1.MR imaging of oral cavity malignancy.
Dong Gyu NA ; Moon Hee HAN ; Sang Joon KIM ; Kwang Hyun KIM ; Kee Hyun CHANG
Journal of the Korean Radiological Society 1993;29(2):179-185
We retrospectively analyzed the Magnetic Resonance (MR) imaging findings in 41 cases of histologically proved malignant tumors of oral cariey. The diagnostic value of MR imaging in detection and delineation of the lesions was assessed. The value of MRI was compared with that of Computed Tomography (CT) in 14 patients. Thirty-four cases of 41 malignant tumors were squamous cell carcinomas. Adenoic cystic carcinomas (2 cases), malignant melanomas (2 cases), non-Hodgkin lymphomas (2 cases) and mucoepidermoid carcinoma(1 cases) were also included in this study. Most of the lesions were isointense or slightly hyperintense to muscle on T1 weighted images and showed variable degrees of high signal intensity on T2 weighted images. Two cases of malignant melanomas showed characteristic hyperintensity on T1 weighted images. T2 weighted image was better in detection and delineation of tumor in most of the cases. In 6 cases, Gd-DTPA-enhanced T1 weighted image was better than T2 weighted image. T2 weighted image was useful for the evaluation of deep tissue infiltration and T1 weighted image was useful for the evaluation of bone invasion and superficial tissue plane invasion. The lesion was detected only by MR in 3 cases of 14 in which CT was also performed. MR imaging was more sensitive in the evalustion of bone marrow involvement. MR imaging is very useful modality in evaluating oral cavity malignany and is superior to CT in delineation of the as well as in the evaluation of mandible invasion.
Bone Marrow
;
Carcinoma, Squamous Cell
;
Humans
;
Lymphoma, Non-Hodgkin
;
Magnetic Resonance Imaging*
;
Mandible
;
Melanoma
;
Mouth*
;
Retrospective Studies
2.The Significance of Teardrop Changes in Developmental Dislocation of the Hip.
Seok Hyun LEE ; Won Young SHON ; Hyeon Il JEOUNG ; Joon Gyu MOON ; Ki Seong KIM
The Journal of the Korean Orthopaedic Association 1998;33(2):319-325
Prediction of acetabular development after reduction in treatment of developmental dysplasia of thc hip (DDH) is earlier, the hetter results because it would help ensure optimal timing of additional procedure if necessary. In this respect, authors reviewed retrospectively the radiographs of the hips of 35 children with DDH who had unilateral involvement and treated hy senior author (S.H.Lee) from the heginning with single successful attempt of reduction. The radiographs which were made at the time of initial diagnosis, one, two year nfter reduction und final follow up were assessed of teardrop figures. The results of treatment were classified as satisfactory group(CE > 10degrees ) and unsatisfactory group(CE < 10degrees) judged hy center-edge angle(CE degrees) at final follow-ups. 1. The teardrop figures were classifiable into 4 distinct groups as i)absent. ii)V-shaped, iii)Ushaped, iv) inverted D-shaped. 2. The teardrop figures in normal sides of hip were all U-shaped. 3. In dislocated but with satisfactory result group(24 cases), absent at 2 cases(8%), U-shaped teardrop was seen at 13 cases(54%), V-shaped in 9 cases(38%), and inverted 2-shaped in 0 case at I year after reduction. 4. In dislocated but with unsatisfactory result group( 11 cases), they were mostly of V-shaped(7 cases, 64%). The rest were of ahsent in 4 cases(36%) . hut none of U-shaped and inverted 2-shaped. In conclusions, teardrop figures appeared as significant predictor of future development of hip joint. Teardrop figure which stay as V-shaped at one year after reduction seems suggestive of insufficient reduction of DDH, therehy calls for early additional procedure.
Acetabulum
;
Child
;
Diagnosis
;
Dislocations*
;
Dronabinol
;
Follow-Up Studies
;
Hip Joint
;
Hip*
;
Humans
;
Retrospective Studies
3.Clinical study of the placenta previa.
