1.Benign Fibrous Histiocytoma of Spinal Cord.
Hae Joo NAM ; Won Hee CHOI ; Tae Sook LEE
Korean Journal of Pathology 1988;22(4):510-514
Fibrous histiocytoma composed of fibroblasts and histiocytes is quite variable in histologic pattern. The biologic behavior is unpredictable by histologic ground. This tumor is well-known in subcutaneous tissue and deep soft tissue, but quite rare in central nervous system. We experienced a case of the fibrous histiocytoma involving the dura mater of spinal cord in a 26 year old female patient. In gross findings, the mass was a well demarcated, ovoid mass attached to the dura matter, and measured 2.5x1.5 cm in diameter. The cut surface was rubbery, solid, gray-white or yellow. Microscopically, the lesion consisted of polyhedral cells with round or oval nuclei and faintly eosinophilic or vaculoated cytoplasm, and multinucleated giant cells. Some giant cells were Touton-type. Composing cells were bland-looking. Mitotic figures were average 3 per 10 high power fields.
Female
;
Humans
2.Malignant Mixed Mullerian Tumor of the Ovary: A case report.
Hae Joo NAM ; Won Hee CHOI ; Tae Sook LEE
Korean Journal of Pathology 1987;21(4):303-307
The clinical and pathological features of a case Malignant mixed mullerian tumor of the ovary in 45 year-old female patient with a brief review of the literature are presented. She had both ovarian tumors. The masses are multilocular cystic tumor with interspersed solid component. The cystic component is filled with serous fluid. Microscopically the tumor is composed of epithelial element & intimately related mesenchymal element. The epithelial element shows the findings of adenocarcinoma of solid, glandular and papillary growth. The mesenchymal element is composed of malignant-looking stroma with cartilage formation.
Female
;
Humans
;
Adenocarcinoma
3.A case of velamentous insertion of umbilical cord in a discordant twins conceived by in vitro fertilization.
Won Il PARK ; Jong Yun NAM ; Joo Oh KIM ; Jong Eun JOO
Korean Journal of Obstetrics and Gynecology 2000;43(10):1884-1888
No abstract available.
Fertilization in Vitro*
;
Humans
;
Twins*
;
Umbilical Cord*
4.Clinical significance of cellular immunity in the renal interstitium of IgA nephropathy.
Tae See CHUNG ; Young Joo KWON ; Won Yong CHO ; Hyoung Kyu KIM ; Nam Hee WON
Korean Journal of Nephrology 1991;10(2):157-165
No abstract available.
Glomerulonephritis, IGA*
;
Immunity, Cellular*
;
Immunoglobulin A*
5.Clinical significance of cellular immunity in the renal interstitium of IgA nephropathy.
Tae See CHUNG ; Young Joo KWON ; Won Yong CHO ; Hyoung Kyu KIM ; Nam Hee WON
Korean Journal of Nephrology 1991;10(2):157-165
No abstract available.
Glomerulonephritis, IGA*
;
Immunity, Cellular*
;
Immunoglobulin A*
6.Modulatory effects of the fruits of Tribulus terrestris L. on the function of atopic dermatitis-related calcium channels, Orai1 and TRPV3
Nam Hyun Joo ; Jung Won Hyo ; Chin Young-Won ; Kim Kyung Woo ; Bae Sang Hyo
Asian Pacific Journal of Tropical Biomedicine 2016;6(7):580-585
Objective: To examine the effects of Tribulus terrestris L. (T. terrestris) extract on the modulation of calcium channels to evaluate its use in topical agents for treatment of atopic dermatitis. Methods: The 70% methanol extract of T. terrestris was prepared. Human HEK293T cells with over-expressed calcium release-activated calcium channel protein 1 (Orai1), transient receptor potential vanilloid 1, or transient receptor potential vanilloid 3 (TRPV3) were treated with T. terrestris extract. Modulation of ion channels was measured using a conventional whole-cell patch-clamp technique. Results: T. terrestris extract (100 mg/mL) significantly inhibited Orai1 activity in Orai1-stromal interaction molecule 1 co-overexpressed HEK293T cells. In addition, T. terrestris extract significantly increased the TRPV3 activity compared with 2-Aminoethyl diphe-nylborinate (100 mmol/L), which induces the full activation of TRPV3. Conclusions: Our results suggest that T. terrestris extract may have a therapeutic po-tential for recovery of abnormal skin barrier pathologies in atopic dermatitis through modulating the activities of calcium ion channels, Orai1 and TRPV3. This is the first study to report the modulatory effect of a medicinal plant on the function of ion channels in skin barrier.
7.Histopathologic Study of the Regional Lymph Nodes Reactivity in Gastric Carcinomas.
Hae Joo NAM ; Won Hee CHOI ; Tae Sook LEE ; Suk Jae HONG
Korean Journal of Pathology 1987;21(1):1-11
This study represents the immune reaction pattern of gastric carcinoma, based on the morphologic characteristics of regional lymph nodes in the cases of stomach carcinomas. The materials were obtained from the resected specimens from 100 carcinoma patients. We chose Tsakraklides' method in classification of the structure of lymph node, which are as follows: lymphocyte predominance, germinal center predominance, unstimulated and lymphocyte depletion. The incidence was as follows: lymphocyte predominance 45, germinal center predominance 32, unstimulated 21 and lymphocyte depletion 2. In the lymph nodes of peptic ulcer, lymphocyte predominance pattern was most common. The reactivity of lymph nodes is suppressed proportionally to the severity of cancers, thus the advanced case of cancer exhibited lymphocyte depletion pattern which suggests exhaustion of immune reaction. The lymphocyte predominance pattern was frequent in superficial type and expanding type of gastric carcinoma. The cancer metastasis of lymph node in lymphocyte predominance was smaller than the other type of lymph nodes, while metastasis increased progressively higher with the orders as following: lymphocyte predominance, germinal center predominance, unstimulated and lymphocyte depletion.
