No abstract available.
Humans ; Hypothyroidism* ; Siblings*

PURPOSE: We performed this study to describe the findings of MR Myelography(MRM) of herniated disc disease, spinal stenosis and spinal tumor and to evaluate the usefulness of the MRM in comparison to MRI. MATERIALS AND METHODS: MRI and MRM were performed in 31 patients with herniated disc disease(12 patients), spinal stenosis(11 patients) and spinal tumor(8 patients). MRI and MRM were done with 1.5-T Signa MR, using fat suppressed heavily T2-weighted fast spin echo technique. We retrospectively analyzed MRM images about the thecal sac indentation, compression or displacement of the nerve root, extent and degree of narrowing of spinal canal, relationship between spinal tumor and spinal cord. MRM findings were compared with MRI in all cases. RESULTS: In 18 herniated disc cases of 12 patients, focal filling defect with cutoff or displacement of the nerve root in eight cases of paracentral herniated disc was seen. Cutoff and displacement of the nerve root were more clearly delineated on MRM than rvlRI. In the patients of spinal stenosis(11 cases), hourglass deformity of the thecal sac or complete spinal block of the subarachnoid space was clearly demonstrated. The extent and severity of spinal stenosis were more accurately evaluated on MRM than MRI. MRM finding of intramedullary tumor(3 cases) was enlargement of spinal cord. Five cases of intradural extramedullary tumor showed intradural filling defect, which caused contralateral displacement of the spinal cord with meniscus sign on inferior margin of the mass. CONCLUSION: MRM shows characteristic findings of herniated disc disease, spinal stenosis and spinal tumor. MRM yields excellent definition of the thecal sac, nerve roots and nerve root sleeves in relation to herniated disc and may be more accurate in evaluation of the degree and extent of spinal stenosis than MRI.
Congenital Abnormalities ; Constriction, Pathologic ; Humans ; Intervertebral Disc Displacement ; Magnetic Resonance Imaging ; Myelography* ; Retrospective Studies ; Spinal Canal ; Spinal Cord ; Spinal Diseases ; Spinal Stenosis ; Subarachnoid Space

PURPOSE: The purpose of this study is to describe the patterns of enhancement of the herniated lumbar disc with Gd-DTPA enhanced MR imaging. MATERIALS AND METHODS: Out of 65 patients, 103 lumbar discs diagnosed to be herniated by MR image were retrospectively analyzed. The MR imaging was performed with 1.5 T MR unit, using T1- and T2- weighted sagittal and axial spin echo techniques. Contrast- enhanced T1 weighted sagittal and axial images were performed after intravenous injection of Gadopentetate-dimeglumine(Magnevist, Shering) (0.1 mmol/kg). RESULTS: Contrast enhancement was seen in 66 cases(64%). Thirteen cases of bulging disc were not enhanced. Twenty-eight cases of protruded disc showed intraannular enhancement in 23 cases, peripheral linear and irregular enhancement in each of one case, and nonenhancement in three cases. Fifty-seven cases of extruded disc showed irregular enhancement in 14 cases, peripheral linear enhancement in 12 cases, peripheral ring enhancement in five cases and intraannular enhancement in five cases. All five cases of sequestered disc showed peripheral ring enhancement. CONCLUSION: Protruded discs show intraannular enhancement frequently and sequestered discs usually show peripheral ring enhancement. Enhanced MR imaging may be helpful to evaluate the type of herniated lumbar disc and relationship among disc material, nerve root and thecal sac.
Gadolinium DTPA ; Humans ; Injections, Intravenous ; Magnetic Resonance Imaging ; Retrospective Studies

Purpose: To compare the accuracy of standard and total keratometry data obtained using the Barrett Universal II and Barrett Toric Calculator. Methods: In total, 111 eyes of 111 patients who visited our hospital for cataract surgery from February 2019 to September 2019 were included in this study. Total keratometry and standard keratometry data were obtained using the Barrett Universal II and the Barrett Toric Calculator; mean absolute errors were derived by using preoperative IOL Master 700® (Carl Zeiss Meditech AG, Jena, Germany) data and 2-month postoperative manifest refraction data. The mean absolute errors of the two methods were compared in terms of a posterior corneal astigmatism greater than 0.3 diopter (D) in patients fitted with Toric intraocular lenses. Results: Using the Barrett Universal II formula, the mean absolute error spherical equivalent difference between total keratometry and standard keratometry was 0.021 ± 0.102 D (p = 0.65) when the Barrett Toric Calculator was used. The mean absolute error differences between the two methods were 0.015 ± 0.121 D for the spherical equivalent (p = 0.80) and 0.005 ± 0.870 D for the cylinder measurement (p = 0.94). In terms of a posterior corneal astigmatism greater than 0.3 D, the mean absolute error spherical equivalent and cylinder measurement differences were -0.020 ± 0.107 D (p = 0.70) and -0.023 ± 0.055 D (p = 0.50) in patients fitted with Toric intraocular lenses. Conclusions The total keratometry method, which directly measures posterior corneal curvature, yields data comparable to those of the standard keratometry method. When the posterior corneal astigmatism was greater than 0.3 D, we found no significant difference between the total keratometry and standard keratometry data of patients fitted with Toric intraocular lenses.

