A 68-year-old female was referred to our ophthalmologic department due to pain, redness and decreased vision of the left eye. She had saddle nose deformity and erythematous swelling and deformity on right anricle. Both eyes represented recurring conjunctival injection and chemosis, episcleral injection, and anterior uveitis on follow-up examinations. Left eye showed proptosis and limitation of eyeball movement with acute increase of IOP. The fluorescein angiography showed the choroidal folds which were seen as alternating lines of hyper- and hypofluorescence. B-scan ultrasonograms showed thickening of posterior coats of eye and retrobulbar edema, which seemed to be critical in the diagnosis of the posterior scleritis.
Aged ; Choroid ; Congenital Abnormalities ; Diagnosis ; Edema ; Exophthalmos ; Female ; Fluorescein Angiography ; Follow-Up Studies ; Humans ; Nose ; Polychondritis, Relapsing* ; Scleritis* ; Ultrasonography ; Uveitis, Anterior

A 68-year-old female was referred to our ophthalmologic department due to pain, redness and decreased vision of the left eye. She had saddle nose deformity and erythematous swelling and deformity on right anricle. Both eyes represented recurring conjunctival injection and chemosis, episcleral injection, and anterior uveitis on follow-up examinations. Left eye showed proptosis and limitation of eyeball movement with acute increase of IOP. The fluorescein angiography showed the choroidal folds which were seen as alternating lines of hyper- and hypofluorescence. B-scan ultrasonograms showed thickening of posterior coats of eye and retrobulbar edema, which seemed to be critical in the diagnosis of the posterior scleritis.
Aged ; Choroid ; Congenital Abnormalities ; Diagnosis ; Edema ; Exophthalmos ; Female ; Fluorescein Angiography ; Follow-Up Studies ; Humans ; Nose ; Polychondritis, Relapsing* ; Scleritis* ; Ultrasonography ; Uveitis, Anterior

To examine prospectively the efficacy and reliability of excimer laser photorefractive keratectomy for myopia. we treated 147 eyes of 86 patients with a VisX Twenty/Twenty excimer laser and followed them up for 1 year and follow up 48 eyes of 26 patients for 2 years. The patients were divided into two groups with preoperative myopia: group 1 with diopters between -1.50 and -6.00, group 2 with diopters between -6.01 and -10.00. At 1 year, the group 1 with a mean preoperative refractive error of -4.61D changed to -0.40D, the group 2 changed from -7.50D to -0.92D. At 2 years, the group 1 with a mean preoperative refractive error of -4.28D changed to -0.41D, the group 2 changed from -7.75D to -1.04D. At 1 yera, in group 1, 90.91% (70 of 77) of eyes and in group 2, 64.29%(45 of 70) of eyes were corrected within 1D of intended refraction,respectively. At 1 years, in group 1, 94.81% (73 of 77) of eyes and in group 2, 84.29%(59 of 70) of eyes achieved an uncorrected visual acuity of 0.5 or better. And at 2 years, in group 1, 81.82% (18 of 22)of eyes, and in group 2, 50.00% (13 of 26) of eyes were corrected within 1D of intended refraction, respectively. At 2 years, in group 1, 95.50% (21% of 22) of eyes and in group 2, 84.62%(22 of 26) of eyes achieved an uncorrected visual acuity of 0.5 or better.
Follow-Up Studies* ; Humans ; Lasers, Excimer* ; Myopia* ; Photorefractive Keratectomy* ; Prospective Studies ; Refractive Errors ; Visual Acuity

This study was undertaken to localize fibronectin and type IV collagen in the cultured retinal pigment epithelial cell by means of immunofluorescent staining and immunocytochemical methods. Immunofluorescent staining and immunocytochemical methods revealed fibronectin and type IV collagen localized on the extracellular membrane of the cultured retinal pigment epithelial cell. Ultrastructural immunocytochemical technique also revealed fibronectin associated with extracellular tissue. This study demonstrated that fibronectin and type IV collagen are an integral component of the extracellular matrix of the human retinal pigment epithelial cell in vitro.
Cells, Cultured ; Collagen/*analysis ; Extracellular Matrix/*analysis/immunology ; Fibronectins/*analysis ; Fluorescent Antibody Technique ; Humans ; Immunohistochemistry ; Pigment Epithelium of Eye/*analysis

