEOL ; Soo Jee MOON ; Hahng LEE
Journal of the Korean Pediatric Society 1992;35(1):17-25
No abstract available.
Humans
;
Infant*
;
Streptococcal Infections*
4.The First Neurosurgical Analysis of 8 Korean Children with Sotos Syndrome.
Journal of Korean Neurosurgical Society 2008;44(4):240-244
OBJECTIVE: Sotos Syndrome is characterized by macrocephaly, overgrowth, and developmental delay, and more than 300 patients have been reported worldwide to date. The authors reviewed the clinical characteristics of 8 patients with Sotos Syndrome in Korea for a new understanding and treatment strategies. METHODS: The medical records of a total of eight Korean children with Sotos Syndrome were reviewed. All patients underwent developmental checkup, lumbar punctures for measurement of intracranial pressure (ICP), brain and spine magnetic resonance imaging and computerized tomography. RESULTS: All 8 patients showed macrocephaly and the characteristic craniofacial features of Sotos Syndrome. Other clinical characteristics shown were overgrowth (7/8), developmental delay (7/8), congenital heart defect (3/8), flat foot (8/8), scoliosis (4/8), spina bifida (8/8), hydrocephalus (4/8), cavum vergae (3/8), and increased subdural fluid collection (5/8). Mean ICP measured via lumbar puncture was 27.35+/-6.25 cm H2O (range 20 to 36 cm H2O). Two patients received ventriculo-peritoneal shunt, and 1 patient underwent subduro-peritoneal shunt with improvement. Spinal orthosis was applied to 4/5 patients with scoliosis and 4/8 children with flat foot were provided with foot orthosis. CONCLUSION: In this first Korean study of 8 Sotos Syndrome patients we demonstrated the presence of spina bifida and increased ICP, which had not been previously described. The authors therefore suggest that all patients with Sotos Syndrome should undergo examination for the presence of spina bifida, and that shunt procedures would improve development and alleviate clinical symptoms.
Brain
;
Child
;
Flatfoot
;
Foot Orthoses
;
Heart Defects, Congenital
;
Humans
;
Hydrocephalus
;
Intracranial Pressure
;
Korea
;
Macrocephaly
;
Magnetic Resonance Imaging
;
Medical Records
;
Orthotic Devices
;
Scoliosis
;
Sotos Syndrome
;
Spinal Dysraphism
;
Spinal Puncture
;
Spine
;
Ventriculoperitoneal Shunt
5.Optimal locations and travelling pathways of emergency ambulances in Wonju city.
Moo Eob AHN ; Kyoung Soo LIM ; Sung Oh HWANG ; Seong Joon KANG
Journal of the Korean Society of Emergency Medicine 1993;4(1):67-77
No abstract available.
Ambulances*
;
Emergencies*
;
Gangwon-do*
6.Analysis of korean disaster plan with the review of three cases of disasters.
Moo Eob AHN ; Sung Oh HWANG ; Kyoung Soo LIM ; Sung Joon KANG
Journal of the Korean Society of Emergency Medicine 1993;4(2):27-39
No abstract available.
Disasters*
7.Diagnosis of chest injury by abdominal CT scan in multiple injured patients.
Moo Ub AHN ; Sung Oh HWANG ; Kyoung Soo LIM ; Joong Hwan OH ; Seong Joon KANG
Journal of the Korean Society of Emergency Medicine 1991;2(1):91-98
No abstract available.
Diagnosis*
;
Humans
;
Thoracic Injuries*
;
Thorax*
;
Tomography, X-Ray Computed*
8.A case of reconstruction of facial asymmetry following Caldwell-Lucoperation.
Byung Cheol KIM ; In Gug NA ; Young Soo RHO ; Hyun Joon LIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(4):572-577
No abstract available.
Facial Asymmetry*
9.A clinical study of facial electroneuronography in normal persons.
Hyung Jong KIM ; In Gug NA ; Young Soo RHO ; Hyun Joon LIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(4):673-679
No abstract available.
Humans
10.A case of adenoid cystic carcinoma of the trachea.
Heon Ki MIN ; In Gug NA ; Young Soo RHO ; Hyun Joon LIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(1):162-167
No abstract available.
Adenoids*
;
Carcinoma, Adenoid Cystic*
;
Trachea*