PURPOSE: To evaluate the refractive predictability of a partial coherence interferometry (PCI) biometry device (IOL Master(R)) for cataract surgery and to investigate factors that may affect it. METHODS: Retrospective review of 209 eyes from 151 patients that had undergone preoperative PCI biometry and an uneventful phacoemulsification cataract surgery with posterior chamber intraocular lens (IOL) implantation was conducted. Prediction error defined as the intended refraction minus the postoperative refraction in spherical equivalent (SE) and the absolute error were analyzed according to IOL calculation formulas, patient characteristics, preoperative visual acuity (VA) and refraction, posterior subcapsular cataract (PSC), signal-to-noise ratio (SNR), and axial length (AL). RESULTS: The overall refractive predictability of the PCI device was good. Generally, the SRK/T formula performed better than the SRK-II formula. Refractive predictability was slightly worse in eyes with > or =+2.0 diopters (D) of preoperative SE (with both SRK-II and SRK/T) and in eyes with an AL< or =23.0 mm (only with SRK-II. No other factors significantly affected the refractive predictability of the PCI, although poor VA, dense PSC, and poor SNR were closely interrelated. CONCLUSIONS: The SRK/T formula performed significantly better than the SRK-II formula. Eyes with an AL< or =23.0 mm were associated with significantly greater hyperopic shifts in postoperative refraction with the SRK-II formula, but not with the SRK/T formula. A preoperative SE> or =+2.0D was related to a significantly greater hyperopic shift in postoperative refraction. With proper verification of measured data and a suitable IOL calculation formula, good refractive predictability is expected from PCI biometry regardless of patient characteristics, preoperative VA, SNR, PSC, and AL.
Aged ; Aged, 80 and over ; Female ; Humans ; Interferometry/*methods ; Lens Implantation, Intraocular ; *Lenses, Intraocular ; Light ; Male ; Phacoemulsification/*methods ; *Refraction, Ocular ; Refractive Errors/*diagnosis/physiopathology ; Reproducibility of Results ; Retrospective Studies ; Visual Acuity

PURPOSE: To assess the refractive outcome of cataract surgery employing IOL master and A-scans in diabetic and non-diabetic patients METHODS: The retrospective comparative study included 205 eyes of consecutive patients who had uneventful cataract surgery implanting I-Flex IOL. Axial length was measured with IOL master and A-scan and IOL power was calculated using various formulas (SRK II, SRK/T, Haigis, Holladay). Subjects was separated into five groups according to axial length, and then the groups were divided into diabetic and non-diabetic subgroups. Differences between the predicted refraction and the actual refraction were compared and analyzed at two months after the operation. RESULTS: The mean absolute errors (MAE) of ten groups showed no significant differences. Comparing diabetic groups and non-diabetic groups, there were no statistically significant differences. Also the result of the two modalities, IOL master and A-scan, were not different in statistical analysis. CONCLUSIONS: In diabetic and non-diabetic patients, IOL master and A-scan may be the accurate methods for calculating IOL power regardless of the axial length.
Cataract ; Diabetes Mellitus ; Eye ; Humans ; Lenses, Intraocular ; Retrospective Studies

PURPOSE: This study aimed to investigate the influence of resilience and symptom experience on quality of life. METHODS: Seventy five patients in an active treatment stage were recruited from 2 hospitals between October and December 2010. A survey including perceived health status, physical functional status, the symptom experience index, resilience, and the functional assessment of cancer therapy-colorectal (FACT-C) was completed. RESULTS: The level of FACT-C was 86.61 (+/-18.91), which was higher than for patients with colostomy, but lower than for patients in a rehabilitation stage. Participants without physical functional limitations showed higher level of both resilience and quality of life. Participants with bad health status showed a lower level of both resilience and quality of life and higher level of symptom experience. The quality of life was related to the level of resilience (beta=.373), symptom experience (beta=-.292), and perceived health status (beta=-3.961). CONCLUSION: Proactive nursing approaches to manage symptoms and to improve perceived health status would enhance the quality of life of colorectal cancer patients. Furthermore, various strategies to strengthen the level of resilience should be developed.
Colorectal Neoplasms ; Colostomy ; Humans ; Quality of Life ; Resilience, Psychological

