1.The Effects of Estrogen Replacement Therapy on Depressive Symptoms and Attention in Postmenopaual Woman.
Baik Seok KEE ; Sung Yeop KIM ; Bum Woo NAM ; Kyung Joon MIN ; Sang Hoo LEE
Journal of the Korean Society of Biological Psychiatry 1999;6(2):235-239
OBJECTIVES: The purpose of this study was to evaluated the difference of depressive symptoms and attention between estrogen user and non-user in postmenopausal women. METHODS: 30 Estrogen users and 30 non-users were participated in this study. They were all menopausal for at least 1 year and have 12 or more education years. We used BDI(Beck Depression Inventory), digit span and digit symbol to evaluate depressive symptoms and attention in both groups. We also measured the plasma estradiol level and identified the correlation between estradiol level and BDI, digit span and digit symbol. RESULTS: The demographic data was not different between both groups. Estrogen users scored higher than non-users in digit span(forward) and lower than non-users in BDI. The correlation between estradiol level BDI, digit span and digit symbol was not significant. CONCLUSION: Estrogen replacement therapy was effective in alleviation depressive symptoms but ineffective in improving attention in postmenopausal women.
Depression*
;
Education
;
Estradiol
;
Estrogen Replacement Therapy*
;
Estrogens*
;
Female
;
Humans
;
Plasma
2.An experimental study about efficacy of drain catheters.
Bum Gyu AHN ; Joon Young NHO ; Hyo Cheol WOO ; Woo Cheol HWANG ; Choong Ki PARK ; Jong Sup YOON
Journal of the Korean Radiological Society 1993;29(5):917-922
Although percutaneous abscess drainage has become and accepted alternative from of therapy for selected patients with abscess, it is well known that there are several factors in the failure of adequate drainage such as pre-and post- procedural management, technique itself, various features of abscess, and selection and application of catheters. Among these factors, we made an experiment about drain efficacy of commonly used various catheters with different viscosities of water-glycerin solution under the two different pressure gradients. The experimental values of flow rate were lower than than the calculated values. An efficacy of experimental value was 4-14%. Because the inner diameter of fittings and stopcocks was usually smaller than the inner diameter of catheters, these factors also affected the drain efficacy. Finally, we though that it will be very helpful to the treatment of patients as well as to study about the catheter drainage, if the drain efficacy of individual catheters has been notified.
Abscess
;
Catheters*
;
Drainage
;
Humans
;
Viscosity
3.A Case of Postauricular Dermoid Cyst.
In Hwan MOON ; Woo Hyun LEE ; Joon Bum JOO ; Ju Eun CHO
Korean Journal of Otolaryngology - Head and Neck Surgery 2005;48(10):1294-1296
Dermoid cysts are congenital anomalies that arise from trapped pouches of the ectoderm near the normal fold or from the surface ectoderm that has failed to separate from the neural tube. Dermoid cysts of head and neck area are relatively rare, whereas those located in the postauricular area are extremely rare. In Korea, only 3 cases of postauricular dermoid cysts have been reported. In this article, we report a case of postauricular dermoid cyst in a 21 year-old man, along with a review of articles.
Dermoid Cyst*
;
Ear, External
;
Ectoderm
;
Head
;
Humans
;
Korea
;
Neck
;
Neural Tube
;
Young Adult
4.A Case of Painful Post-Traumatic Trigeminal Neuropathy after Endoscopic Sinus Surgery
Junho HWANG ; Taehun LIM ; Joon Bum JOO ; Woo Hyun LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 2021;64(4):268-272
Painful post-traumatic trigeminal neuropathy (PPTTN) is a distinctive facial pain syndrome characterized by facial and/or oral pain along the sensory distribution of the fifth cranial nerve with a clear history of a traumatic event. To our knowledge, PPTTN after endoscopic sinus surgery (ESS) has not been reported in the literature. We present a case of an elderly woman who experienced unilateral neuralgic pain after undergoing ESS. Following ESS of the left sphenoid sinus to remove suspicious fungus balls, the patient complained of intermittent facial pain occurring in the left periorbital and forehead area. Clinical diagnosis of PPTTN was established after a comprehensive multidisciplinary assessment. The pain disappeared completely after a 5-week medical treatment with gabapentin. Since PPTTN cases associated with ESS are extremely rare, our case demonstrates that PPTTN should be considered in the differential diagnosis of facial pain developing after ESS and can be successfully treated with medical therapy.