Visual field examination plays an important role in the diagnosis of ocular and neurological disorders. Visual field screening devices have become popular because they require less time than quantitative perimetry, are easier for both the patient and examiner to perform, and can be administered to a larger number of patients. However, these instruments are expensive and in need of specific equipment. To eliminate these disadvantages, Oculokinetic perimeter was designed by Bertil E. Damato. Oculokinetic perimetry can be performed with rapid and simple method and we examined the visual field by Oculokinetic perimeter and compared the results with those using the Goldmann perimeter and Autofield-D static perimeter.
Diagnosis ; Humans ; Mass Screening ; Nervous System Diseases ; Visual Field Tests* ; Visual Fields

The retinal and choroidal blood vessels respond independently to the abruptly increased arterial pressure due to their differences in the anatomic and physiologic properties, which induce hypertensive retinopathy and hypertensive choroidopathy respectively. The authors reviewed the fluorescein angiogram retrospectively to observe the ischemic changes of the choroid in 15 cases of hypertensive choroidopathy. The ischemic changes of the choroid in hypertensive choroidopathy were characterized by generalized or sectorial filling delay which was followed by staining or leakage of dye. These findings suggest that the choroidal circulation may lead to the sectorial and generalized ischemic conditions following the abruptly increased arterial pressure due to their differences in the anatomic structures. The fluorescein angiographic findings in the hypertensive choroidopathy depend on both the degree of the circulatory disturbance and the levels of the affected choroidal vessels.
Arterial Pressure ; Blood Vessels ; Choroid ; Fluorescein Angiography* ; Fluorescein* ; Hypertensive Retinopathy ; Retinaldehyde ; Retrospective Studies

The patients initially underwent epikeratoplasty for keratoconus but a penetrating kerato plasty was required due to the opacity in the cornea. By using of this specimen, which was obtained by trephination the healing process of the host-Ienticule cornea could be examined by electron microscopy and immunofluorescence method. Epithelial ingrowth over the lenticule was well formed by the regeneration of the basement membrane over the Bowman's membrane. However, the poor attachment of the lenticule over the host corneal stroma made the interface easily separated during the sectioning processes. Electron microscopic study revealed the keratocytes in the lenticule stroma vacuolized with large number of degenerated microorganelles. These results suggest that it may take a long time to complete the wound healing of the host-Ienticule interface despite the epithelial ingrowth onto the lenticule was well formed.
Basement Membrane ; Bowman Membrane ; Cornea ; Corneal Stroma ; Epikeratophakia* ; Extracellular Matrix ; Fluorescent Antibody Technique ; Humans ; Keratoconus ; Microscopy, Electron ; Regeneration ; Trephining ; Wound Healing

This study was undertaken in an attempt to localize fibronectin and collagen type IV to the cultured retinal pigment epithelial cell by means of immunofluorescent staining and immunocytochemrcal method. Immunofluorescent staining and immunocytochemical methcds revealed fibronectin and collagen type IV localized on the extracellular membrane of the cultured retinal pigment epithelial cell. Ultrastructural immunocytochemical technique also revealed fibronectin associated with extracellular tissue. This study demonstrated that fibronectin and collagen type IV are an integral component of the extracellular matrix of the retinal pigment epithelial cell in vitro.
Collagen Type IV ; Epithelial Cells* ; Extracellular Matrix* ; Fibronectins ; Membranes ; Retinaldehyde*

This study was performed to elucidate the cytologic characteristics of pseudomembrane, which was obtained from eight patients with epidemic keratoconjunctivltis. The predominant cells consisted of lymphocytes and degenerated epithelial cells with a few polymorphonuclear leukocytes and fibrin. Electron micrographs revealed the nuclear segregation, vermicellar body, viral microtubules, and intranuclear inclusion body. These findings suggest that the desquamated epithelial cell was infected by adenovirus.
Adenoviridae ; Epithelial Cells ; Fibrin ; Humans ; Intranuclear Inclusion Bodies ; Keratoconjunctivitis* ; Lymphocytes ; Microtubules ; Neutrophils

This study was performed to investigate the sequential changes of the retinal tissue in tissue culture condition. The human sensory retinal tissues were cultured for up to 2 weeks and 4 weeks, respectively. The initial changes showed the separation of the intercellular space and the consequent widening of the intercellular space with prolapse of cytoplasmic processes into the widened intercellular space. The internal limiting membrane was also separated from the inner retina, which led to the prolapse of the cytoplasm of the Muller cell. The growth of the Muller cell was most prominent during the 4-weeks' tissue culture period. These findings suggest that the Muller cell might contribute to the formation of cellular membrane in case of the defect of the internal limiting membrane in several pathologic conditions.
Adult ; Cell Membrane/ultrastructure ; Cells, Cultured ; Humans ; Male ; Middle Aged ; Neuroglia/*ultrastructure ; Retina/*ultrastructure