Purpose: To calculate the intraocular lens (IOL) power using the Shammas-PL formula after laser in-situ keratomileusis (LASIK). Methods: Forty-one eyes of 29 patients that had undergone cataract surgery from September 2018 to September 2019 after LASIK were enrolled in this study. A preoperative AL-Scan® (Nidek Co., Gamagori, Japan) was used to measure the axial length, anterior chamber depth, and corneal curvature. An IOL power calculation was performed using the Shammas-PL (post LASIK) formula. Mean absolute error (MAE) and mean arithmetic error (MARE) were calculated using preoperative manifest refraction and postoperative manifest refraction. Results: Of the 41 eyes, 15 eyes (36.6%) were relatively hyperopic-shifted after surgery compared to the predicted refractive error before surgery, 25 eyes (61%) showed a relative myopic shift, and one eye (2.4%) showed no change with respect to the previous refractive predicted error. Refractive errors before cataract surgery were not related to myopic, emmetropic, or hyperopic shifting after surgery (p > 0.05). Conclusions When cataract surgery using the Shammas-PL formula was performed after LASIK, myopic shifting was more common than hyperopic shifting. The MAE was greater in myopic-shifted cases than that of hyperopic-shifted cases. Thus, it is better to determine IOL power toward the hyperopic side than the target refractive prediction.

Purpose: To compare the accuracy of standard and total keratometry data obtained using the Barrett Universal II and Barrett Toric Calculator. Methods: In total, 111 eyes of 111 patients who visited our hospital for cataract surgery from February 2019 to September 2019 were included in this study. Total keratometry and standard keratometry data were obtained using the Barrett Universal II and the Barrett Toric Calculator; mean absolute errors were derived by using preoperative IOL Master 700® (Carl Zeiss Meditech AG, Jena, Germany) data and 2-month postoperative manifest refraction data. The mean absolute errors of the two methods were compared in terms of a posterior corneal astigmatism greater than 0.3 diopter (D) in patients fitted with Toric intraocular lenses. Results: Using the Barrett Universal II formula, the mean absolute error spherical equivalent difference between total keratometry and standard keratometry was 0.021 ± 0.102 D (p = 0.65) when the Barrett Toric Calculator was used. The mean absolute error differences between the two methods were 0.015 ± 0.121 D for the spherical equivalent (p = 0.80) and 0.005 ± 0.870 D for the cylinder measurement (p = 0.94). In terms of a posterior corneal astigmatism greater than 0.3 D, the mean absolute error spherical equivalent and cylinder measurement differences were -0.020 ± 0.107 D (p = 0.70) and -0.023 ± 0.055 D (p = 0.50) in patients fitted with Toric intraocular lenses. Conclusions The total keratometry method, which directly measures posterior corneal curvature, yields data comparable to those of the standard keratometry method. When the posterior corneal astigmatism was greater than 0.3 D, we found no significant difference between the total keratometry and standard keratometry data of patients fitted with Toric intraocular lenses.

PURPOSE: To investigate the effects of an amniotic membrane patch on corneal epithelial thickness and formation of hemidesmosomes during corneal stromal wound healing. METHODS: A stromal wound 9 mm in diameter and 130 microm in depth was created on rabbit cornea using a microkeratome. The changes in corneal epithelial thickness and hemidesmosome formations were compared between the amniotic membrane, contact lens, and control groups. Changes in the corneal epithelium were examined using H&E staining and hemidesmosome formation was examined using an electron microscope at 2 and 4 weeks after flap removal. RESULTS: Two weeks after treatment, the corneal epithelial thickness was 95.3 +/- 6.3 microm in the amniotic membrane group being significantly thicker than 76.4 +/- 5.1 microm in the contact lens group and 68.3 +/- 6.1 microm in the control group. Furthermore, more hemidesmosome formations were observed in the amniotic membrane group compared to the other 2 groups. However, there were no significant differences in corneal epithelial thickness or hemidesmosome formation among the 3 groups at week 4. CONCLUSIONS: The amniotic membrane group showed a thicker corneal epithelium and more hemidesmosome formation than the other 2 groups 2 weeks after flap removal. Thus, the use of an amniotic membrane patch appears to be effective in the early stages of corneal stromal wound healing.
Amnion ; Cornea ; Electrons ; Epithelium, Corneal ; Hemidesmosomes ; Wound Healing

