1.An Electron Microscopic Study of Corneal Blood Staining After Hyphema.
Journal of the Korean Ophthalmological Society 1987;28(5):917-922
The authors experienced corneal blood staining after traumatic hyphema with primary open angle glaucoma and studied corneal blood staining by electron microscope. The electron microscpic finding were as follows: 1. The destructive RBC particles were found in entire cornea except deep stroma by light microscope. 2. The destruction of endothelium and intact Descemet's membrane were found and few RBC particles in the keratocyte and interlamellar space were observed by electron microscope. 3. Amorphous granules in the superficial stroma were darker than the ones in the deep stroma by electron microscope. 4. The granules were observed between basal cell layer and wing cell layer in epithelium. We suggest that clearing mechanism of corneal blood staining are scavening action of phagocytic cells and migration from deep layer to superficial layer of granules.
Blood Stains*
;
Cornea
;
Descemet Membrane
;
Endothelium
;
Epithelium
;
Glaucoma, Open-Angle
;
Hyphema*
;
Phagocytes
2.The Effects of Several Anesthetics on Intraocular Pressure.
Kun Jung LEE ; Woo Hyun CHO ; Dong Ki LEE ; Joo Yul CHO
Korean Journal of Anesthesiology 1987;20(4):510-515
The effects of several anesthetios (thiopental, ketamine, Innoyar) and muscle relaxants (succinylcholine and vecuronium) on IOP, blood pressures and pulse rates were studied in 60 Patients ranging in are 12 to 56 years. IOP was measured with the Schiotz tonometer. In addition to tonometric determinations, the blood pressures and pulse rates were recorded. The patients were divided into 4 groups: Thiopental-succinylcholine-intubation(Group 1) ; Ketamine-succinrlcholine-intubation (Group 2) ; Innovar-succitrlcholine-intubation (Group 3) and Thiopental-vecuronium-intubation (Group 4) . The results were as follows : 1) In group 1 and 4, IOP changes following thiopental(5 mg/kg) administration showed highly significant decreases(p<0.01) after 1 minute compared with the control value. 2) In group 1 and 3, IOP changes after 1 minute following succinrlcholine administration showed mild increases and were not statistically significant(p>0.05) and in group 2, IOP changes after 5 minute following succinylcholine administration shewed highly significant increases (p<0.01) . 3) In group 3, IOP changes after 5 minutes following Innovar (1 ml/15 kg) administration showed highly significant decreases (p<0.01) compared with the control value. 4) IOP changes after 1 minute of endotracheal intubation showed highly significant inc- reases (p<0.01) in all groups compared with the control value. 7) In group 4, IOP changes following vecuronium administration instead of succinylcholine showed highly significant decreases, but could not prevent the increases in IOP following endotracheal intubation. 6) In all groups, blood pressures and pulse rates showed highly significant increases after endotracheal intubation. 7) After succinylcholine administration, blood pressures showed aignificant increases in group 1 and highly significant increases in group 2. 8) In group 2, blood pressures showed highly significant increases after ketamine administration.
Anesthetics*
;
Blood Group Antigens
;
Heart Rate
;
Humans
;
Intraocular Pressure*
;
Intubation, Intratracheal
;
Ketamine
;
Succinylcholine
;
Vecuronium Bromide
3.The Changes of IOP during General Anesthesia.
Joo Yul CHO ; Ki Hoon LEE ; Byung Nam KANG
Journal of the Korean Ophthalmological Society 1988;29(4):567-571
The effects of general anesthesia on intraocular pressure were studied in 30 patients ranging in age from 15 to 48 years old. The intraocular pressure was measured by the Schiotz tonometer. The patients were divided into 2 groups: thiopental-succinylcholine-intubation (Group 1) and thiopental-vecuronium-intubation(Group 2). The results were as follows: 1) IOPs after thiopental(5 mg/kg) administration were decreased significantly compared with the control value in both group(p<0.05). 2) IOP after succinylcholine administration were elevated, but it was not statistically significant compared with the control value. 3) IOP after vecuronium administration was decreased significantly compared with the control value(p<0.05). 4) IOP after intubation were elevated significantly compared with control value in both groups(p<0.05). 5) IOP at 10 minutes after the induction of general anesthesia was not changed compared with the control value in group 1, but was decreased significantly in group 2(p<0.05).
Anesthesia, General*
;
Humans
;
Intraocular Pressure
;
Intubation
;
Middle Aged
;
Succinylcholine
;
Vecuronium Bromide
4.Delivery of the elderly primipara.
Joo Yeon CHO ; Kwang Yul CHA ; Jung Jin KOO ; Moon Jong KIM ; Dong Hee CHOI ; Kyung Sub CHA
Korean Journal of Obstetrics and Gynecology 1991;34(9):1313-1321
5.A Case of Metastatic Conjunctival Tumor.
