1.A Case of the Thrombi in Left Atrial Appendage Confirmed by Transesophageal Echocardiography(TEE) in A Patient with Acute Myocardial Infarction Accompanied by Cerebral Infarction.
Byung Soo KIM ; Hyun Kuk DHO ; Do Young KANG ; Joo Yl LEE ; Moo Hyun KIM ; Young Tae KIM ; Jong Seong KIM
Korean Circulation Journal 1993;23(5):761-766
Contrary to ventricular mural thrombi, left atrial appendage thrombi are extremely rare in cerebral infarction correlated with acute myocardial infarction but they can be easily detected by transesophageal echocardiography(TEE). We expierienced a case of cerebral infarction which was suspected to be caused from the thrombi in left atrial appendage in a patient with acute myocardial infarction. The cerebral infarction was developed 2 days after myocardial infarction had been occurred and any source of the thrombi could not be detected except in left atrial appendage. The diagnosis was established by TEE and also aided by transthoracic echocardiography, brain computed tomography.
Atrial Appendage*
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Brain
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Cerebral Infarction*
;
Diagnosis
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Echocardiography
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Humans
;
Myocardial Infarction*
2.Gallbladder Dysmotility and Gallstone Development after Gastrectomy in Gastric Cancer Patients.
Young Deuk KWON ; Ki Ho PARK ; Ki Hyuk PARK ; Dae Hyun JOO ; Han Il LEE ; Sung Hwan PARK ; Yong Woon YU ; Duck Soo CHUNG ; Byung Yl CHEON
Journal of the Korean Surgical Society 2001;60(2):213-218
PURPOSE: Gallstone disease has been presumed to be a sequellae of gastrectomy. To know correlation between gallbladder disease and gastrectomy, we check anatomical and functional status of gallbladder with ultrasonogram in our study. METHODS: Gallbladder motility after gastrectomy was studied by means of measuring fasting and postprandial gallbladder volume using real time ultrasonography in 50 gastrectomized patients and in 28 controls (healthy but not operated gastric cancer patients) were selected as study subjects. RESULTS: Mean fasting and postprandial gallbladder volume was significantly increased in gastrectomized patient group (FV: 37.63+/-20.70 ml, PV: 11.50+/-10.26 ml) than control group (FV: 22.17+/-10.35 ml, PV: 5.44+/-3.67 ml, p<0.01). The ejection fraction of gallbladder in gastrectomized patient group (69.05+/-14.57%)was significantly smaller than control group (75.57+/-10.26%, p<0.05). CONCLUSION: The risk of gallbladder disease was independent of age, sex, and post-operative duration in our study. Gastrectomy may have the possibility of increasing the risk of gallbladder disease by causing gallbladder dysmotility and bile stasis. So, gallbladder motility evaluation would be helpful for prevention and understanding gallstone formation. Further study will be needed about the clinical benefits of prophylactic cholecystectomy during gastrectomy.
Bile
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Cholecystectomy
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Fasting
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Gallbladder Diseases
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Gallbladder*
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Gallstones*
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Gastrectomy*
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Humans
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Stomach Neoplasms*
;
Ultrasonography
3.Randomized, Multi-center Phase II Trial of Docetaxel Plus Cisplatin Versus Etoposide Plus Cisplatin as the First-line Therapy for Patients with Advanced Non-Small Cell Lung Cancer.
Nam Su LEE ; Hee Sook PARK ; Jong Ho WON ; Dae Sik HONG ; Su Taek UH ; Sang Jae LEE ; Joo Hang KIM ; Se Kyu KIM ; Myung Ju AHN ; Jung Hye CHOI ; Suk Chul YANG ; Jung Ae LEE ; Keun Seok LEE ; Chang Yeol YIM ; Yong Chul LEE ; Chul Soo KIM ; Moon Hee LEE ; Kab Do JUNG ; Hanlim MOON ; Yl Sub LEE
Cancer Research and Treatment 2005;37(6):332-338
PURPOSE: We prospectively conducted a multi-center, open-label, randomized phase II trial to compare the efficacy and safety of docetaxel plus cisplatin (DC) and etoposide plus cisplatin (EC) for treating advanced stage non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: Seventy-eight previously untreated patients with locally advanced, recurrent or metastatic NSCLC were enrolled in this study. The patients received cisplatin 75 mg/m2 on day 1 and either docetaxel 75 mg/m2 on day 1 or etoposide 100 mg/m2 on days 1 to 3 in the DC or EC arm, respectively, every 3 weeks. RESULTS: The objective response rate was 39.4% (15/38) and 18.4% (7/38) (p=0.023) in the DC and EC arms, respectively. The median time to progression (TTP) was 5.9 and 2.7 months (p=0.119), and the overall survival was 12.1 and 8.7 months (p=0.168) in the DC and EC arms, respectively. The prognostic factors for longer survival were an earlier disease stage (stage III, p=0.0095), the responders to DC (p=0.0174) and the adenocarcinoma histology (p=0.0454). The grades 3 and 4 toxicities were similar in both arms, with more febrile neutropenia (7.9% vs. 0%) and fatigue (7.9% vs. 0%) being noted in the DC arm. CONCLUSION: DC offered a superior overall response rate than does EC, along with tolerable toxicity profiles, although the DC drug combination did not show significantly improved survival and TTP.
Adenocarcinoma
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Arm
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Carcinoma, Non-Small-Cell Lung*
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Cisplatin*
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Etoposide*
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Fatigue
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Febrile Neutropenia
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Humans
;
Prospective Studies