PURPOSE: To evaluate the Haigis-L method of IOL Master that does not require preoperative data for intraocular lens (IOL) power calculations and compare the results with other methods requiring preoperative data. METHODS: Fifty eyes of 25 patients who had undergone laser-assisted subepithelial keratectomy (LASEK) and were followed for 1 month or longer were selected for this study. IOL power was calculated by four different methods: clinical history method, Feiz-Mannis method, modified Masket method, and Haigis-L method. RESULTS: The mean calculated IOL powers showed the following results: clinical history method; 23.65D, Feiz-Mannis method; 24.45D, modified Masket method; 22.89D, and Haigis-L method; 23.80D. Each IOL power differed statistically from others (p=0.000). The difference between each method was analyzed by the Bonferroni test, with the Feiz-Mannis method showing the highest result and the modified Masket method, the lowest. The clinical history method and Haigis-L method presented similar results. CONCLUSIONS: For patients without data prior to corneal refractive surgery, the Haigis-L method is as accurate as the clinical history method. Therefore, comparatively accurate results can be produced in IOL power calculations using the Haigis-L method after corneal refractive surgery.
Eye ; Humans ; Keratectomy, Subepithelial, Laser-Assisted ; Lenses, Intraocular ; Refractive Surgical Procedures

PURPOSE: To assess the usefulness of MRI in preoperative diagnosis of congenital anorectal malformation MATERIALS AND METHODS: MR findings of 11 cases with surgically proved anorectal malformations were retrospectively reviewed and compared with operative findings, according to the level of atresia, the development of sphincter muscle, fistula and associated anomalies of other organs. RESULTS: Four of 11 cases were low type of anorectal atresia, 3 cases were intermediate type, and 3 cases were high type. There was one case of Currarino triad with low type of anorectal stenosis. MRI demonstrated the levels of atresia correctly in all cases and revealed fistulas in all high type of anomalies. Degrees of the development of the sphincter muscles were good in all cases of low types and fair in a case of intermediate type and an anorectal stenosis, whereas the development was poor in 2 cases of intermediate type and all 4 cases of high type. The associated anomalies in anorectal malformation were renal agenesis, congenital hip dysplasia and sacral defect with presacral teratoma in Currarino triad. CONCLUSION: MRI was a simple and useful study to confirm the level of atresia, fistula and associated anomalies in the diagnosis of the congenital anorectal malformation.
Constriction, Pathologic ; Diagnosis ; Fistula ; Hip Dislocation, Congenital ; Magnetic Resonance Imaging ; Muscles ; Retrospective Studies ; Teratoma

PURPOSE: To evaluate the reproducibility and repeatibility of biometry in cataractous eyes, pseudophakic eyes and eyes having undergone refractive surgery. The OcuScan(R)RxP, LENSTAR(R) and IOL Master(R) instruments were compared, as were. The accuracies of the refractive results after cataract surgery. METHODS: The biometries of 45 cataractous eyes, 31 pseudophakic eyes, and 32 eyes having undergone refractive surgery were measured by two practitioners using OcuScan(R)RxP, LENSTAR(R) and IOL Master(R) instruments. The paired t-test was used to compare the reproducibilities in the three groups. RESULTS: There were no differences in axial length among the groups when using any of the instruments. There was no significant difference in the repeatibility regardless of the instrument used, although. In the cataractous eyes, pseudophakic eyes and eyes with refractive surgery, OcuScan(R)RxP showed the highest repeatability. However, we knew that all three instruments were excellent in the repeatability because the difference was less than 1.5%. The Prediction error of the instruments with regard to refractive results could not be determined after cataract surgery. In some patients with severe cataract, measurement was impossible for both the LENSTAR(R) and IOL Master(R) instruments. CONCLUSIONS: In all groups, OcuScan(R)RxP, LENSTAR(R) and IOL Master(R) showed no significant differences with regard to reproducibility or prediction of refractive power after surgery. Among three groups, the repeatability was rather high in the existing ultrasound method than in the partial coherence interferometers. In some patients with severe cataract, measurement was impossible for both the LENSTAR(R) and IOL Master(R) instruments.
Biometry ; Cataract ; Eye ; Humans ; Refractive Surgical Procedures