1.Professional biobanking education in Korea based on ISO 20387
Jong Ok KIM ; Chungyeul KIM ; Sangyong SONG ; Eunah SHIN ; Ji-Sun SONG ; Mee Sook ROH ; Dong-chul KIM ; Han-Kyeom KIM ; Joon Mee KIM ; Yeong Jin CHOI
Journal of Pathology and Translational Medicine 2025;59(1):11-25
To ensure high-quality bioresources and standardize biobanks, there is an urgent need to develop and disseminate educational training programs in accordance with ISO 20387, which was developed in 2018. The standardization of biobank education programs is also required to train biobank experts. The subdivision of categories and levels of education is necessary for jobs such as operations manager (bank president), quality manager, practitioner, and administrator. Essential training includes programs tailored for beginner, intermediate, and advanced practitioners, along with customized training for operations managers. We reviewed and studied ways to develop an appropriate range of education and training opportunities for standard biobanking education and the training of experts based on KS J ISO 20387. We propose more systematic and professional biobanking training programs in accordance with ISO 20387, in addition to the certification programs of the National Biobank and the Korean Laboratory Accreditation System. We suggest various training programs appropriate to a student’s affiliation or work, such as university biobanking specialized education, short-term job training at unit biobanks, biobank research institute symposiums by the Korean Society of Pathologists, and education programs for biobankers and researchers. Through these various education programs, we expect that Korean biobanks will satisfy global standards, meet the needs of users and researchers, and contribute to the advancement of science.
2.Hepatic Kaposi Sarcoma after Kidney Transplantation:A Case Report
Seunghyeon ROH ; Myoung Seok LEE ; Siwon JANG ; Min Hoan MOON ; Joon Koo HAN
Journal of the Korean Society of Radiology 2025;86(1):141-147
Kaposi sarcoma is an undisputed malignancy associated with a heightened relative risk after transplantation. Similar to other causes of Kaposi’s sarcoma, cutaneous involvement is typical in post-transplant patients; however, visceral involvement rarely occurs. We report a rare case of de novo hepatic Kaposi’s sarcoma manifesting as an ill-defined infiltrative lesion in the left lobe of the liver in a patient who was immunosuppressed for 9 months after a kidney transplantation using ultrasonography, CT, MRI, and fluorodeoxyglucose-PET.
3.Professional biobanking education in Korea based on ISO 20387
Jong Ok KIM ; Chungyeul KIM ; Sangyong SONG ; Eunah SHIN ; Ji-Sun SONG ; Mee Sook ROH ; Dong-chul KIM ; Han-Kyeom KIM ; Joon Mee KIM ; Yeong Jin CHOI
Journal of Pathology and Translational Medicine 2025;59(1):11-25
To ensure high-quality bioresources and standardize biobanks, there is an urgent need to develop and disseminate educational training programs in accordance with ISO 20387, which was developed in 2018. The standardization of biobank education programs is also required to train biobank experts. The subdivision of categories and levels of education is necessary for jobs such as operations manager (bank president), quality manager, practitioner, and administrator. Essential training includes programs tailored for beginner, intermediate, and advanced practitioners, along with customized training for operations managers. We reviewed and studied ways to develop an appropriate range of education and training opportunities for standard biobanking education and the training of experts based on KS J ISO 20387. We propose more systematic and professional biobanking training programs in accordance with ISO 20387, in addition to the certification programs of the National Biobank and the Korean Laboratory Accreditation System. We suggest various training programs appropriate to a student’s affiliation or work, such as university biobanking specialized education, short-term job training at unit biobanks, biobank research institute symposiums by the Korean Society of Pathologists, and education programs for biobankers and researchers. Through these various education programs, we expect that Korean biobanks will satisfy global standards, meet the needs of users and researchers, and contribute to the advancement of science.
4.Hepatic Kaposi Sarcoma after Kidney Transplantation:A Case Report
Seunghyeon ROH ; Myoung Seok LEE ; Siwon JANG ; Min Hoan MOON ; Joon Koo HAN
Journal of the Korean Society of Radiology 2025;86(1):141-147
Kaposi sarcoma is an undisputed malignancy associated with a heightened relative risk after transplantation. Similar to other causes of Kaposi’s sarcoma, cutaneous involvement is typical in post-transplant patients; however, visceral involvement rarely occurs. We report a rare case of de novo hepatic Kaposi’s sarcoma manifesting as an ill-defined infiltrative lesion in the left lobe of the liver in a patient who was immunosuppressed for 9 months after a kidney transplantation using ultrasonography, CT, MRI, and fluorodeoxyglucose-PET.