PURPOSE: This study was performed to evaluate Korean nurses' knowledge about hereditary colorectal cancer (HCRC). METHODS: A modified 15-item HCRC knowledge questionnaire was developed based on previous research. One hundred and forty-eight nurses have completed the questionnaire from February to April, 2011. RESULTS: The average score of nurses' knowledge was 11.25+/-1.54. Ninety-seven percent of nurses knew about colonoscopy check up schedule and family pedigree. However, only 20% of nurses knew about the rate of passing on mutation genes to offspring and risk of developing CRC among carriers. Only 13.5% of nurses had previous genetic education experiences. Working in oncology units, taking care of CRC patients, and participating in genetic education were not associated with nurses' HCRC knowledge. CONCLUSION: Various factors influence nurses' knowledge about HCRC. Repeated study with larger national sample of nurses is recommended to identify the factors affecting nurses' knowledge level in order to develop efficient genetic education programs for HCRC patients and their families by nurses.
Appointments and Schedules ; Colonoscopy ; Colorectal Neoplasms ; Colorectal Neoplasms, Hereditary Nonpolyposis ; Humans ; Pedigree ; Surveys and Questionnaires

No abstract available.
Arteries ; Chiropractic ; Infarction ; Manipulation, Chiropractic

Eight Beagle dogs were anesthetized and were imaged using a single channel helical CT scanner. The contrast medium used in this study was iohexol (300 mg I/ml) and doses were 0.5 ml/kg for a cine scan, 3 ml/kg for an enhanced scan. The flow rate for contrast material administration was 2 ml/sec for all scans. This study was divided into three steps, with unenhanced, cine and enhanced scans. The enhanced scan was subdivided into the arterial phase and the venous phase. All of the enhanced scans were reconstructed in 1 mm intervals and the scans were interpreted by the use of reformatted images, a cross sectional histogram, maximum intensity projection and shaded surface display. For the cine scans, optimal times were a 9-sec delay time post IV injection in the arterial phase, and an 18-sec delay time post IV injection in the venous phase. A nine-sec delay time was acceptable for the imaging of the canine hepatic arteries by CT angiography. After completion of arterial phase scanning, venous structures of the liver were well visualized as seen on the venous phase.
Angiography/methods/*veterinary ; Animals ; Contrast Media/pharmacology ; Dogs/*anatomy & histology ; Iohexol/pharmacology ; Liver/*blood supply ; Tomography, X-Ray Computed/methods/*veterinary

PURPOSE: Presenteeism is a relatively new concept in nursing describing the condition within which registered nurses (RNs) come to work while they are sick. The purpose of this study was to explore and describe presenteeism experiences among RNs in South Korea. METHODS: In this constructivist grounded theory study, a focus group interview (FGI) technique was utilized for data collection. A total of 20 RNs at one hospital in Chuncheon city joined in three different FGIs. Semistructured questions were asked in reference to their sickness experience in the workplace. Data analysis was conducted according to the constructivist grounded theory methodology. RESULTS: All participants had experiences of presenteeism. The overriding theme was "having no caring for nurses leads to losing one's nursing mind". The participants reported that due to either their personal preference or peer pressure they showed up to work, but they felt sad and their pride was hurt by the fact that there was no caring for them from other nurses. This emotional exhaustion often led to the loss of compassion and the resignation of nursing staff. CONCLUSIONS: Care for nurses in the workplace is necessary for RNs to make their presenteeism experience positive and even effective.
Adult ; *Attitude of Health Personnel ; Female ; Grounded Theory ; Humans ; Male ; Middle Aged ; Nursing Staff, Hospital/*psychology ; *Presenteeism ; Qualitative Research ; Republic of Korea ; Surveys and Questionnaires ; Workplace/*psychology

PURPOSE: This study was performed to systematically review the recently published nursing intervention studies. METHODS: The literature was identified through the Korean Education and Research Information Service (KERIS), the Korean Information Service System (KISS), and National Assembly Library websites. Key words such as breast cancer, nursing, and intervention were used. The factors analyzed are as follows: 1) the characteristics of studies and study populations, 2) the classification of interventions, 3) outcome indicators and their effects, and 4) effective interventions. RESULTS: Thirty two studies were included. Seventeen studies used a single intervention such as aerobic dance, TaiChi, foot massage, aromatherapy, or a stress-reduction method. Fifteen studies used combined interventions, including education, exercise, counseling, support, yoga or meditation. The data on 47 outcome indicators and their effects were segregated into psycho/spiritual outcomes, stress coping, physical outcomes, cardiorespiratory function, symptom management, arm and shoulder functions, fatigue, and quality of life. Some interventions had positive effects on stress, fatigue, and functions of shoulder. CONCLUSION: Various interventions are available for breast cancer patients, and some have had positive effects. However, more studies are required to develop evidence-based practice guidelines for nursing interventions.
Arm ; Aromatherapy ; Breast ; Breast Neoplasms ; Counseling ; Evidence-Based Practice ; Fatigue ; Foot ; Humans ; Information Services ; Clinical Trial ; Korea ; Massage ; Meditation ; Quality of Life ; Shoulder ; Yoga