Tae Yoon LEE ; Joo Yul CHO ; Byung Nam KANG
Journal of the Korean Ophthalmological Society 1986;27(5):949-953
The incidence of metastasis to the eye and its related structure on recent studies appear to be more common than previous studies demonstrate. The authors experienced a case of hepatocellular carcinoma metastatic to the conjunctiva. A 48-year-old man with known hepatocellular carcinoma in the liver had a mass surrounded with blood clot on the upper palpebral conjunctiva of right eye. A biopsy demonstrated that the lesion was hepatocellular carcinoma metastatic to the conjunctiva.
Biopsy
;
Carcinoma, Hepatocellular
;
Conjunctiva
;
Humans
;
Incidence
;
Liver
;
Middle Aged
;
Neoplasm Metastasis
6.Robot-assisted Laparoscopic Nephroureterectomy with a Bladder Cuff Excision.
Sung Yul PARK ; Kang Su CHO ; Won Sik HAM ; Joo Hyoung LEE ; Hyun Min CHOI ; Koon Ho RHA
Korean Journal of Urology 2008;49(4):373-375
We report here on our technique and outcomes of the first two cases of robot-assisted laparoscopic nephroureterectomy with a bladder cuff excision(RLNU). RLNU was performed on two female patients who both had a muscle invasive lower ureter tumor. For the first step, nephroureterectomy was performed in the lateral flank position. For the second step, bladder cuff excision and bladder repair were performed in a steep Trendelenburg position. The specimen was extracted through a 6 cm sized incision in the umbilical trocar site. Both procedures were successfully completed with using the robot without conversion to open surgery. The total operative time, including the lymphadenectomy and the robot docking times, was 320 and 241 minutes, respectively, for the 2 patients. The estimated blood loss was 40 and 200 ml, respectively. The pathological examinations showed stage T3 and T2 invasive transitional cell carcinoma of the ureter. The patients' postoperative recoveries were uneventful and the bladder cuff was free of tumor. RLNU may have potential advantages over open and laparosopic surgery due to its minimal invasiveness. This approach can be an alternative to open surgery or laparoscopic technique.
Carcinoma, Transitional Cell
;
Conversion to Open Surgery
;
Female
;
Head-Down Tilt
;
Humans
;
Laparoscopy
;
Lymph Node Excision
;
Muscles
;
Operative Time
;
Resin Cements
;
Robotics
;
Surgical Instruments
;
Ureter
;
Ureteral Neoplasms
;
Urinary Bladder
7.The relation between idiopathic scoliosis and the frontal and lateral facial form.
Tae Hwan KIM ; Joo Hwan KIM ; Yae Jin KIM ; Il Sik CHO ; Yong Kyu LIM ; Dong Yul LEE
The Korean Journal of Orthodontics 2014;44(5):254-262
OBJECTIVE: The purpose of this study was to evaluate the relation between idiopathic scoliosis and facial deformity in the horizontal, vertical, and anteroposterior planes. METHODS: A total of 123 female patients aged 14 years or older, who visited the Spine Clinic at the Department of Orthopedics, Korea University Guro Hospital for treatment of idiopathic scoliosis, were enrolled. Whole-spine anteroposterior and lateral radiographs were taken with the patient in a naturally erect position, and frontal and lateral cephalograms were taken in an erect position with the Frankfort horizontal line parallel to the floor. Scoliosis was classified according to the Cobb angle and Lenke classification of six curve types. Cephalometric tracing in all cases was carried out with V-Ceph 5.5 by the same orthodontist. The Kruskal-Wallis test was performed to determine whether any relation existed between each group of the idiopathic scoliosis classification and the cephalometric measurements of frontal and lateral cephalograms. RESULTS: The measurements did not reveal any significant association between the Cobb angle and cephalometric measurements and between the curve type based on the Lenke classification and cephalometric measurements. CONCLUSIONS: Based on the results of this study, no apparent relation was observed between the severity of scoliosis and facial form variations in idiopathic scoliosis patients.
Classification
;
Congenital Abnormalities
;
Female
;
Humans
;
Korea
;
Orthopedics
;
Scoliosis*
;
Spine
8.Cervical Intracanalicular Osteochondroma in Hereditary Mutiple Exostoses: Case Report.