5.Professional biobanking education in Korea based on ISO 20387
Jong Ok KIM ; Chungyeul KIM ; Sangyong SONG ; Eunah SHIN ; Ji-Sun SONG ; Mee Sook ROH ; Dong-chul KIM ; Han-Kyeom KIM ; Joon Mee KIM ; Yeong Jin CHOI
Journal of Pathology and Translational Medicine 2025;59(1):11-25
To ensure high-quality bioresources and standardize biobanks, there is an urgent need to develop and disseminate educational training programs in accordance with ISO 20387, which was developed in 2018. The standardization of biobank education programs is also required to train biobank experts. The subdivision of categories and levels of education is necessary for jobs such as operations manager (bank president), quality manager, practitioner, and administrator. Essential training includes programs tailored for beginner, intermediate, and advanced practitioners, along with customized training for operations managers. We reviewed and studied ways to develop an appropriate range of education and training opportunities for standard biobanking education and the training of experts based on KS J ISO 20387. We propose more systematic and professional biobanking training programs in accordance with ISO 20387, in addition to the certification programs of the National Biobank and the Korean Laboratory Accreditation System. We suggest various training programs appropriate to a student’s affiliation or work, such as university biobanking specialized education, short-term job training at unit biobanks, biobank research institute symposiums by the Korean Society of Pathologists, and education programs for biobankers and researchers. Through these various education programs, we expect that Korean biobanks will satisfy global standards, meet the needs of users and researchers, and contribute to the advancement of science.
6.Hepatic Kaposi Sarcoma after Kidney Transplantation:A Case Report
Seunghyeon ROH ; Myoung Seok LEE ; Siwon JANG ; Min Hoan MOON ; Joon Koo HAN
Journal of the Korean Society of Radiology 2025;86(1):141-147
Kaposi sarcoma is an undisputed malignancy associated with a heightened relative risk after transplantation. Similar to other causes of Kaposi’s sarcoma, cutaneous involvement is typical in post-transplant patients; however, visceral involvement rarely occurs. We report a rare case of de novo hepatic Kaposi’s sarcoma manifesting as an ill-defined infiltrative lesion in the left lobe of the liver in a patient who was immunosuppressed for 9 months after a kidney transplantation using ultrasonography, CT, MRI, and fluorodeoxyglucose-PET.
9.Machine Learning-Based Multi-Modal Prediction of Cognitive Decline in Community-Dwelling Older Adults
Jinhak KIM ; Narae KIM ; Bumhee PARK ; Hyun Woong ROH ; Chang Hyung HONG ; Sang Joon SON ;
Journal of Korean Geriatric Psychiatry 2024;28(2):33-40
Objective:
This study aimed to develop a machine learning model to predict cognitive decline in community-dwelling older adults. By integrating multimodal data, including demographic, psychosocial, and neuroimaging information, we sought to en-hance early detection of cognitive decline.
Methods:
Data were obtained from 159 participants in the Biobank Innovations for Chronic Cerebrovascular Disease with Alzheimer’s Disease Study. Participants underwent clinical assessments, neuropsychological testing, and magnetic resonance im-aging scans. Cognitive decline was defined as an increase in the Clinical Dementia Rating-Sum of Boxes of greater than 2.05 points per year at follow-up. Models were developed using the logistic classification, combining demographic, psychosocial as-sessments, and neuroimaging data. Model performance was evaluated using area under the curve (AUC), accuracy, and F1 score, while Shapley additive explanation values were used to assess feature importance.
Results:
The model that incorporated all data types achieved the highest performance, with an AUC of 0.834. The top predictor of cognitive decline was years of education, underscoring the importance of non-invasive, easily accessible data for prediction.
Conclusion
This machine learning model demonstrates significant potential for early cognitive decline prediction, offering a scalable tool for improving dementia screening and timely intervention, especially in resource-limited settings.
10.Machine Learning-Based Multi-Modal Prediction of Cognitive Decline in Community-Dwelling Older Adults
Jinhak KIM ; Narae KIM ; Bumhee PARK ; Hyun Woong ROH ; Chang Hyung HONG ; Sang Joon SON ;
Journal of Korean Geriatric Psychiatry 2024;28(2):33-40
Objective:
This study aimed to develop a machine learning model to predict cognitive decline in community-dwelling older adults. By integrating multimodal data, including demographic, psychosocial, and neuroimaging information, we sought to en-hance early detection of cognitive decline.
Methods:
Data were obtained from 159 participants in the Biobank Innovations for Chronic Cerebrovascular Disease with Alzheimer’s Disease Study. Participants underwent clinical assessments, neuropsychological testing, and magnetic resonance im-aging scans. Cognitive decline was defined as an increase in the Clinical Dementia Rating-Sum of Boxes of greater than 2.05 points per year at follow-up. Models were developed using the logistic classification, combining demographic, psychosocial as-sessments, and neuroimaging data. Model performance was evaluated using area under the curve (AUC), accuracy, and F1 score, while Shapley additive explanation values were used to assess feature importance.
Results:
The model that incorporated all data types achieved the highest performance, with an AUC of 0.834. The top predictor of cognitive decline was years of education, underscoring the importance of non-invasive, easily accessible data for prediction.
Conclusion
This machine learning model demonstrates significant potential for early cognitive decline prediction, offering a scalable tool for improving dementia screening and timely intervention, especially in resource-limited settings.

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