Microglia play a key role in the immune response and inflammatory reaction that occurs in response to ischemic stroke. Activated microglia promote neuronal damage or protection in injured brain tissue. Extracellular signals polarize the microglia towards the M1/M2 phenotype. The M1/M2 phenotype microglia released pro- and anti-inflammatory cytokines which induce the activation of neural stem/progenitor cells (NSPCs). In this study, we investigated how the cytokines released by microglia affect the activation of NSPCs. First, we treated BV2 cells with a lipopolysaccharide (LPS; 20 ng/ml) for M1 phenotype microglia and interleukin-4 (IL-4; 20 ng/ml) for M2 phenotype microglia in BV2 cells. Mice were subjected to transient middle cerebral artery occlusion (tMCAO) for 1 h. In ex vivo, brain sections containing the subventricular zone (SVZ) were cultured in conditioned media of M1 and M2 phenotype-conditioned media for 3 d. We measured the expression of cytokines in the conditioned media by RT-PCR and ELISA. The M2 phenotype microglia-conditioned media led to the proliferation and neural differentiation of NSPCs in the ipsilateral SVZ after ischemic stroke. The RT-PCR and ELISA results showed that the expression of TGF-α mRNA was significantly higher in the M2 phenotype microglia-conditioned media. These data support that M2 phenotype microglia-derived TGF-α is one of the key factors to enhance proliferation and neural differntiation of NSPCs after ischemic stroke.
Animals ; Brain* ; Culture Media, Conditioned ; Cytokines ; Enzyme-Linked Immunosorbent Assay ; Infarction, Middle Cerebral Artery ; Interleukin-4 ; Lateral Ventricles ; Mice ; Microglia ; Neurons* ; Phenotype* ; RNA, Messenger ; Stem Cells* ; Stroke

PURPOSE: The present survey was conducted to investigate the perceptions among nurses of neonatal pain and the associated use of pharmacologic measures (PMs) and nonpharmacologic comfort measures (CMs) in neonatal intensive care units (NICUs). Pain perception, the necessity and actual use of PMs and CMs, and their relationships were investigated and compared according to nurses' positions, educational levels, the existence of guidelines, and prior education on neonatal pain management. METHODS: Participants were 141 nurses from five NICUs at university hospitals. A questionnaire was developed by researchers based on previous studies of neonatal pain management and current practices in surveyed NICUs. Five-point Likert scales were used to assess nurses' perceptions of pain, the necessity of PMs and CMs, and their actual use in 29 painful procedures. RESULTS: The mean scores of perceived pain and the necessity of PMs and CMs were 3.68, 2.96, and 3.79 points, respectively. The actual use of PMs and CMs was 1.67 and 2.63 points, respectively. The perceived necessity of PMs correlated with the actual use of PMs (r = .316, p < .001), and CMs were performed (r = .390, p < .001). Keeping or reading guidelines, or receiving education on pain management resulted in a higher perception of the necessity of PMs. CONCLUSION: Korean nurses in NICUs often underestimate the necessity of pain relief measures and use few PMs or CMs. Therefore, systematic approaches to implement guidelines, such as adaptation of guidelines for each NICU, dissemination of guideline content to all NICU staff, and regular measurements of compliance with the guidelines, are recommended.
Adult ; *Attitude of Health Personnel ; Cross-Sectional Studies ; Female ; Humans ; Infant, Newborn ; *Intensive Care Units, Neonatal ; Intensive Care, Neonatal/*methods ; Nursing Staff, Hospital/*psychology ; Pain/nursing ; Pain Management/*methods/psychology/*utilization ; Questionnaires ; Republic of Korea ; Young Adult