5.Chronic mercury vapor poisoning of the lung plain radiograph and high resolution CT.
Choong Ki PARK ; Woo Cheol HWANG ; Joon Young NHO ; Bum Gyu AHN ; Hyo Cheol WOO ; Heung Cheol KIM ; Myoung Koo LEE
Journal of the Korean Radiological Society 1993;29(5):961-966
Authors analyzed the findings of findings of chest radiographs and high-resolution CT(HRCT) of chronic mercury vapor poisoning in 12 patients who were diagnosed by previous working history for mercury-thermometer and high level of mercury in blood and urine. The purpose of this paper is to introduce the HRCT findings of chronic mercury vapor poisoning. Duration of mercury exposure was ranged from 10 to 41 months(mean, 21.8 months). Estimated value of serum mercury was ranged from 3.6 to 8.7µg/dl(mean, 5.3 µg/dl: normal value is less than 0.5µg/dl). Estimated value of mercury in urine was ranged from 104 to 482µg/1(mean, 291.4µg/1: normal value is less than 20µg/1). Chest radiographs showed positive findings such as ground-glass opacities and peribronchial cuffings in only 2 out of 12 patients, but HRCT showed positive findings such as ground-glass opacities in 8 patients, peribronchial cuffings in 7 patients, centrilobular abnormalities in 5 patients, interface sign in 4 patients, interlobular septal thickening with intralobular lines in 2 patients and lobular consolidation in one patient. In conclusion, chest HRCT is superior to chest radiograph to show the pulmonary manifestation of chronic mercury vapor poisoning. In patients with chronic mercury vapor poisoning, HRCT findings of centrilobular distributed ground-glass opacities and peribronchial cuffinges are characteristic.
Humans
;
Lung*
;
Poisoning*
;
Radiography, Thoracic
;
Reference Values
;
Thorax
6.An Analysis of the Factors which Influence UF during Peritonitis in PD Patients.
Young Jin KIM ; Hang Jae JUNG ; Gyu Hyang JO ; Joon Bum PARK ; Jong Won PARK ; Joong Young DO ; Gyung Woo YOON
Korean Journal of Nephrology 2000;19(4):681-686
No abstract available.
Humans
;
Peritonitis*
7.Intraperitoneal Vancomycin Induced Chemical Peritonitis in CAPD Patients.
Jun Bum PARK ; Kyu Hyang JO ; Hang Jae JUNG ; Young Jin KIM ; Joon Young DO ; Kyoung Woo YOON
Korean Journal of Nephrology 1999;18(5):741-746
BACKGROUND: Intraperitoneal(IP) vancomycin has been widely used for the treatment of peritonitis or exit-site infection associated with continuous ambulatory peritoneal dialysis(CAPD). However, some previous reports in the literature have suggested that IP administration of certain vancomycin may be associated with chemical peritonitis in CAPD patients. METHODS: Between 1 February 1994 and 1 February 1997, 35 consecutive CAPD patients requiring treatment with intraperitoneal vancomycin for either exit-site infection or peritonitis in the Yeungnam University Hospital were recruited retrospectively into the study. We compared retrospectively the incidence of chemical peritonitis after using two different preparations of vancomycin from different pharmaceutical companies, namely vancocin CP(R) and vancomycin(R). RESULTS: Thirty-three cases(all 26 cases given vancocin CP(R) and 7 out of the 9 cases given vancomycin(R)) showed improvement. None of them developed fever, abdominal pain or cloudy dialysate. Out of the 9 cases given IP vancomycin(R), two who currently did not have abdominal pain and cloudy dialysis effluent develolped these symptom and sign at 5 and 6 hours after administration of IP vancomycin. The chemical peritonitis may be secondary to prolonged contact of the peritoneal membrane with one or more of the impurities present in vancomycin preparation. CONCLUSION: In summary, it is necessary for the nephrologists to be aware of the possible chemical peritonitis which can be caused by the impurities of certain brand of vancomycin.
