1.A case of congenital cystic adenomatoid malformation of the lung.
Gi Yeon SONG ; Sun Kyu PARK ; Chan Uhng JOO ; Jung Soo KIM
Journal of the Korean Pediatric Society 1993;36(1):132-137
The congenital cystic adenomatoid malformation (CCMA) of the lung is a rare variant of congenital cystic lung disease consisted of one or usually multiple interconnecting cysts in the pulmonary parenchyma lined by cuboidal and columnar epithelium. This diease present clinically in three ways: 1) stillborn or perinatal death, 2)progress respiratory distress in the newborn, and 3)acute and chronic pulmonary infections in the older infant and child. The onset of symptoms, which are cyanosis, tachypnea, and other forms of respiratory distress, usually occurs at or shortly after birth, This manifestations are related to compression of the remained normal ung by expansion of the cysts. We have experienced a case of congenital cystic adenomatoid malformation of the lung in a 1-day-old male infant who had tachypnea. A right upper lobectomy was done with satisfactory postoperative courses clinically and radiologically at 8 months of age. A brief review of the related literature is presented.
Child
;
Cyanosis
;
Cystic Adenomatoid Malformation of Lung, Congenital*
;
Epithelium
;
Humans
;
Infant
;
Infant, Newborn
;
Lung Diseases
;
Lung*
;
Male
;
Parturition
;
Tachypnea
2.A clinical study on cardiovascular disease of children taken cardiac catheterization and cineangiography.
Gi Yeon SONG ; Seog Beom CHO ; Pyoung Han HWANG ; Chan Uhng JOO ; Jung Soo KIM
Journal of the Korean Pediatric Society 1992;35(7):949-956
No abstract available.
Cardiac Catheterization*
;
Cardiac Catheters*
;
Cardiovascular Diseases*
;
Child*
;
Cineangiography*
;
Heart Defects, Congenital
;
Humans
3.A Case of SIADH Related to Drug-indeced Generalized Maculopapular Rash.
Soon Jib YOO ; Kwang Woo LEE ; Ho Young SON ; Sung Koo KANG ; Bong Yeon CHA ; Ho Jin SONG ; Joo Yeon CHOI ; Jin No PARK ; Dong HUH
Journal of Korean Society of Endocrinology 1998;13(2):240-246
Syndrome of inappropriate antidiutetic hormone(SIADH) secretion is the most common cause of hyponatremia in clinical medicine. Before diagnosis of the SIADH is made, other causes for a decreased diluting capacity and nonosmotic stimuli for AVP release need to be rule out. Disorders associated with SIADH can be divided into 4 major etiologic groups: malignancies, pulmonary diseases, central nervous disorders, and drugs. A 45-year-old woman was admitted due to maculopapular skin eruption and fever after taking medications for fever and myalgia. Generalized tonic clonic seizure was developed nine days later, and laboratory results showed marked hyponatremia. During the evaluation, treatment, and subsequent follow-up, the diagnosis of SIADH was confirmed, but the definitive cause was obscure. With fluid restriction, sodium replacement and demeclocycline therapy, she recovered completely 6 months later. We suggest that the SIADH might be related to drug-induced generalized maculopapular rash via menmgitis-like reaction in CSF as one of systemic adverse side effects to drugs rather than direct effect of related drugs.
Clinical Medicine
;
Demeclocycline
;
Diagnosis
;
Exanthema*
;
Female
;
Fever
;
Follow-Up Studies
;
Humans
;
Hyponatremia
;
Inappropriate ADH Syndrome*
;
Lung Diseases
;
Middle Aged
;
Myalgia
;
Seizures
;
Skin
;
Sodium
4.The Efficacy of Topical Tacrolimus Ointment on Cheilitis Induced by Isotretinoin Treatment in Acne Vulgaris Patients
Chang Hwa SONG ; You Jin JUNG ; Dong Seok SHIN ; Ki Yeon KIM ; Jeong Eun KIM ; Joo Yeon KO ; Young Suck RO
Korean Journal of Dermatology 2021;59(6):468-473
Background:
Isotretinoin is a gold standard treatment for moderate to severe acne vulgaris but is associated with cheilitis. Though moisturizing agents or petrolatum have been suggested, uncomfortable isotretinoin-induced cheilitis can disrupt treatment of acne patients. Topical tacrolimus has been used in atopic dermatitis with good safety and efficacy; however, there is no study of application of topical tacrolimus in cheilitis induced by isotretinoin.
Objective:
In this study, we aimed to describe the efficacy of topical tacrolimus 0.1% ointment on cheilitis associated with isotretinoin therapy using isotretinoin cheilitis grading scale (ICGS), investigator global assessment (IGA), and patient global assessment (PGA). We also observed the side effects of topical tacrolimus ointment.