Mi Jung LEE ; Kyung Ik KWON ; Joon Hyung JOE ; Joong Gyu PARK ; Won Joo LEE ; Nam Gyu JOE ; Jong In KIM ; Tack Hoon KIM
Korean Journal of Obstetrics and Gynecology 1993;36(12):3890-3896
No abstract available.
Placenta Previa*
;
Placenta*
4.Etoposide, adriamycin, cisplatin(EAP) combination chemotherapy for advanced gastric cancer.
Joon Sik KIM ; Jeong Hee KIM ; Own Gyu UH ; Si Young KIM ; Hwi Joong YOON ; Kyung Sam CHO
Journal of the Korean Cancer Association 1992;24(4):562-569
No abstract available.
Doxorubicin*
;
Drug Therapy, Combination*
;
Etoposide*
;
Stomach Neoplasms*
5.Selective Neurotomy of Sacral Lateral Branches for Pain of Sacroiliac Joint Dysfunction.
Hyo Joon KIM ; Dong Gyu SHIN ; Hyoung Ihl KIM ; Dong A SHIN
Journal of Korean Neurosurgical Society 2005;38(5):338-343
OBJECTIVE: The sacroiliac joint complex is often related with functionally incapacitating pain in old aged people. The purpose of this study is to delineate the investigation strategies and to determine the long-term effect of radiofrequency (RF) neurotomies for pain arising from sacroiliac joint dysfunction(SIJD) METHODS: Sixteen patients were diagnosed as having chronic pain from SIJD by comparative controlled blocks on L5 dorsal rami, sacroiliac joints and deep interosseous ligaments. After confirming the positive response (more than 50% of pain relief), sensory stimulation was applied to detect the `pathological' branches. Subsequently, RF neurotomies were performed on the selected nerve branches. Surgical outcome was graded as successful, moderate improvement, and failure after a 6month follow-up period. RESULTS: Stimulation intensity was 0.45V to elicit pain response in the L5 dorsal rami and lateral sacral branches. The number of RF-lesioned nerve branches was 6per patient. The average number of lesions for each branch was 1.3. Most commonly selected branches were L5 dorsal ramus (88%) and S2-upper division (88%). Ten patients (63%) reported a successful outcome according to the outcome criteria after 6months of follow-up, and five patients (31%) reported complete relief (100%). Five patients (31%) showed moderate improvements. One patient reported failure. CONCLUSION: RF neurotomy of lateral sacral branches is an excellent treatment modality for the pain due to SIJD, provided that comparative controlled block shows a positive response.
Chronic Pain
;
Follow-Up Studies
;
Humans
;
Ligaments
;
Sacroiliac Joint*
6.Clinical Value of Preoperative CA-125 Assay in Patients with Ovarian Mass.
Gi Youn HONG ; Young Gyu LEE ; Seung Joon LEE ; Heung Gon KIM ; Bu Kie MIN ; Kie Suk KIM
Korean Journal of Gynecologic Oncology and Colposcopy 1995;6(2):62-68
This study was undertaker to define the usefuness of preoperative CA-125 assay as a diagnostic bmor marker in differentiating malignancy from benign ovarian mass. Senun CA-125 were imneasured by Microparticle Enzyme Immunoassay(MEIA) in 94 patients with ovarian mass. The results were of follows ; 1. The mean value of preopentive senun CA-125 was 18.40u/ml in benign ovarian mass and 225.99u/ml in malignant ovarian mass (P<0.001). 2. The positive rete of Ca-125 in benign ovarian mass was 10%, compared 80% in malignant ovarian mass. 3. In analysis of histolovgic type, posisitive rate of serum CA-125 in malignant serous tumor was 82%, cornpared 50% in malignant mucinoins tumor. 2. No statistically significant correlation was observed between CA-125 value and patient's age. 5. The sensitivitiy, specifieity, positive predictive value & negative predictive value were 80%, 90%, 60% & 96%, respectively in cut off value, 35u/ml, And increasing cut off value 65u/ml, sensitivity, specificity, positive predictive value & negative predictive value were 40%, 96%, 67%, 90%, resqxetively. These data suggest the preperative serum CA-125 level correlate with maignant stattis in ovarian mass. And cut off value 35u/ml was better than 65u/ml in screening for ovarian cancer.
