OBJECTIVE: To report a safe and minimal bleeding procedure of abdominal myomectomy and to assess perioperative morbidity associated with this procedure. METHODS: From January 1998 to April 2000, We Studies 33 gynecologic patients undergoing abdominal myomectomy at department of obstetrics and gynecology, Choon-Hae Hospital, retrospectively. Particular attention was given to intraoperative estimated blood loss, blood transfusion requirement and the febrile morbidity rate. RESULTS: Myomectomy was performed successfully in all patients for whom it was scheduled. Mean intraoperative estimated blood loss was 211.5+/-91.3 mL. Four cases (12%) had an estimated blood loss greater than 400 mL. Preoperative, intraoperative or postoperative transfusion occurred in 6 cases (18%). There were no other intraoperative complications. Febrile morbidity occurred in 6 (18%) cases. Two cases (6%) experienced wound infection. CONCLUSION: We conclude that this procedure is safe and appropriate alternative for most women who want to preserve or enhance fertility potential.
Blood Transfusion ; Female ; Fertility ; Gynecology ; Hemorrhage ; Humans ; Intraoperative Complications ; Leiomyoma ; Obstetrics ; Retrospective Studies ; Wound Infection

Thrombotic thrombocytopenic purpura(TTP) is a clinical syndrome of unknown etiology and characterized by microangiopathic hemolytic anemia, thrombocytopenia, fluctuating neurological status, renal dysfunction and fever. Systemic lupus erythromatosus(SLE) is also multisystemic disease that some of clinical features may mimic TTP. Therefore both diseases have led to diagnostic confusion. We experienced two cases with SLE who subsequently or initially developed TTP. In case 1, a 44-year old woman had 1-year previous history of SLE and presented with dyspnea. After diagnosis of thrombotic microangiopathy by renal biopsy, she was managed with steroid, cyclophosphamide pulse therapy, fresh frozen plasma infusion and plasmapheresis. She was treated by aggressive treatment; nevertheless, she died on 15th admission day. In case 2, a 22-year old man was admitted because of nausea and vomiting. SLE with TTP was diagnosed by ARA criteria and the finding of microangiopathic hemolytic anemia. He was treated with plasmapheresis, fresh frozen plasma infusion and steroid therapy. He showed clinical response to the therapy, and has shown no recurrence of disease until now on. In conclusion, we suggest that early diagnosis and prompt therapy such as plasmapheresis and plasma infusion are very important in SLE with TTP.
Adult ; Anemia, Hemolytic ; Biopsy ; Cyclophosphamide ; Diagnosis ; Dyspnea ; Early Diagnosis ; Female ; Fever ; Humans ; Nausea ; Plasma ; Plasmapheresis ; Purpura, Thrombocytopenic* ; Purpura, Thrombotic Thrombocytopenic ; Recurrence ; Thrombocytopenia ; Thrombotic Microangiopathies ; Vomiting ; Young Adult