Methods:
Fifty acne vulgaris patients with isotretinoin-induced cheilitis were randomly allocated to either topical tacrolimus or petrolatum treatment using permuted-block randomization. Patients were followed-up at 4 and 8 weeks, at which cheilitis lesions were photographed and evaluated with ICGS, IGA, and PGA.
Results:
Compared to petrolatum group, tacrolimus group had greater responses to treatment as measured by mean values of ICGS, IGA, PGA at follow-up visits. Also, the ICGS decrease was larger in the tacrolimus group compared with the petrolatum group even according to isotretinoin dose.
Conclusion
Topical tacrolimus ointment had superior efficacy in treating cheilitis induced by isotretinoin compared to petrolatum. Erythema, fissures, scales, and commissures all showed better response to tacrolimus ointment. Topical tacrolimus ointment can be administered as an effective strategy in treatment of cheilitis as a complication of isotretinoin therapy and can improve compliance of acne patients.
5.The Efficacy of Topical Tacrolimus Ointment on Cheilitis Induced by Isotretinoin Treatment in Acne Vulgaris Patients
Chang Hwa SONG ; You Jin JUNG ; Dong Seok SHIN ; Ki Yeon KIM ; Jeong Eun KIM ; Joo Yeon KO ; Young Suck RO
Korean Journal of Dermatology 2021;59(6):468-473
Background:
Isotretinoin is a gold standard treatment for moderate to severe acne vulgaris but is associated with cheilitis. Though moisturizing agents or petrolatum have been suggested, uncomfortable isotretinoin-induced cheilitis can disrupt treatment of acne patients. Topical tacrolimus has been used in atopic dermatitis with good safety and efficacy; however, there is no study of application of topical tacrolimus in cheilitis induced by isotretinoin.
Objective:
In this study, we aimed to describe the efficacy of topical tacrolimus 0.1% ointment on cheilitis associated with isotretinoin therapy using isotretinoin cheilitis grading scale (ICGS), investigator global assessment (IGA), and patient global assessment (PGA). We also observed the side effects of topical tacrolimus ointment.
Methods:
Fifty acne vulgaris patients with isotretinoin-induced cheilitis were randomly allocated to either topical tacrolimus or petrolatum treatment using permuted-block randomization. Patients were followed-up at 4 and 8 weeks, at which cheilitis lesions were photographed and evaluated with ICGS, IGA, and PGA.
Results:
Compared to petrolatum group, tacrolimus group had greater responses to treatment as measured by mean values of ICGS, IGA, PGA at follow-up visits. Also, the ICGS decrease was larger in the tacrolimus group compared with the petrolatum group even according to isotretinoin dose.
Conclusion
Topical tacrolimus ointment had superior efficacy in treating cheilitis induced by isotretinoin compared to petrolatum. Erythema, fissures, scales, and commissures all showed better response to tacrolimus ointment. Topical tacrolimus ointment can be administered as an effective strategy in treatment of cheilitis as a complication of isotretinoin therapy and can improve compliance of acne patients.
6.The Clinical Characteristics of Dissociated Vertical Deviation Combined with Exotropia.
Joo Yeon OH ; Won Seok SONG ; Sang Hoon RAH
Journal of the Korean Ophthalmological Society 2002;43(1):143-148
PURPOSE: The clinical characteristics and post-operative prognosis of dissociated vertical deviation (DVD) combined with exotropia was evaluated. METHOD & MATERIALS: The clinical appearance such as the frequency of DVD, vision, amount of deviation, stereoacuity, sensory abnormality, the presence of latent nystagmus, head tilting and operation results were evaluated in patients who were diagnosed with comitant exotropia followed by surgical correction with 3 month follow-up. RESULTS: Eight (16.0%) patients had exotropia combined with DVD, the combined DVD showed an angle of vertical deviation 15.88+/-7.26 delta, for the right eye and 13.50+/-6.55 deltafor the left eye in the primary position. All but 1 patient showed subnormal stereoacuity in the Titmus stereopsis test and most showed suppression in near and far in the Worth 4 dot test. Four (50%) patients were associated with latent nystagmus and one (12.5%) patient showed head tilting. Three months after the operation, all patients showed a residual DVD under 8 delta. CONCLUSION: DVD is frequently combined with exotropia and is associated with decreased stereoacuity, latent nystagmus, head tilting, inferior oblique overaction (IOOA), and superior oblique overaction (SOOA). DVD showed no relation to the amount of deviation of exotropia but was usually associated with a small angle of exotropia (<25 delta) or large angle of exotropia (> or =50 delta). The correction of DVD with exotropia showed satisfactory results.
Depth Perception
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Exotropia*
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Follow-Up Studies
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Head
;
Humans
;
Prognosis
7.Subjective Sleep Disturbances of Factory Workers in Relation to Shift Work Schedule and Chronotype.