Humans
;
Mass Screening
;
Ovarian Neoplasms
;
Sensitivity and Specificity
7.Effect of the Type of Computer on Computerized Neurobehavioral Performance Tests.
Gyu Tae KIM ; Chang Yoon KIM ; Joon SAKONG
Korean Journal of Occupational and Environmental Medicine 2004;16(3):276-286
OBJECTIVES: It is difficult to carry and set up a large numbers of computers when computerized neurobehavioral tests are performed to many subjects. There are difficulties in mobilizing and resetting desktop computers and so, the use of desktop computers will decrease due to the recent increasing popularity of laptop computers. However, it is essential that there is no difference between the tests performed on a laptop and on a desktop computer. This study was conducted to estimate the effect that the type of computer has on computerized neurobehavioral performance tests. METHODS: Three types of computers were applied. Type 1 was a normal laptop computer. Type 2 was a laptop computer that was remodeled and equipped with a modified keyboard. A common desktop computer with a remodeled keyboard as type 3. The computerized tests included Simple Reaction Time, Choice Reaction Time, Symbol Digit, and Finger Tapping Speed. A total of 60 subjects were examined by the identical tester in the same testing conditions. The computers were randomly allocated, which were used in the test and let examinees take tests with the separate computers. RESULTS: There were no significant differences among the computers for the results of the Simple Reaction Time and Finger Tapping Speed tests. The mean reaction time, error number of Choice Reaction Time and mean reaction time, correct mean reaction time, error number of Symbol Digit produced significantly different results among the three types of computers. CONCLUSION: This study indicates that with only a laptop computer the Simple Reaction Time test using the space bar was useful. But with the laptop computer, the Choice Reaction Time test using the four-direction key and the Symbol Digit test using the upper end number key were unsuitable. The keyboard should be developed further for the Choice Reaction Time and Symbol Digit tests. Among the three computers, we recommend the use of the desktop computer with the remodeled keyboard which the examinees are familiar with and the laptop computer with the remodeled keyboard.
Fingers
;
Linear Energy Transfer
;
Reaction Time
8.A Case of Intrinsic Spinal Cord Lesions Complicating Epidural Anesthesia.
Joon Sung AHN ; Sang Jin KIM ; Eung Gyu KIM
Journal of the Korean Neurological Association 2006;24(2):181-183
No abstract available.
Anesthesia, Epidural*
;
Spinal Cord*
9.Role of Percutaneous Pleural Needle Biopsy in the Diagnosis of Lymphocyte Dominant Pleural Effusion.
Jae Joon YIM ; Woo Jin KIM ; Chul Gyu YOO ; Young Whan KIM ; Sung Koo HAN ; Young Soo SHIM
Tuberculosis and Respiratory Diseases 1997;44(4):899-906
BACKGROUND: The percutaneous pleural needle biopsy have been regarded as cornerstone in the diagnosis of lymphocyte dominant pleural effusions of which acid fast bacilli smear and cytologic exam was negative. However, the complications of percutaneous pleural needle biopsy is not rare arid its diagnostic efficacy is not always satisfactory. Recently, pleural fluid adenosine deaminase (ADA) and carcinoembryonic antigen (CEA) are widely accepted as markers of tuberculous pleurisy arid malignant pleural effusion respectively. We designed this study to re-evaluate the role of percutaneous pleural needle biopsy in the diagnosis of lymphocyte dominant exudative pleural effusions whose APE smear, cytologic exam was negative. METHODS: Retrospective analysis of 73 cases of percutaneous pleural needle biopsy in case of lymphocyte dominant exudative pleural effusions whose AFB smear and cytoloic exam was negative from Jan 1994 to Feb 1996 was done. RESULT: In 35 cases, specific diagnosis was obtained(all cases were tuberculous