No abstract available.
Muscle, Skeletal* ; Tibial Nerve*

Purpose: As women in middle age undergo the menopausal transition, they may encounter alterations in sexual function concomitantly with physical and emotional manifestations. The present research investigated the relationships between menopausal symptoms, depression, marital intimacy, and sexual function. Additionally, it aimed to identify the mediating influences of depression and marital intimacy in the relationship between menopausal symptoms and sexual function in naturally post-menopausal women with hypertension. Methods: The study included post-menopausal women aged between 45 and 60 years with hypertension who were not undergoing hormone replacement therapy. A total of 308 post-menopausal women were recruited from three provinces in Korea. Path analysis was conducted by AMOS employing maximum likelihood estimation and bootstrapping with 2000 samples. Results: The theoretical pathway model demonstrated strong alignment with empirical findings obtained from a cohort of postmenopausal women. The association between menopausal symptoms and sexual function was mediated by depression and marital intimacy. Ultimately, menopausal symptoms, depression, and marital intimacy collectively explained 64% of the overall variance in sexual function. Conclusion This study highlights the importance of individualized interventions targeting sexual health in middle-aged women with hypertension undergoing menopause. Counseling and intervention programs focused on alleviating menopausal symptoms and improving sexual function should be integrated into clinical practice. Furthermore, a multidimensional approach is needed to address the various factors influencing sexual function in postmenopausal women.

Purpose: As women in middle age undergo the menopausal transition, they may encounter alterations in sexual function concomitantly with physical and emotional manifestations. The present research investigated the relationships between menopausal symptoms, depression, marital intimacy, and sexual function. Additionally, it aimed to identify the mediating influences of depression and marital intimacy in the relationship between menopausal symptoms and sexual function in naturally post-menopausal women with hypertension. Methods: The study included post-menopausal women aged between 45 and 60 years with hypertension who were not undergoing hormone replacement therapy. A total of 308 post-menopausal women were recruited from three provinces in Korea. Path analysis was conducted by AMOS employing maximum likelihood estimation and bootstrapping with 2000 samples. Results: The theoretical pathway model demonstrated strong alignment with empirical findings obtained from a cohort of postmenopausal women. The association between menopausal symptoms and sexual function was mediated by depression and marital intimacy. Ultimately, menopausal symptoms, depression, and marital intimacy collectively explained 64% of the overall variance in sexual function. Conclusion This study highlights the importance of individualized interventions targeting sexual health in middle-aged women with hypertension undergoing menopause. Counseling and intervention programs focused on alleviating menopausal symptoms and improving sexual function should be integrated into clinical practice. Furthermore, a multidimensional approach is needed to address the various factors influencing sexual function in postmenopausal women.

Purpose: As women in middle age undergo the menopausal transition, they may encounter alterations in sexual function concomitantly with physical and emotional manifestations. The present research investigated the relationships between menopausal symptoms, depression, marital intimacy, and sexual function. Additionally, it aimed to identify the mediating influences of depression and marital intimacy in the relationship between menopausal symptoms and sexual function in naturally post-menopausal women with hypertension. Methods: The study included post-menopausal women aged between 45 and 60 years with hypertension who were not undergoing hormone replacement therapy. A total of 308 post-menopausal women were recruited from three provinces in Korea. Path analysis was conducted by AMOS employing maximum likelihood estimation and bootstrapping with 2000 samples. Results: The theoretical pathway model demonstrated strong alignment with empirical findings obtained from a cohort of postmenopausal women. The association between menopausal symptoms and sexual function was mediated by depression and marital intimacy. Ultimately, menopausal symptoms, depression, and marital intimacy collectively explained 64% of the overall variance in sexual function. Conclusion This study highlights the importance of individualized interventions targeting sexual health in middle-aged women with hypertension undergoing menopause. Counseling and intervention programs focused on alleviating menopausal symptoms and improving sexual function should be integrated into clinical practice. Furthermore, a multidimensional approach is needed to address the various factors influencing sexual function in postmenopausal women.

