1.Association with Autoimmune Disease in Patients with Premature Ovarian Failure.
Joon Cheol PARK ; Jong In KIM ; Jeong Ho RHEE
Korean Journal of Fertility and Sterility 2004;31(3):149-154
OBJECTIVE: To assess the association with autoimmune endocrine diseases and detection rate of autoimmune antibodies and its clinical significance in patients with premature ovarian failure. METHODS: Twenty eight patients with primary or secondary amenorrhea manifesting hormonal and clinical features of premature ovarian failure (primary POF: 7, secondary POF: 21) were investigated. We tested them TFT, 75 g OGTT, ACTH and S-cortisol for thyroiditis, IDDM, Addison's disease, and antithyoglobulin antibody, antimicrosomal antibody, antinuclear antibody, rheumatic factor, anti-smooth muscle antibody, anti-acetylcholine receptor antibody for non-organ specific autoimmune disorders. RESULTS: Only one patient was diagnosed as IDDM and no patients had abnormal TFT or adrenal function test. More than one kind of autoantibody was detected in 11 patients of all (39.2%): 5 patients (71.4%) of primary POF group and 6 patients (21.4%) of secondary POF group. Eleven patients (39.3%) had antithyroglobulin antibody, 4 (14.3%) had antimicrosomal antibody, 2 (7.1%) had antinuclear antibody, 2 (7.1%) had rheumatic factor, 1 (3.6%) had anti-smooth muscle antibody, 1 (3.6%) had anti-acetylcholine receptor antibody. CONCLUSIONS: Premature ovarian failure may occur as a component of an autoimmune polyglandular syndrome, so patients should be measured with free thyroxine, thyroid-stimulating hormone, fasting glucose and electrolytes. Measurement of thyroid autoantibodies in POF patients may be important in identifying patients at risk of developing overt hypothyoidism, but other autoantibodies may not be suitable for screening test.
Addison Disease
;
Adrenocorticotropic Hormone
;
Amenorrhea
;
Antibodies
;
Antibodies, Antinuclear
;
Autoantibodies
;
Autoimmune Diseases*
;
Diabetes Mellitus, Type 1
;
Electrolytes
;
Endocrine System Diseases
;
Fasting
;
Female
;
Glucose
;
Glucose Tolerance Test
;
Humans
;
Mass Screening
;
Primary Ovarian Insufficiency*
;
Thyroid Gland
;
Thyroiditis
;
Thyrotropin
;
Thyroxine
2.A Case of Livebirth by Delayed Interval Delivery in Twin Pregnancy.
Yong Joon JEON ; Jong In KIM ; Jeong Ho RHEE
Korean Journal of Perinatology 2001;12(2):168-172
No abstract available.
Humans
;
Pregnancy, Twin*
3.The Relation of Antipsychotic Drug Induced-Acute Dystonia and Serum Iron Level.
Dong Jin LEE ; In Joon PARK ; Young Joon KWON ; Hee Yeon JEONG ; Sun Ho HAN
Journal of the Korean Society of Biological Psychiatry 1998;5(2):248-252
OBJECT: This study was performed in order to examine the correlation between acute neuroleptic-induced dystonic reactions and serum iron level. METHOD: Serum iron levels were measured in psychiatric inpatients who had developed acute neuroleptic-induced dystonia(N=41) and in control patients with no history of acute dystonic reactions(N=37). Serum iron levels were compared in acute dystonic inpatients before starting treatment with neuroleptics and after acute dystonic reaction. RESULTS: The patients exhibiting acute dystonic reactions had significantly lower serum iron levels than the patients without acute dystonic reactions. CONCLUSION: This result supports an association between low serum iron and the occurrence of neuroleptic-induced acute dystonic reactions.
Antipsychotic Agents
;
Dystonia*
;
Humans
;
Inpatients
;
Iron*
4.Comparison of postoperative pulmonary complications between sugammadex and neostigmine in lung cancer patients undergoing video-assisted thoracoscopic lobectomy: a prospective double-blinded randomized trial
Tae Young LEE ; Seong Yeop JEONG ; Joon Ho JEONG ; Jeong Ho KIM ; So Ron CHOI
Anesthesia and Pain Medicine 2021;16(1):60-67
Background:
Reversal of neuromuscular blockade (NMB) at the end of surgery is important for reducing postoperative residual NMB; this is associated with an increased risk of postoperative pulmonary complications (PPCs). Moreover, PPCs are associated with poor prognosis after video-assisted thoracoscopic surgery (VATS) for lobectomy. We compared the effects of two reversal agents, sugammadex and neostigmine, on the incidence of PPCs and duration of hospital stay in patients undergoing VATS lobectomy.