Joo Han KIM ; Jung Keun SUH ; Jung Yul PARK ; Tai Hyoung CHO ; Hung Seob JUNG ; Ki Chan LEE
Journal of Korean Neurosurgical Society 1996;25(1):198-203
Osteochondromas make up about 30% to 40% of benign bone tumors. Most are solitary lesions but some are multiple, usually with autosomal dominant inheritance. From 1% to 4% of osteochondromas occur in the spine, where they can cause a variety of signs and symptoms, including those of spinal cord compression. Isolated osteochondromas are usually of little significance. However, if they are located near neural structures, they may cause irritation due to mechanical compression. In patients with hereditary multiple exostoses who present with neck or back pain, and particularly in those who have neurologic symptoms in the upper or lower extremities, a diagnosis of intracanalicular osteochondroma should be presumed until proven otherwise. Computerized tomography(CT) and MRI are the imaging procedures of choice. Prompt surgical excision affords the best prognosis for these patients who have spinal cord compression secondary to intracanalicular osteochondroma.
Back Pain
;
Diagnosis
;
Exostoses*
;
Exostoses, Multiple Hereditary
;
Humans
;
Lower Extremity
;
Magnetic Resonance Imaging
;
Neck
;
Neurologic Manifestations
;
Osteochondroma*
;
Prognosis
;
Spinal Cord Compression
;
Spine
;
Wills
9.Isolated Fracture of Distal Humeral Trochlea.
Ki Won LEE ; Joo Yul BAE ; Hyung Kwon CHO ; Hee Jae WON
Journal of the Korean Society for Surgery of the Hand 2016;21(3):152-156
Isolated fracture of the distal humeral trochlea occurs while the axial load delivered to the elbow passes through the trochlear of the distal humerus. It has been rarely reported, because of those reasons. The trochlea is located deep inside of the elbow joint space and since it does not have the direct attachment with muscles or ligaments, a force is hardly transmitted directly. Also ulno-humeral joint is less influenced by compressive or shear force than radio-humeral joint. We report a case of isolated trochlear fracture with review of the literature.
Elbow
;
Elbow Joint
;
Humerus
;
Joints
;
Ligaments
;
Muscles
10.Effect of Paclitaxel Local Delivery on Neointimal Formation after Endothelial Denudation of the Rat Carotid Artery.
Myeong Chan CHO ; Nam Joo KWAK ; Hainan PIAO ; Tae Jin YOUN ; Dong Woon KIM ; Hee Yul AHN ; Young Gyu KIM ; Seung Taik KIM
Korean Circulation Journal 2000;30(2):198-207
BACKGROUND AND OBJECTIVES: Mechanisms of restenosis following successful coronary angioplasty (PTCA) are knownasvascularsmoothmuscle cells(VSMCs)proliferationandmigration, elastic recoil or vascular wall remodeling. Paclitaxel whose effect on the stabilization of microtubles leads to cell death is highly lipophilic, permitting easy pass through cell membrane, and has a long-term antiproliferative effect. This study was performed to evaluate effect of paclitaxel on VSMCs proliferation and whether locally delivered paclitaxel can prevent stenosis and neointimal formation in rat carotid artery injury model. MATERIALS AND METHODS: Cultured VSMCs were exposed to sequential concentrations of paclitaxel in vitro, and proliferation inhibition was analyzed with 3H-thymidine incorporation. Paclitaxel of a suitable concentration was applied to the endothelium-denuded carotid artery of Fisher 344 inbred rats for 20 minutes. Angiogram and morphometric analysis of carotid artery was performed after 2 weeks. RESULTS: 3H-thymidine incorporation in cultured VSMCs was decreased dose-dependently from the concentration of 0.1 micromol/L (2,454+/-149cpm/ microgram protein) to 100 micromol/L (1,323+/-69cpm/ microgram protein) of paclitaxel by single and 20-minute exposure in the presence of platelet-derived growth factor (p<0.005). In the absence of platelet-derived growth factor, the decrement of 3H-thymidine incorporation was evident above the concentration of 5 micromol/L of paclitaxel. To evaluate in vivo effect, paclitaxel (0.1 or 1 micromol/L) was administered into the endothelium-denuded carotid artery by balloon injury and incubated for 20 minutes. Percent stenoses (32.2+/-9.8%) of paclitaxel-treated group was less than those (46.3+/-7.5%) of control group on histologic analysis (p<0.01). Paclitaxel-treated group also had wider lumen on carotid angiogram and less neointimal thickening than control on histologic examination (p<0.005). CONCLUSION: Proliferation of VSMCs was effectively inhibited and neointimal formation and luminal stenosis was prevented in rat carotid artery injury model by single, brief and local delivery of low-dose paclitaxel. This strategy could be applied to clinical settings for the prevention of restenosis after PTCA.
Angioplasty
;
Animals
;
Carotid Arteries*
;
Carotid Artery Injuries
;
Cell Death
;
Cell Membrane
;
Constriction, Pathologic
;
Neointima
;
Paclitaxel*
;
Phenobarbital
;
Platelet-Derived Growth Factor
;
Rats*