The aim of present study was to evaluate the influence of periodontal status of adjacent tooth and loading time to the prevalence of red complex of implant sulcus. In 97 patients, partially edentulous subjects with endosseous root-form implants were selected. All subjects were medically healthy and had not taken systemic antibiotics and professional plaque control 3 months before sampling. The number was as follows: clinically healthy implants:161, clinically unhealthy implants:22, clinically healthy adjacent teeth:73, clinically unhealthy adjacent teeth:38. All teeth and implants of each patient were examined probing depth(PD), modified sulcus bleeding index(mSBI), and modified plaque index(mPI), and samples of subgingival plaque were obtained at each site with sterile curet or fine paper points, then the plaque transferred to PBS. Obtained samples were examined for the presence of P. gingivalis, T. forsythensis, and T. denticola by the polymerase chain reaction (PCR). The relationship among clinical parameters and the colonizations by the 3 bacterial species from adjacent teeth and implants region were analyzed by student t-test (p<0.05). The results of this study were as follows: 1. mPI and mSBI of implant increased with increasing of same indices of adjacent tooth(p=0.03,0.001), but not in the PD . 2. The mPI, mBI, PD of implants was higher when red complex exist. 3. The prevalence of red complex was higher when the periodontal condition is unhealthy. 4. The prevalence of red complex of implants has no significant relation to the probing depth of adjacent tooth. 5. Prevalence of P. gingivalis, T. forsythensis of implants increased with loading time. (p=0.02,0.018) These results shows the importance of oral hygiene and supportive periodontal therapy.
Anti-Bacterial Agents ; Colon ; Hemorrhage ; Humans ; Oral Hygiene ; Polymerase Chain Reaction ; Prevalence ; Tooth

BACKGROUND/AIMS: To review the cases of surgically-treated intrahepatic cholangiocarcinoma, and to evaluate the clinical and pathologic features of intrahepatic cholangiocarcinoma that may affect longterm survival among Korean patients. MATERIALS AND METHODS: From 1990 to 1997, 28 patients with intrahepatic cholangiocarcinoma underwent laparotomy. Among them, resection was performed in 25 patients and wedge resection in only 3 patients. The liver resections included: 5 right lobectomies, 1 right trisegmentectomy, 7 left lobectomies, 3 extended left lobectomies, 2 hepatopancreatoduodenectomies and 7 segmentectomies. Curative resection was performed on 15 patients. The histological sections of all resected specimens were immunohistochemically stained with p53 and Ki-67 monoclonal antibodies to assess biological behavior of the tumor cells. The cumulative survival rate and clinicopathological factors, including biological markers (p53, Ki-67), that may influence prognosis were analyzed stastistically. RESULTS: The patients undergoing curative resection survived significantly longer than the patients undergoing noncurative resection. The median survival time for patients with curative resection was 24 months (mean, 34+/-8 months) with 1-, 2-, and 3-year survival rates of 66.6%, 44.4%, and 35.6%, respectively. The median survival time for patients with noncurative resection was 3 months (mean, 8+/-3 months) with 1- and 2-year survival rates of 26.7% and 13.4%, respectively. Univariate analysis showed that positive regional lymph node significantly correlated with poor prognosis (p=0.004); and that curative resection significantly correlated with better prognosis (p=0.001). Age, sex, tumor size, the degree of cell differentiation, gross type of tumor, and p53 and Ki-67 labeling index had no significant correlation with prognosis. CONCLUSION: Our results support the idea that an aggressive liver resection along with regional lymph node dissection is recommended for long-term survival. The validity of the molecular biologic tumor markers (p53, Ki -67) as a prognostic factor is not yet clearly defined.
Antibodies, Monoclonal ; Biomarkers ; Cell Differentiation ; Cholangiocarcinoma* ; Fibrinogen ; Hepatectomy ; Humans ; Laparotomy ; Liver ; Lymph Node Excision ; Lymph Nodes ; Mastectomy, Segmental ; Prognosis ; Survival Rate ; Biomarkers, Tumor