Pamela SONG ; Su Jung CHOI ; Eun Yeon JOO
Journal of Sleep Medicine 2016;13(2):40-45
OBJECTIVES: Shift work in Korea is most prevalent in automobile system manufacturing industries. The subjective sleep complaints and individual chronotypes of shift worker was evaluated. METHODS: A cross-sectional study was conducted among single automobile system manufacturing industries in Korea. All participants completed questionnaires about the work schedule, duration of sustained employment and various division of work. And sleep questionnaires including: Epworth Sleepiness Scale, Insomnia Severity Index, Hospital Anxiety and Depression Scale, and Morningness-Eveningness Questionnaire. RESULTS: This study enrolled 208 participants [shift workers (SWs)=142, day workers (DWs)=66]. Insomnia symptoms were significantly worse in the SW group (p<0.001). Excessive daytime sleepiness was not significantly different between groups. The evening chronotype in DWs was related to both excessive daytime sleepiness (EDS) (p=0.008) and insomnia (p=0.034). On the other hand, chronotypes in SWs were not significantly different in terms of EDS and insomnia. CONCLUSIONS: Insomnia symptoms were significant in SWs compare to DWs. In DWs the evening types were sleepier and had more insomnia symptoms than other chronotypes. The sleep symptoms are prevalent in automobile industries workers, and in part it is related to work schedule and individual chronotype.
Anxiety
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Appointments and Schedules*
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Automobiles
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Cross-Sectional Studies
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Depression
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Employment
;
Hand
;
Korea
;
Sleep Initiation and Maintenance Disorders
8.Immunohistochemical Phenotypes of Phyllodes Tumor of the Breast.
Joo Yeon SONG ; Hye Kyoung YOON
Korean Journal of Pathology 2008;42(3):151-156
BACKGROUND: The aim of the study is to evaluate the difference of immunophenotypes of stromal cells between the pure phyllodes tumor (PT) type and the co-existent type of phyllodes tumor and fibroadenoma, and between benign and malignant PT. METHODS: Immunohistochemical staining for actin, CD34, CD10, c-kit, bcl-2, p53 and MIB-1 was performed using tissue microarray blocks that contained 25 cases of pure PT (16 benign tumors, 4, borderline malignant tumors, and 5 malignant tumors) and 6 cases of co-existent type. RESULTS: The expression rates of CD34 and MIB-1 in the pure PT type were significantly higher and the expression rate of actin in the pure PT was significantly lower than that of the co-existent type. However, there were no significant differences in the bcl-2, CD10, and p53 expressions between the pure PT type and the co-existent type, and no c-kit expression was observed in both types. No significant differences in the CD34, actin, bcl-2, CD10, and p53 expressions between the benign and borderline/malignant PT cases were found. However, a significant difference of the MIB-1 expression rate was noted. CONCLUSIONS: The stromal cells of the pure PT type are regarded as less mature myofibroblasts, and the CD10 reactivity in some phyllodes tumors suggests a myoepithelial origin. The MIB-1 labeling index would be useful for the grading of phyllodes tumor.
9.Lobar agenesis of the left upper lung: a case report.
Chan Uhng JOO ; Gi Yeon SONG ; Jung Soo KIM
Journal of Korean Medical Science 1990;5(4):233-235
Lung agensis is a rare developmental anomaly. It can range from total bronchial and parechymal agensis to mild pulmonary parenchymal hypoplasia of one or both lungs. A case of lobar agenesis of the left upper lung in a 15-year-old boy is presented. The patient had mild exertional dyspnea. Pulmonary angiography revealed the absence of the left upper pulmonary artery and vein. Bronchography showed no branching of bronchus to the left upper lobe. Intravenous pyelography revealed incomplete duplication of the right urinary tract.
Abnormalities, Multiple/*radiography
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Adolescent
;
Bronchography
;
Cardiac Catheterization
;
Dyspnea/etiology
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Heart Murmurs/etiology
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Humans
;
Lung/*abnormalities
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Male
;
Pulmonary Artery/*abnormalities/radiography
;
Pulmonary Veins/*abnormalities
;
Tomography, X-Ray Computed
;
Urinary Tract/*abnormalities
;
Urography
10.Multilocular Cystic Renal Neoplasm of Low Malignant Potential: A Case Report and Literature Review
Jihyun LEE ; Dong Won KIM ; Joo Yeon SONG ; Seong Kuk YOON
Journal of the Korean Radiological Society 2022;83(1):173-177
Multilocular cystic renal neoplasm of low malignant potential (MCRNLMP) is a rare subtype of renal cell carcinoma that has a favorable outcome. Most cases of MCRNLMP usually present as distinct multilocular cystic lesions; however, they may appear as small complicated cysts with hemorrhagic components. Herein, we present a case of MCRNLMP and provide a review of the literature.