Methods:
After VATS lobectomy was completed under neuromuscular monitoring, the sugammadex group (n = 46) received sugammadex 2 mg/kg, while the neostigmine group (n = 47) received neostigmine 0.05 mg/kg with atropine 0.02 mg/kg after at least the third twitch in response to the train of four stimulation. The primary outcome was incidence of PPCs. The secondary outcomes were duration of hospital stay and intensive care unit (ICU) admission.
Results:
There was no significant difference in the incidence of PPCs for both the sugammadex and neostigmine groups (32.6% and 40.4%, respectively; risk difference = 0.08; 95% confidence interval = [−0.12, 0.27]; P = 0.434). The lengths of hospital (P = 0.431) and ICU (P = 0.964) stays were not significantly different between the two groups.
Conclusions
The clinical use of sugammadex and neostigmine in NMB reversal for patients undergoing VATS lobectomy was not significantly different in the incidence of PPCs and duration of hospital and ICU stay.
5.Intraosseous Lipoma A report of four cases.
Hye Jeong CHOI ; Mi Jin GU ; Joon Hyuk CHOI ; Duk Seop SHIN ; Kil Ho CHO
Korean Journal of Pathology 1999;33(6):467-470
Intraosseous lipoma is a very rare primary tumor of the bone. We report four cases of intraosseous lipoma. The patient ranged in age from 34 to 59-year-old (median age: 35 year-old). There were three men and one woman. All of four cases presented with pain. The involved bones were calcaneus in two cases, tibia in one case and ilium in one case, respectively. In all cases plain x-ray film revealed well-defined lytic lesion. Their size ranged 2 to 4.5 cm (mean size: 3.5 cm). Histologic examination showed mature adipose tissue. Three cases showed secondary changes such as atrophic bone, fat necrosis, fibrosis, dystrophic calcification, and reactive ischemic bone formation. The clinicopathologic and roentgenographic correlation are necessary in establishing correct diagnosis of this tumor.
Adipose Tissue
;
Calcaneus
;
Diagnosis
;
Fat Necrosis
;
Female
;
Fibrosis
;
Humans
;
Ilium
;
Lipoma*
;
Male
;
Middle Aged
;
Osteogenesis
;
Tibia
;
X-Ray Film
6.A Case of Type III Hyperlipoproteinemia Associate with Xanthoma Tuberosum and Xanthoma Striatum Palmare.
Nam Joon CHO ; Wook LEW ; Jeong Ho KIM ; Seung Hun LEE
Korean Journal of Dermatology 1994;32(2):321-326
We report a case of type III hyperlipoproteinemia associated with xanthoma eruptivum. Xanthoma tuberosum, and xanthoma striatum palmare whose clinical symptoms have been improved by the treatment of gemfibrozil. A 31-year-old male patient visited our clinic for evaluation of multiple yellowish nodules on the elbows, multiple yellowish plaques on the buttocks and linear yellowish plaques along with the palmar creases on both palms. The blood chemistry showed an elevation of cholesterol and triglyceride. Lipoprotein electrophoresis showed broad betazone and plasma standing test showed turbid plasma. Lipoprotein ultracentrifugation showed that the ratio of VLDL cholesterol and plasma triglyceride was 0.38. According to the above findings, we diagnosed this patient as type III hyperlipoproteinemia. After 4 months of treatment with diet and gemfibrozil, the serum level of cholesterol and triglyceride were reduced to normal range. The skin lesions of both palms showed marked improvement but the skin lesions on elbows and buttocks were not much improved.
Adult
;
Buttocks
;
Chemistry
;
Cholesterol
;
Cholesterol, VLDL
;
Diet
;
Elbow
;
Electrophoresis
;
Gemfibrozil
;
Humans
;
Hyperlipoproteinemia Type III*
;
Lipoproteins
;
Male
;
Plasma
;
Reference Values
;
Skin
;
Triglycerides
;
Ultracentrifugation
;
Xanthomatosis*
7.Correlation of plain film and computed tomography findings of lobar atelectasis.