Odontogenic keratocysts are benign intraosseous tumors of odontogenic origin that occur most commonly in the jaw. In particular, they have a predilection for the angle and ascending ramus of the mandible. In contrast, odontogenic keratocysts arising in the maxillary sinus are relatively rare. Two such cases are reported herein. In addition, the English literature that concerns odontogenic keratocysts of the maxillary sinus is reviewed.
Jaw ; Mandible ; Maxillary Sinus ; Odontogenic Cysts ; Tooth

BACKGROUND: Bipolar hemiarthroplasty for unstable intertrochanteric fractures in elderly patients is a viable option that can prevent the complications of an open reduction, such as nonunion and metal failure. This study evaluated the clinicoradiological results of cementless bipolar hemiarthroplasty for unstable intertrochanteric fractures in elderly patients. METHODS: Forty hips were followed for more than 2 years after cementless bipolar hemiarthroplasty using a Porocoat(R) AML Hip System. The mean age was 78.8 years and the mean follow-up period was 40.5 months. The Harris hip score and postoperative hip pain were analyzed clinically. The radiological results were assessed using a range of indices. RESULTS: At the last follow-up, the mean Harris hip score was 80.6 points. There were one case of hip pain and one case of thigh pain. Twenty-four cases (60%) showed no decrease in ambulation capacity postoperatively. Radiologically, there were 23 cases (57.5%) of fixation by bone ingrowth and 17 cases (42.5%) of stable fibrous fixation. There were no cases of osteolysis. Eleven cases (27.5%) of new bone formation were found around the stem. All stems were stable without significant changes in alignment or progressive subsidence. CONCLUSIONS: The short-term results of cementless bipolar hemiarthroplasty in elderly patients with unstable intertrochanteric fractures were satisfactory.
Activities of Daily Living ; Aged ; *Arthroplasty, Replacement, Hip ; Female ; Hip/radiography ; Hip Fractures/radiography/*surgery ; *Hip Prosthesis ; Humans ; Male ; Pain Measurement ; Postoperative Care ; *Prosthesis Design ; Walking

BACKGROUND AND PURPOSE: Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most-common single gene disorder of cerebral small vessel disease. There is no definite evidence of genotype-phenotype correlation in CADASIL. However, recent studies have shown the unique phenotypic feature of NOTCH3 R544C mutation. METHODS: We investigated the phenotypic spectrum of NOTCH3 R544C mutation in 73 CADASIL patients in Jeju between April 2012 and January 2014. RESULTS: Of the 73 subjects from 60 unrelated families included in this study, 40 (55%) were men. The mean age of the subjects was 62.2±12.2 (range 34-86 years). Cerebral infarction was the most frequent manifestation (37%), followed by cognitive impairment (32%), headache (17%), psychiatric symptom (16%), intracerebral hemorrhage (12%), transient ischemic attack (7%), and seizure (1%). The mean age of the subjects with ischemic or hemorrhagic episodes was 64.9±10.9 (range 41-86 years). A diagnosis of dementia was made in 12 subjects (16%). The mean age of the subjects with dementia was 75.6±6.5 (range 62-86 years). About 3% of subjects were unable to walk without assistance at assessment. Only one subject had developed chronic headache before the 40s. CONCLUSIONS: Our data support the hypothesis that CADASIL patients with R544C mutation in Jeju have relatively late onset disease.
CADASIL ; Cerebral Hemorrhage ; Cerebral Infarction ; Cerebral Small Vessel Diseases ; Dementia ; Diagnosis ; Genetic Association Studies ; Genotype ; Headache ; Headache Disorders ; Humans ; Ischemic Attack, Transient ; Leukoencephalopathies* ; Male ; Phenotype ; Seizures

No abstract available.
Hyaluronic Acid*