Incidence
;
Neoplasm Metastasis
8.A Caes of Tinea Capitis in an Adult Due to Trichophyton Rubrum.
Ki Sung KIM ; Joo Won KIM ; Young Chul KYE ; Soo Nam KIM
Annals of Dermatology 2000;12(3):189-192
Tinea capitis in adults, especially healthy, is known to be rare but a significant increase in case has recently been observed. Trichophyton rubrum is an anthropophilic, the commonest dermatophyte affecting man but rarely involves the scalp and hair. We describe a 63-year-old healthy woman with tinea capitis due to T. rubrum who has clinical improvement after oral terbinafine therapy.
Adult*
;
Arthrodermataceae
;
Female
;
Hair
;
Humans
;
Middle Aged
;
Scalp
;
Tinea Capitis*
;
Tinea*
;
Trichophyton*
9.A STUDY ON THE BOND STRENGTH OF REINFORCED INDIRECT COMPOSITE RESINS TO DENTAL ALLOYS.
Dong Joo YOON ; Sang Wan SHIN ; yu Won SUH ; Ho Nam LIM
The Journal of Korean Academy of Prosthodontics 1999;37(5):620-639
Indirect composite resin are used as an popular effective esthetic material in prosthetic dentistry, often with metallic substructure that provides support for restorations. Recently, new indirect composite resins as a substitute of ceramic have been developed. These resins provide good esthetics, with a wide range of hue and chroma. And the flexural strength of those is in the range of 120-150MPa, which is higher than that of feldspathic ceramic, and similar tot hat of Dicor. Although it has many merits, one of the major clinical problems of composite resins is the bond failure between metal and resin due to insufficient interfacial bond strength. The purpose of this study was to evaluate shear bond strength of the reinforced indirect composite resin to dental alloys. Three different composite resin systems(Artglass . Sculpture , Targis ) as test groups and ceramic(VMK 68 ) as control group were bonded to Ni-Cr-Be alloy(Rexillium III ) and gold alloy(Dave 4). All specimens were stored at 37degrees C distilled water for 24 hours and the half of specimens were thermocycled 2000 times at temperature from 5degrees C to 60degrees C. The shear bond strengths of reinforced indirect composite resins to dental alloys were measured by using the universal testing machine, and modes of debonding were observed by stereoscope and scanning electron microscope. The results were as follows : 1. The shear bond strengths of reinforced indirect composit resins to dental alloys were approximately half those of ceramic to dental alloys(P<0.01). 2. There was no significant difference between the shear bond strength of several reinforced indirect composite resins to metal. 3. Alloy type did not affect on the shear bond strengths of resin to metal, but the shear bond strengths of ceramic to gold alloys were higher than those of ceramic to Ni-Cr alloys(P<0.05). 4. The shear bond strenghts of Artglass and Targis to gold alloys were significantly decreased after thermocycling treatment(P<0.01). 5. Sculpture showed cohesive, adhesive, and mixed failure modes, but Artglass and Targis showed adhesive or mixed failures. And ceramic showed cohesive and mixed failures.
Adhesives
;
Alloys
;
Ceramics
;
Composite Resins*
;
Dental Alloys*
;
Dentistry
;
Esthetics
;
Gold Alloys
;
Sculpture
;
Water
10.Clinical Observation on Pediatric Urolithiasis.
Korean Journal of Urology 1977;18(4):329-335
A clinical observation was made on 13 cases of pediatric urolithiasis admitted to the Department of Urology. Han Il Hospital during the period from Jan., 1971 to Dec., 1975, and the following results were obtained. 1) Among 78 cases of pediatric in-patient, 13 cases were pediatric urolithiasis, 10 cases were male and 3 cases were female. 2) Age distribution was between 2 and 13 years, showing the highest incidence in 7yrs (23.0%). 3) The etiology of urinary tract stone: 2 cases in congenital anomaly, 8 cases in idiopathic, 1 case in foreign body, 1 case in immobilization, 1 case in recurrent infection. 4) Locational distribution of urinary tract stone was 5 cases in ureter, 4 cases in bladder, 3 cases in urethra, 2 cases in kidney. 5) The largest stone extracted was 2.0cm in size. 6) The common clinical manifestation of upper urinary tract stone included flank pain (71.4). hematuria (57. 1%) and lower urinary tract stone included painful urination (85. 7%), frequent urination (71.4%). 7) The most frequent method of treatment was lithotomy(57%). 8) The results of chemical analysis of 9 urinary calculi showed ca. oxalate in 33.3%, cal. Phosphate + oxalate in 33.3%.
Age Distribution
;
Female
;
Flank Pain
;
Foreign Bodies
;
Hematuria
;
Humans
;
Immobilization
;
Incidence
;
Kidney
;
Male
;
Ureter
;
Urethra
;
Urinary Bladder
;
Urinary Calculi
;
Urination
;
Urolithiasis*
;
Urology