Abdominal Pain
;
Dialysis
;
Fever
;
Humans
;
Incidence
;
Membranes
;
Peritoneal Dialysis, Continuous Ambulatory*
;
Peritonitis*
;
Retrospective Studies
;
Vancomycin*
8.Emergency Quadrido-Bentall Procedure for Aortic Rupture in a Patient with Behcet's Disease.
Sung Jun PARK ; Jeong woo LEE ; Joon Bum KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 2015;48(5):364-367
Cardiovascular involvement in cases of Behcet's disease is a rare but life-threatening condition, and prosthetic valve detachment is a frequent and serious complication attributable to Behcet's disease following the surgical repair of aortic regurgitation. We report the case of a patient with Behcet's disease presenting with contained aortic rupture around the aortic root. The patient had previously undergone aortic valve surgery three times due to recurrent prosthetic valve detachment. An emergency operation was performed, consisting of aortic root replacement (ARR) using a composite valved conduit and the replacement of the hemiarch. ARR may be an appropriate surgical option for patients with Behcet's disease in order to prevent recurrence of the disease.
Aortic Rupture*
;
Aortic Valve
;
Aortic Valve Insufficiency
;
Behcet Syndrome
;
Emergencies*
;
Extracorporeal Circulation
;
Humans
;
Recurrence
9.Establishment of Hepatocellular Cancer Induced Pluripotent Stem Cells Using a Reprogramming Technique.
Han Joon KIM ; Jaemin JEONG ; Sunhoo PARK ; Young Woo JIN ; Seung Sook LEE ; Seung Bum LEE ; Dongho CHOI
Gut and Liver 2017;11(2):261-269
BACKGROUND/AIMS: Cancer is known to be a disease by many factors. However, specific results of reprogramming by pluripotency-related transcription factors remain to be scarcely reported. Here, we verified potential effects of pluripotent-related genes in hepatocellular carcinoma cancer cells. METHODS: To better understand reprogramming of cancer cells in different genetic backgrounds, we used four liver cancer cell lines representing different states of p53 (HepG2, Hep3B, Huh7 and PLC). Retroviral-mediated introduction of reprogramming related genes (KLF4, Oct4, Sox2, and Myc) was used to induce the expression of proteins related to a pluripotent status in liver cancer cells. RESULTS: Hep3B cells (null p53) exhibited a higher efficiency of reprogramming in comparison to the other liver cancer cell lines. The reprogrammed Hep3B cells acquired similar characteristics to pluripotent stem cells. However, loss of stemness in Hep3B-iPCs was detected during continual passage. CONCLUSIONS: We demonstrated that reprogramming was achieved in tumor cells through retroviral induction of genes associated with reprogramming. Interestingly, the reprogrammed pluripotent cancer cells (iPCs) were very different from original cancer cells in terms of colony shape and expressed markers. The induction of pluripotency of liver cancer cells correlated with the status of p53, suggesting that different expression level of p53 in cancer cells may affect their reprogramming.
Carcinoma, Hepatocellular
;
Cell Line
;
Genetic Background
;
Induced Pluripotent Stem Cells*
;
Liver Neoplasms*
;
Pluripotent Stem Cells
;
Transcription Factors
;
Zidovudine
10.Two Cases with Leiomyoma of the Esophagus.
Woo Kyu JEON ; Sang Jong LEE ; Myung Sook KIM ; Man Ho LEE ; Sung Min PARK ; Bong Joon SON ; Byung Hoon LIM ; Bum Soo KIM ; Woon Ha CHANG
Korean Journal of Gastrointestinal Endoscopy 1994;14(4):418-424
Leiomyoma is the most common benign tumor of the esophagus, but it still occurs rarely as compared with the incidence of carcinoma in this area. Most of leiomyomas may manifest itself with unusual and inconsistent symptoms, and found incidentally during endoscopic or radiographic examination. Those who menifested symptoms are included as dysphagia and vague pain mostly. We experienced recently two cases with esophageal leiomyoma who underwent successful surgical resection and endoscopic enucleation, respectively.
Deglutition Disorders
;
Esophagus*
;
Incidence
;
Leiomyoma*