pleurisy), arid in 3(1 cases specific diagnosis was not obtained in spite of getting adequate pleural tissues, and in the other 8 cases, percutaneous pleural biopsy failed to get pleural tissues. In 9 cases, complications were combined including pneuomothorax and hemothorax. All 49 cases of pleural effusions whose ADA value was higher than 40IU/L and satisfying other categories were finally diagnosed as tuberculous pleurisy, however, the pleural biopsy confirmed only 28 cases as tuberculous pleurisy. In 6 cases of pleural effusions of which CEA value is higher than l0ng/ml, the pleural biopsy made specific diagnosis n no case. Final diagnosis of above 6 cases consisted of 4 malignant of fusions, I malignancy associated effusion and I tuberculous pleurisy. CONCLUSION: In the diagnosis of 73 cases of lymphocyte dominant pleural effusions of which acid fast bacilli smear and cytologic exam was negative, percutaneous pleural biopsy diagnosed only in 35 cases. In the diagnosis of tuberculous pleurisy, the positive predictive value of higher ADA than 40 IU/L in lymphocyte dominant pleural effusion with negative AFB smear and negative cytologic exam was l00%. And the diagnostic efficacy of pleural biopsy was 57%. In cases of effusions with high CEA than 10ng/ml 83% and 0% respectively. Finally, we concluded that percutaneous pleural needle biopsy in the diagnosis of APE smear negative and cytologic exam negative lymphocyte dominant exudative pleural effusion was not obligatory especially in effusions with high ADA and low CEA value.
Adenosine Deaminase
;
Biopsy
;
Biopsy, Needle*
;
Carcinoembryonic Antigen
;
Diagnosis*
;
Hemothorax
;
Hominidae
;
Humans
;
Lymphocytes*
;
Needles*
;
Pleural Effusion*
;
Pleural Effusion, Malignant
;
Retrospective Studies
;
Tuberculosis, Pleural
10.Rescue therapies for Helicobacter pylori infection after failure of proton pump inhibitor-based standard triple therapy.
Young Hwan SEO ; Su Yeon RHIE ; Bum Joon PARK ; Hyung Joon KIM ; Jae Gyu KIM
Korean Journal of Medicine 2008;74(1):23-29
BACKGROUND/AIMS: Proton pump inhibitor (PPI)-based standard triple therapy for Helicobacter pylori infection is widely used, but it has a considerable failure rate. The aim of this study was to evaluate the efficacy and tolerability of rescue therapies with a quadruple regimen and a rifabutin-based regimen for patients who experienced failure with PPI-based standard triple therapy. METHODS: From July 2004 through October 2006, 52 patients for whom first line triple therapy (PPI, amoxicillin and clarithromycin) had failed were included in this study. They were treated with a quadruple regimen for 7 days (PPI, bismuth, tetracycline and metronidazole) as a second line therapy. For third line therapy, a rifabutin-based regimen (PPI, rifabutin and amoxicillin) was prescribed for 14 days. The H. pylori status was determined before and at least 4 weeks after therapy by the 13C urea breath test or by endoscopy with antral and corpus biopsies for a rapid urease test, histological examination and culture. RESULTS: The mean age was 52.6 years. Thirteen patients (25%) of the 52 patients were dropped. The eradication rate of the quadruple therapy was 84.6% (33/39). Three patients of the 6 failures with quadruple therapy were then treated with the rifabutin-based regimen. The eradication rate of the rifabutin-based therapy was 100% (3/3). Adverse effects (10.2%) were reported in 4 patients who were treated with quadruple regimen. CONCLUSIONS: The quadruple regimen is still an effective second-line therapy for Korean patients who experience failure with PPI-based standard triple therapy. The rifabutin-based regimen could be used as a third-line rescue therapy in Korea.
Amoxicillin
;
Biopsy
;
Bismuth
;
Breath Tests
;
Carbamates
;
Endoscopy
;
Helicobacter
;
Helicobacter pylori
;
Humans
;
Organometallic Compounds
;
Proton Pumps
;
Protons
;
Rifabutin
;
Tetracycline
;
Urea
;
Urease