Ho Joon KIM ; Jeong Mi KWEON ; Yeon Won PARK ; Byung Hee CHUN ; Young Duk JOH
Journal of the Korean Radiological Society 1991;27(2):245-251
No abstract available.
Pulmonary Atelectasis*
8.Esophageal complex reconstruction for corrosive esophagitis complicated with gastric outlet obstruction:2 case.
Jeong Soo KIM ; Keun Ho LEE ; Chang Joon AHN ; Rae Sung KANG
Journal of the Korean Surgical Society 1993;44(2):294-300
No abstract available.
Esophagitis*
9.Ketamine Use of Pediatric Sedation in Emergency Room.
Jeong Pill SEO ; Jun Seok PARK ; Tae Sik HWANG ; Seok Joon JANG ; Seung Ho KIM
Journal of the Korean Society of Emergency Medicine 2000;11(3):339-344
BACKGROUND: Ketamine use in emergency room has been increased. It has rapid onset of action and appropriate duration of action. It does not need endotracheal intubation and produces potent analgesia, sedation, and amnesia. The object of this study is to determine the safety and the degree of physician's satisfaction in relation to ketamine use. MATERIALS AND METHODS: This is a prospective study using protocol. Pediatric trauma patients who need sedation were given IM ketamine(4mg/kg) and atropine(0.01mg/kg) in a same syringe. Monitoring of patients was done by EM residents and complications of ketamine use were recorded. Physician's satisfaction was also recorded after the procedure. RESULTS: Intramuscular ketamine was administered 54 times, mainly for laceration repair. Physicians completed protocol for 51 of treated children. The median time for onset of sedation was 6.5+/-2.4 min, and duration of action was 32.4+/-10.8 min. Hypersalivation occurred in 9.8%(n=5); random movement 3.9%(n=2), emesis during procedure(n=1), emesis at home(n=1), and transient oxygen desaturation(n=1). All were quickly identified and treated without specific airway management and sequelae. Of 84% of physicians was satisfied with ketamine use for pediatric sedation. CONCLUSION: Intramuscular ketamine can be administered safely and satisfactorily in emergency room to facilitate pediatric procedures in conjunction with a defined protocol and appropriate monitoring.
Airway Management
;
Amnesia
;
Analgesia
;
Child
;
Emergencies*
;
Emergency Service, Hospital*
;
Humans
;
Intubation, Intratracheal
;
Ketamine*
;
Lacerations
;
Oxygen
;
Prospective Studies
;
Sialorrhea
;
Syringes
;
Vomiting
10.Surgical Complications in 250 Renal Transplants: Clinical Course and Outcome.
Kwi Ho PARK ; Joon Heon JEONG ; Jin Min KONG
The Journal of the Korean Society for Transplantation 1998;12(2):199-208
The surgical technique of renal transplantation has been well established, but surgical complications are not uncommon and still be important factors in postoperative mortality and morbidity. From August 1990 to May 1998, we performed 250 consecutive renal transplantations at Maryknoll hospital. The authors analyzed the kinds and incidences of surgical complications in a single center by using information from hospital records. The results were as follows: 1. The overall surgical complication rate was 9.6% (24 episodes in 250 cases). 2. These were composed of 6 vascular, 8 urologic, 4 lymphatic, and 6 wound complications. 3. Vascular complication included renal artery stenosis in 1 case and bleeding and hematoma in 5 cases. 4. Urologic complication included urine leakage in 4 cases, ureter stenosis in 2 cases and bladder stone in 2 cases. 5. Lymphatic complication was all lymphoceles. 6. One case in which renal artery stenosis had occured progressed to graft loss after 4 years later. There was no complication related mortality. 7. 1 year, 3 year and 5 year graft survival rate was 97.2%, 94.8% and 90.0%, respectively. and patient survival rate was 98.0%, 95.6% and 94.7%, respectively.
Constriction, Pathologic
;
Graft Survival
;
Hematoma
;
Hemorrhage
;
Hospital Records
;
Humans
;
Incidence
;
Kidney Transplantation
;
Lymphocele
;
Mortality
;
Renal Artery Obstruction
;
Survival Rate
;
Transplants
;
Ureter
;
Urinary Bladder Calculi
;
Wounds and Injuries